API

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We are offering high quality of Cefpodoxime Proxetil .We are known for manufacturing, exporting, distributing, trading and supplying Cefpodoxime Proxetil In Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Cefpodoxime Proxetil in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Cefpodoxime Proxetil  Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Cefpodoxime Proxetil as well as Intermediates of Cefpodoxime Proxetil.Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Cefpodoxime Proxetil to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Cefpodoxime is a third-generation cephalosporin antibiotic used to treat a wide range of bacterial infections. It works by inhibiting the synthesis of bacterial cell walls, ultimately leading to the destruction of the bacteria.
Here are some key details about Cefpodoxime:
1. Mechanism of Action:
Class: Cephalosporin (third-generation).
Cefpodoxime works by binding to specific proteins in bacterial cell walls, inhibiting the final stage of bacterial cell wall synthesis. This action results in bacterial cell lysis and death.
2. Spectrum of Activity:
Broad-spectrum activity: Effective against both Gram-positive and Gram-negative bacteria.
Common bacteria treated:
Gram-positive: Streptococcus pneumoniae, Staphylococcus aureus (including some methicillin-resistant strains).
Gram-negative: Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae, Moraxella catarrhalis.
It is typically less effective against some Gram-positive bacteria (like enterococci) compared to older cephalosporins.
3. Indications:
Cefpodoxime is used for various bacterial infections, including:
Respiratory infections: Pneumonia, bronchitis, tonsillitis, pharyngitis, and sinusitis.
Urinary tract infections (UTIs): Cystitis and pyelonephritis.
Skin and soft tissue infections.
Ear infections: Acute otitis media (middle ear infections).
4. Dosage and Administration:
Cefpodoxime is typically administered orally in the form of tablets or suspension.
Dosage depends on the type and severity of the infection, usually ranging from 100 mg to 400 mg per day, divided into two doses.
It is often taken with food to improve absorption.
5. Side Effects:
Common side effects include:
Gastrointestinal issues: Diarrhea, nausea, and abdominal pain.
Allergic reactions: Rash, itching, and in rare cases, severe allergic reactions (anaphylaxis).
Other effects: Headache, dizziness, and changes in liver enzyme levels.
Severe side effects are rare but can include:
Clostridium difficile-associated diarrhea (antibiotic-associated colitis).
Renal impairment: Caution is needed in patients with kidney issues.
6. Contraindications:
Allergy to cephalosporins: People with a known allergy to cephalosporins or penicillins should avoid using cefpodoxime.
Severe renal impairment: Dosage adjustments are needed for patients with impaired kidney function.
7. Drug Interactions:
Probenecid: Increases the blood levels of cefpodoxime by inhibiting its excretion.
Antacids or H2 blockers: 

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• Delivery Time: Immediate
• Packaging Details: 25 kg Drum Packing

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We are offering high quality of FAROPENAM SODIUM. We are known for manufacturing, exporting, distributing, trading and supplying FAROPENAM SODIUM in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of  FAROPENAM SODIUM in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of FAROPENAM SODIUM. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing FAROPENAM SODIUM as well as Intermediates of FAROPENAM SODIUM.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export FAROPENAM SODIUM to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries

Faropenem Sodium Powder is a form of faropenem, which is an antibiotic medication used to treat various bacterial infections. It is a broad-spectrum antibiotic belonging to the class of penem antibiotics, which are similar to penicillins but are more stable against certain types of bacterial enzymes that can degrade other antibiotics.
Here’s a more detailed description:

1. Active Ingredient:Faropenem Sodium is the sodium salt form of faropenem, a carbapenem-like antibiotic. It is effective against both gram-positive and gram-negative bacteria.

2. Mechanism of Action:Faropenem works by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs), disrupting the cell wall's structural integrity, leading to bacterial cell lysis and death.
3. Indications:Faropenem sodium is typically used for the treatment of infections caused by susceptible bacteria, including:

Respiratory tract infections: such as pneumonia, bronchitis, and sinusitis.

Urinary tract infections.

Skin and soft tissue infections.

Abdominal infections.

Gynecological infections.

4. Dosage Form

Faropenem Sodium Powder is typically provided as a powder for injection or intravenous infusion. The powder is reconstituted with sterile water or saline before administration.

After reconstitution, the solution is injected intravenously, and the dosage is adjusted based on the patient’s condition, weight, and infection severity.

5. Administration

The powder must be reconstituted and diluted before intravenous administration.

The typical dosage will vary depending on the infection being treated, and it is important to follow the prescribed regimen.

Intravenous use is the preferred method, especially for severe infections.

6. Side Effects

Common side effects can include:

Nausea, vomiting, or diarrhea.

Rash or allergic reactions.

In rare cases, more severe reactions such as liver toxicity or blood disorders may occur.

7. Contraindications and Precautions

Allergic reactions: Faropenem should be used with caution in patients who have a history of allergies to other beta-lactam antibiotics (e.g., penicillin, cephalosporins).

Pregnancy and Lactation: The safety of faropenem during pregnancy and breastfeeding is not well-established, so its use should be avoided unless clearly needed.

8. Storage

Faropenem sodium powder should be stored at room temperature, away from moisture and light.

 

Additional Information:

• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: india
• Production Capacity: 1 mt
• Delivery Time: prompt
• Packaging Details: drum

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We are offering high quality of Oxcarbazepine Api. We are known for manufacturing, exporting, distributing, trading and supplying Oxcarbazepine Api  in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Oxcarbazepine Api in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Oxcarbazepine Api. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Oxcarbazepine Api as well as Intermediates of Oxcarbazepine Api.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Oxcarbazepine Api to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

1. General Information-Chemical Name: Oxcarbazepine, CAS Number: 28721-07-5, Molecular Formula: C15H12N2O2, Molecular Weight: 252.27 g/mol, IUPAC Name: 10,11-Dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide, Synonyms: Trileptal, 10-Oxo-carbazepine

Therapeutic Category: Antiepileptic/Anticonvulsant

2. Physical & Chemical Properties: Appearance: White to off-white crystalline powder,             Odor: Odorless or nearly odorless, Melting Point: 215°C – 218°C, Solubility: Slightly soluble in water

pH: Neutral to slightly acidic in aqueous solution

Stability: Stable under normal conditions, but should be protected from moisture and light

3. Mechanism of Action: Oxcarbazepine is a prodrug that gets converted into 10-monohydroxy derivative (MHD), the active metabolite responsible for its pharmacological effects. It blocks voltage-gated sodium channels in neuronal membranes, reducing excitatory nerve impulses and stabilizing hyperexcitable neural membranes.

4. Applications & Uses:Treatment of partial seizures and generalized tonic-clonic seizures

Off-Label Uses: Bipolar disorder, neuropathic pain, and migraine prevention

Dosage Forms: Tablets, oral suspension, and extended-release formulations

5. Manufacturing & Quality Standards

Oxcarbazepine API must comply with various pharmacopoeial standards, including:

USP (United States Pharmacopeia), EP (European Pharmacopoeia), BP (British Pharmacopoeia)

IP (Indian Pharmacopoeia)

Key quality parameters include:

Assay (Purity): Typically ≥ 99.0% (HPLC)

Related Substances: Should be within specified limits (NMT 0.1% for any individual impurity)

Residual Solvents: Compliant with ICH Q3C guidelines, Loss on Drying (LOD): ≤ 0.5%

Heavy Metals: ≤ 10 ppm

6. Storage & Handling: Storage Conditions: Store in a cool, dry place at 25°C (77°F) with permitted excursions to 15°C-30°C (59°F-86°F)

Packaging: Usually packed in double polyethylene bags inside an aluminum drum

Shelf Life: Typically 2 to 3 years when stored under recommended conditions

7. Safety & Regulatory Considerations

Toxicity: Generally well-tolerated, but overdose may cause dizziness, drowsiness, nausea, and ataxia

Additional Information:

• Item Code: 5450-01-001
• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: India
• Production Capacity: 1 MT
• Delivery Time: Prompt
• Packaging Details: drum

Product Details:

We are offering high quality of Vardenafil. We are known for manufacturing, exporting, distributing, trading and supplying Vardenafil  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Vardenafil  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Vardenafil. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Vardenafil as well as Intermediates of Vardenafil.  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Vardenafil to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
 
Vardenafil is a medication primarily used to treat erectile dysfunction (ED), a condition in which a man is unable to achieve or maintain an erection sufficient for sexual activity. Vardenafil is part of a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors, which also includes other medications like sildenafil (Viagra) and tadalafil (Cialis). These drugs help increase blood flow to the penis, aiding in the ability to achieve an erection when sexually stimulated.
General Information:
Chemical Name: (RS)-1-[[3-(4-Bromophenyl)-1-propyl-1H-pyrazol-5-yl]methyl]-3-ethyl-4-(2-methoxyphenyl)-1H-pyrazole-5-carbaldehyde.
Molecular Formula: C23H22BrN3O3.
CAS Number: 224785-91-5.
Brand Names: Levitra, Staxyn (the orally disintegrating tablet form).
Drug Class: PDE5 inhibitor.
Uses:
Erectile Dysfunction (ED): The primary indication for vardenafil is the treatment of erectile dysfunction, including cases resulting from physical or psychological causes.
Off-label Uses:
Vardenafil may sometimes be prescribed off-label for pulmonary arterial hypertension (PAH), though this is not its primary FDA-approved use.
It may also be investigated for other cardiovascular conditions, but its primary use remains in the treatment of ED.
Side Effects:
Like all medications, vardenafil can cause side effects, although not everyone experiences them. Common side effects include:
Common Side Effects:
Headache (most frequent).
Flushing (feeling of warmth or redness).
Nasal congestion.
Dizziness or lightheadedness.
Indigestion (dyspepsia).
Back pain or muscle pain (rare).
Serious Side Effects (Less Common but Serious):
Precautions:
Cardiovascular Risk: Vardenafil should be used with caution in patients with underlying heart conditions, as it can cause low blood pressure (hypotension), especially when combined with nitrates (used for chest pain or heart conditions) or certain alpha-blockers (used for high blood pressure or prostate conditions). It is contraindicated in these situations.
Storage:
Store vardenafil tablets at room temperature, away from light and moisture.
Keep out of reach of children.
Do not use the medication past its expiration date.

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• Delivery Time: prompt
• Packaging Details: 25kgs drum pack

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• Item Code: 29280090
• Production Capacity: production capacity figures for niclosamide API powder are not readily available
• Delivery Time: prompt
• Packaging Details: 25kgs drum pack

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We are offering high quality of Papaverine Hcl. We are known for manufacturing, exporting, distributing, trading and supplying Papaverine Hcl in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Papaverine Hcl in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Papaverine Hcl. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Papaverine Hcl as well as Intermediates of Papaverine Hcl.   

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Papaverine Hcl to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

General Information: Chemical Name: Papaverine Hydrochloride, Molecular Formula: C₂₀H₂₂ClNO₄, Molecular Weight: 375.85 g/mol, CAS Number: 61-25-6, Appearance: White to off-white crystalline powder, Solubility: Freely soluble in water and alcohol

Properties and Uses: Pharmacological Class: Papaverine HCl is a vasodilator that primarily acts on smooth muscles, particularly in blood vessels, gastrointestinal, and genitourinary tracts.

Mechanism of Action: It inhibits phosphodiesterase (PDE) enzymes, leading to an increase in cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) levels.

This action promotes smooth muscle relaxation, improving blood flow and reducing spasms.

Medical Uses: Treatment of vasospasms: Used in conditions like cerebral and peripheral ischemia.

Erectile Dysfunction (ED): Often used in penile injections to induce vasodilation.

Gastrointestinal & Biliary Spasms: Helps in relieving spasmodic conditions in the GI tract.

Coronary Artery Disease: Occasionally used to improve blood flow in angina.

Industrial & Research Uses: Used in pharmaceutical research related to smooth muscle relaxants.

A component in compound injectable formulations for erectile dysfunction.

Dosage and Administration: Oral Tablets: 100-300 mg per day, divided into multiple doses.

Injectable Form: 30-120 mg via intramuscular (IM) or intravenous (IV) injection.

Topical Application: Sometimes used in compounded creams for circulation improvement.

Note: Dosage depends on the medical condition and should be prescribed by a healthcare professional.

Side Effects & Precautions: Flushing, Dizziness, Low blood pressure (hypotension), Nausea, Sweating

Serious Side Effects: Arrhythmias (irregular heartbeats), Liver dysfunction (rare)

Contraindications: Severe liver disease, Hypotension, Known hypersensitivity to papaverine

Drug Interactions: May enhance the effects of antihypertensive drugs.

Avoid combining with phosphodiesterase inhibitors (e.g., sildenafil) due to excessive vasodilation.

Interacts with anticoagulants, increasing the risk of bleeding.

Storage & Handling: Store in a cool, dry place away from moisture and direct sunlight.

Additional Information:

• Item Code: 51552-0416-4
• Delivery Time: prompt
• Packaging Details: 25 kg & 50 kg drum pack

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We are offering high quality of Cevimeline HCL. We are known for manufacturing,exporting,
distributing, trading and supplying Cevimeline HCL  in Gujarat, India. Further, this is safely
packaged by our professionals in diverse packaging options that maintain its purity and
effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplierof Cevimeline HCL in Gujarat. India. Shreeji Pharma International manufacturing & supplying allproducts under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplierof Cevimeline HCL Nowadays Shreeji Pharma International is one of the leading manufacturerand exporter, who is manufacturing Cevimeline HCL as well as Intermediates of Cevimeline HCL.Shreeji Pharma International is exporter, supplier, distributor and manufacturers of theActive Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Cevimeline HCL to countries like Gulf Countries,South East Asia countries, African Countries, CIS Countries, LATAMcountries, Centra American Countries and in European countriesCevimeline HCl is a medication commonly used to treat symptoms associated with dry mouth (xerostomia) in people with Sjögren's syndrome or who have undergone radiation therapy to the head and neck area. It is a cholinergic agonist that stimulates the muscarinic receptors in the salivary glands, promoting the secretion of saliva.Here are the key details about Cevimeline HCl:1. Mechanism of Action:Cevimeline is a muscarinic cholinergic receptor agonist, primarily targeting the M3 receptors found in the salivary glands. By stimulating these receptors, it increases saliva production and helps alleviate the dryness of the mouth that results from conditions like Sjögren's syndrome.2. Indications:Sjögren's syndrome: A condition where the immune system attacks moisture-producing glands, resulting in dry mouth and dry eyes.Radiation-induced dry mouth: Patients undergoing radiation therapy, especially to the head and neck, may develop xerostomia due to damage to the salivary glands.3. Dosage and Administration:The typical dose of Cevimeline HCl for adults is 30 mg three times daily. The dosage may vary depending on the severity of the condition and the physician's recommendation.4. Side Effects:Like other cholinergic medications, Cevimeline can have a range of side effects, including
Sweating
Nausea
DiarrheaFlushing
Increased salivation
Headache
Blurred vision
Dizziness
These side effects occur because of the systemic cholinergic effects, and not everyone experiences them. However, if they occur, they can be bothersome and may require a dosage adjustment or discontinuation of the drug.
5. Contraindications:
Cevimeline should be used cautiously or avoided in patients with:
Severe asthma or other respiratory conditions
Glaucoma (particularly narrow-angle glaucoma)
Heart conditions, especially arrhythmias or other severe cardiac diseases, as it can increase vagal tone and affect heart rate
Liver disease: The drug should be used with caution, and dose adjustments may be needed.
6. Warnings and Precautions:
Hydration: It is important for patients to stay hydrated, as Cevimeline may cause excessive sweating and dehydration.
Caution in elderly: Older adults may be more sensitive to side effects, including gastrointestinal disturbances, dizziness, and heart issues.
Monitor for potential cardiovascular effects: Since it may influence heart rate and rhythm, patients with a history of cardiovascular disease should be closely monitored.
7. Drug Interactions:
Cevimeline may interact with other medications, especially those that affect acetylcholine levels or have anticholinergic effects. 

 

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• Production Capacity: 1000
• Delivery Time: immediate
• Packaging Details: 25 kg drum pack

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We are offering high quality of Cilostazol. We are known for manufacturing,exporting,distributing, trading and supplying Cilostazol  in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Cilostazol in Gujarat. India. Shreeji Pharma International manufacturing & supplying all
products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Cilostazol. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Cilostazol  as well as Intermediates of Cilostazol.Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Cilostazol to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries
Cilostazol is a medication primarily used to treat intermittent claudication, a condition characterized by leg pain or cramping due to poor circulation, often caused by peripheral artery disease (PAD). It works by improving blood flow to the legs and reducing symptoms such as pain, cramping, and weakness that occur with physical activity.
Mechanism of Action:
Cilostazol is a phosphodiesterase III inhibitor. It works by:

• Inhibiting the enzyme phosphodiesterase type 3 (PDE3), which leads to an increase in cyclic AMP (cAMP) within platelets and smooth muscle cells.
• This increase in cAMP causes vasodilation (widening of blood vessels) and inhibits platelet aggregation, which improves blood flow and reduces the risk of blood clots.
• It also has antiplatelet effects, making it useful in reducing the risk of blood clot formation in certain conditions.
• Primary Uses:

1. Intermittent Claudication: Cilostazol is most commonly used for managing intermittent claudication associated with peripheral artery disease (PAD). By improving blood flow to the muscles of the legs, it helps reduce pain and discomfort during walking or exercise.
2. Stroke Prevention: In some cases, it may be used off-label to reduce the risk of stroke in patients with a history of transient ischemic attacks (TIAs) or stroke, due to its antiplatelet properties.

Dosage and Administration:

• The typical dose of cilostazol is 100 mg twice daily, taken on an empty stomach (at least 30 minutes before or 2 hours after a meal).
• Dosage may need adjustment for patients with renal impairment or those on other medications that interact with cilostazol.

Side Effects:

While cilostazol is generally well-tolerated, it can cause side effects, such as:

• Headache: One of the most common side effects.
• Diarrhea or gastrointestinal discomfort.
• Palpitations or rapid heartbeat.
• Dizziness or lightheadedness.
• Edema (swelling), particularly in the lower legs.
• Nausea.

Warnings and Precautions:

• Heart Failure: Cilostazol is contraindicated in patients with heart failure, especially those with severe heart failure, as it can worsen symptoms.
• Bleeding Risk: Cilostazol can increase the risk of bleeding, particularly when used in conjunction with other blood thinners or antiplatelet drugs.
• Liver and Kidney Function: Cilostazol should be used with caution in patients with liver or kidney impairments, and dose adjustments may be necessary.

 

 

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• Delivery Time: immediate
• Packaging Details: 25 kg drum pack

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We are offering high quality of Fluazuron Powder Api. We are known for manufacturing, exporting, distributing, trading and supplying Fluazuron Powder Api in maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Fluazuron Powder Api in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Fluazuron Powder Api .  Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Fluazuron Powder Api as well as Intermediates of Fluazuron Powder Api.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Fluazuron Powder Api to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Fluazuron is a chemical compound that belongs to the class of insecticides and acaricides (pesticides targeting arthropods like insects and mites). It is primarily used in agricultural and veterinary applications to control a range of pests, including ticks and fleas. It is also used to manage pest infestations in livestock, especially in cattle and sheep. Below is a detailed description of Fluazuron:

Chemical Structure and Properties

Chemical name: 1-(2,6-Difluorophenyl)-3-(4-(trifluoromethyl)phenyl)-1H-pyrazole-5-carbaldehyde

Molecular formula: C16H10F5N3O

Physical state: It is usually found in the form of a crystalline solid or as a powder.

Solubility: Fluazuron is typically insoluble in water but soluble in organic solvents like acetone or dichloromethane.

Chemical Formula: C14H8Cl2FN3O

CAS Number: 86687-13-2

Mode of Action:
Fluazuron works by inhibiting the synthesis of chitin, a key component in the exoskeletons of insects and arachnids. By interfering with chitin biosynthesis, it disrupts the development of these organisms, particularly affecting the molting process. This leads to their death or inability to mature.

Target Organisms:
It is effective against various pests, including:

Ticks (e.g., Ixodes species, Rhipicephalus species)

Mites and other arthropods

Some insect pests in crops, such as lepidopteran larvae

Applications:

Agriculture: It is used to protect crops from certain pests, including those that affect cotton, cereals, vegetables, and fruits.

Veterinary Medicine: Fluazuron is commonly used in the form of pour-on treatments for livestock to control tick infestations (e.g., in cattle) and other ectoparasites.

Tick Control: In veterinary applications, it is used to prevent tick-borne diseases like babesiosis and anaplasmosis in cattle and other livestock.

Environmental Impact:
Fluazuron is generally considered to have a low environmental toxicity, but as with all pesticides, careful management is necessary to avoid resistance buildup and non-target species impact. It is moderately persistent in the environment, with its half-life varying based on soil and environmental conditions.

Safety and Toxicity:

Human Toxicity: Fluazuron has low acute toxicity in humans, but it is recommended to handle it with care and avoid inhalation or ingestion.

Ecotoxicology: Low toxicity to birds and mammals, but more research is needed to evaluate effects on aquatic organisms.

Additional Information:

• Delivery Time: immediate
• Packaging Details: HDPE DRUM PACK

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We are offering high quality of Toldimfos sodium . We are known for manufacturing, exporting, distributing, trading and supplying Toldimfos sodium   in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Toldimfos sodium   in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Toldimfos sodium . Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Toldimfos sodium  as well as Intermediates of Toldimfos sodium .  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Toldimfos sodium  to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Toldimfos Sodium is a phosphodiesterase (PDE) inhibitor that is used primarily in the treatment of chronic obstructive pulmonary disease (COPD) and other pulmonary diseases, particularly for managing symptoms of bronchospasm. It acts by increasing the levels of cyclic adenosine monophosphate (cAMP) within smooth muscle cells, which leads to bronchodilation (widening of the airways), helping improve airflow in the lungs.
Description & Properties:
Chemical Name: Sodium 3-[2-(2,4-dimethylphenyl)-1,3-thiazol-4-yl]-1,3,5-triazine-2,4-diamine
Chemical Formula: C11H14N4S•Na
Molecular Weight: 266.32 g/mol
Appearance: White to off-white powder.
Solubility: Soluble in water.
Toldimfos Sodium is typically available in oral tablet or powder form for inhalation.
Mechanism of Action:
Toldimfos Sodium works by inhibiting phosphodiesterase type 4 (PDE4), an enzyme that degrades cyclic adenosine monophosphate (cAMP) in cells. By inhibiting PDE4, Toldimfos increases the levels of cAMP within cells, leading to bronchodilation and reduced inflammation in the airways. This results in eased breathing and decreased symptoms of bronchospasm, a condition where the airways tighten and narrow.
PDE4 Inhibition: By inhibiting PDE4, Toldimfos also reduces the release of inflammatory mediators, improving lung function and reducing airway inflammation.
Uses:Toldimfos Sodium is primarily used in the management of conditions involving bronchospasm and airway inflammation. Its main uses include:
Dosage and Administration:
The dosage of Toldimfos Sodium will vary depending on the condition being treated and the individual patient. It is important to follow the instructions provided by the healthcare provider.
Side Effects:
Toldimfos Sodium can cause a variety of side effects, some of which may be serious. Common and severe side effects include:
Gastrointestinal: Nausea, vomiting, and diarrhea may occur in some patients.
Headache: A common side effect when taking the medication.
Dizziness or lightheadedness.
Fatigue or weakness.
Liver Disease: Toldimfos Sodium should be used with caution in patients with liver dysfunction. Liver function should be monitored during treatment.
Storage:Storage Conditions: Store at room temperature (20–25°C or 68–77°F), away from heat, moisture, and light

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• Delivery Time: immediate
• Packaging Details: HDPE DRUM PACK

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We are offering high quality of Oxetacaine. We are known for manufacturing,exporting, distributing, trading and supplying Oxetacaine in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Oxetacaine in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.

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Shreeji Pharma International currently export Oxetacaine to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central

American Countries and in European countries

Chemical Name: 2,2'-(2-hydroxyethylimino)bis[N-(1,1-dimethyl-2-phenylethyl)-N-methylacetamide]
Common Name: Oxetacaine (also spelled Oxethazaine)
CAS Number: 126-27-2
Molecular Formula: C28H41N3O3
Molecular Weight: 467.64 g/mol
Appearance: White to off-white crystalline powder
Solubility: Practically insoluble in water; soluble in ethanol, chloroform, and other organic solvents
Storage Conditions: Store in a tightly closed container, protected from light and moisture, at room temperature (20–25°C)

Pharmacological Classification:

Class: Potent local anesthetic

Therapeutic Use: Gastrointestinal topical anesthetic

Mechanism of Action:

Oxetacaine works by blocking sodium channels in neuronal cell membranes, which inhibits nerve signal conduction. It is uniquely effective in acidic environments, making it ideal for use in conditions like gastritis and ulcers.

Applications:

Used in combination with antacids (like aluminum hydroxide, magnesium hydroxide, and simethicone) in oral suspensions to treat:Gastric ulcers,Esophagitis,Gastritis,Heartburn

Reduces pain and discomfort associated with acid-related gastrointestinal conditions

Key Properties:

Stability in acidic pH (unlike most local anesthetics)

Rapid onset of local anesthetic action in the stomach lining

Provides topical pain relief without systemic anesthesia

Side Effects:

Rare when used topically in recommended doses

Nausea, allergic reactions (rash, itching)

Very rarely: Methemoglobinemia (especially in overdoses)

Precautions & Warnings:

Not recommended for long-term use without medical supervision

Use with caution in patients with liver impairment

Should not be used in children or infants without pediatric advice

Avoid combining with other local anesthetics unless advised by a physician

Evaluate risk in pregnancy and lactation

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• Delivery Time: immediate
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We are offering high quality of Molnupiravir.We are known for manufacturing, exporting, distributing, trading and supplying Molnupiravir in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Molnupiravir in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of  Molnupiravir. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing . Molnupiravir as well as Intermediates of  Molnupiravir. Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Molnupiravir countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries. 

Molnupiravir API Powder – Description & Details

Chemical Name: Molnupiravir
CAS Number: 2349386-89-4
Molecular Formula: C₁₃H₁₉N₃O₇
Molecular Weight: 329.31 g/mol

General Description:

Molnupiravir is an antiviral drug primarily developed for the treatment of COVID-19. It is an oral prodrug of N4-hydroxycytidine (EIDD-1931), which inhibits viral replication by inducing RNA mutagenesis in SARS-CoV-2. The active pharmaceutical ingredient (API) is used in the production of Molnupiravir capsules for therapeutic use.

Physical & Chemical Properties:

Appearance: White to off-white crystalline powder

Solubility: Soluble in DMSO, slightly soluble in water

Purity: ≥ 99% (as per HPLC analysis)

Melting Point: ~158-163°C

Storage Conditions: Store at 2-8°C in a dry, dark, and ventilated place

Mechanism of Action:

Molnupiravir is metabolized into its active form, N4-hydroxycytidine (EIDD-1931), inside the body. This active form incorporates into viral RNA and induces excessive mutations, leading to the "error catastrophe," preventing the virus from replicating efficiently.

Applications:

Used for the synthesis of Molnupiravir capsules

Research and development of antiviral medications

Inhibitor for SARS-CoV-2 and related RNA viruses

Physical & Chemical                       Details

Appearance                      White to off-white crystalline powder

Solubility                        Slightly soluble in water, soluble in DMSO

Purity                                ≥ 99% (by HPLC)

Melting Point                 ~158-163°C    

 Storage                            Store at 2-8°C, in a dry, ventilated place away from light

 

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• Item Code: 00006505507
• Production Capacity: 1 MT
• Delivery Time: Prompt
• Packaging Details: Drum

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We are offering high quality of Fluconazole Api Powder. We are known for manufacturing, exporting, distributing, trading and supplying Fluconazole Api Powder in maintain its purity and effectiveness.

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1. Chemical Information

IUPAC Name: 1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-3-(1H-1,2,4-triazol-1-yl)propane-2-ol

Molecular Formula: C13H12F2N6O

Molecular Weight: 306.27 g/mol

CAS Number: 86386-73-4

Melting Point: 141-145°C (depends on the polymorph)

Solubility:

Water: Slightly soluble in water (10–50 mg/L)

Solvents: Soluble in organic solvents like ethanol, methanol, and dimethyl sulfoxide (DMSO).

Fluconazole is an antifungal medication used to treat a variety of fungal infections. It works by inhibiting the growth of fungi, specifically by interfering with the synthesis of ergosterol, a key component of fungal cell membranes. This disruption weakens the fungal cell membrane, leading to the death of the fungus.

Common Uses:

Candida Infections: Fluconazole is often prescribed to treat yeast infections, such as:

Vaginal candidiasis (yeast infections)

Oral thrush

Esophageal candidiasis

Invasive candidiasis

Prevention: In patients with weakened immune systems, such as those undergoing chemotherapy or bone marrow transplants, fluconazole may be used to prevent fungal infections.

Forms and Dosage:

Fluconazole is available in several forms:

Oral: Tablets or oral suspension

Intravenous (IV): For more severe infections or when oral administration is not possible.

The dosage depends on the type and severity of the infection and the patient's individual health factors. Common starting doses for adults may range from 50 mg to 400 mg per day, depending on the infection being treated.

Side Effects:

Some common side effects include:

Nausea

Headache

Abdominal pain

Dizziness

Rash

More serious side effects, though rare, include liver damage, severe allergic reactions, and heart arrhythmias. Patients with a history of liver disease or prolonged use of the drug may need closer monitoring.

Contraindications:

Fluconazole should not be used by people who have an allergy to fluconazole or similar antifungal medications (such as itraconazole or ketoconazole).

It may interact with other medications, particularly those that affect the liver, and should be used cautiously in individuals on medications that prolong the QT interval (a measure of heart rhythm).

 

 

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• Delivery Time: PROMPT
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We are offering high quality of Ropivacaine. We are known for manufacturing, exporting, distributing, trading and supplying Ropivacaine  in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Ropivacaine  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Ropivacaine. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Ropivacaine as well as Intermediates of Ropivacaine.  Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Ropivacaine to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

General Information:Ropivacaine is a long-acting local anesthetic belonging to the amino amide class. It is primarily used for regional anesthesia, epidural anesthesia, and nerve block procedures in surgery, labor pain management, and postoperative pain relief. Compared to bupivacaine, it has a lower risk of cardiotoxicity and reduced central nervous system (CNS) toxicity.Chemical Properties:Chemical Name: (S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamideMolecular Formula: C₁₇H₂₆N₂OMolecular Weight: 274.4 g/mol CAS Number: 84057-95-4Appearance: White crystalline powder Solubility: Freely soluble in water and ethanolMelting Point: ~142–146°C  pKa: ~8.1Stability: Stable under normal conditions, sensitive to extreme pHMechanism of Action: Blocks sodium ion channels in nerve cells, preventing depolarization and conduction of nerve impulses.Produces sensory and motor blockade, leading to pain relief and loss of sensation.Has a lower motor blockade effect compared to bupivacaine, making it preferable for labor and postoperative pain management.Pharmacokinetics:Onset: 10–30 minutes, depending on the route and concentration.Duration: 2–6 hours (varies based on dose and site of administration).Metabolism: Primarily metabolized in the liver (CYP1A2 enzyme).Half-life: 1.5–6 hours (dose-dependent).Excretion: Mainly via urine as metabolites.Therapeutic Uses & Applications:Epidural anesthesia for labor and postoperative pain.Peripheral nerve blocks for surgical procedures (upper/lower limb surgeries).Infiltration anesthesia (wound infiltration for post-surgical pain relief).Continuous nerve block infusions in pain management settings.Dosage & Administration:Epidural Block (Labor or Surgery):Initial dose: 10–20 mL of 0.2%–0.75% solution.Continuous infusion: 6–14 mL/hour of 0.2% solution.Peripheral Nerve Block:Single dose: 10–40 mL of 0.5% solution.Continuous infusion: 5–10 mL/hour of 0.2% solution.Infiltration Anesthesia:Up to 200 mg (e.g., 20 mL of 1% solution).Side EffectsHypotensionNauseaDizzinessSerious (Rare):Local anesthetic systemic toxicity (LAST) (seizures, cardiac arrest in high doses)BradycardiaRespiratory depressionPatients with severe liver dysfunction.Known hypersensitivity to amide-type local anesthetics.Use with caution in:Elderly patients 

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We are offering high quality of Benzocaine. We are known for manufacturing, exporting, distributing, trading and supplying Benzocaine in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Benzocaine in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
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Shreeji Pharma International currently export Benzocaine to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Benzocaine is a local anesthetic often used in topical applications for pain relief. Here is the technical data and description of Benzocaine powder:

Chemical Name: Ethyl 4-aminobenzoate
Synonyms: Ethyl p-aminobenzoate, Aethyl-p-aminobenzoate, Anaesthesin
CAS Number: 94-09-7
Molecular Formula: C9H11NO2
Molecular Weight: 165.19 g/mol
Chemical Name: Ethyl 4-aminobenzoate
Description:Benzocaine is a white, crystalline powder with a slightly bitter taste. It is commonly used as a topical analgesic in various formulations, including creams, ointments, and gels. It provides local relief from pain and discomfort caused by conditions like sunburn, insect bites, sore throats, and minor skin irritations.
Physical Appearance: White to off-white crystalline powder
Solubility: Slightly soluble in water; soluble in alcohol and chloroform
Melting Point: 88–90°C
Boiling Point: Decomposes before boiling (approximately 297°C)
Density: 1.17 g/cm³
Odor: Slight characteristic odor
Taste: Slightly bitter
Uses and Applications
Topical Anesthetic: It is used in topical formulations such as ointments, gels, and creams for relieving pain or itching from minor burns, insect stings, and other skin conditions.
Oral Care: Found in some throat lozenges and sprays for numbing the throat to relieve pain caused by minor sore throats.
Dental Anesthesia: In some over-the-counter oral gels for numbing the gums and oral cavity before dental procedures.
First Aid: Used in products like sunburn relief lotions or insect bite creams for localized pain relief
Water: Slightly soluble in water (about 0.03% at 25°C).
Organic Solvents: Soluble in alcohol, chloroform, and ether.
Ethanol: Soluble.
Other Solvents: Slightly soluble in propylene glycol.
Density: 1.17 g/cm³
Refractive Index: ~1.555 at 20°C.
pH: Benzocaine is a weak base. It does not have a specific pH value but can be dissolved in a suitable solvent like ethanol.
Uses and Applications:Benzocaine is widely used in both medical and cosmetic products due to its numbing properties.
Topical Anesthetic: Primarily used in topical applications such as gels, ointments, and creams to relieve pain and discomfort caused by conditions like insect bites, burns, sore throats, and minor cuts.
Oral Care: Found in some throat lozenges, sprays, or gels to relieve pain from sore throats or gum irritation.

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Ractopamine hydrochloride is a feed additive used in livestock to promote leanness and enhance feed efficiency. It functions as an agonist to β1 and β2 adrenergic receptors, leading to increased protein synthesis and muscle fiber growth.

Chemical Information:
Chemical Name: 4- {3- [2-Hydroxy-2- (4-hydroxyphenyl)ethyl]aminobutylphenol hydrochloride
Molecular Formula: C₁₈H₂₃NO₃·HCl
Molecular Weight: 337.84 g/mol
CAS Number: 90274-24-1

Applications:Ractopamine hydrochloride is primarily used in the livestock industry to promote lean muscle growth and improve feed conversion efficiency. It is the active ingredient in products such as Paylean for swine, Optaflexx for cattle, and Topmax for turkeys.

Side Effects in Animals:

Behavioral and Physical Effects: In swine, ractopamine has been associated with increased hyperactivity, trembling, and a higher incidence of broken limbs. These adverse effects have led to criticism from animal welfare organizations. Similarly, in cattle, ractopamine use has been linked to stiffness, sore limbs, lameness, and increased susceptibility to heat stress.

Potential Human Health Concerns:

Cardiovascular Effects: Studies have shown that ractopamine can cause dose-dependent cardiovascular changes in humans. At higher doses, individuals experienced elevated heart rates, increased cardiac output, and higher systolic blood pressure.

Other Adverse Effects: Consumption of ractopamine residues in meat may lead to symptoms such as tremors, headaches, muscle spasms, and elevated arterial blood pressure.

Precautions and Regulatory Guidelines:

Acceptable Daily Intake (ADI): The Joint FAO/WHO Expert Committee on Food Additives (JECFA) has established an ADI for ractopamine at 0–1 µg per kilogram of body weight per day. This recommendation is based on observed no-effect levels and incorporates safety factors to protect sensitive individuals.

Maximum Residue Limits (MRLs): JECFA has set MRLs for ractopamine residues in various animal tissues:

Muscle and Fat (Cattle and Pigs): 10 µg/kg

Liver (Cattle and Pigs): 40 µg/kg

Kidney (Cattle and Pigs): 90 µg/kg

These limits aim to ensure that meat products derived from animals treated with ractopamine are safe for human consumption.

Availability:Ractopamine hydrochloride is available from various suppliers, including SynZeal, which provides the compound accompanied by a Certificate of Analysis.

We are offering high quality of Ractopamine Hcl. We are known for manufacturing, exporting, distributing, trading and supplying Ractopamine Hcl in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

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We are offering high quality of Dibenzo[b,f][1,4]thiazepin-11(10H)-one We are known for manufacturing, exporting,distributing, trading and supplying Digoxin in Gujarat, India. Further, this is safelypackaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Dibenzo[b,f][1,4]thiazepin-11(10H)-one in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Dibenzo[b,f][1,4]thiazepin-11(10H)-one Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Quetiapine Fumarate as well as Intermediates of Dibenzo[b,f][1,4]thiazepin-11(10H)-one .Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Dibenzo[b,f][1,4]thiazepin-11(10H)-one to countries like Gulf Countries,South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries.
Dibenzo-thiazepine is a chemical compound that belongs to the thiazepine class of organic compounds, which are characterized by a seven-membered ring containing both sulfur and nitrogen atoms. It is a fused ring structure containing a benzene ring (a six-membered carbon ring) and a thiazepine ring (a seven-membered ring with sulfur and nitrogen atoms).However, the term "Dibenzo Thiazepine" is somewhat general, and variations of the compound might exist depending on the specific position of the substituents or the chemical formulation. Below is an overview of this class of compounds based on the general structure:Chemical Structure and PropertiesIUPAC Name: The name depends on the specific structure. A common one would be Dibenzo[b,d]thiazepine, which indicates the compound is a thiazepine fused to two benzene rings.
Molecular Formula: C15H11NS
Molecular Weight: 223.32 g/molStructure: The compound consists of a seven-membered thiazepine ring fused to two benzene rings. The thiazepine ring contains one sulfur atom and one nitrogen atom.Physical PropertiesAppearance: Typically, it can appear as a white to off-white powder. The specific form or purity may vary depending on the grade.
Solubility: Soluble in organic solvents like chloroform or acetone but usually insoluble in water.
Uses
Dibenzo-thiazepine and its derivatives may have various uses depending on their specific chemical properties and structure. Some known uses include:
Pharmaceuticals:
The thiazepine ring is a common structure in pharmaceutical chemistry, especially for compounds with anti-anxiety, antidepressant, or antipsychotic effects. While Dibenzo-thiazepine itself may not be directly used in these applications, related structures, such as clozapine (an antipsychotic), derive from this family of compounds.
Organic Synthesis:
Dibenzo-thiazepines can be used as intermediates or building blocks in the synthesis of more complex compounds. The thiazepine core can act as a scaffold for creating molecules with various biological or chemical activities.
Material Science:
As part of the larger class of heterocyclic compounds, Dibenzo-thiazepine derivatives can be used in specialized materials or polymer development due to their unique molecular structures.
Safety and Toxicology
The safety and toxicity profile of Dibenzo-thiazepine and its derivatives would depend on the specific compound. Clozapine, for example, while effective for certain conditions, has notable side effects such as sedation, weight gain, and the potential for more severe adverse effects like agranulocytosis 

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We are offering high quality of Paracetamol Powder Ip. We are known for manufacturing, exporting, distributing, trading and supplying Paracetamol Powder Ip in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

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1. Introduction: Paracetamol Powder IP (Indian Pharmacopoeia) is a widely used analgesic (pain reliever) and antipyretic (fever reducer). It is a pharmaceutical-grade raw material used in various formulations like tablets, syrups, suspensions, and injections.

2. Chemical and Physical Properties: Chemical Name: N-(4-Hydroxyphenyl)acetamide, Molecular Formula: C₈H₉NO₂, Molecular Weight: 151.16 g/mol, CAS Number: 103-90-2, Appearance: White crystalline powder, Odor: Odorless, Melting Point: 168–172°C, pH (Solution in Water): Neutral to slightly acidic

3. Pharmacological Properties: Mechanism of Action: Inhibits the enzyme cyclooxygenase (COX) in the brain, reducing prostaglandin synthesis, Unlike NSAIDs, it has minimal anti-inflammatory effects,

4. Uses and Applications: Medical Uses: Relief from mild to moderate pain (e.g., headaches, muscle aches, arthritis), Reduction of fever, Often used in combination with other drugs like caffeine or codeine

Pharmaceutical Formulations: Tablets (e.g., 500 mg, 650 mg), Capsules, Syrups and suspensions (for pediatric use), Injectables (IV formulations), Topical gels (in combination with other analgesics)

Industrial Uses: Used in veterinary medicine, Incorporated in some cosmetic formulations

5. Dosage and Administration: Adults: 500 mg to 1 g every 4-6 hours (Max: 4 g/day), Children (6-12 years): 250-500 mg every 4-6 hours, Infants (Under 6 years): Given in syrup/suspension form as per doctor’s recommendation.

 6. Side Effects and Precautions: Common Side Effects: Nausea, Vomiting, Mild stomach upset

Serious Side Effects (Rare): Liver toxicity (in overdose cases), Allergic reactions (rash, swelling), Kidney damage (in prolonged high doses)

7. Storage and Stability: Store in a cool, dry place (below 25°C), Keep away from moisture and direct sunlight, Keep in tightly closed containers, Shelf Life: Typically 3-5 years

8. Regulatory Compliance: Complies with quality and purity specifications set by IP

Used in pharmaceutical formulations adhering to regulatory norms

Conclusion: Paracetamol Powder IP is an essential pharmaceutical raw material with analgesic and antipyretic properties. It is widely used in various dosage forms for fever and pain relief. Proper usage and dosage adherence are crucial to avoid side effects, particularly liver toxicity.

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We are offering high quality of CLOXACILLIN SODIUM . We are known for manufacturing, exporting, distributing, trading and supplying CLOXACILLIN SODIUM   in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
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Cloxacillin Sodium is a type of antibiotic belonging to the class of penicillins. It is used to treat bacterial infections, particularly those caused by penicillinase-producing organisms, such as Staphylococcus aureus. This makes it effective against infections that are resistant to other penicillins, including methicillin-resistant Staphylococcus aureus (MRSA).Chemical Structure and Properties:
Molecular Formula: C19H17Cl2N3NaO5S
Appearance: White or almost white, crystalline powder
Solubility: Cloxacillin sodium is soluble in water and alcohol. It is typically available in both oral and intravenous formulations.
Side Effects:While generally well-tolerated, cloxacillin sodium may cause some side effects, such as:
Gastrointestinal issues: Nausea, vomiting, diarrhea
Allergic reactions: Rash, itching, anaphylaxis (rare but serious)
Hepatic effects: Elevation of liver enzymes or liver damage (rare)
Renal effects: Rarely, it can affect kidney function, especially when used in high doses or for extended periods.
Hematologic effects: Leukopenia (low white blood cell count) or thrombocytopenia (low platelet count) may occur in some cases.
Precautions and Contraindications:
Allergy to penicillin or cephalosporins: Patients who have a history of hypersensitivity to penicillin or cephalosporin antibiotics should avoid using cloxacillin.
Pregnancy and lactation: Cloxacillin is categorized as Category B by the FDA, meaning it has not shown teratogenic effects in animal studies, but its safety in pregnancy has not been fully established. It should be used during pregnancy only if clearly needed and prescribed by a doctor. It is excreted in breast milk, so caution should be taken when administered to nursing mothers.
Kidney function: Patients with impaired renal function should be closely monitored when receiving high doses of cloxacillin.
Drug Interactions:Cloxacillin may interact with certain other medications, including:
Probenecid: This may increase the levels of cloxacillin in the blood by inhibiting its renal excretion.
Anticoagulants: Cloxacillin may increase the effects of anticoagulant drugs like warfarin.
Other antibiotics: Combination therapy with other antibiotics, especially those affecting cell wall synthesis, may result in synergistic effects but should be monitored carefully.
Storage:Oral forms: Should be stored at room temperature, away from heat and moisture.

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We are offering high quality of Dabigatran We are known for manufacturing, exporting, distributing, trading and supplying Dabigatranin Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Dabigatranin Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.
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Shreeji Pharma International currently export Dabigatran to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries
Dabigatran is an oral anticoagulant (blood thinner) that is used to prevent and treat thromboembolic disorders like deep vein thrombosis (DVT), pulmonary embolism (PE), and to reduce the risk of stroke in patients with non-valvular atrial fibrillation. In its API (Active Pharmaceutical Ingredient) powder form, Dabigatran is typically used in the manufacturing of pharmaceutical products such as capsules and tablets.
Here are the detailed characteristics of Dabigatran API Powder:
1. Chemical Description:
Chemical Name: Dabigatran etexilate mesylate
Molecular Formula: C34H41N7O5·CH4O3S
Molecular Weight: 628.79 g/mol
Dabigatran is a prodrug that is converted in the body to its active form, dabigatran, after it is absorbed and metabolized. Dabigatran directly inhibits thrombin (Factor IIa), which is a key enzyme involved in the blood clotting process.
3. Uses:
Stroke Prevention in Atrial Fibrillation: Dabigatran is used in patients with non-valvular atrial fibrillation to reduce the risk of stroke and systemic embolism.
 replacement.
4. Physical Characteristics:
Appearance: Dabigatran API powder is typically a white to off-white crystalline powder.
Solubility: It is moderately soluble in water and ethanol, which is important for formulation into oral dosage forms.
Stability: Dabigatran is stable under normal storage conditions, but its active form (dabigatran) is sensitive to moisture.
5. Dosage Forms:
Dabigatran is commonly formulated in capsules, tablets, and occasionally in oral suspension forms for easier administration in certain patient populations (like pediatric or elderly patients).
It is available in various strengths, commonly in 75 mg, 110 mg, and 150 mg oral doses, depending on the specific condition being treated.
7. Side Effects:
Common side effects include:
Bleeding: As an anticoagulant, the most common side effect is bleeding, including serious bleeding complications.
Gastrointestinal symptoms: Nausea, dyspepsia, and abdominal pain are common.

Serious side effects (though rare) include:
Severe bleeding: This can include gastrointestinal bleeding or intracranial hemorrhage.
Hypersensitivity reactions: Rash, itching, or anaphylaxis (rare).
8. Precautions:

Drug Interactions: Dabigatran should not be taken with drugs that inhibit or induce P-glycoprotein, as this can affect dabigatran’s bioavailability.
9. Storage:
Dabigatran API powder should be stored in a cool, dry place away from light and moisture. The temperature should typically be between 15°C to 30°C (59°F to 86°F).
It should be kept in tightly sealed containers to prevent exposure to moisture.

Additional Information:

• Production Capacity: 1 mt
• Delivery Time: Prompt
• Packaging Details: drum

Product Details:

We are offering high quality of Cilnidipine . We are known for manufacturing, exporting, distributing, trading and supplying Cilnidipine in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity andeffectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplierof Cilnidipine in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplierof Cilnidipine. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Cilnidipine  as well as Intermediates of Cilnidipine .Shreeji Pharma International is exporter, supplier, distributor and manufacturers of theActive Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Cilnidipine to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, CentralAmerican Countries and in European countries. 
Cilnidipine is a medication primarily used to treat hypertension (high blood pressure). It belongs to the class of drugs known as calcium channel blockers. The powder form of cilnidipine is used for the preparation of oral doses, typically in hospitals or pharmacies that compound medications.Here is a more detailed description of cilnidipine powder:

Chemical Information:
Chemical Name: 1-(3-Phenylpropyl)-4-(3-nitrophenyl)-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate
Molecular Formula: C22H26N2O4
Molecular Weight: 394.46 g/mol
Pharmacology:
Cilnidipine works by blocking calcium channels, which reduces the influx of calcium into the smooth muscle cells of blood vessels and the heart. This results in:
Vasodilation (widening of blood vessels), reducing blood pressure.
It has a dual mechanism of action, blocking both L-type calcium channels (affecting vascular smooth muscle) and N-type calcium channels (affecting the heart).
Benefits:
Antihypertensive Action: Cilnidipine is used to lower blood pressure in patients with hypertension, reducing the risk of complications like stroke, heart attack, or kidney damage.
Improved Tolerability: Compared to other calcium channel blockers, cilnidipine has a favorable profile in terms of side effects, particularly in avoiding reflex tachycardia (an increase in heart rate).
Reduced Risk of Fluid Retention: Unlike some other antihypertensives, cilnidipine may have a lower incidence of edema (fluid retention).
Administration:
Cilnidipine in powder form is typically compounded into tablets or oral solutions. The exact dosage will depend on the patient's needs and should be prescribed by a healthcare provider.
It is often administered in starting doses of 5-10 mg once daily, but the dose can be adjusted based on the patient's response.
Side Effects:
Common side effects of cilnidipine include:
Headache
Dizziness
Flushing
Edema (swelling)
Fatigue
Severe side effects, though rare, may include:
Severe hypotension (low blood pressure)
Heart block or arrhythmias (irregular heartbeat)
Liver enzyme abnormalities
Storage:
Cilnidipine powder should be stored in a cool, dry place, away from direct light, and according to the manufacturer's instructions, typically at room temperature (15°C–30°C or 59°F–86°F).
Contraindications:
Cilnidipine should not be used in patients with severe hypotension, heart failure with low output, or those with known hypersensitivity to the drug.
Caution should be exercised in patients with hepatic or renal impairment.

Additional Information:

• Delivery Time: immediate
• Packaging Details: drum packing with HDPE DRUM

Product Details:

We are offering high quality of Acyclovir Sodium Sterile. We are known for manufacturing, exporting, distributing, trading and supplying Acyclovir Sodium Sterile in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Acyclovir Sodium Sterile in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Acyclovir Sodium Sterile. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Acyclovir Sodium Sterile as well as Intermediates of Acyclovir Sodium Sterile.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Acyclovir Sodium Sterile to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

1. General Information

Chemical Name: Acyclovir Sodium

Synonyms: Sodium Acyclovir, Acyclovir Sodium Salt

Molecular Formula: C8H10N5NaO3

Molecular Weight: 247.19 g/mol

CAS Number: 69610-40-8

Appearance: White to off-white crystalline powder

Solubility: Highly soluble in water, slightly soluble in alcohol

2. Description & Properties

Acyclovir Sodium is the sodium salt form of acyclovir, a synthetic nucleoside analog with antiviral activity. It is primarily used to treat infections caused by herpes simplex virus (HSV) and varicella-zoster virus (VZV). The sodium form allows for better solubility and intravenous administration.

3. Mechanism of Action

Acyclovir is a guanine analog that gets phosphorylated by viral thymidine kinase into acyclovir monophosphate. This is further converted into acyclovir triphosphate, which inhibits viral DNA polymerase, preventing viral DNA replication.

4. Uses & Applications

Treatment of Herpes Simplex Virus (HSV-1 and HSV-2) infections

Management of Varicella-Zoster Virus (VZV) infections, including chickenpox and shingles

Prevention of cytomegalovirus (CMV) reactivation in immunocompromised patients

Used in IV form for severe herpes infections, including encephalitis and neonatal herpes

5. Dosage & Administration

Intravenous (IV) Form: Administered in hospitals for severe infections

Oral Dosage Forms: Converted into oral acyclovir for mild infections (after formulation)

Topical Use: Sometimes compounded for direct application on lesions

6. Storage & Stability

Store in a cool, dry place at controlled room temperature (15°C – 30°C)

Protect from moisture and direct sunlight

Ensure proper sealing to prevent degradation

7. Precautions & Warnings

Renal Impairment: Dosage adjustment required in patients with kidney dysfunction

Hydration: Adequate hydration is necessary to prevent nephrotoxicity

Pregnancy & Lactation: Generally considered safe but should be used under medical supervision

Side Effects: Possible nausea, headache, dizziness, and in IV use, renal toxicity and neurotoxicity in high doses

8. Quality Control & Purity

Purity: Typically ≥ 99% (HPLC analysis)

Impurity Limits: Complies with pharmacopeial standards (USP, BP, EP)

Microbial Limits: Must meet sterility requirements for IV formulations

Additional Information:

• Delivery Time: immediate
• Packaging Details: 25 kg drum pack