Pharmaceutical Capsules

Product Details:

We are offering high quality of Tadalafil Api Powder. We are known for manufacturing, exporting, distributing, trading and supplying Tadalafil Api Powder  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Tadalafil Api Powder  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Tadalafil Api Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Tadalafil Api Powder as well as Intermediates of Tadalafil Api Powder.  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Tadalafil Api Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
 Tadalafil is a medication primarily used to treat erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension (PAH). Below is a detailed description of tadalafil, including its chemical properties, uses, and other relevant information:
1-[(6R,12aR)-6-(1,3-dihydro-3-methyl-1H-pyrrolo[3,4-b]quinazolin-2-yl)-3-ethyl-1,4-dihydro-2H-pyrrolo[3,4-b]quinazolin-2-yl]-3-ethyl-1H-pyrrolo[3,4-b]quinazolin-2-yl]-1H-pyrrolo[3,4-b]quinazolin-2-yl]methyl)-3-ethyl-1H-pyrrolo[3,4-b]quinazolin-2-yl-3-methyl-1H-pyrrolo[3,4-b]quinazolin-2-yl-3-methyl-1H-pyrrolo[3,4-b]quinazolin-2-yl-3-methylquinazolin.
Molecular Formula:C22H19N3O4
Molecular Weight:389.41 g/mol
CAS Number:171596-29-5
Description:Tadalafil is a selective phosphodiesterase type 5 (PDE5) inhibitor that works by relaxing the muscles and increasing blood flow to specific areas of the body. It is most commonly prescribed to treat erectile dysfunction (ED), and, in combination with other treatments, for benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension (PAH).
Physical Appearance:
Form: Yellow, crystalline powder.
Odor: Odorless.
Taste: Tasteless or slightly bitter.
Solubility:
Water: Practically insoluble in water.
Ethanol: Slightly soluble in ethanol.
Solvents: Soluble in DMSO (Dimethyl sulfoxide).
Melting Point:300°C (572°F)
Absorption: Rapidly absorbed after oral administration, with peak plasma concentrations usually reached within 2 hours.
Half-Life: Long half-life of approximately 17.5 hours, which allows for extended efficacy with once-daily or as-needed dosing.
Bioavailability: Approximately 60% when taken orally.
Metabolism: Metabolized in the liver primarily via the enzyme CYP3A4 (cytochrome P450 3A4).
Excretion: Primarily excreted in the feces, with a small amount eliminated in the urine.
Mechanism of Action:Tadalafil works by inhibiting phosphodiesterase type 5 (PDE5), an enzyme responsible for the breakdown of cGMP (cyclic guanosine monophosphate). By inhibiting PDE5, tadalafil increases the concentration of cGMP, leading to the relaxation of smooth muscle in blood vessels and increased blood flow, particularly to the penis. This allows for improved erectile function in patients with ED.
Tadalafil's ability to relax smooth muscle is also beneficial in the treatment of pulmonary hypertension and BPH.
Side Effects:
Common side effects may include:
Headache
Flushing
Nasal congestion
Indigestion
Back pain
Muscle aches

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Product Details:

We are offering high quality of Progesterone. We are known for manufacturing,exporting, distributing, trading and supplying Progesterone in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Progesterone in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Progesterone Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Progesterone as well as Intermediates of Progesterone.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Progesterone to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries

Chemical Name: Pregn-4-ene-3,20-dione
Common Name: Progesterone
CAS Number: 57-83-0
Molecular Formula: C₂₁H₃₀O₂
Molecular Weight: 314.47 g/mol
Appearance: White to off-white crystalline powder
Odor: Odorless or faint odor
Solubility: Practically insoluble in water; soluble in alcohol, acetone, dioxane, and vegetable oils
Melting Point: 126–131°C
Storage Conditions: Store in a cool, dry place at controlled room temperature (20–25°C), protected from light and moisture

Pharmacological Classification:

Class: Natural progestin; female sex hormone

Therapeutic Category: Hormone replacement, fertility treatments, gynecological therapies

Mechanism of Action:Progesterone is a steroid hormone that binds to progesterone receptors in the female reproductive system. It regulates:Ovulation,Menstrual cycle,Maintenance of pregnancy
It also transforms the endometrium for embryo implantation and reduces uterine contractions.

Applications:

Used as an Active Pharmaceutical Ingredient (API) in:

Hormone Replacement Therapy (HRT)
Luteal phase support in assisted reproductive technology (ART)
Treatment of amenorrhea, dysmenorrhea, and abnormal uterine bleeding Prevention of endometrial hyperplasia in estrogen therapy Available in oral capsules, vaginal suppositories, creams, injections (oily solutions)

Sources:Can be synthetic or bioidentical (from plant sterols like diosgenin from yam/soy) Micronized forms used to improve oral bioavailability

Side Effects:Drowsiness, dizziness,Breast tenderness,Headache, mood swings,Bloating, nausea Irregular menstrual bleeding
Rare: Allergic reactions, thromboembolic events

Precautions & Warnings:

Use with caution in patients  

Liver dysfunction

History of thromboembolism

Breast or genital cancers

Monitor blood pressure and blood glucose in long-term users

Not for use in pregnancy unless prescribed (some forms are pregnancy category B/D depending on route) Avoid alcohol and other sedatives during therapy

 

Warnings:
Breast Cancer Risk:Long-term use, especially with estrogen (in hormone replacement therapy), may increase the risk of breast cancer.

Thromboembolic Disorders:May increase the risk of blood clots (deep vein thrombosis, pulmonary embolism, stroke, myocardial infarction).

 

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Product Details:

We are offering high quality of Meropenem Sodium  We are known for manufacturing, exporting, distributing, trading and supplying Meropenem Sodium  in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Meropenem Sodium  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Meropenem Sodium  .Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Meropenem Sodium  as well as Intermediates of Meropenem Sodium  .Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Meropenem Sodium  countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Meropenem sodium is a broad-spectrum antibiotic used to treat various bacterial infections. It belongs to the class of antibiotics known as carbapenems and is effective against a wide range of Gram-positive, Gram-negative, and anaerobic bacteria.

Key Details:

Mechanism of Action:
Meropenem works by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs), disrupting the bacterial cell wall structure, causing bacterial cell death.

Indications:
Meropenem is used to treat serious infections caused by susceptible organisms, such as:

Pneumonia (including hospital-acquired and ventilator-associated pneumonia)

Complicated intra-abdominal infections

Complicated urinary tract infections

Complicated skin and soft tissue infections

Meningitis

Sepsis

Endocarditis

Peritonitis

Administration:
Meropenem is usually administered intravenously (IV), either as a slow injection or infusion. Dosing can depend on the specific infection being treated, but it is typically given every 8 hours.

Side Effects: Common side effects include:

Diarrhea

Nausea

Vomiting

Rash

Elevated liver enzymes

Allergic reactions (rare)

Serious side effects (though less common) can include seizures, severe allergic reactions, or Clostridium difficile-associated diarrhea.

Pharmacokinetics:

Absorption: Since it's given intravenously, meropenem has 100% bioavailability.

Distribution: It is widely distributed in body tissues and fluids, including the lungs, urine, and cerebrospinal fluid (CSF), making it effective for treating infections in these areas.

Metabolism: Minimal metabolism in the liver.

Excretion: It is excreted primarily in the urine, both unchanged and as metabolites.

Contraindications and Precautions:

Meropenem should be used cautiously in patients with a history of seizures, as carbapenems have been associated with an increased risk of seizures.

Caution is also advised in patients with renal impairment since the drug is eliminated via the kidneys.

It should be used with caution in patients who have a history of hypersensitivity to beta-lactam antibiotics (like penicillins and cephalosporins).

Drug Interactions:

Valproic acid: Meropenem can lower blood levels of valproic acid, potentially leading to seizures in patients taking both medications.

 

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We are offering high quality of Deflazacort. We are known for manufacturing, exporting, distributing, trading and supplying Deflazacort in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Deflazacort in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Deflazacort. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Deflazacort as well as Intermediates of Deflazacort.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Deflazacort to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central
American Countries and in European countries.
Deflazacort is a synthetic corticosteroid used for its anti-inflammatory and immunosuppressive properties. It is commonly used to treat a variety of conditions, including autoimmune disorders, allergies, and inflammatory diseases. Deflazacort is available as an API (Active Pharmaceutical Ingredient) powder, which is utilized in the formulation of oral dosage forms, such as tablets and syrups.
1. Chemical Description:
Chemical Name: 9-Fluoro-11β-hydroxy-16β-methyl-17α-pregn-1,4-diene-3,20-dione
Molecular Formula: C22H28F2O4
Molecular Weight: 392.46 g/mol
CAS Number: 14484-47-0
Deflazacort is a derivative of prednisolone and is chemically related to dexamethasone, with a fluorine atom added at the 9-position to enhance its activity.
3. Uses:
Deflazacort is used in the treatment of various conditions, such as:
Inflammatory Disorders: Rheumatoid arthritis, lupus, and other autoimmune diseases.
4. Physical Characteristics:
Appearance: Deflazacort API powder is typically a white to off-white crystalline powder.
Solubility: It is slightly soluble in water but more soluble in organic solvents such as ethanol and acetone.
Stability: The powder is generally stable when stored in dry conditions, and it should be kept away from moisture and direct sunlight to preserve its potency.
7. Side Effects:
Like other corticosteroids, deflazacort can cause a range of side effects, especially with long-term use:
Common Side Effects: Weight gain, fluid retention, increased appetite, mood swings, and sleep disturbances.
Long-Term Use Effects: Osteoporosis (bone thinning), cataracts, increased risk of infections, and elevated blood glucose levels (which may lead to diabetes).
Other Effects: Increased risk of gastrointestinal issues such as ulcers, elevated blood pressure, and thinning of the skin.
Serious Side Effects (though rare) may include:
Adrenal suppression: With long-term use, the body may stop producing natural corticosteroids, which can lead to adrenal insufficiency.
8. Precautions:
Pregnancy and Breastfeeding: Deflazacort should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus. It is also excreted in breast milk, so caution is required if used by nursing mothers.
9. Storage:
Deflazacort powder should be stored in a cool, dry place, typically at a temperature of 15°C to 30°C (59°F to 86°F).
It should be kept away from moisture, heat, and light to maintain its stability and effectiveness.
The product should be stored in airtight containers to avoid moisture exposure.

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We are offering high quality of Halobetasol Propionate. We are known for manufacturing, exporting, distributing, trading and supplying Halobetasol Propionate in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Halobetasol Propionate in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Halobetasol Propionate

Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Halobetasol Propionate  as well as Intermediates of  Halobetasol Propionate .

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Halobetasol Propionate to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Halobetasol Propionate is a potent synthetic corticosteroid primarily used in the treatment of various dermatological conditions, such as psoriasis, eczema, and dermatitis. Below are the key technical details:

Chemical Name and Structure

Chemical Name: 9-Fluoro-11β,17-dihydroxy-16β-methyl-3-oxo-1,4-androstadiene-17α-carboxylic acid 21-(3-chloro-2-fluorophenyl) ester

Molecular Formula: C22H29ClF2O4

Molecular Weight: 466.91 g/mol

CAS Number: 55043-70-4.

Indications:

Halobetasol is primarily used to treat:

Psoriasis: A chronic skin condition characterized by the rapid growth of skin cells, leading to scaling and inflammation.

Eczema (Atopic Dermatitis): An inflammatory skin condition that causes itching, redness, and swelling.

Other Inflammatory Skin Disorders: Conditions like seborrheic dermatitis and contact dermatitis

Indications

Halobetasol Propionate is prescribed for the following skin conditions:

Psoriasis: Particularly for the treatment of plaque psoriasis (thick, scaly skin patches).

Eczema: For severe forms of atopic dermatitis or other types of eczema that do not respond to less potent treatments.

Contact Dermatitis: To reduce inflammation and irritation caused by an allergic or irritant reaction to substances.

Other inflammatory skin disorders: When a potent anti-inflammatory treatment is required.

Dosage and Administration

For Adults: Apply a thin layer of Halobetasol Propionate cream, ointment, or lotion to the affected skin areas once or twice a day.

For Children: The use of Halobetasol Propionate in children under the age of 12 is generally not recommended due to the risk of side effects such as systemic corticosteroid effects.

Important Usage Notes:

Short-Term Use: Halobetasol Propionate is typically recommended for short-term use to avoid adverse effects, such as skin thinning or systemic absorption.

Not for Broken or Infected Skin: Avoid using it on skin that is broken, infected, or has open wounds unless advised by a doctor.

Do Not Use Over Large Areas: Avoid applying it to large body areas to minimize the risk of systemic side effects.

Side Effects

Common Side Effects:

Skin irritation or burning sensation

Dryness, peeling, or stinging at the site of application

Itching or redness

 

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We are offering high quality of Silodosin, We are known for manufacturing, exporting, distributing, trading and supplying Silodosin in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier

of Silodosin in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier

of Silodosin , Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Silodosin as well as Intermediates of Silodosin.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the

Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Silodosin to countries like Gulf Countries,South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Silodosin is a medication primarily used to treat benign prostatic hyperplasia (BPH), a condition in which the prostate gland enlarges, causing difficulty in urination. It belongs to the class of drugs known as alpha-1 adrenergic blockers.

Details & Description

Mechanism of Action

Silodosin works by selectively blocking alpha-1 adrenergic receptors in the prostate and bladder neck. This leads to relaxation of the smooth muscles, improving urine flow and reducing symptoms like frequent urination, difficulty starting urination, and weak stream.

Indications Benign Prostatic Hyperplasia (BPH)

Reduces urinary symptoms associated with enlarged prostate

Off-label Uses (not FDA-approved but sometimes used)

May help in urinary retention caused by neurogenic bladder

May be used in some cases of chronic prostatitis

Dosage & AdministrationTypical Dosage: 8 mg once daily, taken with foodFor patients with kidney impairment: 4 mg once daily may be prescribedSide Effects Common Retrograde ejaculation (semen enters the bladder instead of exiting through the penis) Dizziness Low blood pressure (hypotension)

Nasal congestion Serious (Rare) Severe hypotension (especially in elderly patients)

Allergic reactions (rash, swelling, breathing issues Liver function abnormalities

Precautions & Warnings Not for use in women or children

Caution in patients with severe kidney or liver disease

Can cause dizziness and fainting, so patients should avoid activities requiring alertness (e.g., driving) until they know how the drug affects them

Should not be taken with strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) as this may increase silodosin levels in the body

Drug Interactions

Other Alpha-blockers (e.g., tamsulosin, doxazosin) → Increased risk of low blood pressure

PDE5 Inhibitors (e.g., sildenafil, tadalafil) → Increased risk of hypotension

Antihypertensive medications → May enhance blood pressure-lowering effects

CYP3A4 Inhibitors (e.g., ketoconazole, clarithromycin) → May increase silodosin concentration

 Contraindications

Severe kidney (renal) or liver (hepatic) impairment

History of severe hypersensitivity to silodosin or similar drugs

 

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We are offering high quality of Benzoyl Peroxide. We are known for manufacturing, exporting, Distributing, trading and supplying Benzoyl Peroxide in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Benzoyl Peroxide in Gujarat India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Benzoyl Peroxide Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Benzoyl Peroxide as well as Intermediates of Benzoyl Peroxide.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Benzoyl Peroxide to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Product Name: Benzoyl Peroxide
Chemical Name: Dibenzoyl Peroxide
CAS No.: 94-36-0
Molecular Formula: C₁₄H₁₀O₄
Molecular Weight: 242.23 g/mol
Appearance: White to off-white crystalline powder or granules
Odor: Slight characteristic odor

Product Description : Benzoyl Peroxide is an organic peroxide widely used in pharmaceutical, cosmetic, and chemical industries. It acts as a powerful oxidizing agent and is well known for its antibacterial and keratolytic properties. In pharmaceutical and cosmetic applications, it is commonly used in the treatment of acne vulgaris, helping to reduce acne-causing bacteria and excess oil on the skin.

In industrial applications, Benzoyl Peroxide is used as a polymerization initiator in the production of plastics, resins, and rubber.

Soluble in: Organic solvents (acetone, chloroform, ether)

Slightly soluble in: Alcohol

Practically insoluble in: Water

Applications / Uses

Pharmaceutical formulations (anti-acne creams, gels, lotions)

Cosmetic products

Polymer and plastic manufacturing

Rubber and resin curing agent

Chemical synthesis as an oxidizing agent

Storage Conditions

Store in a cool, dry place

Protect from heat, light, and contamination

Keep away from reducing agents and combustible materials

Store as per manufacturer’s safety recommendations

Safety, Warnings & Precautions

Strong oxidizing agent

May cause skin and eye irritation

Avoid inhalation of dust

Use appropriate protective equipment

Not intended for internal use unless specifically formulated

Side Effects : Skin irritation, redness, or dryness,Burning or stinging sensation at the application site,Peeling or scaling of the skin ,Itching or mild swelling,Temporary skin discoloration,Rarely, severe allergic reactions such as rash, swelling, or difficulty breathing

Precautions : For external use only; do not ingest or inhale

Avoid contact with eyes, lips, mouth, and mucous membranes

Perform a patch test before first use to check skin sensitivity

Start with lower concentration and increase gradually as tolerated

Use moisturizer to reduce dryness and irritation

Avoid excessive sun exposure; use sunscreen during treatment.

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