Active Pharmaceuticals Ingredient 7

Product Details:

We are offering high quality of KETOCONAZOLE We are known for manufacturing, exporting, distributing, trading and supplying KETOCONAZOLE in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of KETOCONAZOLE in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of KETOCONAZOLE NowadaysShreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing KETOCONAZOLE as well as Intermediates of KETOCONAZOLE .Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export KETOCONAZOLE to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries
- Technical Specifications  :
Name:Ketoconazole
CAS No.:65277-42-1 
Formula:C₂₆H₂₈Cl₂H₄O₄
Molecular Weight:531.44 .
Synonyms:Ketoconazole [USAN:BAN:INN:JAN];Ketoconazol [INN-Spanish];1-acetyl-4-(4-{[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine;Ketoconazole (JAN/USP);Nizoral (TN);
EINECS:265-667-4
Density:1.38 cm³
Melting Point:146 °C
Boiling Point:753.4 °C at 760 mmHg
Flash Point:409.4 °C
Appearance:White powder
Transport Information:UN 2811 6.1/PG 3
- Introduction of product:  Ketoconazole topical (for the skin) is an antifungal medicine used to treat infections such as athlete's foot, jock itch, ringworm, and seborrhea (dry, flaking skin or dandruff).
- How does it work?: It works by killing the yeasts (fungi) that cause the infections. The most common side effects of the cream and shampoo are irritated or red skin.
- Applications. Or where it is used:The medications are used for treating skin infections such as athlete's foot, jock itch and ringworm. Ketoconazole is also used to treat skin conditions like tinea Versicolor, a fungal infection which causes lightening or darkening of skin, neck, chest, arms and legs.
- How to use: Use a small amount of water to wet your skin in the area where you will apply ketoconazole shampoo. Apply the shampoo to the affected skin and a large area around it. Use your fingers to rub the shampoo until it forms a lather.Leave the shampoo on your skin for 5 minutes.
- Dosage of usage:Fungal InfectionsIndicated for the treatment of thefollowing systemic fungal infections in patients who have failed or who are intolerant to other therapies:  chromomycosis, and paracoccidioidomycosis
- Side effects:Common side effects of Ketoconazole include:Nausea and vomiting,Itching or skin rash,Abdominal or stomach pain,Less common side effects of ketoconazole include:,Hair loss,Headache,Dizziness,High levels of fat in the blood hyperlideme ,Drowsiness,Fever,Chills,Bulging fontanelles,Depression,Swollen breast tissue in males,Diarrea,Impotence,Low blood platelet count (thrombocytopenia).

 Chemical Information:

Chemical Name: Ketoconazole

CAS Number: 65277-42-1

Molecular Formula: C₂₆H₂₈Cl₂N₄O₄

Molecular Weight: 531.43 g/mol

 

Additional Information:

• Item Code: 65277-42-1
• Port of Dispatch: INDIA
• Production Capacity: 20 MT
• Delivery Time: PROMPT
• Packaging Details: DRUM

Product Details:

We are offering high quality of Flucloxacillin Sodium Powder. We are known for manufacturing, exporting, distributing, trading and supplying Flucloxacillin Sodium Powder in maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Flucloxacillin Sodium Powder in Gujarat India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Flucloxacillin Sodium Powder.  Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Flucloxacillin Sodium Powder  as well as Intermediates of Flucloxacillin Sodium Powder.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Flucloxacillin Sodium Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Chemical Information:

IUPAC Name: (2S,5R,6R)-6-(Aminoacetamido)-3,3-dimethyl-7-oxo-1,2,3,4-tetrahydropyrrolo[3,4-b]quinolin-5-yl 2-(4-methylphenyl)-1-oxopropan-2-yl phosphate sodium salt

Molecular Formula: C17H16N2NaO5S

Molecular Weight: 406.38 g/mol

CAS Number: 34442-29-4

Flucloxacillin Sodium is a type of antibiotic that belongs to the class of drugs known as penicillins. It is primarily used to treat infections caused by gram-positive bacteria, especially Staphylococcus aureus. Here is a detailed description of flucloxacillin sodium:

Mechanism of Action

Flucloxacillin sodium works by inhibiting the bacterial cell wall synthesis. It binds to specific proteins (penicillin-binding proteins) on the bacteria's cell wall, preventing the bacteria from forming a stable cell wall. This leads to bacterial cell lysis (rupture) and death. It is beta-lactamase resistant, meaning it is not easily broken down by beta-lactamase enzymes that some bacteria produce to resist other penicillins.

Indications

Flucloxacillin sodium is mainly used for infections caused by susceptible organisms, particularly Staphylococcus species, such as:

Skin and soft tissue infections, including boils, abscesses, and cellulitis.

Respiratory infections, such as pneumonia.

Bone and joint infections, like osteomyelitis.

Endocarditis (infection of the heart's lining).

Urinary tract infections (UTIs) caused by sensitive bacteria.

It is also used in treating infections in patients with prosthetic devices or those who have undergone surgical procedures.

Side Effects

While flucloxacillin sodium is generally well-tolerated, it can cause side effects, including:

Gastrointestinal issues, such as nausea, vomiting, and diarrhea.

Rashes or skin reactions.

Hepatotoxicity (liver toxicity), which may present as jaundice.

Hypersensitivity reactions, including anaphylaxis in rare cases.

Renal issues, such as nephritis, are possible with prolonged use.

Blood disorders, like neutropenia (low white blood cells) or thrombocytopenia (low platelet count).

 

 

 

 

 

Additional Information:

• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: INDIA
• Delivery Time: Immediate
• Packaging Details: 25kg HDPE Drum Packing.

Product Details:

We are offering high quality of Timolol Maleate. We are known for manufacturing, exporting, distributing, trading and supplying Timolol Maleate  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Timolol Maleate  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Timolol Maleate. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Timolol Maleate as well as Intermediates of Timolol Maleate.  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Timolol Maleate to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
 
Timolol Maleate is a non-selective beta-blocker commonly used in the treatment of various cardiovascular conditions and glaucoma. It works by reducing the heart rate, decreasing blood pressure, and lowering intraocular pressure in the eye. Timolol Maleate is particularly important in the management of hypertension, heart-related conditions, and in treating ocular hypertension and glaucoma.
Description & Properties:
Chemical Formula: C13H24N4O3·C4H4O4
Molecular Weight: 432.46 g/mol
Appearance: White to off-white crystalline powder.
Solubility: Soluble in water and alcohol.
Melting Point: Timolol Maleate typically melts around 150°C.
Timolol Maleate is the maleate salt form of Timolol, which improves the compound's solubility and stability, particularly for use in medications. It is available in both oral and topical forms, the latter primarily used in eye drops for ocular conditions.
Uses:
Timolol Maleate is used for several medical conditions, including:
Hypertension (High Blood Pressure): It is used to reduce high blood pressure by decreasing the heart's workload.
Side Effects:
While Timolol Maleate is generally well-tolerated, it can cause side effects, especially at higher doses:
Cardiovascular: Bradycardia (slow heart rate), hypotension (low blood pressure), heart failure.
Respiratory: Bronchospasm (especially in asthmatic patients), wheezing, or shortness of breath due to beta-2 receptor blockade.
Ophthalmic (when used as eye drops): Burning, stinging, dry eyes, or blurred vision.
Central Nervous System: Dizziness, fatigue, depression, or headache.
Gastrointestinal: Nausea, diarrhea, or stomach discomfort.
Skin Reactions: Rash, itching, or changes in skin color.
Precautions:
Asthma and Chronic Obstructive Pulmonary Disease (COPD): Since Timolol is a non-selective beta-blocker, it can exacerbate bronchospasm in patients with asthma or COPD. It should generally be avoided in these individuals.
Bradycardia or Heart Block: Patients with low heart rate or heart block (unless they have a pacemaker) should not take Timolol.
Storage:
Store in a cool, dry place away from light.

 

 

Additional Information:

• Item Code: 26921-17-5
• Delivery Time: prompt
• Packaging Details: 25 KG Drum

Product Details:

We are offering high quality of Amiloride. We are known for manufacturing, exporting, distributing, trading and supplying Amiloride in Gujarat India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier

Amiloride in Gujarat India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Amiloride. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Amiloride as well as Intermediates of Amiloride.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Amiloride to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Chemical Name: Amiloride hydrochloride (commonly used form)
Molecular Formula: C₆H₈ClN₇O
Molecular Weight: 229.63 g/mol (as the base), 266.1 g/mol (as hydrochloride)
CAS Number: 2609-46-3 (Amiloride); 2016-88-8 (Amiloride Hydrochloride)
Appearance: Yellow crystalline powder
Solubility: Slightly soluble in water and methanol, practically insoluble in organic solvents
Melting Point: ~290°C (decomposes)
Purity: Typically ≥98% (depending on the supplier and grade)
Storage Conditions: Store in a cool, dry place, protected from light and moisture

Description & Uses : Amiloride is a potassium-sparing diuretic that works by inhibiting sodium reabsorption in the kidneys, thereby reducing potassium loss. It is often used in combination with other diuretics, such as hydrochlorothiazide, to treat conditions like hypertension, heart failure, and edema.

Mechanism of Action : Amiloride selectively blocks epithelial sodium channels (ENaC) in the distal tubules and collecting ducts of the nephron, preventing sodium reabsorption and leading to increased sodium excretion while retaining potassium.

Applications

Medical Uses:Treatment of hypertension (high blood pressure)
Management of congestive heart failure
Edema treatment in conditions like cirrhosis and nephrotic syndrome
Used in combination with other diuretics to counteract potassium loss

Research Uses:Studied for its effects on ion transport and epithelial sodium channels
Investigated in cystic fibrosis and cancer research

Storage & Stability : Storage Conditions: Keep in a cool, dry place at controlled room temperature (15–25°C). Protect from light and moisture.

Shelf Life: Typically stable for at least 2 years if stored properly.

Amiloride is a potassium-sparing diuretic used to treat high blood pressure and fluid retention. Like all medications, it can cause side effects. Here are some potential side effects:

Common Side Effects

Nausea,Vomiting,Headache,Dizziness,Weakness,Stomach pain,Fatigue

Serious Side Effects (Seek Medical Help)

High potassium levels (hyperkalemia):

Irregular heartbeat,Muscle weakness,Numbness or tingling

Low sodium levels (hyponatremia):

Confusion,Seizures,Severe fatigue

Allergic reactions:

Rash,Swelling (face, tongue, throat),Trouble breathing

Kidney problems:

Decreased urination,Swelling in legs or feet,Difficulty breathing

Additional Information:

• Port of Dispatch: India
• Production Capacity: 20Mt
• Delivery Time: Prompt
• Packaging Details: HDPE DRUM PACK

Product Details:

We are offering high quality of Methyl Sulfonyl Methane.We are known for manufacturing, exporting, distributing, trading and supplying Methyl Sulfonyl Methane in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Methyl Sulfonyl  Methane in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of  Methyl Salicylate. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Methyl Sulfonyl Methane as well as Intermediates of  Methyl Sulfonyl Methane. Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Methyl Sulfonyl Methane countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Methylsulfonylmethane (MSM) - Detailed Description

Overview

Methylsulfonylmethane (MSM) is an organic sulfur-containing compound that is naturally found in plants, animals, and humans. It is commonly used as a dietary supplement due to its potential health benefits, particularly in supporting joint health, reducing inflammation, and improving skin and hair conditions.

Chemical & Physical Properties

Chemical Formula: C2H6O2SC_2H_6O_2SC2​H6​O2​S

Molecular Weight: 94.13 g/mol

Synonyms: Dimethyl sulfone (DMSO₂), Methyl sulfone

Appearance: White crystalline powder

Solubility: Soluble in water and organic solvents

Melting Point: ~108-110°C

Sources of MSM

MSM is naturally found in:

Fresh fruits and vegetables (e.g., tomatoes, alfalfa, onions, garlic)

Grains and legumes

Meat, fish, and dairy products

Some plants, such as horsetail and aloe vera

However, the MSM found in dietary supplements is usually synthesized from DMSO (dimethyl sulfoxide) through an oxidation process.

Health Benefits of MSM

Joint & Bone Health:

Supports cartilage formation and repair.

Reduces symptoms of osteoarthritis and joint pain by lowering inflammation.

Works synergistically with glucosamine and chondroitin for improved mobility.

Anti-Inflammatory Properties:

Helps reduce inflammation by inhibiting cytokines and oxidative stress.

May benefit individuals with arthritis, tendonitis, and muscle soreness.

Skin, Hair, and Nail Health:

Promotes collagen and keratin production, improving skin elasticity and strength.

May reduce wrinkles, dryness, and improve wound healing.

Strengthens nails and promotes hair growth.

Exercise Recovery & Muscle Performance:

Reduces muscle damage and soreness after intense exercise.

Enhances recovery time by decreasing oxidative stress and inflammation.

Immune System Support:

Acts as an antioxidant, reducing oxidative damage.

Supports glutathione production, an essential antioxidant for immune function.

Detoxification & Liver Support:

Assists in the removal of heavy metals and toxins.

Supports liver health and metabolic functions.May cause headaches or fatigue in rare cases.

 

 

 

 

 

 

Additional Information:

• Item Code: 67-71-0
• Delivery Time: Prompt
• Packaging Details: Drum

Product Details:

We are offering high quality of Bromhexine. We are known for manufacturing, exporting, distributing, trading and supplying Bromhexine in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectivenes
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Bromhexine in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Bromhexine. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Bromhexine as well as Intermediates of Bromhexine.  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

 Shreeji Pharma International currently export Bromhexine to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Bromhexine is a mucolytic and expectorant drug used to treat respiratory conditions characterized by thick, sticky mucus. It works by breaking down the structure of mucus, making it easier to clear out from the respiratory tract. Below is a detailed specification for Bromhexine:
Chemical Name:
Bromhexine Hydrochloride
Mechanism of Action:
Bromhexine works by depolymerizing mucopolysaccharide fibers in the mucus, making it less viscous and easier to expectorate.
It stimulates the production of surfactant, a substance that helps maintain the fluidity of mucus in the lungs.
It also increases the clearance of mucus by promoting the ciliary action in the respiratory tract, making it easier to expel mucus.
Indications:
Chronic Obstructive Pulmonary Disease (COPD)
Acute and chronic bronchitis
Asthma (particularly with mucus hypersecretion)
Cystic fibrosis
Sinusitis (with mucus accumulation)
Post-surgical airway management (to help clear mucus)
Forms and Dosage:
Bromhexine is available in various formulations, including tablets, syrups, and intravenous injections.Tablets:
Dosage: Typically 8 mg to 16 mg, taken 2-3 times daily depending on the severity of the condition.
Syrup:
Dosage: Typically 4-8 mg per dose, 2-3 times a day, based on the patient’s age and health status.
Injectable:
Dosage: For hospitalized patients, bromhexine may be administered intravenously under medical supervision.
Pharmacokinetics:
Absorption: Bromhexine is well absorbed from the gastrointestinal tract.
Distribution: It is widely distributed throughout the body, particularly in the lungs and respiratory tract.
Metabolism: It is metabolized in the liver to active metabolites, including Ambroxol, which also has mucolytic and expectorant properties.
Elimination: Bromhexine is excreted primarily in the urine as its metabolites.
Side Effects:
Though bromhexine is generally safe, some side effects can occur, including:
Gastrointestinal issues: Nausea, vomiting, abdominal discomfort, or diarrhea.
Skin reactions: Rash, itching, or hives.
Respiratory issues: Rarely, it may cause bronchospasm or worsen asthma symptoms.
Allergic reactions: Including anaphylaxis, though this is extremely rare.
Contraindications:
Bromhexine should be avoided in patients with known hypersensitivity to bromhexine or any of its components.

Additional Information:

• Item Code: 611-75-6
• Delivery Time: Prompt
• Packaging Details: 25 kgs Drum Packing

Product Details:

We are offering high quality of Ambroxol. We are known for manufacturing, exporting, distributing, trading and supplying Ambroxol in Gujarat India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier

Ambroxol in Gujarat India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Ambroxol. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Ambroxol as well as Intermediates of Ambroxol.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Ambroxol to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Chemical Name: Ambroxol Hydrochloride

Molecular Formula: C13H18Br2N2O

Molecular Weight: 378.1 g/mol

CAS Number: 18683-91-5

Appearance: White or slightly yellow crystalline powder

Solubility: Soluble in water, methanol, and ethanol; slightly soluble in chloroform; practically insoluble in ether.

Description & Uses:Ambroxol is a mucolytic agent used to improve mucus clearance in respiratory conditions. It acts by breaking down mucopolysaccharides, reducing mucus viscosity, and promoting its expulsion. It also has mild anti-inflammatory and local anesthetic effects.

Technical Specifications:

Purity: ≥ 99%

Melting Point: 235–240°C

pH (5% Solution): 5.0–6.5

Loss on Drying: ≤ 0.5%

Residue on Ignition: ≤ 0.1%

Heavy Metals: ≤ 10 ppm

Assay (HPLC): 99.0–101.0%

Applications:Used in pharmaceutical formulations for cough and cold remedies

Active ingredient in syrups, tablets, and inhalation solutions Enhances pulmonary surfactant production Supports lung function in respiratory conditions such as COPD, asthma, and bronchitis

Ambroxol is a mucolytic agent used primarily to treat respiratory conditions associated with excessive mucus production. It works by breaking down and thinning mucus in the airways, making it easier to cough up. It is commonly used in conditions such as bronchitis, chronic obstructive pulmonary disease (COPD), and asthma.

Uses:Treatment of productive cough

Relief from thick mucus in the respiratory tract

Supportive therapy for bronchial asthma, pneumonia, and other lung diseases

Dosage Forms: Tablets,Syrup,Lozenges,Inhalation solution,Injection

Precautions:

Allergic Reactions: Avoid if you have a known allergy to Ambroxol or similar drugs.

Pregnancy & Breastfeeding: Use only if prescribed by a doctor, as safety during pregnancy and lactation is not fully established.

Gastrointestinal Disorders: Use with caution in patients with a history of stomach ulcers or gastritis, as it may increase gastric acid production.

Children: Use in children should follow the prescribed dosage to avoid overdose risks.

Common side effects include:Nausea,Vomiting,Diarrhea,Stomach pain,Dry mouth or throat irritation, Rare but serious side effects:Allergic reactions (rash, itching, swelling),Severe skin reactions like Stevens-Johnson Syndrome (rare), Difficulty breathing (in very rare cases)

Additional Information:

• Delivery Time: immediate
• Packaging Details: HDPE DRUM PACK

Product Details:

We are offering high quality of Phenytoin Api. We are known for manufacturing, exporting, distributing, trading and supplying Phenytoin Api in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Phenytoin Api in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Phenytoin Api. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Phenytoin Api as well as Intermediates of Phenytoin Api.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Phenytoin Api to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

1. General Overview: Phenytoin is an active pharmaceutical ingredient (API) primarily used as an anticonvulsant to control and prevent seizures. It stabilizes neuronal membranes and reduces seizure activity by limiting the repetitive firing of action potentials.

2. Chemical Information: 5,5-Diphenylimidazolidine-2,4-dione, Molecular Formula: C₁₅H₁₂N₂O₂, Molecular Weight: 252.27 g/mol, CAS Number: 57-41-0, IUPAC Name: 5,5-Diphenyl-2,4-imidazolidinedione, Synonyms: Diphenylhydantoin, Sodium diphenylhydantoin

3. Physical & Chemical Properties: Appearance: White or off-white crystalline powder, Odor: Odorless, Solubility: Slightly soluble in water, Freely soluble in acetone and ethanol, Soluble in alkaline solutions, Melting Point: 295–298°C (decomposes), pH: Neutral to slightly acidic in aqueous solutions, Stability: Stable under normal conditions, sensitive to moisture

4. Mechanism of Action:Phenytoin primarily works by blocking voltage-gated sodium channels in the brain, reducing abnormal electrical activity and stabilizing neuronal excitability. 5. Uses and Applications: Anticonvulsant: Used for treating epilepsy, including tonic-clonic (grand mal) and partial seizures, Antiarrhythmic: Occasionally used for managing certain types of cardiac arrhythmias, Neurosurgical Use: Used in head trauma cases to prevent seizure onset.

6. Pharmacokinetics: Absorption: Slowly but completely absorbed in the gastrointestinal tract, Bioavailability: ~85-95%, Protein Binding: ~90% (mainly to albumin), Metabolism: Primarily hepatic via CYP2C9 and CYP2C19, Half-life: 10–22 hours (varies by patient), Excretion: Mainly in urine as hydroxylated metabolites

7. Storage and Handling: Store in a cool, dry place away from moisture and direct light., Keep tightly closed in an airtight container., Avoid exposure to excessive heat and humidity.

8. Regulatory & Safety Information: FDA/WHO Status: Approved for medical use

GHS Classification: May cause eye irritation, Potential reproductive toxicity, Long-term exposure may lead to bone marrow suppression

Precautions: Avoid inhalation and contact with skin, Use personal protective equipment (PPE) when handling

9. Common Formulations Using Phenytoin API: Phenytoin Sodium Injection, Phenytoin Oral Suspension, Phenytoin Tablets & Capsules

Additional Information:

• Item Code: 0641-0493-21
• Delivery Time: PROMPT
• Packaging Details: DRUM

Product Details:

We are offering high quality of Nicotine Polacrilex Powder. We are known for manufacturing, exporting, distributing, trading and supplying Nicotine Polacrilex Powder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Nicotine Polacrilex Powder in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Nicotine Polacrilex Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Nicotine Polacrilex Powder as well as Intermediates of Nicotine Polacrilex Powder.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Nicotine Polacrilex Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Nicotine Polacrilex is a nicotine resin complex in which nicotine is bound to an ion-exchange resin (usually polacrilin). It is commonly used in nicotine replacement therapies (NRT) such as gums, lozenges, and other delivery systems to help reduce withdrawal symptoms in people trying to quit smoking or reduce nicotine dependence.

Chemical & Physical Properties

Chemical Formula: C₁₀H₁₄N₂ (for nicotine)

Molecular Weight: 162.23 g/mol

Appearance: Fine, off-white to light tan powder

Odor: Slight nicotine odor

Solubility: Partially soluble in water; soluble in acidic solutions

pH (in solution): 5.5 – 7.5

Stability: Stable under normal storage conditions; avoid moisture and extreme heat

How Nicotine Polacrilex Works

Nicotine Polacrilex is designed to deliver nicotine in a controlled manner. When used in gums or lozenges, the nicotine is gradually released and absorbed through the oral mucosa, mimicking the nicotine absorption profile of smoking but at a lower and controlled dose.

Common Uses

Nicotine Replacement Therapy (NRT)

Found in nicotine gums, lozenges, and sublingual tablets

Helps reduce cravings and withdrawal symptoms

Pharmaceutical & Research Applications

Used in formulation development for controlled-release nicotine delivery

Studied in behavioral and addiction research

Custom Formulations

Can be used in nicotine pouches, dissolvable films, and sprays

Benefits of Nicotine Polacrilex

Controlled Release: Provides a steady, slow release of nicotine

Improved Absorption: Enhances nicotine bioavailability via oral mucosa

Reduced Side Effects: Compared to smoking, it reduces exposure to harmful combustion byproducts

FDA Approved for NRT: Commonly used in over-the-counter nicotine replacement products

Storage & Handling

Storage Conditions: Keep in a cool, dry place away from moisture and light

Shelf Life: Typically 2-3 years when stored properly

Precautions: Handle with care, as nicotine is a toxic and addictive substance

Additional Information:

• Item Code: 96055-45-7
• Delivery Time: PROMPT
• Packaging Details: DRUM

Product Details:

We are offering high quality of Moxifloxacin HCL. We are known for manufacturing, exporting, distributing, trading and supplying Moxifloxacin HCL in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Moxifloxacin HCL in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Moxifloxacin HCL. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Moxifloxacin HCL as well as Intermediates of Moxifloxacin HCL.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Moxifloxacin HCL to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

1. General Information

Moxifloxacin Hydrochloride (HCl) is a broad-spectrum fluoroquinolone antibiotic used to treat bacterial infections. It is available in oral, intravenous (IV), and ophthalmic (eye drops) formulations.

2. Chemical Properties

IUPAC Name: 1-Cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid hydrochloride

Molecular Formula: C₂₁H₂₄FN₃O₄ HCl

Molecular Weight: 437.9 g/mol (hydrochloride salt)

Chemical Class: Fluoroquinolone

3. Mechanism of Action (MOA)

Moxifloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, which are essential for bacterial DNA replication, transcription, and repair. This leads to bacterial cell death, making it a bactericidal antibiotic.

4. Pharmacokinetics

Absorption: Well absorbed orally (bioavailability ~90%)

Distribution: Widely distributed in tissues, including the lungs, skin, and sinuses

Protein Binding: ~50%

Metabolism: Primarily hepatic (liver) metabolism via glucuronidation and sulfation

Elimination Half-Life: ~12 hours

Excretion: Primarily fecal (45%), renal (20%)

5. Indications (Uses)

Moxifloxacin is used to treat infections caused by susceptible bacteria, including:

Respiratory Tract Infections , Community-acquired pneumonia (CAP), Acute exacerbation of , chronic bronchitis, Acute bacterial sinusitis, Skin and Soft Tissue Infections, Intra-Abdominal  Infections, Bacterial Conjunctivitis (Ophthalmic Form)

6. Dosage & Administration

Oral/IV: 400 mg once daily

Ophthalmic (Eye Drops): 1 drop in affected eye(s) 3 times daily for 7 days

7. Contraindications

Hypersensitivity to moxifloxacin or other fluoroquinolones

History of QT prolongation or cardiac arrhythmias

Myasthenia gravis (may worsen muscle weakness)

8. Side Effects

Common: Nausea, diarrhea, dizziness, headache

Serious: QT prolongation (risk of arrhythmias), Tendon rupture (especially in older adults or those on corticosteroids), Peripheral neuropathy, Hepatotoxicity, Clostridioides difficile-associated diarrhea

9. Drug Interactions:Increased QT prolongation risk: Antiarrhythmics, antipsychotics, tricyclic antidepressants

Reduced absorption: Aluminum/magnesium antacids, iron supplements

Corticosteroids: Increased risk of tendon rupture

10. Storage Conditions

Tablets: Store at room temperature (15-30°C)

IV Solution: Protect from light; use within 24 hours after dilution

Eye Drops: Store at 2-25°C and do not freeze

Additional Information:

• Item Code: 293349
• Port of Dispatch: India
• Production Capacity: 20Mt
• Delivery Time: Prompt
• Packaging Details: Drum

Product Details:

 

We are offering high quality of Bronopol. We are known for manufacturing, exporting, distributing, trading and supplying Bronopol in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Bronopol in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Bronopol. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Bronopol as well as Intermediates of Bronopol.  Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Bronopol to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Bronopol (also known by its chemical name 2-Bromo-2-nitropropane-1,3-diol) is a broad-spectrum antimicrobial agent commonly used in a variety of applications, including cosmetics, personal care products, industrial water treatment, and as a preservative in pharmaceuticals. It is typically found as a white to off-white powder, and its chemical formula is C3H6BrNO3.
Detailed Description:
Chemical Structure and Properties:
IUPAC Name: 2-Bromo-2-nitropropane-1,3-diol.
Molecular Formula: C3H6BrNO3.
Molecular Weight: 199.99 g/mol.
Appearance: White to off-white crystalline powder.
Solubility: It is slightly soluble in water and ethanol, and more soluble in acetone.
Melting Point: Around 101°C (214°F).
Stability: Bronopol is stable under normal conditions but should be kept in tightly sealed containers away from direct sunlight and moisture to prevent decomposition.
Antimicrobial Action: Bronopol acts as a bactericide and fungicide, preventing the growth of microorganisms by disrupting their cell functions. It is effective against both gram-positive and gram-negative bacteria and some fungi, making it useful for preserving formulations and preventing microbial contamination in products.
Uses:
Cosmetics and Personal Care: Bronopol is commonly used as a preservative in a wide variety of products like shampoos, lotions, creams, deodorants, and other personal care items. It prevents the growth of bacteria, yeast, and molds, thereby extending the shelf life of these products.
Pharmaceuticals: It is used as a preservative in certain oral and topical medications, ensuring they remain free from microbial contamination.
Industrial Applications: Bronopol is employed in industrial applications, such as in the preservation of industrial fluids and in water treatment processes, to inhibit microbial growth and prevent biofilm formation.
Antiseptic: In some cases, it is used in antiseptic formulations, such as wound care products and disinfectants.
Safety and Handling:
Toxicity: Bronopol has low acute toxicity but can cause skin and eye irritation upon direct contact. Inhalation of its dust may cause respiratory irritation. Ingestion in large quantities could lead to nausea, vomiting, or more severe health effects.

 

Additional Information:

• Delivery Time: PROMPT
• Packaging Details: DRUM

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We are offering high quality of Nicotinic Acid. We are known for manufacturing, exporting, distributing, trading and supplying Nicotinic Acid in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Nicotinic Acid in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Nicotinic Acid. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Nicotinic Acid as well as Intermediates of Nicotinic Acid.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Nicotinic Acid to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

1. Overview:Nicotinic acid, commonly known as niacin (vitamin B3), is an essential water-soluble vitamin that plays a crucial role in cellular metabolism, energy production, and the maintenance of skin, nerves, and digestive health.

2. Chemical and Physical Properties:Chemical Formula: C₆H₅NO₂, Molecular Weight: 123.11 g/mol, Appearance: White, crystalline powder, Solubility: Soluble in water, ethanol, and slightly soluble in ether, Melting Point: 234-237°C

3. Sources of Nicotinic Acid: Animal sources: Liver, chicken, turkey, And fish, and eggs, Plant sources: Peanuts, mushrooms, whole grains, legumes, and seeds, Fortified foods: Breakfast cereals and flour-based products, Biosynthesis in the body

4. Biological Functions: Energy Metabolism: Niacin is a precursor to NAD and NADP, which are involved in ATP production through glycolysis, the Krebs cycle, and oxidative phosphorylation., DNA Repair and Cell Function: NAD-dependent enzymes regulate gene expression, DNA repair, and cell signaling., Lipid and Cholesterol Metabolism: Nicotinic acid can lower LDL (bad cholesterol) and triglycerides while increasing HDL (good cholesterol).

5. Medical Uses: Hyperlipidemia Treatment: Nicotinic acid (in pharmacological doses) is used to lower cholesterol and reduce cardiovascular disease risk., Pellagra Treatment: A deficiency of niacin leads to pellagra, characterized by the "4 Ds" - Dermatitis, Diarrhea, Dementia, and Death. Niacin supplementation effectively treats and prevents pellagra.

6. Recommended Daily Intake (RDI): Men: 16 mg/day, Women: 14 mg/day, Pregnant Women: 18 mg/day, Lactating Women: 17 mg/day

7. Deficiency and Symptoms: Niacin deficiency results in pellagra, which includes: Dermatitis: Photosensitive skin lesions, Diarrhea: Gastrointestinal distress, Dementia: Cognitive decline, depression, and memory loss.

8. Toxicity and Side Effects: Flushing: A common side effect characterized by redness, warmth, and tingling of the skin, Liver Damage: High doses may lead to hepatotoxicity, Gastrointestinal Issues: Nausea, vomiting, and stomach discomfort, Glucose Intolerance: High doses may impact blood sugar levels

9. Forms of Niacin Supplements: Immediate-Release (IR) Nicotinic Acid: Quickly absorbed but can cause flushing. Extended-Release (ER) Nicotinic Acid: Reduces flushing but has a higher risk of liver toxicity.

10. Conclusion: Nicotinic acid is an essential nutrient with important roles in energy production, metabolism, and cardiovascular health. While dietary intake is generally safe, pharmacological doses should be taken under medical supervision due to potential side effects.

Additional Information:

• Item Code: 8044-71-1
• Delivery Time: prompt
• Packaging Details: DRUM

Product Details:

We are offering high quality Zinc Pyrithione.We are known for manufacturing, exporting, distributing, trading and supplying Zinc Pyrithione in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Bisacodyl in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Bisacodyl Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing  Biperiden HCL as well as Intermediates of Bisacodyl.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Bisacodyl to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Zinc Pyrithione Powder is a chemical compound commonly used for its antimicrobial and antifungal properties. It is primarily used in formulations for the treatment of dandruff, seborrheic dermatitis, and various skin conditions. Zinc Pyrithione is also known for its ability to treat fungal infections of the scalp, skin, and other body areas.

Zinc Pyrithione Powder - Description and Details

Active Ingredient:

Name: Zinc Pyrithione

Chemical Structure:

Molecular Formula: C10H8N2O2S2Zn

Molecular Weight: 317.78 g/mol

Physical Characteristics:

Appearance: White to pale yellow powder, often crystalline in form.

Solubility: Slightly soluble in water, more soluble in organic solvents like ethanol.

Odor: Odorless or faintly characteristic, but usually non-obtrusive.

Pharmaceutical Formulation:

Form: Powder intended for use in topical formulations, shampoos, lotions, creams, or ointments.

Concentration: Typically, Zinc Pyrithione powder is used in concentrations ranging from 0.5% to 2% in final formulations, but this can vary.

Excipients: In topical formulations, Zinc Pyrithione powder is combined with excipients to improve its stability and efficacy, such as surfactants in shampoos or creams.

Fungicidal Action: It is particularly effective against Malassezia furfur, a yeast implicated in dandruff and seborrheic dermatitis.

Bactericidal Action: Zinc Pyrithione has also been shown to be effective against some bacteria, contributing to its use in acne and other skin conditions.

Indications:

Dandruff Treatment: Zinc Pyrithione is commonly used in dandruff shampoos and scalp treatments to reduce the fungal growth that contributes to flaking and itching.

Seborrheic Dermatitis: Used in creams and lotions to treat seborrheic dermatitis on the scalp, face, and body.

Psoriasis and Other Skin Conditions: It is used in topical treatments for psoriasis, eczema, and other skin disorders, where fungal infection or bacterial overgrowth is a concern.

Acne Treatment: Sometimes included in acne treatments due to its antibacterial properties.

Side Effects and Adverse Reactions:Common Side Effects:Skin irritation or redness (especially with prolonged use),Dryness or peeling of the skin or scalp,Itching or stinging at the site of application,Scaling or flaking of the skin (may occur as part of the treatment effect)

 

Additional Information:

• Production Capacity: 1 mt
• Delivery Time: prompt
• Packaging Details: DRUM

Product Details:

We are offering high quality of Doxycycline Hyclate. We are known for manufacturing, exporting, distributing, trading and supplying Doxycycline Hyclate in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Doxycycline Hyclate in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Doxycycline Hyclate. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Doxycycline Hyclate as well as Intermediates of  Doxycycline Hyclate.Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Doxycycline Hyclate to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Doxycycline Hyclate is an antibiotic used to treat a wide variety of bacterial infections. It is a tetracycline antibiotic and works by inhibiting the growth of bacteria, making it useful in treating infections caused by both gram-positive and gram-negative bacteria.
Description:
Chemical Name: 4-(Dimethylamino)-3,5-dimethyl-6-(6-oxopropyl)-1,4-dihydroxy-1,4,4a,5,10,10a-hexahydro-3,5-dimethyl-1,4,4a,5,10,10a-hexahydroxy-5,10a-dihydroxy-3,5-dimethyl-2-(dimethylamino)phenyl
Molecular Formula: C22H24N2O8 · HCl
CAS Number: 24390-14-5 (for doxycycline hyclate)
Appearance: Doxycycline Hyclate appears as a white to off-white crystalline powder, usually in its salt form with hydrochloride.
Uses:
Doxycycline Hyclate is prescribed for the treatment of a variety of infections, including: Respiratory Tract Infections: Pneumonia ' Bronchitis ,Sinusitis ,Pharyngitis ,Sexually Transmitted Infections (STIs): Chlamydia ,Gonorrhea,Skin and Soft Tissue Infections:Acne
Rosacea,Cellulitis,Tick-borne Diseases:Lyme disease
Rocky Mountain Spotted Fever ,Typhus ,Urinary Tract Infections (UTIs) Malaria Prevention and Treatment

Side Effects:
Most people tolerate doxycycline well, but some side effects can occur:
Gastrointestinal issues: nausea, vomiting, diarrhea, or upset stomach.
Photosensitivity: Increased sensitivity to sunlight, leading to a higher risk of sunburn.
Esophageal irritation: Can occur if the tablet or capsule is taken without enough water, leading to esophageal ulcers or irritation.
Allergic reactions: Rash, itching, or hives.
Teeth Discoloration: Doxycycline can cause permanent yellow-brown or gray staining of teeth if taken during tooth development (especially in children under 8 years old).
Liver toxicity: Rare, but high doses or prolonged use can lead to liver problems.
Storage:
Storage Conditions: Doxycycline Hyclate should be stored in a cool, dry place away from light and moisture. It should be kept at room temperature (20-25°C or 68-77°F) and kept out of reach of children.
Purity:
Purity: Pharmaceutical-grade Doxycycline Hyclate should have a purity of at least 98-99%. It must meet the quality standards set by organizations like the United States Pharmacopeia (USP) or the European Pharmacopoeia (EP).

Additional Information:

• Item Code: 24390-14-5
• Port of Dispatch: india
• Production Capacity: 1 MT.
• Delivery Time: prompt
• Packaging Details: drums

Product Details:

We are offering high quality of Tizanidine Hcl . We are known for manufacturing, exporting, distributing, trading and supplying Tizanidine Hcl   in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Tizanidine Hcl   in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Tizanidine Hcl . Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Tizanidine Hcl  as well as Intermediates of Tizanidine Hcl .  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Tizanidine Hcl  to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Tizanidine HCl is a muscle relaxant primarily used to manage muscle spasticity. It is a centrally acting alpha-2 adrenergic agonist that works by inhibiting the transmission of nerve impulses in the spinal cord, which helps to reduce muscle tone and spasms. Tizanidine is commonly prescribed for conditions involving spasticity due to neurological disorders, such as multiple sclerosis (MS), spinal cord injury, or cerebral palsy.
Description & Properties:
Chemical Formula: C9H8ClN3
Molecular Weight: 198.63 g/mol
Appearance: White to off-white crystalline powder.
Solubility: Soluble in water and alcohol.
Melting Point: Approximately 267–268°C.
Tizanidine is the hydrochloride salt form of the active compound, making it stable for use in oral medications. The medication is usually administered in tablet or capsule form and works by interacting with the alpha-2 adrenergic receptors in the central nervous system.
Uses:
Tizanidine is primarily used for:
Muscle Spasticity:
Multiple sclerosis: It helps manage spasticity (muscle stiffness and spasms) often associated with MS.
Spinal cord injury: It is used to reduce spasticity caused by spinal cord injuries.
Cerebral palsy: Helps manage spasticity in patients with cerebral palsy.
Short-Term Management of Acute Muscle Spasms: Tizanidine may be used to manage acute muscle spasms that can occur from injuries or other conditions that affect the musculoskeletal system.
Side Effects:
Common side effects of Tizanidine include:
Drowsiness or sedation, as it affects the central nervous system.
Dry mouth, which is often reported in patients taking Tizanidine.
Dizziness or lightheadedness, particularly when standing up quickly (orthostatic hypotension).
Weakness or fatigue, especially during the initial stages of treatment.
Hypotension (low blood pressure), which can cause dizziness or fainting in some individuals.
Liver function changes: In rare cases, Tizanidine can cause liver enzyme elevations, and long-term use should be monitored.
Nausea or vomiting may also occur, particularly at higher doses.
Precautions:
Liver Disease: Tizanidine should be used with caution or avoided in patients with liver impairment. Liver function should be monitored regularly, as the drug is metabolized in the liver.
Storage:
Storage conditions: Tizanidine should be stored at room temperature (20–25°C or 68–77°F), away from moisture and heat.
Shelf life: Keep the medication in its original packaging, tightly closed, and out of reach of children.

Additional Information:

• Delivery Time: PROMPT
• Packaging Details: DRUM

Product Details:

We are offering high quality of Olanzapine Api Powder. We are known for manufacturing, exporting, distributing, trading and supplying Olanzapine Api Powder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Olanzapine Api Powder in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Olanzapine Api Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Olanzapine Api Powder as well as Intermediates of Olanzapine Api Powder.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Olanzapine Api Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Olanzapine is a Yellow Crystalline Powder and an atypical antipsychotic. It is approved by the U.S. Food and Drug Administration (FDA) for the treatment of schizophrenia and bipolar disorder.

1. General Overview

Olanzapine is an atypical antipsychotic drug primarily used for the treatment of schizophrenia and bipolar disorder. It is available as an Active Pharmaceutical Ingredient (API) powder, which is used by pharmaceutical manufacturers to formulate various dosage forms like tablets and injections.

2. Chemical Information

IUPAC Name: 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine

CAS Number: 132539-06-1

Molecular Formula: C₁₇H₂₀N₄S

Molecular Weight: 312.43 g/mol

Structure: It contains a thienobenzodiazepine core with a piperazine ring.

3. Physical Properties

Appearance: White to pale yellow crystalline powder

Solubility: Slightly soluble in water, freely soluble in chloroform, and sparingly soluble in ethanol

Melting Point: 195-197°C

Odor: Odorless

4. Pharmacology

Mechanism of Action:
Olanzapine works by blocking dopamine (D₂) and serotonin (5-HT₂A) receptors in the brain, which helps to restore neurotransmitter balance and reduce psychotic symptoms. It also has activity on histamine, alpha-adrenergic, and muscarinic receptors.

Therapeutic Uses:

Treatment of schizophrenia

Management of bipolar disorder (acute manic or mixed episodes)

Adjunct treatment in major depressive disorder (in combination with fluoxetine)

5. Manufacturing & Quality Standards

Purity: Usually ≥99% (varies based on manufacturer and specifications)

Quality Standards: Complies with USP, BP, EP, and IP pharmacopoeial standards

Stability: Stable under normal storage conditions, but should be protected from moisture and light

6. Storage & Handling

Storage Conditions: Store in a cool, dry place at controlled room temperature (15-30°C).

Handling Precautions:

Use personal protective equipment (PPE) such as gloves, goggles, and a mask.

Avoid direct inhalation or ingestion.

Handle in a well-ventilated area.

7. Regulatory & Market Information

Regulatory Status: Approved by US FDA, EMA, TGA, and other global regulatory bodies

Market Availability: Supplied by various API manufacturers across India, China, Europe, and the USA

 

HS Code: 29349900 (for import/export classification)

Additional Information:

• Item Code: 29349900
• Port of Dispatch: INDIA
• Production Capacity: 20 MT
• Delivery Time: PROMPT
• Packaging Details: DRUM

Product Details:

 

We are offering high quality of Levetiracetam. We are known for manufacturing, exporting, distributing, trading and supplying Levetiracetam in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Levetiracetam in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Levetiracetam. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Levetiracetam as well as Intermediates of Levetiracetam.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Levetiracetam to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Levetiracetam API Powder – Detailed Description

 General Information

Product Name: Levetiracetam API Powder

Chemical Name: (S)-α-Ethyl-2-oxo-1-pyrrolidineacetamide

Molecular Formula: C₈H₁₄N₂O₂

Molecular Weight: 170.21 g/mol

CAS Number: 102767-28-2

Appearance: White to off-white crystalline powder

 Properties

Solubility: Soluble in water and freely soluble in chloroform, methanol, and ethanol

Melting Point: 115-119°C

Purity: ≥ 99% (typically tested via HPLC)

Storage Conditions: Store in a cool, dry place, away from moisture and direct sunlight

Shelf Life: 2–3 years when stored properly

Uses & Applications

Levetiracetam is a broad-spectrum anticonvulsant drug used primarily to treat:

Epilepsy (partial-onset seizures, myoclonic seizures, and tonic-clonic seizures)

Seizure disorders in adults and children

Off-label applications in neuropathic pain, migraine prevention, and psychiatric disorders

Mechanism of Action

Levetiracetam acts by binding to the synaptic vesicle protein 2A (SV2A) in the brain, which helps regulate neurotransmitter release and stabilizes neuronal activity, reducing the frequency of seizures.

Manufacturing & Quality Standards

GMP Compliance: Manufactured under Good Manufacturing Practices (GMP)

Pharmacopoeial Standards: Meets USP/BP/EP specifications

Testing Methods: HPLC, IR, and NMR analysis to ensure purity and stability

Safety & Handling

Toxicity: Low toxicity; however, excessive doses can cause dizziness, somnolence, and behavioral changes

Precautions: Use with caution in patients with kidney disorders, psychiatric conditions, or pregnancy

Packaging: Usually packed in double-layer PE bags or fiber drums (25 kg per drum)

 

 

Additional Information:

• Delivery Time: prompt
• Packaging Details: Drum

Product Details:

We are offering high quality of Nikethamide Api. We are known for manufacturing, exporting, distributing, trading and supplying Nikethamide Api   in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Nikethamide Api   in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Nikethamide Api . Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Nikethamide Api as well as Intermediates of Nikethamide Api.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Nikethamide Api to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Nikethamide is a stimulant which mainly affects the respiratory cycle. Widely known by its former trade name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overdoses, before the advent of endotracheal intubation and positive-pressure lung expansion.

1. General Information-Product Name: Nikethamide API Powder, Chemical Name: Nikethamide, IUPAC Name: N,N-Diethyl-3-pyridinecarboxamide, CAS Number: 59-26-7, Molecular Formula: C₁₀H₁₄N₂O, Molecular Weight: 178.23 g/mol,Appearance: White to off-white crystalline powder, Odor: Odorless or faint characteristic odor, Solubility: Soluble in water, ethanol, chloroform, and slightly soluble in ether

2. Physical & Chemical Properties, Melting Point: 92-95°C, Boiling Point: Decomposes before boiling

Density: ~1.1 g/cm³, pH (Solution): Neutral to slightly acidic

Stability: Stable under normal storage conditions, but decomposes at high temperatures

3. Pharmacological Information: Nikethamide acts as a central nervous system (CNS) stimulant, primarily affecting the medulla oblongata, which controls respiration.

Absorption: Rapidly absorbed when administered orally or via injection.

Metabolism: Metabolized in the liver, Excretion: Excreted primarily via urine, Medical Uses (Historical & Limited Current Use):Used in the past as a respiratory stimulant for treating:

4. Applications & Industrial Uses

Pharmaceutical Industry: Used as an Active Pharmaceutical Ingredient (API) in respiratory stimulants.

Limited use in experimental neurostimulation research.

Veterinary Applications: Previously used in some animal treatments for respiratory depression.

Sports & Performance Enhancement:

5. Safety, Toxicity & Side Effects: Low to moderate toxicity but can be dangerous in high doses.

Can cause seizures, convulsions, nausea, anxiety, tremors, arrhythmia, and even respiratory failure.

Side Effects: Increased heart rate, restlessness, headache, dizziness.

High doses may lead to convulsions or cardiovascular complications.

6. Handling & Storage:Avoid inhalation, ingestion, and skin contact.

Use personal protective equipment (PPE) when handling.

Storage Conditions: Store in a cool, dry, and well-ventilated area.

Keep away from direct light, heat, and moisture.

Recommended storage temperature: 2-8°C (refrigerated) or below 25°C (controlled room temperature).

Shelf Life: Typically 24-36 months under proper storage conditions.

Additional Information:

• Item Code: 3004
• Delivery Time: prompt
• Packaging Details: 25kgs drum pack

Product Details:

We are offering high quality Amoxicillin Trihydrate. We are known for manufacturing, exporting, distributing, trading and supplying Amoxicillin Trihydrate in Gujarat India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Amoxicillin Trihydrate in Gujarat India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Amoxicillin Trihydrate.. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Amoxicillin Trihydrate as well as Intermediates of Amoxicillin Trihydrate.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Amoxicillin Trihydrate to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Amoxicillin Trihydrate Powder is a commonly used antibiotic in the penicillin class. It is the trihydrate form of amoxicillin, which is a broad-spectrum beta-lactam antibiotic effective against a wide range of bacterial infections. Here’s a detailed description of the compound:

Chemical Structure and Composition:

Name: Amoxicillin Trihydrate
Chemical Formula: C16H19N3O5 · 3H2O
Molecular Weight: Approximately 419.41 g/mol (including water of crystallization)
Appearance: It is a white to off-white crystalline powder, often hygroscopic (absorbs moisture from the air).

Physical Properties:
Solubility: Amoxicillin Trihydrate is highly soluble in water and has good solubility in polar solvents. This is why it is often formulated in liquid forms such as syrups or oral suspensions.
Melting Point: The melting point of amoxicillin trihydrate is around 200–210°C, but this can vary slightly based on its crystalline form.

Uses and Indications:
Infections Treated by Amoxicillin: Amoxicillin is used to treat a wide range of bacterial infections, including:
Respiratory tract infections (e.g., pneumonia, bronchitis),Urinary tract infections (e.g., cystitis, pyelonephritis),Ear infections (e.g., otitis media),Skin and soft tissue infections,Stomach ulcers caused by Helicobacter pylori (often in combination with other drugs),Gonorrhea,Endocarditis prophylaxis (to prevent infections before surgery)

Combination Therapy: Amoxicillin is sometimes used in combination with other antibiotics (e.g., clavulanic acid, in the form of amoxicillin/clavulanate) to overcome bacterial resistance mechanisms.

Dosage and Administration:
Amoxicillin Trihydrate is most commonly administered orally in the form of capsules, tablets, or oral suspension.
The dosage can vary based on the type of infection and patient characteristics 
Side Effects:Common Side Effects: Amoxicillin is generally well-tolerated, but some side effects may include:, Nausea, vomiting, diarrhea,Skin rash,Allergic reactions (e.g., hives, anaphylaxis, though rare),Abdominal pain

Serious Side Effects: Rare but severe reactions include:Liver toxicity,Hematological abnormalities (e.g., anemia, thrombocytopenia),Clostridium difficile-associated diarrhea (due to disruption of gut flora)
Contraindications and Cautions:
Contraindications: Amoxicillin should not be used in patients who are allergic to penicillin or other beta-lactam antibiotics.

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• Delivery Time: prompt
• Packaging Details: 25kgs drum pack

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We are offering high quality of Cefixime .We are known for manufacturing, exporting, distributing, trading and supplying Cefixime In Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Cefixime in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Cefixime Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Cefixime as well as Intermediates of Cefixime.Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Cefixime to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Introduction of product: Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall.
Technical specifications: - 
Synonyms  : Cefixima, Cefiximum, Cephoral, Cefspan,
Formula  : C₁₆H₁₅N₅O₇S₂Molecular Weight : 453.45

Storage 3 years -20°C powder
2 years -80°C in solvent
CAS No. : 79350-37-1
How to use :: Cefixime is used to treat a wide variety of bacterial infections. This medication is known as a cephalosporin antibiotic. It works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.
Dosage of usage : Adults : The recommended dose of cefixime is 400 mg daily. This may be given as a 400 mg tablet or capsule daily or the 400 mg tablet may be split and given as one half tablet every 12 hours. For the treatment of uncomplicated cervical/urethral gonococcal infections, a single oral dose of 400 mg is recommended. The capsule and tablet may be administered without regard to food.
Pediatric Patients (6 Months Or Older) : The recommended dose is 8 mg/kg/day of the suspension. This may be administered as a single daily dose or may be given in two divided doses, as 4 mg/kg every 12 hours.
Side effects :: Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.Call your doctor at once if you have:severe stomach pain, diarrhea that is watery or bloody;jaundice (yellowing of the skin or eyes);
pale or yellowed skin, dark colored urine, confusion or weakness;a seizure (convulsions);
Common side effects may include:indigestion, stomach pain;nausea, vomiting; or vaginal itching or discharge.
Warnings and precautions while using this product : Call your doctor if your symptoms do not improve or if they get worse.Keep all medicine out of the reach of children. Never share your medicine with anyone.

Additional Information:

• Production Capacity: 1000
• Delivery Time: immediate
• Packaging Details: 25 kgs Drum Packing

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We are offering high quality of Doxylamine Succinate. We are known for manufacturing, exporting, distributing, trading and supplying Doxylamine Succinate in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Doxylamine Succinate in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Doxylamine Succinate . Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Doxylamine Succinate as well as Intermediates of Doxylamine Succinate.Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Doxylamine Succinate to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries
Doxylamine Succinate Powder is the active pharmaceutical ingredient (API) of doxylamine succinate, an antihistamine commonly used for its sedative properties. It is often employed for the treatment of insomnia, nausea, and other conditions such as allergic rhinitis and the common cold.
Description:
Chemical Name: (E)-N,N-Dimethyl-2-[(1-phenylpropan-2-yl)oxy]ethanamine succinate
Molecular Formula: C17H22N2O2 · C4H6O4
CAS Number: 556-66-9 (Doxylamine Succinate)
Appearance: Doxylamine Succinate Powder is typically a white to off-white crystalline powder, odorless or with a faint odor, and it is soluble in water and alcohol.
Uses:
Doxylamine Succinate Powder is used in a variety of therapeutic settings:
Allergic Conditions:
Allergic Rhinitis: Treatment of seasonal or perennial allergies.
Hay Fever: Doxylamine is used to treat symptoms like sneezing, itching, and a runny nose.
Insomnia:
Doxylamine is often used as a short-term sleep aid to help individuals with trouble falling or staying asleep due to its sedative effects.
Nausea and Vomiting:
It can be used as part of combination therapy for treating nausea and vomiting during pregnancy (particularly in combination with vitamin B6, known as Diclegis or Bonjesta).
Common Cold Symptoms:
Doxylamine can be used to alleviate symptoms of the common cold, especially those involving nasal congestion, sneezing, and runny nose.
Dosage and Administration:
Oral Dosage: Doxylamine Succinate is typically formulated into tablets, liquids, or capsules for oral administration. The powder can be reconstituted into a liquid for oral use, but exact dosages should be followed according to the manufacturer or healthcare provider's directions.
Side Effects:
While doxylamine is generally well-tolerated, some side effects may occur:Dry Mouth, Throat, or Nose: Due to its anticholinergic effects.
Dizziness or Confusion: Especially in elderly individuals.
Constipation: A common side effect due to the anticholinergic properties.Blurred Vision: Due to its anticholinergic action.
Urinary Retention: Difficulty urinating can be a concern in some individuals, particularly those with prostate issues.
Storage:Storage Conditions: Doxylamine Succinate Powder should be stored in a cool, dry place at room temperature, away from moisture and direct light.
Purity:Purity: Pharmaceutical-grade Doxylamine Succinate should have a purity of at least 98%. It must meet the specifications for impurities and residual solvents as defined by pharmacopeial standards such as USP (United States Pharmacopeia) or EP 

Additional Information:

• Port of Dispatch: INDIA
• Production Capacity: 20 MT
• Delivery Time: PROMPT
• Packaging Details: DRUM

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We are offering high quality of Loratadine Api Powder. We are known for manufacturing, exporting, distributing, trading and supplying Loratadine Api Powder  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Loratadine Api Powder  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Loratadine Api Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Loratadine Api Powder as well as Intermediates of Loratadine Api Powder.   Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Loratadine Api Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Loperamide HCl Powder – Detailed Description

Chemical Information:

Chemical Name: Loperamide Hydrochloride

Molecular Formula: C29H34Cl2N2O2·HCl

Molecular Weight: 513.51 g/mol

CAS Number: 34552-83-5

Appearance: White or off-white crystalline powder

Solubility: Slightly soluble in water, freely soluble in methanol and ethanol

Melting Point: 214-220°C

Pharmacology & Mechanism of Action:

Loperamide HCl is an opioid receptor agonist that acts on the mu-opioid receptors in the intestines. It reduces gastrointestinal motility and fluid secretion, thereby increasing stool consistency and decreasing the frequency of bowel movements. Unlike other opioids, it has minimal central nervous system (CNS) effects because of poor blood-brain barrier penetration.

Uses & Applications:

Primarily used as an antidiarrheal agent for acute and chronic diarrhea.

Helps manage irritable bowel syndrome (IBS)-related diarrhea.

Used in some cases to reduce ostomy output.

Dosage & Administration:

The recommended adult initial dose for acute diarrhea is 4 mg, followed by 2 mg after each loose stool, not exceeding 16 mg/day.

For chronic diarrhea, doses are adjusted individually.

Side Effects & Precautions:

Common Side Effects: Constipation, nausea, abdominal cramps, dizziness.

Serious Side Effects: Cardiac arrhythmias (QT prolongation at high doses), toxic megacolon, CNS depression in overdose cases.

Contraindications:

Not for use in children under 2 years.

Avoid in infectious diarrhea caused by bacteria like Clostridium difficile.

Caution in patients with hepatic impairment.

Storage & Stability:

Store in a cool, dry place away from light and moisture.

Keep in tightly sealed containers to prevent degradation.

Regulatory & Safety Information:

Controlled Status: Available over-the-counter (OTC) in lower doses but prescription-strength formulations exist.

Toxicity Concern: High doses may lead to serious heart-related complications due to sodium and potassium channel interference.

 

Additional Information:

• Port of Dispatch: INDIA
• Production Capacity: 1 mt
• Delivery Time: PROMPT
• Packaging Details: DRUM

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We are offering high quality of Zinc Carnosine. We are known for manufacturing, exporting, distributing, trading and supplying Zinc Carnosine  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Zinc Carnosine  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Zinc Carnosine. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Zinc Carnosine as well as Intermediates of Zinc Carnosine.  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Zinc Carnosine to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
 
Zinc Carnosine is a compound consisting of zinc and carnosine, a dipeptide made up of the amino acids histidine and beta-alanine. This compound is used primarily in dietary supplements for digestive health due to its potential to support the gut lining and promote healing in the gastrointestinal tract. Zinc carnosine is known for its unique ability to help with the repair of the stomach lining, reducing inflammation, and supporting gut health.
Chemical Structure:
IUPAC Name: Zinc bis(carnosine)
Molecular Formula: C9H14N4O3Zn\text{C}_9 \text{H}_{14} \text{N}_4 \text{O}_3 \text{Zn}C9​H14​N4​O3​Zn
Molar Mass: Approximately 403.6 g/mol
Components:
Zinc (Zn): An essential trace mineral that is involved in numerous biological functions, including immune system support, cell division, DNA synthesis, and protein synthesis.
Carnosine: A naturally occurring dipeptide consisting of histidine and beta-alanine. Carnosine is a powerful antioxidant and has protective effects on tissues, particularly the stomach lining.
Mechanism of Action:
Gastroprotective Effect: Zinc carnosine supports the integrity of the gastrointestinal lining by enhancing the production of mucus and promoting the growth of intestinal cells. It helps in the repair of damaged cells and tissues in the stomach and intestines.
Antioxidant Properties: Carnosine, the peptide component of the compound, has potent antioxidant effects. It helps neutralize free radicals in the stomach, protecting cells from oxidative stress and damage.
Anti-inflammatory Effects: Zinc carnosine has been shown to have anti-inflammatory effects, which can be beneficial for conditions such as gastritis or ulcers, where inflammation plays a major
Safety and Dosage:
Recommended Dosage: The typical recommended dosage of zinc carnosine ranges from 75 mg to 150 mg per day, often taken in divided doses.
Safety: Zinc carnosine is generally considered safe when taken in recommended amounts. However, high doses of zinc can lead to side effects, such as nausea, vomiting, and impaired immune function. It’s important to stick to the recommended dosage to avoid exceeding the upper tolerable intake levels of zinc.
Side Effects: Most individuals tolerate zinc carnosine well, but as with any supplement, gastrointestinal side effects (such as mild nausea or stomach upset) may occur in some people. If these symptoms persist, it is advisable to consult a healthcare professional. 

Additional Information:

• Delivery Time: Prompt
• Packaging Details: 25 KG HDPE Drum

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We are offering high quality of CLOMIFENE CITRATE We are known for manufacturing,exporting, distributing, trading and supplying CLOMIFENE CITRATE in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of CLOMIFENE CITRATE in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of CLOMIFENE CITRATE Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing CLOMIFENE CITRATE as well as Intermediates of CLOMIFENE CITRATEShreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export CLOMIFENE CITRATE to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Clomifene Citrate (also known as Clomid or Serophene) is a medication primarily used to treat female infertility. It works by stimulating ovulation, the release of an egg from the ovary. Here's a detailed breakdown of its uses, mechanisms, and other relevant information:
What is Clomifene Citrate?
Clomifene Citrate is a synthetic, non-steroidal fertility drug. It is commonly prescribed to women who are struggling with ovulatory dysfunction, which means they have difficulty ovulating (releasing eggs from the ovaries). Clomifene can also be used for men in certain situations, particularly to improve sperm production in cases of hypogonadism (low levels of testosterone).
Mechanism of Action
Clomifene Citrate works as a selective estrogen receptor modulator (SERM). It interferes with estrogen’s action in the hypothalamus (a part of the brain), which is responsible for regulating hormones that control ovulation. The hypothalamus senses low estrogen levels and, in response, releases more gonadotropin-releasing hormone (GnRH), which stimulates the pituitary gland to release follicle-stimulating hormone (FSH) and luteinizing hormone (LH). These hormones help stimulate the ovaries to produce eggs, thus promoting ovulation.
By blocking estrogen receptors in the brain, Clomifene Citrate effectively "tricks" the body into thinking there is insufficient estrogen, prompting it to release more FSH and LH, which increases the chances of ovulation.
Uses
Female Infertility: Clomifene is most commonly used to treat women who have anovulatory cycles (where ovulation doesn’t occur) or irregular ovulation. It is often used for conditions like:
Polycystic ovary syndrome (PCOS): Women with PCOS often have irregular or absent ovulation.
Hypothalamic amenorrhea: When the hypothalamus fails to trigger ovulation.
Male Infertility: In some cases, Clomifene may be prescribed for men to treat hypogonadotropic hypogonadism, a condition where the body doesn’t produce enough gonadotropins (FSH and LH), leading to low sperm count or infertility.
Dosage and Administration
The usual starting dose for Clomifene Citrate in women is 50 mg per day for five days, typically taken during the first 5 days of the menstrual cycle. If ovulation doesn’t occur after the first cycle, the dose can be increased (up to 150 mg per day) in subsequent cycles.
The drug is typically taken orally in pill form.
Side Effects
Clomifene Citrate is generally well tolerated, but some side effects may occur. Common side effects include:
Hot flashes
Mood swings
Bloating
Breast tenderness
Headaches
Less common but more serious side effects include:

Additional Information:

• Delivery Time: prompt
• Packaging Details: 25kgs

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We are offering high quality of Amitriptyline. We are known for manufacturing, exporting, distributing, trading and supplying Amitriptyline. in Gujarat India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Amitriptyline in Gujarat India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Amitriptyline.. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Amitriptyline as well as Intermediates of Amitriptyline.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Amitriptyline to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Amitriptyline is a tricyclic antidepressant (TCA) that is commonly used to treat depression, neuropathic pain, migraines, and certain anxiety disorders. It works by increasing the levels of neurotransmitters like serotonin and norepinephrine in the brain.

Physical and Chemical Properties:

Appearance: White to off-white crystalline powder
Molecular Formula: C₂₀H₂₃N
Molecular Weight: 277.40 g/mol
Solubility:
Slightly soluble in water
Freely soluble in ethanol and methanol
Soluble in chloroform and other organic solvents
Melting Point: Approximately 195-197°C
Stability: Stable under normal storage conditions, but sensitive to light and moisture
Pharmacological Properties:

Metabolism: Primarily metabolized in the liver via CYP2D6 enzyme
Excretion: Mostly excreted in urine

Common Uses:Treatment of major depressive disorder (MDD)
Neuropathic pain (e.g., diabetic neuropathy, postherpetic neuralgia)
Prevention of migraines and chronic headaches
Fibromyalgia and other chronic pain conditions
Insomnia (off-label use)

Precautions: Avoid inhalation, ingestion, and skin contact; handle with gloves and protective gear in laboratory settings
Toxicity: Overdose may cause severe side effects, including cardiac arrhythmias, seizures, and central nervous system depression
Amitriptyline is a tricyclic antidepressant primarily used to treat depression, nerve pain, and migraines. When used in powder form (compounded or raw form), it carries the same risks as its tablet version. Below are the side effects and precautions associated with amitriptyline.

Side Effects of Amitriptyline Powder: Side effects can range from mild to severe, depending on the dosage and individual tolerance.

Common Side Effects (Usually temporary):Drowsiness or sedation,Dry mouth,Dizziness or lightheadedness,Constipation,Blurred vision,Weight gain,Increased sweating,Difficulty urinating
Serious Side Effects (Seek medical attention):Irregular or fast heartbeat (arrhythmia),Severe dizziness or,fainting,Seizures,Hallucinations or confusion,Difficulty breathing,Uncontrollable shaking (tremors),Severe allergic reaction (rash, swelling, difficulty breathing),Suicidal thoughts (especially in young adults)

Precautions When Using Amitriptyline Powder
Before Use: Medical History – Inform your doctor if you have:Heart disease or irregular heartbeat,Seizures or epilepsy,Liver or kidney disease,Glaucoma,Bipolar disorder or,schizophrenia,Urinary retention issuesr.

Additional Information:

• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: INDIA
• Production Capacity: 20 MT
• Delivery Time: PROMPT
• Packaging Details: DRUM

Product Details:

 

 

We are offering high quality Bisacodyl.We are known for manufacturing, exporting, distributing, trading and supplying Bisacodyl in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Bisacodyl in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Bisacodyl Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing  Biperiden HCL as well as Intermediates of Bisacodyl.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Bisacodyl to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Bisacodyl Powder is a stimulant laxative used to treat constipation. It works by stimulating the muscles in the colon to promote bowel movement, making it easier to pass stool. It is available in various forms, including tablets, suppositories, and powders, with the powder form often used for reconstitution into a solution for oral or rectal administration.

Name: Bisacodyl

IUPAC Name: 4-(p-chlorobenzoyl)-1-(2,5-dihydroxyphenyl)-2-pyrrolidinyl) butan-1-one

Molecular Formula: C22H19ClO4

Molecular Weight: 361.84 g/mol

Physical Characteristics:

Appearance: White or almost white, crystalline powder.

Solubility: Slightly soluble in water, more soluble in alcohol and organic solvents.

Odor: Odorless or nearly odorless.

Side Effects and Adverse Reactions:

Common Side Effects:Abdominal cramps or discomfort,Diarrhea,Nausea,Bloating or gas
Serious Side Effects:Electrolyte imbalances (especially with prolonged use)

Dehydration due to excessive loss of water from the bowel

Severe abdominal pain or persistent diarrhea ,Rectal irritation (with suppositories or enema use)

Precautions:Should not be used in cases of bowel obstruction, ileus, or acute abdominal conditions.Long-term use can lead to dependence on laxatives, so Bisacodyl should be used only for short-term relief.Caution in patients with heart disease or electrolyte disturbances due to the risk of dehydration.

Bisacodyl Powder is an effective stimulant laxative that helps to relieve constipation and is also used in bowel preparation for medical procedures. It works by stimulating the muscles of the colon and increasing fluid secretion, promoting easier bowel movements. However, like all stimulant laxatives, it should be used with caution, especially for long-term treatment, as prolonged use can lead to dependence or electrolyte imbalances.

Dosage and Administration:

Oral Use:Bisacodyl powder is often mixed with water to make a solution for oral administration.

Adult Dose: 5–10 mg once daily, typically taken at bedtime to produce a bowel movement the next morning.
The powder is dissolved in a recommended volume of water or liquid to form an oral solution.

Rectal Use (for bowel preparation or severe constipation):
When used for rectal administration, the powder is typically dissolved in a small amount of water and used as an enema or suppository. Dosage varies depending on the specific need.

 

 

Additional Information:

• Delivery Time: PROMPT
• Packaging Details: DRUM

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We are offering high quality of Amlodipine Besylate. We are known for manufacturing, exporting, distributing, trading and supplying Amlodipine Besylate. in Gujarat India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Amlodipine Besylate in Gujarat India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Amlodipine Besylate.. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Amlodipine Besylate as well as Intermediates of Amlodipine Besylate.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Amitriptyline to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

. General Information:

Generic Name: Amlodipine Besylate

Drug Class: Calcium Channel Blocker (Dihydropyridine type)

Common Brand Names: Norvasc, Amlip, Amlogard

Route of Administration: Oral (tablet)

2. Uses:Amlodipine Besylate is primarily used for:

Hypertension (High Blood Pressure): Helps lower blood pressure, reducing the risk of strokes, heart attacks, and kidney problems.

Angina (Chest Pain): Relaxes blood vessels to improve blood flow and oxygen delivery to the heart, reducing chest pain.

Coronary Artery Disease (CAD): Used to prevent complications related to blocked heart arteries.

3. Mechanism of Action:

Amlodipine Besylate works by inhibiting calcium influx into vascular smooth muscle and cardiac muscle cells. This action results in:

Vasodilation (widening of blood vessels)

Decreased blood pressure

Reduced workload on the heart

4. Dosage and Administration:

Common Dosages: 2.5 mg, 5 mg, and 10 mg tablets

Typical Adult Dose:

Hypertension & Angina: 5 mg once daily (may be increased to 10 mg if needed)

Elderly or Liver-Impaired Patients: Start with 2.5 mg

Pediatric Dose (ages 6-17): 2.5 mg to 5 mg once daily

5. Side Effects:

Common Side Effects:Dizziness

Swelling (edema) in the ankles or feet,Fatigue,Flushing,Headache,Serious Side Effects (Rare):,Irregular heartbeat,Severe dizziness or fainting,Shortness of breath,Chest pain (worsening angina)

6. Warnings & Precautions:Liver Disease: May require lower doses

Heart Failure: Can cause fluid retention

Pregnancy & Breastfeeding: Use only if necessary (consult a doctor)

Alcohol Use: May increase dizziness

7. Drug Interactions:Beta-blockers (e.g., Metoprolol, Atenolol): May cause excessive blood pressure reduction

Grapefruit Juice: May increase drug levels and side effects

CYP3A4 Inhibitors (e.g., Ketoconazole, Ritonavir): Can increase Amlodipine levels

NSAIDs (e.g., Ibuprofen, Naproxen): May reduce blood pressure-lowering effects

8. Storage:Store at room temperature (20°C-25°C or 68°F-77°F)

Keep away from moisture and heat

Additional Information:

• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: India
• Production Capacity: 20mt
• Delivery Time: prompt
• Packaging Details: Drum

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We are offering high quality of  DomperidoneWe are known for manufacturing,exporting, distributing, trading and supplying Domperidone Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Domperidone in Gujarat. India. Shreeji Pharma International manufacturing & suppling all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Domperidone Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Domperidone as well as Intermediates of  Domperidone.Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Domperidone to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries
Domperidone Maleate is an antiemetic and gastroprokinetic medication commonly used to treat nausea, vomiting, and gastroparesis (delayed stomach emptying). It works by blocking dopamine receptors in the gut and brain, promoting motility in the stomach and intestines and reducing nausea.
Description:
Chemical Name: (E)-1-[(3-Chlorophenyl)methyl]-4-(1-pyrrolidinylmethyl)-2,3-dihydro-1H-benzimidazol-2-one maleate
Molecular Formula: C22H24ClN5O2 · C4H4O4
CAS Number: 57808-48-5 (Domperidone) and 600-73-9 (Maleate salt)
Appearance: Domperidone Maleate appears as a white to off-white crystalline powder that is odorless or has a very faint odor.
Uses: Nausea and Vomiting: It is widely used to treat nausea and vomiting, particularly when they are associated with gastrointestinal disorders or medications that induce nausea.
Gastroparesis: Domperidone Maleate is used in the treatment of gastroparesis, a condition where the stomach empties too slowly, causing nausea, vomiting, and bloating.
Reflux Esophagitis: It can help treat reflux symptoms (e.g., acid reflux, GERD) by promoting gastric emptying and preventing acid regurgitation.
Post-surgical Nausea: It may be used to manage nausea following abdominal surgery.
Dosage and Administration:
Oral Dosage: Domperidone Maleate powder is often formulated into tablets or oral suspensions. However, when used as a powder, it may be reconstituted into a solution for oral administration.
Adults: The typical dosage for adults ranges from 10 mg to 20 mg taken 3 to 4 times daily before meals, with a maximum recommended dose of 80 mg per day.
Children: The dosage for children is based on body weight and should be carefully determined by a healthcare provider.
Intravenous Use: Domperidone is typically not available in injectable form in many countries. However, if it is used in hospital settings, intravenous administration might be prescribed in severe cases under strict medical supervision.
Side Effects:Common side effects of Domperidone Maleate include:
Dry mouth , Abdominal cramps or discomfort ,Diarrhea ,Headache
Dizziness
More severe side effects (though rare) may include:
Extrapyramidal Symptoms (EPS): These include involuntary muscle movements, tremors, or rigidity, though these are uncommon with Domperidone compared to other dopamine antagonists.
Cardiac Issues: QT prolongation (a heart rhythm disorder) may occur in some patients, especially in those with pre-existing heart conditions. 
Purity:Purity: Domperidone Maleate is required to have a purity of ≥ 98% to meet pharmaceutical quality standards.

Additional Information:

• Item Code: 29225024
• Production Capacity: production capacity of 200 MT/Month
• Delivery Time: Prompt
• Packaging Details: 25 Kgs Drum Packing

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We are offering high quality of Chloroquine Phosphate. We are known for manufacturing, exporting, distributing, trading and supplying Chloroquine Phosphate in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of  Chloroquine Phosphate in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Chloroquine Phosphate Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Chloroquine Phosphate as well as Intermediates of Chloroquine Phosphate.Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Chloroquine Phosphate  to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Chloroquine Phosphate is a medication primarily used to prevent and treat malaria, and it has been used for other conditions as well, such as autoimmune diseases like rheumatoid arthritis and lupus. It is the phosphate salt form of chloroquine, a synthetic compound derived from the bark of the cinchona tree, which was historically used to treat malaria.
Uses
Malaria Treatment and Prevention: Chloroquine phosphate is effective against Plasmodium species, which are responsible for malaria. It works by interfering with the parasite's ability to break down hemoglobin in red blood cells. It is used for the treatment of uncomplicated malaria caused by Plasmodium falciparum, Plasmodium malariae, Plasmodium ovale, and Plasmodium vivax. It is also used as a prophylactic to prevent malaria in areas where chloroquine resistance is not common.
Autoimmune Disorders: Chloroquine phosphate is used to treat autoimmune conditions like rheumatoid arthritis and lupus erythematosus. It is believed to work by modulating immune system activity, reducing inflammation, and preventing tissue damage.
Other Potential Uses:
In some cases, chloroquine has been explored for its potential antiviral properties, notably for viruses like COVID-19, although its efficacy for this purpose has been debated.
It has also been studied for the treatment of certain skin diseases like porphyria cutanea tarda.
Mechanism of Action
Chloroquine works by accumulating in the parasite's food vacuole, where it interferes with the parasite's ability to degrade hemoglobin. The compound then accumulates in the vacuole and raises the pH, which inhibits the breakdown of hemoglobin, leading to the death of the malaria parasite. In autoimmune diseases, chloroquine is believed to affect the immune system, possibly by inhibiting the production of certain cytokines and interfering with antigen processing.
Dosage and Administration
The dosage varies depending on the condition being treated:
For malaria prevention: Typically taken once a week, starting 1-2 weeks before traveling to an area where malaria is common, and continuing for 4 weeks after returning.
For malaria treatment: Usually administered as a 3-day course of treatment, but the specific dose depends on the severity of the disease and the species of Plasmodium involved.
For autoimmune diseases: The dose is often lower than for malaria, typically taken daily or weekly depending on the severity of the disease.

 

Additional Information:

• Delivery Time: Prompt
• Packaging Details: HDPE Drum

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We are offering high quality of Levocetirizine Dihydrochloride Powder. We are known for manufacturing, exporting, distributing, trading and supplying Levocetirizine Dihydrochloride Powder  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Levocetirizine Dihydrochloride Powder in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Levocetirizine Dihydrochloride Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Levocetirizine Dihydrochloride Powder as well as Intermediates of Levocetirizine Dihydrochloride Powder.   Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Levocetirizine Dihydrochloride Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries. Levocetirizine Dihydrochloride Powder (also known as Levocetirizine Dihydrochloride Powder) is a medication primarily used to treat respiratory conditions such as asthma, chronic obstructive pulmonary disease (COPD), and bronchospasms. It belongs to the class of bronchodilators, which help relax the muscles in the airways and improve airflow to the lungs.

Levocetirizine Dihydrochloride Powder – Detailed Description

General Information:

Chemical Name: Levocetirizine Dihydrochloride

Molecular Formula: C21H25ClN2O3·2HCl

Molecular Weight: 461.82 g/mol

CAS Number: 130018-87-0

Chemical Structure: It is the active R-enantiomer of cetirizine, classified as a third-generation non-sedative antihistamine.

Physical and Chemical Properties:

Appearance: White or almost white crystalline powder

Solubility: Freely soluble in water, sparingly soluble in ethanol, and practically insoluble in acetone

Melting Point: Approximately 215-220°C

Stability: Stable under recommended storage conditions, sensitive to light and moisture

Pharmacological Information:

Mechanism of Action:
Levocetirizine is an H₁ receptor antagonist that blocks histamine activity, reducing allergic symptoms like sneezing, runny nose, and itching. It has a high affinity for H₁ receptors and minimal penetration of the blood-brain barrier, reducing sedative effects.

Uses & Indications:

Allergic rhinitis (seasonal and perennial)

Chronic idiopathic urticaria (hives)

Hay fever

Skin allergies

Dosage & Administration:

Typically used in tablet or syrup form, but powder may be used for formulation.

Usual adult dose: 5 mg per day (or as prescribed).

Side Effects:

Drowsiness (less common than older antihistamines)

Dry mouth

Fatigue

Headache

Nausea

Precautions & Warnings:

Avoid use with alcohol or CNS depressants.

Use cautiously in patients with renal impairment.

 

Not recommended for children under 6 months without medical advice.

Storage Conditions:

Store in a cool, dry place away from light and moisture.

Recommended storage temperature: 15°C to 30°C.

 

 

Additional Information:

• Port of Dispatch: INDIA
• Production Capacity: 20 MT
• Delivery Time: PROMPT
• Packaging Details: Packed in 25 Kgs HDPE Drums

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We are offering high quality of Venlafaxine Hcl. We are known for manufacturing, exporting, distributing, trading and supplying Venlafaxine Hcl  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Venlafaxine Hcl  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Venlafaxine Hcl. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Venlafaxine Hcl as well as Intermediates of Venlafaxine Hcl.  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Venlafaxine Hcl to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
 
Venlafaxine Hydrochloride (HCl) is a prescription medication primarily used to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder (SAD), and panic disorder. It is classified as a serotonin-norepinephrine reuptake inhibitor (SNRI). This class of medication works by increasing the levels of two important neurotransmitters in the brain—serotonin and norepinephrine—which help regulate mood and emotions.
General Information:
Chemical Name: (R,S)-1-[2-(dimethylamino)ethyl]-1-(4-methoxyphenyl)-3-(trifluoromethyl)phenyl)propan-2-ol hydrochloride.
Molecular Formula: C17H27NO2•HCl.
CAS Number: 93413-69-5.
Brand Names: Effexor XR (extended-release form), Effexor (immediate-release form).
Drug Class: Serotonin-norepinephrine reuptake inhibitor (SNRI).
Mechanism of Action:
Venlafaxine works by inhibiting the reuptake of two key neurotransmitters in the brain: serotonin and norepinephrine. By blocking the reuptake of these neurotransmitters, venlafaxine increases their availability in the brain, which helps to improve mood and reduce feelings of anxiety. It is thought to have a dual action—at lower doses, venlafaxine primarily increases serotonin levels, and at higher doses, it also increases norepinephrine levels.
Serotonin: Helps regulate mood, sleep, and anxiety.
Norepinephrine: Affects attention, alertness, and stress response.
Uses:
Venlafaxine is prescribed for the treatment of several mental health conditions:
Major Depressive Disorder (MDD): Venlafaxine is commonly used to treat depression, helping to reduce feelings of sadness, hopelessness, and disinterest in activities.
Generalized Anxiety Disorder (GAD): It helps alleviate excessive worry, restlessness, and physical symptoms associated with generalized anxiety.
Social Anxiety Disorder (SAD): Venlafaxine is effective in treating the fear of social situations and the distress caused by social interactions.
Panic Disorder: It is used to reduce the frequency and severity of panic attacks, which are sudden episodes of intense fear or discomfort.

Additional Information:

• Port of Dispatch: INDIA
• Production Capacity: 20 MT
• Delivery Time: PROMPT
• Packaging Details: DRUM

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We are offering high quality of Itraconazole Powder. We are known for manufacturing, exporting, distributing, trading and supplying Itraconazole Powder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Itraconazole Powder in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Itraconazole Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Itraconazole Powder  as well as Intermediates of Itraconazole Powder  is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Itraconazole Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Itraconazole is an antifungal medication commonly used to treat various fungal infections. Here are the technical details about Itraconazole:

1. Chemical Properties

IUPAC Name: (2R,4S)-1-[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1H-imidazol-1-yl]-3-(propan-2-yl)-2,4-dihydroxybutyl]-5-methyl-4-phenylthiazol-2-ylmethyl)-2,4-dihydroxybutyl]-5-methyl-4-phenylthiazol

Molecular Formula: C35H38Cl2N8O4S

Molecular Weight: 705.7 g/mol

Melting Point: Around 170-175°C

Solubility: Practically insoluble in water; soluble in methanol, ethanol, and DMSO.

1.  Indications: Itraconazole is used to treat a variety of fungal infections, including:

Aspergillosis (a type of lung infection caused by Aspergillus species)

Blastomycosis (a fungal infection of the lungs and other organs)

Coccidioidomycosis (valley fever)

Histoplasmosis (another fungal infection of the lungs)

Onychomycosis (fungal infection of the nails)

Candidiasis (a yeast infection, including oral and esophageal candidiasis)

Dermatophyte infections (fungal infections of the skin, hair, and nails)

2.  Forms and Dosage:

Oral Tablets/Capsules: Typically, itraconazole is taken as oral tablets or capsules, with the specific dosage varying based on the infection being treated.

Oral Solution: A liquid form is available, often used for certain conditions like esophageal candidiasis or in patients who have difficulty swallowing tablets.

Intravenous Form: In more severe cases or hospitalized patients, itraconazole can be administered intravenously.

3.  Common Dosage Regimens:

For treating onychomycosis (nail fungal infections), itraconazole is often prescribed in pulse dosing, where patients take high doses for a week followed by a break, repeating the cycle over a period of months.

For other fungal infections, the dosage may vary from daily to weekly, depending on the severity of the infection and the specific fungal organism involved.

4. Side Effects: Common side effects of itraconazole include:

Nausea and vomiting

Diarrhea

Stomach pain

Headache

Dizziness

Rash

Liver enzyme changes (which may lead to liver damage in rare cases)

Swelling in the legs or feet (edema)

Severe side effects may include:

Liver toxicity or failure (monitoring of liver function is important during treatment)

 

 

Additional Information:

• Delivery Time: PROMPT
• Packaging Details: HDPE DRUM PACK