Active Pharmaceuticals Ingredient 2

Product Details:

We are offering high quality of Theophylline API Powder. We are known for manufacturing, exporting, distributing, trading and supplying Theophylline API Powder  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Theophylline API Powder  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Theophylline API Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Theophylline API Powder as well as Intermediates of Theophylline API Powder.  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Theophylline API Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
 
Theophylline is a methylxanthine drug that has bronchodilator effects, making it useful for treating respiratory diseases like asthma and chronic obstructive pulmonary disease (COPD). It works by relaxing the muscles around the airways and stimulating the central nervous system. Below is a detailed description of Theophylline:
1. Chemical Name:
3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
2. Molecular Formula:
C7H8N4O2
3. Molecular Weight:
180.17 g/mol
4. CAS Number:
58-55-9
5. Description:
Theophylline is a bronchodilator belonging to the methylxanthine class, which includes caffeine and theobromine. Theophylline is commonly used to treat asthma, chronic bronchitis, and emphysema, as it relaxes the muscles of the airways to open them up, making breathing easier.
It also has some anti-inflammatory effects, though this is less significant than its bronchodilator action. Theophylline is available in various forms, including oral tablets, extended-release tablets, liquids, and injectable formulations.
6. Physical Appearance:
Form: White or almost white, crystalline powder.
Taste: It may have a bitter taste when in liquid form.
7. Solubility:
Theophylline is sparingly soluble in water but is soluble in alcohol and chloroform.
8. Mechanism of Action:
Adenosine Receptor Antagonism: Theophylline acts as an adenosine receptor antagonist, specifically targeting A1 and A2 receptors in the lungs. By blocking these receptors, it prevents the bronchoconstriction (narrowing of the airways) that adenosine typically promotes.
Phosphodiesterase Inhibition: It also inhibits the enzyme phosphodiesterase (PDE), leading to an increase in cAMP (cyclic adenosine monophosphate) levels. Elevated cAMP levels cause smooth muscle relaxation, thus bronchodilation (widening of the airways).
Anti-inflammatory Effects: Theophylline reduces inflammatory responses in the airways, which can help alleviate symptoms of bronchoconstriction.
CNS Stimulation: Theophylline has a mild stimulating effect on the central nervous system (CNS) and can increase alertness and mental clarity.

Additional Information:

• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: INDIA
• Production Capacity: 20 MT
• Delivery Time: PROMPT
• Packaging Details: DRUM

Product Details:

 

We are offering high quality of Levo Salbutamol POWDER. We are known for manufacturing, exporting, distributing, trading and supplying Levo Salbutamol POWDER  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Levo  Salbutamol POWDER  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Levo Salbutamol POWDER. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Levo Salbutamol POWDER as well as Intermediates of Levo Salbutamol POWDER.   Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Levo Salbutamol POWDER to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.Levosalbutamol Powder (also known as Levalbuterol Powder) is a medication primarily used to treat respiratory conditions such as asthma, chronic obstructive pulmonary disease (COPD), and bronchospasms. It belongs to the class of bronchodilators, which help relax the muscles in the airways and improve airflow to the lungs.

Detailed Description:

Active Ingredient: Levosalbutamol (Levalbuterol)

Form: Powder (for inhalation or formulation purposes)

Mechanism of Action:

Levosalbutamol is a selective beta-2 adrenergic receptor agonist that helps stimulate receptors in the lungs, leading to bronchodilation (widening of the airways).

It works by relaxing the muscles around the airways, making it easier to breathe.

Uses:

Treatment of asthma and exercise-induced bronchospasm

Management of COPD

Relief from bronchospasms in reversible obstructive airway diseases

Dosage and Administration:

Commonly used in nebulizers or dry powder inhalers (DPI)

Dosage varies based on the patient's condition and doctor’s prescription

Side Effects:

Common: Tremors, headache, palpitations, nervousness, dizziness

Severe (rare): Chest pain, rapid heartbeat, paradoxical bronchospasm

Precautions:

Use cautiously in patients with heart diseases, diabetes, and hyperthyroidism

Avoid overdose as it can cause cardiovascular effects

Storage:

Store in a cool, dry place, away from moisture and direct sunlight

Chemical Name:

(R)-(-)-4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol

Formulation & Appearance:

Fine white to off-white crystalline powder

Soluble in water and ethanol

Available as a raw pharmaceutical ingredient (API) or in dry powder inhaler (DPI) form

Pharmacological Class:

Selective β2-Adrenergic Agonist (Bronchodilator)

Mechanism of Action:

Levosalbutamol selectively stimulates β2-adrenergic receptors in the bronchial smooth muscle, leading to relaxation and dilation of airways. It helps reduce airway resistance, improving airflow in conditions like asthma and COPD.

Uses & Indications:

Treatment of bronchospasm in asthma and COPD

Relief of breathing difficulties in obstructive lung diseases

Used in nebulizers or dry powder inhalers (DPIs)

 

 

 

 

Additional Information:

• Item Code: J7612
• Production Capacity: 20mt
• Delivery Time: Prompt
• Packaging Details: 25 kgs Drum Packing

Product Details:

We are offering high quality of Tricalcium Citrate . We are known for manufacturing, exporting, distributing, trading and supplying Tricalcium Citrate   in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Tricalcium Citrate   in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Tricalcium Citrate . Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Tricalcium Citrate  as well as Intermediates of Tricalcium Citrate .  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Tricalcium Citrate  to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
 
Tricalcium Citrate is a calcium salt of citric acid, commonly used as a dietary supplement to provide calcium, an essential mineral for bone health and other physiological functions. It is a preferred form of calcium supplement because it is well-tolerated and highly bioavailable, meaning the body can absorb and use it efficiently.
Description & Properties:
Chemical Name: Tricalcium citrate
Chemical Formula: Ca₃(C₆H₅O₇)₂
Molecular Weight: 570.5 g/mol
Appearance: A white to off-white crystalline powder or granules.
Solubility: Slightly soluble in water but more soluble in acidic solutions, making it easier for the body to absorb when consumed with food or in a supplement form.
Odor: Odorless.
Uses and Applications:
Dietary Supplement: Tricalcium citrate is commonly used in calcium supplements, providing a source of calcium to prevent or treat calcium deficiencies, which may lead to conditions like osteoporosis or rickets.
Bone Health: It plays a vital role in maintaining bone density, strength, and overall skeletal health. Calcium is a crucial component of hydroxyapatite, the mineral matrix of bones.
Food and Beverage Fortification: Tricalcium citrate is added to fortified foods and beverages (such as juices, dairy substitutes, or cereals) to help ensure adequate calcium intake.
Antacid: It is sometimes used as a mild antacid to neutralize stomach acid, providing relief from conditions like heartburn or acid reflux.
Pharmaceutical Formulations: Tricalcium citrate is used in the preparation of pharmaceutical products, such as in the formulation of calcium supplements and certain types of oral medications.
Mechanism of Action:
When consumed, tricalcium citrate dissociates in the digestive system to release calcium ions (Ca²⁺), which are absorbed in the small intestine. These calcium ions play a key role in several vital functions in the body:
Bone Health: Calcium is essential for bone formation and maintenance. It helps regulate bone remodeling and ensures the bones remain strong and dense, which is important for preventing bone-related disorders like osteoporosis.
Storage Conditions: Tricalcium citrate should be stored in a cool, dry place, away from moisture and heat. It should be kept tightly closed in its original container to protect it from environmental factors.
Shelf Life: Check the expiration date on the packaging and avoid using it beyond the recommended period.

Additional Information:

• Delivery Time: Prompt
• Packaging Details: Packed in 25 Kgs HDPE Drums

Product Details:

We are offering high quality of Ofloxacin HCL powder. We are known for manufacturing, exporting, distributing, trading and supplying Ofloxacin HCL powder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Ofloxacin HCL powder in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Ofloxacin HCL powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Ofloxacin HCL powder as well as Intermediates of Ofloxacin HCL powder.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Ofloxacin HCL powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Ofloxacin is an antibiotic that is commonly used for the following infections caused by certain bacteria.

Lung infections, such as bronchitis or pneumonia

Skin infections

Certain sexually transmitted diseases, such as gonorrhea or chlamydia

Kidney or bladder infections

Prostate inflammation

Ofloxacin may not be appropriate for some of the infections listed above, depending on which germs are causing the infection. Bacteria in some locations may have developed resistance to ofloxacin, which will make it not work as well.

Ofloxacin hydrochloride is a synthetic fluoroquinolone antibiotic used to treat various bacterial infections. In its pure form, it appears as an off-white to pale yellow crystalline powder. ​

Chemical Properties: Molecular Formula: C₁₈H₂₁ClFN₃O₄​, Molecular Weight: 397.8 g/mol​,

Solubility: Ofloxacin hydrochloride is soluble in aqueous solutions with pH between 2 and 5, sparingly to slightly soluble at pH 7, and freely soluble at pH above 9. ​

Mechanism of Action: Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, repair, and recombination. This inhibition disrupts bacterial cell division and leads to cell death. ​

Clinical Uses: Ofloxacin is effective against a broad spectrum of Gram-positive and Gram-negative bacteria. It's commonly prescribed for:​  Respiratory tract infections (e.g., bronchitis, pneumonia)​

Skin and soft tissue infections​

Urinary tract infections, including cystitis and pyelonephritis​

Sexually transmitted infections, such as gonorrhea and chlamydia​

Prostatitis​

Pharmacokinetics: After oral administration, ofloxacin is rapidly absorbed, with a bioavailability of approximately 98%. It reaches peak serum concentrations within one to two hours. The elimination half-life is around 4 to 5 hours in healthy individuals and slightly longer in the elderly. Ofloxacin is primarily excreted unchanged in the urine. ​

Safety Profile: Common side effects include gastrointestinal disturbances (nausea, diarrhea), headache, and insomnia. Serious but rare adverse effects encompass tendon rupture, peripheral neuropathy, and central nervous system effects like seizures or psychosis. Caution is advised in patients with a history of tendon disorders or those concurrently using corticosteroids. ​

 Note: Ofloxacin should be used under the guidance of a healthcare professional, considering potential drug interactions and individual patient factors.

Additional Information:

• Item Code: 118120-51-7
• Delivery Time: prompt
• Packaging Details: 25kgs drum pack

Product Details:

We are offering high quality of Acebrophylline We are known for manufacturing, exporting, distributing, trading and supplying Acebrophylline in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Acebrophylline in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Acebrophylline. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Acebrophylline as well as Intermediates of Acebrophylline. Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Acebrophylline to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Acebrophylline is a mucolytic agent and bronchodilator primarily used in the treatment of respiratory conditions like asthma, chronic obstructive pulmonary disease (COPD), bronchitis, and other lung disorders. It is a combination drug derived from Ambroxol (a mucolytic agent) and Theophylline-7-acetate (a bronchodilator), which helps in reducing mucus production, clearing airways, and improving breathing.

The main action of Acebrophylline is to reduce the thickness of mucus (phlegm) in the airways, making it easier to cough it out and also relaxing the airway muscles to facilitate easy breathing.

Chemical Name: Acebrophylline
Chemical Formula: C14H20Br2N2O4
Molecular Weight: 440.13 g/mol
CAS Number: 119795-19-0
Drug Class: Bronchodilator, Mucolytic Agent

Uses of Acebrophylline:Chronic Obstructive Pulmonary Disease (COPD)

Asthma,Chronic Bronchitis,Emphysema,Cough with excessive mucus production,Respiratory tract infections with mucus congestion

Side Effects of Acebrophylline:While Acebrophylline is generally safe, some people may experience the following side effects:

Nausea or Vomiting,Headache,Dizziness,Heartburn or Acid Reflux,Increased Heart Rate (Tachycardia),Insomnia (difficulty sleeping),Skin Rash (in rare cases),Abdominal Discomfort

Precautions and Warnings:

Asthma Patients: Should be used carefully in patients with severe asthma.

Heart Conditions: Should be avoided or monitored in patients with existing heart problems, as it can increase the heart rate.

Pregnancy and Breastfeeding: Should be taken only if prescribed by a healthcare provider.

Kidney or Liver Impairment: Dose adjustment may be required in patients with kidney or liver issues.

Avoid Alcohol and Smoking: Alcohol and smoking can reduce the effectiveness of Acebrophylline and worsen respiratory conditions.

Drug Interactions:Acebrophylline may interact with the following drugs:

Antibiotics (like Ciprofloxacin, Erythromycin) – May increase side effects.

Beta-blockers (like Propranolol) – Can reduce the effect of Acebrophylline.

Steroids (like Prednisolone) – Can increase the effect of Acebrophylline.

Antiepileptic drugs – May affect the clearance of Acebrophylline.

Additional Information:

• Item Code: 96989-76-3
• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: INDIA
• Production Capacity: 1 MT
• Delivery Time: immediate
• Packaging Details: hdpe drum pack

Product Details:

We are offering high quality of Praziquantel . We are known for manufacturing, exporting, distributing, trading and supplying Praziquantel   in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Praziquantel   in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Praziquantel . Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Praziquantel  as well as Intermediates of Praziquantel .  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Praziquantel  to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Praziquantel is a medication primarily used to treat parasitic worm infections. It is effective against a variety of trematodes (flukes) and cestodes (tapeworms). Below are the detailed aspects of Praziquantel:

2. Indications:

Praziquantel is used to treat several types of parasitic infections, including:
Schistosomiasis (caused by schistosome flukes)
Cysticercosis (caused by larval stages of the pork tapeworm, Taenia solium)
Hydatid disease (caused by Echinococcus species)
Liver fluke infections (such as Fasciola species)
Tapeworm infections (such as Diphyllobothrium species)

3. Dosage:Schistosomiasis: Typically, a single dose of 40 mg/kg body weight.
Cysticercosis: The dosage may vary based on the severity, but it is commonly given as a 25 mg/kg dose taken three times a day for 10 days.
Other parasitic infections: Dosages are adjusted based on the infection and the patient’s weight.

4. Administration:Praziquantel is usually administered orally in the form of tablets. The tablets should be taken with water, and it’s often recommended to take them with food to improve absorption.

5. Side Effects:

While generally well-tolerated, side effects can occur, such as:

Gastrointestinal issues: Nausea, vomiting, abdominal pain, diarrhea.

Headache and dizziness.Fatigue or drowsiness.Rarely, allergic reactions or liver enzyme abnormalities may occur.6. Contraindications:

Pregnancy: Although praziquantel is generally considered safe in pregnancy (especially in the second and third trimesters), it should only be used if absolutely necessary, as it crosses the placental barrier.

Liver disease: It should be used cautiously in patients with severe liver impairment, as it is metabolized in the liver.

Children: The use of praziquantel in young children and infants should be closely monitored, though it is considered safe with proper dosing.

7. Drug Interactions:

Praziquantel can interact with several drugs, including:

Cimetidine (increases praziquantel levels in the blood).

Rifampin (decreases praziquantel levels).

Anticonvulsants may affect the metabolism of praziquantel.

8. Pharmacokinetics:

Absorption: Praziquantel is rapidly absorbed after oral administration and is well-distributed in tissues.

Metabolism: It is metabolized primarily in the liver.

Half-life: Approximately 1.5 to 2 hours, but this can be prolonged in cases of liver impairment.Excretion: Excreted mainly through the urine as metabolites.

Additional Information:

• Delivery Time: immediate
• Packaging Details: DRUM

Product Details:

We are offering high quality of CEFDINIR .We are known for manufacturing, exporting, distributing, trading and supplying CEFDINIR In Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of  CEFDINIR  in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of CEFDINIR  Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing CEFDINIR as well as Intermediates of CEFDINIR.Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export CEFDINIR to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Cefdinir is an antibiotic that belongs to the class of cephalosporins, which are commonly used to treat bacterial infections. It works by interfering with the synthesis of bacterial cell walls, ultimately leading to the death of the bacteria. It's a third-generation cephalosporin that is typically taken orally.
Key Details About Cefdinir:
Mechanism of Action:
Cefdinir inhibits the formation of the bacterial cell wall by binding to specific enzymes known as penicillin-binding proteins (PBPs). This prevents the bacteria from properly forming their cell wall, leading to cell death.
Common Uses:
It is primarily used to treat a variety of bacterial infections, including:
Upper respiratory infections such as sinusitis and pharyngitis.
Lower respiratory infections, including pneumonia and bronchitis.
Ear infections (otitis media).
Skin and soft tissue infections.
Urinary tract infections (UTIs).
Tonsillitis and acute exacerbations of chronic bronchitis.
Dosage Forms:
Available in capsules, oral suspension (liquid), and tablets.
The dosage depends on the infection being treated, the patient's age, and any underlying conditions.
Side Effects:Common side effects include:
Diarrhea
Nausea
Vomiting
Rash
Rare, but serious side effects can include Clostridium difficile-associated diarrhea (C. diff), allergic reactions, and liver problems.
Drug Interactions:
Cefdinir can interact with antacids or iron supplements, potentially reducing its effectiveness. It’s often recommended to take these medications at least 2 hours before or after taking cefdinir.
Contraindications:
People who are allergic to cefdinir or other cephalosporins (or penicillin, as there can be cross-reactivity) should avoid this medication.
Precautions:
Caution is needed in patients with a history of kidney disease, as the drug is eliminated through the kidneys. Dosing adjustments may be necessary.
If you experience symptoms like rash, fever, or difficulty breathing, it may indicate an allergic reaction, and you should seek medical attention immediately.
Pregnancy Category:
Cefdinir is classified as Pregnancy Category B, which means that animal studies have not shown any harm to the fetus, but there are no adequate studies in pregnant humans. It should only be used during pregnancy if the potential benefits justify the potential risks.

 

 

 

Additional Information:

• Item Code: 69004-03-1
• Delivery Time: Prompt
• Packaging Details: Packed in 25 Kgs HDPE Drums

Product Details:

We are offering high quality of Doxazosin mesylate. We are known for manufacturing,exporting, distributing, trading and supplying Doxazosin mesylate in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplierof Doxazosin mesylate in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Doxazosin mesylate Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Doxazosin mesylate as well as Intermediates of Doxazosin mesylate.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Doxazosin mesylate to countries like Gulf Countries,

South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries
Chemical Name: Doxazosin mesylate

Other Names: Doxazosin methane sulfonate; Cardura (brand name)
Molecular Formula: C23H25N5O5·CH4O3S
Molecular Weight: 547.6 g/mol (mesylate salt)
CAS Number: 77883-43-3 (mesylate salt)
Appearance: White to off-white crystalline powder
Solubility: Freely soluble in dimethyl sulfoxide (DMSO) and methanol; slightly soluble in water
Storage Conditions: Store at 2°C to 8°C (refrigerated); protect from light and moisture

Pharmacological Classification:

Drug Class: Alpha-1 adrenergic blocker (selective α1-antagonist)

Therapeutic Use: Antihypertensive agent; used in the treatment of:

High blood pressure (hypertension)

Benign prostatic hyperplasia (BPH)

Mechanism of Action:Doxazosin mesylate selectively inhibits postsynaptic alpha-1 adrenergic receptors, resulting in vasodilation of arteries and veins. This reduces peripheral vascular resistance and lowers blood pressure. In BPH, it relaxes the smooth muscles in the bladder neck and prostate, improving urine flow.

Applications:

Used in the formulation of oral tablets (typically 1 mg, 2 mg, 4 mg, and 8 mg)

API for manufacturing antihypertensive and BPH medications

Side Effects:Dizziness, headache,Fatigue, edema,Orthostatic hypotension,Nasal congestion

Rare: Priapism, hepatic dysfunction

Precautions & Warnings:

First-dose phenomenon: Risk of severe hypotension; start with a low dose

Use cautiously in patients with liver impairment

May cause dizziness—advise caution when operating machinery

Monitor blood pressure regularly

Avoid alcohol and other hypotensive agents that can potentiate effects

Additional Information:

• Delivery Time: IMMEDIATE
• Packaging Details: DRUM PACK

Product Details:

 We are offering high quality of Flunixin Meglumine Powder. We are known for manufacturing, exporting, distributing, trading and supplying Flunixin Meglumine Powder in maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Flunixin Meglumine Powder in Gujarat India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Flunixin Meglumine Powder.  Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Flunixin Meglumine Powder as well as Intermediates of Flunixin Meglumine Powder.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Flunixin Meglumine Powder wder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Flunixin meglumine is a non-steroidal anti-inflammatory drug (NSAID) commonly used in veterinary medicine. Here are its technical details:

Chemical Information:

IUPAC Name: 1-(2-methyl-3-(trifluoromethyl)-phenyl)-2-(4-(methylthio)-phenyl)-2-propyl-3,5-dioxo-pyrroline-1-acetic acid

Molecular Formula: C14H14F3N3O2S

Molecular Weight: 337.35 g/mol

CAS Number: 31262-51-8

Flunixin meglumine is a nonsteroidal anti-inflammatory drug (NSAID) primarily used in veterinary medicine. It is commonly used to treat pain and inflammation in animals, particularly in horses, cattle, and dogs. It is effective in managing conditions such as musculoskeletal pain, colic, and inflammatory disorders.

Here are some key details about Flunixin meglumine:

Chemical Structure and Properties

Chemical name: 2-methyl-3-[(2-methyl-3-fluorophenyl)-4-oxo-3-pyrimidinyl]-2H-1-benzopyran-4-carboxylate meglumine salt.

Formula: C14H12F3N3O4 • C7H17NO5.

Appearance: It is typically a white to off-white crystalline powder.

Mechanism of Action

Flunixin meglumine works by inhibiting cyclooxygenase (COX), an enzyme responsible for the production of prostaglandins. Prostaglandins are compounds that promote inflammation, pain, and fever. By inhibiting COX, flunixin helps to reduce these symptoms, making it effective for controlling pain and inflammation.

Indications

Flunixin meglumine is commonly used in:

Colic in horses: To provide relief from abdominal pain and inflammation associated with colic.

Lameness and musculoskeletal disorders in horses: To reduce pain and swelling from injuries or inflammation.

Fever and inflammation in cattle: Often used to manage fever and inflammation due to conditions like respiratory diseases or mastitis.

Pain management in small animals (e.g., dogs): Used to manage post-operative pain and musculoskeletal pain.

Side Effects and Warnings

Gastrointestinal upset: Like other NSAIDs, it can cause gastric ulcers, diarrhea, or vomiting, particularly if used for extended periods.

Renal issues: Prolonged use can lead to kidney damage, especially in animals with pre-existing renal problems.

Liver effects: Liver toxicity is also a potential concern with long-term use.

Not for use in certain animals: It is not recommended for use in pregnant or lactating animals without veterinary guidance.

 

Additional Information:

• Delivery Time: Immediate
• Packaging Details: HDPE DRUM PACK

Product Details:

We are offering high quality of Vancomycin Hydrochloride. We are known for manufacturing, exporting, distributing, trading and supplying Vancomycin Hydrochloride  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Vancomycin Hydrochloride  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Vancomycin Hydrochloride. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Vancomycin Hydrochloride as well as Intermediates of Vancomycin Hydrochloride.  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Vancomycin Hydrochloride to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
 
Vancomycin Hydrochloride is a powerful antibiotic used to treat serious infections caused by Gram-positive bacteria, particularly methicillin-resistant Staphylococcus aureus (MRSA) and other resistant organisms. It belongs to the class of glycopeptide antibiotics and works by inhibiting bacterial cell wall synthesis, ultimately causing the bacteria to rupture and die.
General Information:
Chemical Name: Vancomycin Hydrochloride.
Molecular Formula: C66H75Cl2N9O24.
CAS Number: 1404-90-6.
Drug Class: Glycopeptide antibiotic.
Uses:
Vancomycin is used to treat a variety of serious infections caused by susceptible Gram-positive bacteria, including:
Methicillin-Resistant Staphylococcus aureus (MRSA) Infections:
Used for severe skin, soft tissue, bone, joint, and bloodstream infections caused by MRSA.
Endocarditis (Heart Valve Infections):
Vancomycin is often used in combination with other antibiotics to treat infective endocarditis, particularly in patients with resistant organisms.
Streptococcal Infections:
Effective against infections caused by Streptococcus species, including severe pneumonia, bacteremia, and osteomyelitis (bone infections).
Enterococcal Infections:
Can treat Enterococcus infections, though vancomycin-resistant enterococci (VRE) are becoming a concern.
Clostridium difficile (C. difficile) Infection:
The oral form is specifically used for C. difficile-related diarrhea and colitis.
Pneumonia and Bloodstream Infections:
Often used for healthcare-associated pneumonia and bloodstream infections that are resistant to other antibiotics.
Prophylaxis in Surgery:
In some cases, vancomycin may be used before surgery to prevent infections, particularly in patients at high risk for MRSA.
Dosage and Administration:
Vancomycin is typically administered intravenously for most infections. Oral vancomycin is only used for treating C. difficile infection in the gastrointestinal tract.

Additional Information:

• Delivery Time: immediate
• Packaging Details: 25 kg drum pack

Product Details:

We are offering high quality of Potassium Chloride. We are known for manufacturing, exporting, distributing, trading and supplying Potassium Chloride in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Potassium Chloride in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Potassium Chloride. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Potassium Chloride as well as Intermediates of Potassium Chloride.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Potassium Chloride to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

1. Overview

Potassium chloride (KCl) is an essential chemical compound widely used in various industries, including agriculture, pharmaceuticals, food processing, and industrial applications. It is a white or colorless crystalline powder that is highly soluble in water.

2. Chemical Properties

Chemical Formula: KCl

Molecular Weight: 74.55 g/mol

Appearance: White crystalline powder or colorless crystals

Solubility: Highly soluble in water, slightly soluble in alcohol

Odor: Odorless

pH (aqueous solution): Neutral (6.5 - 7.5)

3. Uses & Applications

A. Agricultural Use

Used as a potassium-based fertilizer (Muriate of Potash, MOP) to improve plant growth and crop yield.

Provides potassium, an essential nutrient for plant metabolism, water retention, and enzyme activation.

B. Pharmaceutical & Medical Applications

Used in electrolyte replenishment for patients with potassium deficiency (hypokalemia).

Component in intravenous (IV) fluids to balance electrolytes in the body.

Used in salt substitutes for people with sodium-restricted diets.

C. Food Industry

Functions as a food additive (E508) to enhance flavor and maintain food stability.

Commonly found in low-sodium salt substitutes.

Used in meat processing, dairy products, and canned foods to regulate acidity.

D. Industrial Applications

Utilized in water treatment processes.

Used in drilling fluids for the oil and gas industry.

Employed in glass manufacturing and production of detergents.

4. Safety & Handling

Non-toxic in recommended amounts, but excessive ingestion can cause health issues.

Storage: Keep in a cool, dry place, away from moisture and incompatible substances (acids, strong oxidizers).

Handling Precautions: Avoid inhalation of dust; wear protective gloves and safety glasses when handling large quantities.

5. Packaging & Availability

Available in bulk bags, plastic drums, and sealed containers.

Sold in different grades: Industrial grade, Food grade, and Pharmaceutical grade.

Additional Information:

• Item Code: 3104.30.
• Production Capacity: 1 MT
• Delivery Time: immediate
• Packaging Details: DRUM PACKING

Product Details:

We are offering high quality of Simethicone . We are known for manufacturing, exporting, distributing, trading and supplying Simethicone   in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Simethicone   in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Simethicone Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Simethicone as well as Intermediates of Simethicone .  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Simethicone to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Chemical Name: Polydimethylsiloxane with silica

Molecular Formula: (C₂H₆OSi)ₙ

Molecular Weight: Variable (depends on polymer chain length)

CAS Number: 8050-81-5 (Simethicone)

IUPAC Name: Dimethylpolysiloxane with silicon dioxide

Appearance: Viscous, milky-white liquid (in emulsions) or soft solid (in capsules)

Solubility: Insoluble in water; dispersible in emulsions

Simethicone 30% Emulsion (widely used in oral formulations)

Simethicone 100% (Pure, concentrated) for specialized formulations

Food Grade Used as an anti-foaming agent (E900) in the food industry

Industrial GradeUsed in cosmetics, detergents, and lubricants

Acts as a surface-active agent, reducing the surface tension of gas bubbles in the gastrointestinal tract.

Causes small gas bubbles to merge, forming larger bubbles that are easier to pass.

Does not get absorbed into the bloodstream, making it a safe option for gas relief.

Pharmaceuticals: Used in antiflatulent medications for gas relief in adults & infants
 Food Industry: Approved as a defoaming agent (E900) in beverages and food processing
 Medical Procedures: Used in endoscopy and ultrasound to reduce gas interference
 Cosmetics & Personal Care: Used in shampoos, lotions, and creams as a defoamer
 Industrial Uses: Lubricants, water treatment, textile processing

Stability & Storage Conditions

Store at 15-30°C, away from direct sunlight and heat

Keep sealed to prevent contamination

Stable for 2-3 years under proper storage conditions

 Regulatory ComplianceUSP / BP / EP standards for pharmaceutical applications

GRAS (Generally Recognized as Safe) status by the FDA

Approved as E900 in food additives by the European Food Safety Authority (EFSA)

Additional Information:

• Production Capacity: 5000
• Delivery Time: promt
• Packaging Details: 50 kgs

Product Details:

 

We are offering high quality of Chlorhexidine .We are known for  manufacturing,exporting, distributing, trading and supplying Chlorhexidine in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. 
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Chlorhexidine in Gujarat, India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of 
Chlorhexidine .Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Chlorhexidine as well as Intermediates of Chlorhexidine.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Chlorhexidine to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Chlorhexidine Gluconate is a chemical antiseptic and disinfectant widely used in various healthcare and hygiene applications. It is known for its effectiveness in killing a broad range of bacteria, viruses, and fungi. Here's a detailed description:
Chemical Composition:
Chemical Name: 1,1'-Hexamethylenebis(5-chloro-2-(4-chlorophenyl)biguanide) gluconate
Formula: C22H30Cl2N10·C6H12O7
Chlorhexidine gluconate is a salt form of chlorhexidine, a biguanide compound. The gluconate (sugar) part enhances the solubility of chlorhexidine, making it easier to formulate into solutions or other forms.
Properties:Appearance: It is typically a colorless to pale yellow liquid (in solution) or a white crystalline powder (in its pure form).
Solubility: Chlorhexidine gluconate is highly soluble in water, allowing it to be easily applied in liquid form for disinfection purposes.
pH: It has a slightly acidic pH when in solution, making it safe for topical applications without causing significant irritation to most skin types.
Mechanism of Action:
Chlorhexidine works by disrupting the cell membrane of microorganisms. It binds to the bacterial cell wall and alters its permeability, leading to leakage of cellular contents and ultimately the death of the microbe. It has a broad antimicrobial spectrum, effective against:
Bacteria: Both Gram-positive and Gram-negative bacteria, including Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Salmonella.
Fungi: Yeasts and molds, including Candida albicans.
Viruses: Some enveloped viruses like herpes simplex. However, it is not highly effective against bacterial spores.
Uses:
Antiseptic and Disinfection:
Used in surgical scrubs for healthcare workers.
For skin disinfection before surgery.
Wound cleaning and as a topical antiseptic to prevent infection.
Oral hygiene products like mouthwashes (to treat gingivitis or periodontal diseases).
In some formulations for use in eye drops to prevent infection.
Mouthwash: Chlorhexidine gluconate is often used in mouthwashes for its antibacterial properties to reduce plaque, gingivitis, and bad breath.
Topical and Oral Formulations: It can be found in various forms, such as solutions, creams, gels, and wipes.
Surgical and Medical Device Cleaning: It is sometimes used to disinfect medical equipment and devices, such as catheters.
Side Effects and Precautions:
Irritation: In some cases, chlorhexidine can cause skin irritation or allergic reactions, especially in individuals with hypersensitivity to the compound.

 

Additional Information:

• Production Capacity: 1000
• Delivery Time: Prompt
• Packaging Details: 25 kg liquid bucket 200 kg plastic drums 1000kg IBC drums

Product Details:

We are offering high quality of Ammonium Chloride. We are known for manufacturing, exporting, distributing, trading and supplying Ammonium Chloride. in Gujarat India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Ammonium Chloride in Gujarat India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Ammonium Chloride.. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Ammonium Chloride as well as Intermediates of Ammonium Chloride.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Ammonium Chloride to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Ammonium Chloride (NH₄Cl) Powder: Description and Details

Chemical Name: Ammonium Chloride
Chemical Formula: NH₄Cl
Molecular Weight: 53.49 g/mol
Appearance: White crystalline powder
CAS Number: 12125-02-9
Physical Properties
Color: White
Form: Crystalline powder or solid
Odor: Odorless or faintly ammonia-like
Solubility: Soluble in water (approximately 37.2 g/100 mL at 20°C)
Melting Point: Sublimes at 338°C (640°F)
Density: 1.527 g/cm³
pH (in solution): Slightly acidic (around 5.5–6)
Chemical Properties
Ammonium chloride is a salt formed by the combination of ammonia (NH₃) and hydrochloric acid (HCl).
It is highly soluble in water and dissociates into ammonium (NH₄⁺) and chloride (Cl⁻) ions in aqueous solutions.
Uses ;Industrial Uses: Used in the production of fertilizers (mainly as a nitrogen source).
Used as a flux in the production of zinc and other metals to clean surfaces during smelting.Applied in the manufacture of dry cell batteries.Used in textile industries for dyeing and printing.
Laboratory Uses:Employed in chemical analysis as a reagent.
Used in protein purification processes, especially in capillary electrophoresis.
Pharmaceutical Uses:Used in some medical treatments (as an expectorant in cough syrups).
Used to treat metabolic alkalosis, as it can help acidify the blood.
Applied in veterinary medicine for certain types of urinary issues in animals.
Food Industry:Used as a food additive (E510) to regulate acidity or as an acidulant in food products.
Other Uses:Ammonium chloride is also utilized in some forms of soldering and as a component in fire extinguishing systems.
Handling and Safety
Precautions:Handle with care to avoid inhalation of the dust or prolonged skin contact.
Wear appropriate protective equipment such as gloves, goggles, and a dust mask.
Inhalation may cause irritation of the respiratory tract, while ingestion or skin contact can result in discomfort or injury.
Store in a cool, dry place, away from moisture and incompatible materials (like strong bases).
Keep containers tightly sealed.
First Aid:Inhalation: Move to fresh air, and seek medical attention if symptoms persist.
Skin Contact: Wash the affected area with plenty of water.

Additional Information:

• Production Capacity: 1 mt
• Delivery Time: prompt
• Packaging Details: DRUM

Product Details:

We are offering high quality of Niacin API. We are known for manufacturing, exporting, distributing, trading and supplying Niacin API in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Niacin API in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Niacin API. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Niacin API as well as Intermediates of Niacin API.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Niacin API to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Niacin API powder, also known as Vitamin B3 or nicotinic acid, is a pharmaceutical ingredient used in the production of medicines and supplements. It's a water-soluble B vitamin that plays a vital role in energy metabolism and other bodily functions. 

Here's a more detailed look at Niacin API powder:

Key Features and Uses:

Niacin is a B vitamin, specifically Vitamin B3, also known as nicotinic acid. 

Function:It's essential for energy metabolism, helping the body convert food into fuel (glucose) for energy production. 

Uses:Pharmaceutical Industry: Used as an API (Active Pharmaceutical Ingredient) in the formulation of various medicines and supplements. 

Treatment: Used to treat vitamin deficiencies, hyperlipidemia, and hypertriglyceridemia. 

Other Uses: Used in food enrichment (cereals, flour) and as a feed additive. 

Forms:Niacin also exists as nicotinamide (niacinamide) and related derivatives. 

Benefits: Helps maintain healthy skin, nerves, and the digestive tract. 

May help reduce LDL (bad) cholesterol and increase HDL (good) cholesterol. 

Plays a role in maintaining the health of the heart, blood vessels, and metabolism. 

 

General Information:

Name: Niacin (Vitamin B3), Chemical Name: Pyridine-3-carboxylic acid, Molecular Formula: C₆H₅NO₂, Molecular Weight: 123.11 g/mol, CAS Number: 59-67-6, Synonyms: Nicotinic acid, Vitamin B3, 3-Pyridinecarboxylic acid

Physical & Chemical Properties:

Appearance: White to off-white crystalline powder, Solubility: Slightly soluble in water, soluble in alcohol

Pharmacology & Applications:

Mechanism of Action: Niacin functions as a precursor for coenzymes NAD and NADP, which are essential for cellular metabolism, oxidation-reduction reactions, and energy production.

Dosage Forms: Tablets, capsules, extended-release formulations, and injectable solutions

Regulatory & Quality Standards:

Pharmacopoeial Standards:

USP: Complies with USP specifications, BP: Complies with BP specifications, EP: Complies with EP specifications, Purity: Typically ≥ 99%, Heavy Metals: ≤ 10 ppm, Loss on Drying: ≤ 0.5%, Residue on Ignition: ≤ 0.1%

Stability & Storage:

Storage Conditions: Store in a cool, dry place away from light and moisture.

Shelf Life: Generally 3-5 years under proper storage conditions.

Manufacturing & Suppliers:Commonly manufactured by pharmaceutical API suppliers globally.

Available in bulk for formulation in dietary supplements and pharmaceutical products.

Additional Information:

• Item Code: 2936.29
• Production Capacity: The global production capacity for niacin (vitamin B3) exceeds 150,000 tons annually
• Delivery Time: IMMEDIATE
• Packaging Details: HDPE DRUM PACK

Product Details:

We are offering high quality of Tazobactum Sodium Sterile. We are known for manufacturing, exporting, distributing, trading and supplying Tazobactum Sodium Sterile  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Tazobactum Sodium Sterile  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Tazobactum Sodium Sterile. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Tazobactum Sodium Sterile as well as Intermediates of Tazobactum Sodium Sterile.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Tazobactum Sodium Sterile to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

 

Tazobactam Sodium Sterile is a medication that is often used in combination with piperacillin as a beta-lactamase inhibitor to treat various bacterial infections. It is sterile and is administered typically via intravenous (IV) or intramuscular (IM) routes. Tazobactam works by inhibiting beta-lactamase enzymes produced by certain bacteria, which are responsible for breaking down antibiotics, particularly penicillins. When used with piperacillin, it enhances the effectiveness of the drug by preventing bacterial resistance mechanisms.

1. Chemical Name:

Sodium (Z)-3-(3-[(4-carboxyphenyl)methylthio]-2-hydroxypropylthio)-4-hydroxy-2-[(2S)-2-hydroxy-1-(hydroxyimino)-1-(hydroxymethyl)ethyl]-1-pyrrolecarboxylate

2. Molecular Formula:

C10H12N2O5S2Na

3. Molecular Weight:

308.34 g/mol

4. CAS Number:

89738-03-6 (Tazobactam sodium)

5. Description:

Tazobactam is a beta-lactamase inhibitor that is often used in combination with other antibiotics, especially piperacillin, to enhance their effectiveness against bacteria that produce beta-lactamase enzymes. Tazobactam Sodium Sterile refers to the sterile, injectable form of the medication, which is typically provided as a sodium salt for use in medical settings.

It has a broad spectrum of activity against a variety of Gram-positive, Gram-negative, and anaerobic bacteria. The combination of piperacillin and tazobactam is commonly used to treat a variety of infections, such as respiratory infections, urinary tract infections, intra-abdominal infections, skin and soft tissue infections, and bloodstream infections.

6. Physical Appearance:

Form: White to off-white crystalline powder.

Appearance in Solution: Once reconstituted, the solution should be clear and free of particles.

7. Solubility:

Tazobactam sodium is soluble in water and can be prepared as a sterile solution for intravenous (IV) or intramuscular (IM) administration.

8. Mechanism of Action:

Beta-lactamase Inhibition: Tazobactam is a beta-lactamase inhibitor. Beta-lactamases are enzymes produced by certain bacteria that can break down the beta-lactam ring in antibiotics, rendering them ineffective. By inhibiting these enzymes, tazobactam helps to protect beta-lactam antibiotics (such as piperacillin) from degradation, allowing them to remain active against the bacteria.

Tazobactam itself does not have significant antibacterial activity on its own but enhances the action of antibiotics like piperacillin that target bacterial cell wall synthesis.

Additional Information:

• Delivery Time: immediate
• Packaging Details: 25 kg drum pack

Product Details:

We are offering high quality of Triethyl Citrate. We are known for manufacturing, exporting, distributing, trading and supplying Triethyl Citrate  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Triethyl Citrate  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Triethyl Citrate. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Triethyl Citrate as well as Intermediates of Triethyl Citrate.  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Triethyl Citrate to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Triethyl Citrate is an ester of citric acid, used in a variety of applications, primarily in the cosmetic, pharmaceutical, and food industries. It is a colorless, odorless liquid with a mild, slightly fruity taste and is known for its versatility as a plasticizer, solvent, and stabilizing agent.
Here are the key details about Triethyl Citrate:
1. Chemical Structure and Properties
Chemical Name: Triethyl 2-hydroxypropane-1,2,3-tricarboxylate
Molecular Formula: C9H16O7
Appearance: Colorless to pale yellow liquid.
Molecular Weight: 248.22 g/mol.
Boiling Point: 250°C (482°F).
Solubility: It is soluble in ethanol, ether, and most organic solvents but only slightly soluble in water.
2. Production
Triethyl Citrate is synthesized by esterifying citric acid with ethanol. The reaction is typically catalyzed by an acid or base, resulting in the formation of the ester along with water as a byproduct. This process is usually carried out under controlled conditions to ensure the proper ratio of reactants and high purity of the product.
3. Uses and Applications
Triethyl Citrate has various uses in different industries:
Cosmetics and Personal Care
Plasticizer for Nail Polish: Triethyl Citrate is commonly used as a plasticizer in nail polish formulations. It helps improve the flexibility and durability of the polish, preventing it from becoming brittle.
Fragrance Fixative: It can serve as a fragrance fixative in perfumes, ensuring that the scent lasts longer.
Skin Conditioning Agent: It is used in skin-care products, such as creams and lotions, due to its ability to act as a mild solvent and emulsifier.
Antiperspirants and Deodorants: It is used as a solvent for active ingredients and helps improve the stability and effectiveness of the product.
Solvent and Stabilizer: Triethyl Citrate is used in pharmaceutical formulations, particularly in oral and topical dosage forms, as a solvent for active ingredients. It can also help stabilize the formulations.
Plasticizer in Drug Delivery Systems: It is used in some drug delivery systems, including controlled-release tablets or patches, to provide flexibility to the polymer matrix.
Industrial Applications
Plasticizer: In the manufacture of plastics, particularly those used in medical devices and packaging materials, Triethyl Citrate can function as a plasticizer to improve the flexibility and processing characteristics of materials.

Additional Information:

• Delivery Time: immediate
• Packaging Details: Drum pack

Product Details:

We are offering high quality of Cinnarazine.We are known for manufacturing, exporting, distributing, trading and supplying Cinnarazine in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Cinnarazine in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Cinnarazine owadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Cinnarazine as well as Intermediates of Cinnarazine.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Cinnarazine to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Cinnarizine is an antihistamine primarily used to treat motion sickness, nausea, and vertigo, as well as for some other conditions related to dizziness and balance disorders. It is often used in the treatment of conditions like Ménière's disease, which is characterized by dizziness, tinnitus (ringing in the ears), and hearing loss.
Here’s a detailed description of cinnarizine:
Chemical Classification:
Class: First-generation antihistamine, antiemetic, and antivertigo agent.
Chemical Name: 1-[(4-chlorophenyl)(2-phenylthiazol-5-yl)methyl]piperazine.
Molecular Formula: C21H22ClN3S
Mechanism of Action:
Cinnarizine works by blocking the action of histamine at histamine receptors (particularly H1 receptors). It also has anticholinergic properties, which means it can inhibit certain neurotransmitters involved in nausea and vomiting. These actions help to reduce the symptoms of motion sickness and balance disorders. Additionally, cinnarizine has some direct effects on the vestibular system, which is responsible for maintaining balance.
Uses:
Motion Sickness: Cinnarizine is effective in preventing and treating symptoms of motion sickness such as nausea, vomiting, and dizziness, typically induced by travel (car, boat, plane, etc.).
Vertigo and Balance Disorders: It is used for treating conditions that cause vertigo (a spinning sensation), particularly when the underlying issue is related to the vestibular system, such as in Ménière's disease.
Nausea and Vomiting: It can be used to reduce nausea and vomiting, especially in cases related to inner ear problems or as a result of motion.
Allergic Reactions: As a first-generation antihistamine, cinnarizine may also be used for managing allergic symptoms such as itching, rashes, and sneezing.
Dosage and Administration:
The typical adult dose is 25–75 mg per day, divided into two or three doses.
For motion sickness, it's often recommended to take the drug 1-2 hours before the journey.
For vertigo, treatment doses usually begin at 25 mg two to three times a day.
Side Effects:
Common Side Effects:
Drowsiness and sedation (since cinnarizine is a first-generation antihistamine)
Dry mouth
Blurred vision
Constipation
Urinary retention
Less Common:
Dizziness
Weight gain
Hypersensitivity reactions such as rashes, itching, or swelling
Gastrointestinal issues like nausea or upset stomach

 

 

Additional Information:

• Item Code: 298-57-7
• Production Capacity: 1 MT
• Delivery Time: Prompt
• Packaging Details: Drum

Product Details:

We are offering high quality of Haloperidol powder. We are known for manufacturing, exporting, distributing, trading and supplying Haloperidol powder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Haloperidol powder in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Haloperidol powder.

Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Haloperidol powder as well as Intermediates of  Haloperidol powder.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Haloperidol powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Haloperidol is an antipsychotic medication primarily used to treat conditions such as schizophrenia, acute psychosis, and in some cases, for controlling tics or vocal utterances in Tourette's syndrome. Below are the key technical details about Haloperidol:

1. Chemical Information

Chemical Name: 4-[4-(p-Fluorobenzoyl)-1-piperazinyl]-1-(4-piperidyl)-1,2-dihydro-2-thioxo-3H-1,4-benzodiazepine

IUPAC Name: 4-[4-(P-fluorobenzoyl)-1-piperazinyl]-1-(4-piperidyl)-1,2-dihydro-2-thioxo-3H-1,4-benzodiazepine

Molecular Formula: C21H23ClFNO2S

Molecular Weight: 375.93 g/mol

CAS Number: 52-86-8

2. Pharmacodynamics

Mechanism of Action: Haloperidol is a dopamine antagonist, primarily blocking dopamine receptors (D2) in the brain. It reduces the effects of dopamine, which helps alleviate symptoms of psychosis and mania.

Therapeutic Class: Antipsychotic (First-generation or typical antipsychotic)

Pharmacological Effects:

Central Nervous System: Reduces symptoms of psychosis (delusions, hallucinations) and controls behavior.

Extrapyramidal Effects: Can lead to side effects like tardive dyskinesia and Parkinson-like symptoms due to dopamine blockade.

3. Pharmacokinetics

Absorption: Haloperidol is well absorbed orally, with peak plasma levels occurring within 4-6 hours after administration.

Bioavailability: Approximately 60-70% after oral administration, with first-pass metabolism occurring in the liver.

Half-Life:

Oral: 14-26 hours

Intramuscular: 3-4 hours (initial) but can be prolonged due to depot formulations.

Metabolism: It is primarily metabolized in the liver by cytochrome P450 enzymes (mainly CYP3A4).

Excretion: Primarily excreted through the urine (40-60%) and bile (30-40%).

4. Indications

Schizophrenia (acute and chronic)

Acute Psychosis

Manic episodes of Bipolar Disorder

Tics and Vocal Utterances in Tourette Syndrome

Severe agitation or behavioral disorders

Nausea and vomiting (in certain cases)

5. Dosage and Administration

Oral:

Adults: 0.5 mg to 5 mg per day, adjusted based on clinical response. The usual dose range is 1-20 mg per day.

Elderly: Start at the lower end of the dosing range.

Intramuscular (IM): For acute agitation or psychosis, typically administered in doses of 2-5 mg. Repeated every 4-8 hours as necessary.

 

Additional Information:

• Port of Dispatch: INDIA
• Production Capacity: 20 MT
• Delivery Time: PROMPT
• Packaging Details: DRUM

Product Details:

We are offering high quality of Glimepiride powder. We are known for manufacturing, exporting, distributing, trading and supplying Glimepiride powder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Glimepiride powder in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Glimepiride powder

Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Glimepiride powder as well as Intermediates of Glimepiride powder.

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Shreeji Pharma International currently export Glimepiride powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Glimepiride is an oral medication primarily used to treat type 2 diabetes by helping to control blood sugar levels. It belongs to a class of drugs called sulfonylureas. Below are the key technical details of glimepiride:

1. Chemical Structure:

IUPAC Name: 1-[(4-{[3-ethyl-4-methyl-5-oxo-4,5-dihydro-1H-pyrrolo[3,4-b]quinolin-1-yl]carbonyl}phenyl)amino]sulfonyl]3-methyl-2-pyridinyl)methanone.

Molecular Formula: C24H34N2O5S

Molecular Weight: 490.6 g/mol

3. Dosage:

The starting dose is typically 1-2 mg per day, taken once a day, usually with breakfast or the first main meal.

The dosage may be adjusted based on blood glucose levels, with the maximum dose usually being 8 mg per day.

It is important to follow a healthcare provider’s instructions on dosing to avoid hypoglycemia (low blood sugar), which can occur if the dose is too high or if a meal is skipped.

4. Side Effects:

Common Side Effects:

Hypoglycemia (low blood sugar)

Nausea or upset stomach

Weight gain

Headache or dizziness

Serious Side Effects:

Severe hypoglycemia, which may lead to confusion, seizures, or loss of consciousness

Allergic reactions such as rash, itching, or swelling

Liver problems (rare)

5. Contraindications:

Glimepiride should not be used in people with:

Type 1 diabetes

Diabetic ketoacidosis

Severe liver or kidney impairment

Known hypersensitivity (allergy) to glimepiride or other sulfonylureas.

6. Drug Interactions:

Glimepiride can interact with other medications, including:

Other antidiabetic medications (increasing the risk of hypoglycemia)

Beta-blockers (which can mask symptoms of low blood sugar)

Corticosteroids (which may increase blood sugar levels)

Anticoagulants (blood thinners like warfarin, which may increase bleeding risk)

It’s important to inform a healthcare provider of all other medications being taken, including over-the-counter drugs and supplements.

7. Precautions:

Glimepiride should be used cautiously in people with:

Liver or kidney disease

A history of heart disease or stroke

Older adults (who may be more susceptible to side effects like hypoglycemia)

Regular blood sugar monitoring is crucial, especially at the beginning of treatment or when changing the dose.

8. Lifestyle Considerations:

 

Additional Information:

• Item Code: 93479-97-1
• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: INDIA
• Production Capacity: 1 MT
• Delivery Time: PROMPT
• Packaging Details: 25

Product Details:

We are offering high quality of Iodo Chloro Hydroxyquinoline. We are known for manufacturing, exporting, distributing, trading and supplying Iodo Chloro Hydroxyquinoline in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Iodo Chloro Hydroxyquinoline in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Iodo Chloro Hydroxyquinoline. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Iodo Chloro Hydroxyquinoline as well as Intermediates of Iodo Chloro Hydroxyquinoline is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Iodo Chloro Hydroxyquinoline to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries

Iodo Chloro Hydroxyquinoline, commonly known as Iodochloro Hydroxyquinoline, is a chemical compound that falls under the broader category of hydroxyquinolines, which are typically used as antiseptics, antibacterial agents, and fungicides. It combines elements of iodine (I), chlorine (Cl), and hydroxyl (OH) in a quinoline-based structure. Here's a breakdown of its technical details:

1. Chemical Formula:

The molecular formula for Iodo Chloro Hydroxyquinoline is:

C9H6ClINO

This indicates that the molecule consists of:

9 carbon (C) atoms

6 hydrogen (H) atoms

1 chlorine (Cl) atom

1 iodine (I) atom

1 oxygen (O) atom (from the hydroxyl group, OH)

2. Molecular Weight:

The molecular weight of Iodo Chloro Hydroxyquinoline is approximately 323.51 g/mol.

3. Chemical Structure:

Iodochloro Hydroxyquinoline has a structure based on quinoline, a bicyclic compound, with various functional groups attached. These include:

Hydroxy (-OH) at position 2 of the quinoline ring.

Chloro (-Cl) and Iodo (-I) substituents at positions 5 and 7, respectively, on the quinoline ring.

4. Physical Properties:

Appearance: It is typically a yellow to brown crystalline powder.

Solubility: It is usually sparingly soluble in water but dissolves well in organic solvents such as alcohol and chloroform.

Melting Point: The melting point of Iodochloro Hydroxyquinoline is around 168–170°C.

5. Applications:

Iodochloro Hydroxyquinoline is commonly used in a variety of industrial and medical applications, such as:

Antiseptic and antimicrobial: Used in medical formulations and as a disinfectant for wounds and skin infections.

Pharmaceutical: It may be included in some topical treatments due to its antibacterial and antifungal properties.

Chemical Synthesis: The compound may also serve as an intermediate in the synthesis of other chemicals.

6. Safety and Handling:

Precautions: As it contains halogenated groups (Cl and I), it is important to handle this compound with care, especially in concentrated forms.

Storage: Store in a cool, dry place away from sources of heat and direct sunlight. Keep in well-closed containers to prevent degradation.

 

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• Packaging Details: DRUM PACK

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We are offering high quality of Lidocaine Hydrochloride.We are known for manufacturing, exporting, distributing, trading and supplying Lidocaine Hydrochloride in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Lidocaine Hydrochloride in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Lidocaine Hydrochloride owadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Lidocaine Hydrochloride as well as Intermediates of Lidocaine Hydrochloride.Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Lidocaine Hydrochloride to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Technical specifications::

Synonyms:Lidocaine HCl / Lidocaine HCl hydrate / Lidocaine hydrochloride monohydrate

CAS Number : 6108-05-0

Weight : Average: 288.82

Monoisotopic: 288.1604558

Chemical Formula :C14H25ClN2O2

InChI Key: YECIFGHRMFEPJK-UHFFFAOYSA-N

Introduction:;Lidocaine, also known as lignocaine and sold under the brand name Xylocaine among others, is a local anesthetic of the amino amide type. It is also used to treat ventricular tachycardia. When used for local anaesthesia or in nerve blocks, lidocaine typically begins working within several minutes and lasts for half an hour to three hours. Lidocaine mixtures may also be applied directly to the skin or mucous membranes to numb the area.^[8] It is often used mixed with a small amount of adrenaline (epinephrine) to prolong its local effects and to decrease bleeding.Lidocaine has become an exceptionally commonly used medication  In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local anesthesia for a large variety of surgical procedures . It ultimately elicits its numbing activity by blocking sodium channels so that the neurons of local tissues that have the medication applied on are transiently incapable of signaling the brain regarding sensations In doing so, however, it can block or decrease muscle contractile, resulting in effects like vasodilation, hypotension, and irregular heart rate, among others As a result, lidocaine is also considered a class Ib anti-arrhythmic agent . Nevertheless, lidocaine's local anesthetic action sees its use in many medical situations or circumstances that may benefit from its action, including the treatment of premature ejaculation .

 

 Uses :

The efficacy profile of lidocaine as a local anaesthetic is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block, and surface anaesthesia. Longer-

Side effect:

Topical:Common side effects of topical lidocaine include irritation at site of application, including burning, blisters, bruising, redness, or swelling at the site of application. Lidocaine ointment, gel, and cream, as well as the oral solution, may also cause vomiting, seizures, ringing in the ears, and irregular heartbeat. Lidocaine ophthalmic gel may cause headache or bloodshot eyes.Lidocaine may also cause dizziness and drowsiness. 

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We are offering high quality of Clioquinol .We are known for manufacturing,exporting, distributing, trading and supplying Clioquinol in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

 Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Clioquinol in Gujarat, India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.

 Shreeji Pharma International is the largest manufacturer,Exporter and supplier of Clioquinol. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Clioquinol as well as Intermediates of Clioquinol.

 Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

 Shreeji Pharma International currently export Clioquinol to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Clioquinol is a synthetic antimicrobial compound that has historically been used for its antifungal and antibacterial properties. It was developed in the mid-20th century and has been used in the treatment of a variety of infections, particularly those affecting the skin and gastrointestinal tract. Here’s a more detailed description of Clioquinol:
Chemical Information:
IUPAC Name: 5-Chloro-7-iodo-8-hydroxyquinoline
Chemical Formula: C9H5ClINO
Molecular Weight: 305.50 g/mol
Structure: Clioquinol is derived from quinoline, with modifications such as chlorine (Cl) and iodine (I) atoms attached to the aromatic ring.
Mechanism of Action:
Clioquinol works by inhibiting the growth of microorganisms, primarily fungi and bacteria. It has been noted to disrupt the microbial membrane and inhibit various enzymes essential for microbial survival. Clioquinol also acts by binding to metals, particularly copper and zinc, which are crucial for the growth of many microorganisms.
Uses:
Clioquinol has been used in various forms for different medical conditions:
Topical Treatment: It has been commonly used as a topical agent for fungal skin infections, such as ringworm, and in the treatment of bacterial infections like impetigo.
Gastrointestinal Diseases: It has been used to treat infections in the gastrointestinal tract, such as traveler’s diarrhea and some types of dysentery.
Antifungal: In some formulations, it has been used as a broad-spectrum antifungal, effective against dermatophytes and yeasts.
Combination Therapy: It has also been combined with other compounds for enhanced therapeutic effects, such as in the treatment of some parasitic diseases.
Side Effects and Safety Concerns:
Neurotoxicity: Clioquinol has been associated with a rare but serious side effect known as subacute myelo-optic neuropathy (SMON), a condition that causes damage to the spinal cord and optic nerves. This condition became a significant safety concern, especially when Clioquinol was used in Japan during the 1970s, leading to its withdrawal from many markets.
Local Reactions: Topical use of Clioquinol can sometimes cause skin irritation, allergic reactions, or itching at the application site.
Systemic Toxicity: While rare, Clioquinol may lead to systemic toxicity when absorbed in larger quantities or with prolonged use.
Market Status:
In the past, Clioquinol was widely used, but due to safety concerns related to its neurotoxic effects, its use has become restricted or banned in several countries. 

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• Delivery Time: PROMPT

Product Details:

We are offering high quality of Metformin HCL We are known for manufacturing, exporting, distributing, trading and supplying Metformin HCL in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Metformin HCL in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Metformin HCL .Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Metformin HCL as well as Intermediates of Metformin HCL .Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Metformin HCL countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Metformin Hydrochloride (HCL) – Detailed Description

Overview:

Metformin Hydrochloride (HCL) is a widely used oral medication for the treatment of type 2 diabetes mellitus. It belongs to the biguanide class of drugs and helps control blood sugar levels by improving insulin sensitivity, reducing glucose production in the liver, and enhancing glucose uptake by muscles.

 

1. General Information

Brand Names: Glucophage, Glumetza, Riomet, Fortamet

Drug Class: Biguanide (Antidiabetic agent)

Available Forms: Tablets (Immediate-release & Extended-release), Oral Solution

Prescription Required: Yes

 

2. Mechanism of Action (How It Works)

Metformin primarily lowers blood sugar through three key mechanisms:

Decreasing Hepatic Glucose Production – Reduces the liver’s ability to produce glucose via gluconeogenesis.

Enhancing Insulin Sensitivity – Improves how the body’s cells respond to insulin, making them more efficient at absorbing glucose.

Reducing Intestinal Glucose Absorption – Slightly decreases the amount of glucose absorbed from food in the intestines.

Unlike some other diabetes medications, metformin does NOT cause insulin secretion, meaning it does not typically cause hypoglycemia (low blood sugar).

 

3. Uses & Indications

Primary Uses:

Type 2 Diabetes Mellitus – First-line treatment for blood sugar control.

Prediabetes (Off-label Use) – Sometimes prescribed to delay or prevent diabetes in high-risk individuals.

Other Off-Label Uses:

Polycystic Ovary Syndrome (PCOS) – Helps regulate menstrual cycles and improve insulin resistance.

Gestational Diabetes – Used in pregnancy as an alternative to insulin.

Weight Management (in Some Cases) – Aids in weight loss, especially in insulin-resistant individuals.

Non-Alcoholic Fatty Liver Disease (NAFLD) – Helps improve liver function in some cases.

 

4. Dosage & Administration

Standard Dosage for Type 2 Diabetes:

Immediate-Release Tablets:

Starting dose: 500 mg once or twice daily with meals.

Maintenance dose: 1,500–2,000 mg per day in divided doses.

Maximum dose: 2,550 mg/day.

 

 

 

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• Packaging Details: DRUM PACK

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We are offering high quality of Paroxetine HCL. We are known for manufacturing, exporting, distributing, trading and supplying Paroxetine HCL in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Paroxetine HCL in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

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Shreeji Pharma International currently exports Paroxetine HCL to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Paroxetine hydrochloride is the hydrochloride salt of paroxetine. It is an antidepressant drug. It has a role as an antidepressant, an anxiolytic drug, a hepatotoxic agent, a P450 inhibitor and a serotonin uptake inhibitor.

1. General Information: Chemical Name: Paroxetine Hydrochloride (HCl), Molecular Formula: C₁₉H₂₀FNO₃·HCl, Molecular Weight: 374.83 g/mol, IUPAC Name: (-)-trans-4R-(4'-fluorophenyl)-3S-[(3',4'-methylenedioxyphenoxy)methyl]piperidine hydrochloride, CAS Number: 78246-49-8

2. Physical & Chemical Properties: Appearance: White to off-white crystalline powder

Odor: Odorless or slightly characteristic odor

Solubility: Freely soluble in water, methanol, and ethanol; slightly soluble in chloroform; practically insoluble in acetone and ether, Melting Point: 120-138°C (varies with hydration state),Stability: Stable under normal conditions but sensitive to moisture and light

3. Pharmacological Classification: Drug Class: Selective Serotonin Reuptake Inhibitor (SSRI)

Therapeutic Use: Used to treat depression, anxiety disorders, panic disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD)

4. Mechanism of Action: Paroxetine HCl works by selectively inhibiting the reuptake of serotonin (5-HT) in the brain, increasing its availability at synaptic junctions, thereby enhancing mood regulation and reducing symptoms of anxiety and depression.

5. Applications: Pharmaceutical Use: Used as an active pharmaceutical ingredient (API) in formulations such as tablets, capsules, and oral suspensions.

Dosage Forms: Typically found in 10 mg, 20 mg, 30 mg, and 40 mg tablets or capsules.

6. Storage and Handling: Store in a cool, dry place at temperatures between 15°C and 30°C. Protect from light and moisture.

Shelf Life: Generally 2-3 years when stored properly.

Handling Precautions: Avoid inhalation and contact with skin or eyes. Use protective gear when handling in bulk.

7. Safety & Toxicity: Can be toxic in overdose, causing serotonin syndrome, seizures, and cardiovascular complications.

Side Effects: Common side effects include nausea, dizziness, drowsiness, dry mouth, sweating, and sexual dysfunction.

 

Contraindications: Should not be used with MAO inhibitors or in patients with a history of severe liver or kidney impairment without medical supervision.

Additional Information:

• Item Code: 96214003
• Port of Dispatch: India
• Production Capacity: 20MT
• Delivery Time: Prompt
• Packaging Details: 25 Kgs Drum Packing

Product Details:

We are offering high quality of Ondansetron Api Powder. We are known for manufacturing, exporting, distributing, trading and supplying Ondansetron Api Powder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

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Shreeji Pharma International currently exports Ondansetron Api Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Marking a niche in the medical sector, we are proficient in manufacturing and exporting a wide stock of Ondansetron Hydrochloride BP / USP. These are widely used during the chemotherapy and radiation therapy for cancer, in order to pevent vomiting and nausea. With excellent effects on the central and peripheral nerves, the offered Ondansetron Hydrochloride BP / USP is available to clients in different grades.

1. General Information: Name: Ondansetron

Chemical Name: 9-Methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4-one

Molecular Formula: C18H19N3O, Molecular Weight: 293.37 g/mol, CAS Number: 99614-02-5

Appearance: White to off-white crystalline powder

Solubility: Slightly soluble in water, freely soluble in methanol and dichloromethane

2. Pharmacological Classification: Category: Anti-emetic, Serotonin (5-HT3) Receptor Antagonist

Mechanism of Action: Ondansetron is a selective serotonin 5-HT3 receptor antagonist that blocks serotonin signals in the vagus nerve and the chemoreceptor trigger zone (CTZ) in the brain, thereby preventing nausea and vomiting.

3. Uses and Applications: Medical Use:

Prevention and treatment of nausea and vomiting caused by chemotherapy (CINV) and radiation therapy

Management of postoperative nausea and vomiting (PONV)

Treatment of nausea in other conditions (e.g., gastroenteritis, pregnancy-related nausea in certain cases)

Pharmaceutical Formulations: Tablets (Oral), Oral disintegrating tablets (ODT), Oral solution

Injectable form (IV, IM)

4. Physical and Chemical Properties: Melting Point: ~231-232°C, pH (in solution): 4.5–5.5, Log P (Partition Coefficient): ~2.1

5. Manufacturing and Quality Standards: Pharmacopoeial Standards: Complies with USP, BP, EP, and IP standards, Purity: ≥ 99% (HPLC)

Impurities and Residual Solvents: Residual solvents and heavy metals are controlled as per ICH guidelines, Storage Conditions: Store in a cool, dry place away from light and moisture, Keep in tightly sealed containers

6. Regulatory and Safety Information: Regulatory Approvals: Approved by FDA, EMA, and other global regulatory agencies

Toxicity and Side Effects: Generally well-tolerated, but may cause headaches, constipation, or dizziness

Rare but serious effects include QT prolongation and serotonin syndrome

Handling and Safety Precautions: Use gloves and protective gear when handling bulk powder

Avoid inhalation and direct skin contact,Dispose of according to local environmental regulations.

Additional Information:

• Item Code: 2933.29.90
• Delivery Time: immediate
• Packaging Details: drum pack

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We are offering high quality of Enoxaparin Sodium. We are known for manufacturing, exporting, distributing, trading and supplying Enoxaparin Sodium in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Enoxaparin Sodium  in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Enoxaparin Sodium  owadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Enoxaparin Sodium as well as Intermediates of Enoxaparin Sodium.
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Shreeji Pharma International currently export Enoxaparin Sodium  to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Enoxaparin Sodium Powder is a form of the injectable anticoagulant enoxaparin sodium, which is widely used for preventing and treating blood clots. It is a low molecular weight heparin (LMWH), a type of heparin that has been depolymerized to create a smaller molecule with improved pharmacological properties.
Here’s a detailed description of Enoxaparin Sodium Powder:
Chemical Name:
Enoxaparin Sodium.
Molecular Formula:
Enoxaparin sodium has a molecular formula that varies slightly depending on the specific preparation, but a common structure consists of polysaccharide chains with repeating disaccharide units.
Appearance:
Enoxaparin sodium is primarily used in the following conditions:
Deep Vein Thrombosis (DVT): To prevent and treat DVT, a condition where blood clots form in the deep veins, often in the legs.
Pulmonary Embolism (PE): To treat and prevent PE, which occurs when a blood clot breaks loose and travels to the lungs.
Unstable Angina and Non-Q-Wave Myocardial Infarction: Enoxaparin is used in certain cases of chest pain (angina) and heart attacks to prevent further clot formation.
Post-surgical Prophylaxis: To prevent the formation of clots after surgeries such as hip or knee replacement, or abdominal surgery.
Dosage: The dosage varies depending on the condition being treated. For example:
For DVT prevention, enoxaparin may be administered in doses of 40 mg once daily.
Side Effects:
Common side effects of enoxaparin sodium include:
Bleeding: As an anticoagulant, the most serious side effect is bleeding, which can occur in various parts of the body (e.g., gums, urine, or gastrointestinal tract).
Bruising at the injection site: Subcutaneous injections can cause localized bruising or irritation.
Precautions:
Renal Impairment: Enoxaparin is primarily excreted through the kidneys, so dose adjustments may be required for patients with kidney disease.
Pregnancy: Enoxaparin is classified as Category B in pregnancy, meaning it is generally considered safe, but should only be used when clearly needed. Close monitoring is necessary.

Storage:
Unreconstituted Powder: Enoxaparin sodium powder should be stored in a cool, dry place (generally at temperatures between 2°C and 8°C) and protected from light.
After Reconstitution: Once reconstituted, the solution should be used immediately or stored in the refrigerator (2°C to 8°C) for up to 24 hours, depending on the manufacturer’s instructions.
Packaging:
Enoxaparin sodium powder is typically packaged in vials or prefilled syringes for easy reconstitution and injection.

Additional Information:

• Production Capacity: 100 Kgs per Month
• Delivery Time: prompt
• Packaging Details: drum

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We are offering high quality of Calcium Lactobionate.We are known for manufacturing, exporting, distributing, trading and supplying Calcium Lactobionate  in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Calcium Lactobionate in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Calcium Lactobionate  owadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Calcium Lactobionate  as well as Intermediates of Calcium Lactobionate.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Calcium Lactobionate to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Calcium Lactobionate is a compound that is primarily used in pharmaceutical and cosmetic formulations. It is a calcium salt of lactobionic acid, which is derived from lactose (a type of sugar found in milk). Below are detailed descriptions of its uses and properties:
Chemical Structure

Calcium Lactobionate has the chemical formula C12H22CaO12. It consists of a calcium ion (Ca²⁺) complexed with lactobionic acid, which itself is a derivative of lactose.
Physical Properties
Appearance: It is typically a white to off-white powder or crystalline solid.
Solubility: It is water-soluble, which makes it easy to incorporate into aqueous solutions in pharmaceutical and cosmetic formulations.
Uses and Applications
Cosmetic Formulations:
Hydration: Calcium Lactobionate is often included in skin care products due to its ability to improve skin hydration.

Anti-Aging Effects: It is sometimes used in anti-aging formulations because it can help in the skin’s moisture retention and may have mild exfoliating effects.
Sensitive Skin: It is also used for products designed for sensitive skin, as it is typically gentle and can help soothe the skin.
Pharmaceutical Applications:
Calcium Supplementation: As a calcium salt, Calcium Lactobionate may be used in certain medical formulations as a calcium supplement, helping to treat or prevent calcium deficiencies. This is often done in the form of oral tablets or in intravenous solutions.
Bone Health: Due to its calcium content, it plays a role in promoting bone density and supporting overall bone health, particularly in people with osteoporosis or other conditions related to calcium deficiency.
Food Industry: While less common, Calcium Lactobionate can also be used as a food additive to fortify products with calcium, providing an additional source of this essential mineral.
Benefits
Bioavailability: The calcium in Calcium Lactobionate is considered to be well absorbed by the body, making it effective for supplementation purposes.
Gentle on Skin: In cosmetic products, it provides moisture and can help protect the skin without causing irritation, making it suitable for those with sensitive skin.
Mild Exfoliation: It can also act as a mild exfoliator, helping to remove dead skin cells and promote the growth of new, healthy skin cells.
Precautions
Allergic Reactions: As with any ingredient, there could be a possibility of allergic reactions, especially in individuals with sensitivities to dairy or lactose.

Additional Information:

• Production Capacity: 1000
• Delivery Time: Prompt
• Packaging Details: Packed in 25 Kgs HDPE Drums

Product Details:

Name: Quetiapine fumarate

CAS No.: 111974-72-2

Formula: C₄₆H₅₄N₆O₈S₂

Molecular Weight: 883.10

Synonyms: Ethanol,2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-,(2E)-2-butenedioate (2:1) (salt) (9CI);Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-,(E)-2-butenedioate (2:1) (salt);Dibenzo[b,f][1,4]thiazepine, ethanol deriv.;ICI 204636;Quetiapine hemifumarate;Seroquel;ZD 5077;ZM204636;

Melting Point: 174-176 °C

Boiling Point: 556.5 °C at 760 mmHg

Flash Point: 290.4 °C

Appearance: white crystalline solid

Quetiapine, sold under the brand name Seroquel among others, is an atypical antipsychotic medication used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. 

Molar mass: 383.5099 g/mol

CAS ID: 111974-69-7

Formula: C₂₁H₂₅N₃O₂S

Trade name: Seroquel, Temprolide, others

Elimination half-life: 7 hours (parent compound); 9–12 hours (active metabolite, norquetiapine)

Solubility in water: 3.29 mg/mL (20 °C)

People also search for: Sertraline, Olanzapine, Risperidone.

 

This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain.This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.

Additional Information:

• Item Code: 47335-906
• Delivery Time: Prompt
• Packaging Details: 25 Kg HDEP Drum