Active Pharmaceuticals Ingredients 1

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We are offering high quality of Promethazine Hcl. We are known for manufacturing, exporting, distributing, trading and supplying Promethazine Hcl  in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Promethazine Hcl  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Promethazine Hcl. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Promethazine Hcl as well as Intermediates of Promethazine Hcl.  Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Promethazine Hcl to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.Promethazine Hydrochloride (Promethazine HCl) is a medication used to treat a variety of conditions, including allergic reactions, nausea, vomiting, motion sickness, and sleep disorders. It is classified as an antihistamine, but it also possesses sedative, antiemetic (anti-nausea), and anticholinergic properties. Below is a detailed description of Promethazine HCl:

Name: Promethazine HydrochlorideChemical Formula: C17H20N2S·HClMolecular Weight: 320.88 g/molIUPAC Name: 10-(3-dimethylaminopropyl) phenothiazine hydrochlorideAppearance: Promethazine HCl is typically a white to off-white crystalline powder.Solubility: It is freely soluble in water and alcohol, but slightly soluble in chloroform and ether.Melting Point: Approximately 180-183°C (decomposes).pH: When dissolved in water, the pH is usually between 4.5 and 5.5 for an injectable solution.Uses:Promethazine HCl is widely used for a variety of medical purposes, including:Allergic Reactions: It can be used to treat symptoms of hay fever, rhinitis, and other allergic conditions by blocking the effects of histamine.Motion Sickness: Promethazine is often prescribed for the prevention and treatment of nausea and vomiting associated with motion sickness.Nausea and Vomiting: It is commonly used to prevent and treat nausea and vomiting caused by anesthesia, surgery, or chemotherapy.Sedation: Due to its sedative effects, it can be used as a short-term sleep aid or for its calming effects.Preoperative Sedation: In the medical setting, it is used as a sedative before and after surgery to reduce anxiety and prevent nausea.Cough and Cold Relief: Sometimes, it is used in combination with other medications to treat symptoms of the common cold or flu.Promethazine works by blocking the action of histamine at the H1 receptor site. Histamine is a chemical in the body that is responsible for allergic symptoms like itching, swelling, and runny nose. By blocking histamine, promethazine alleviates these symptoms. Additionally, its sedative properties are due to its ability to cross the blood-brain barrier and depress the central nervous system.Promethazine also has anticholinergic effects, which means it blocks the action of acetylcholine, a neurotransmitter involved in various body functions, including muscle movement and secretions. This contributes to its antiemetic (anti-nausea) effects and can help reduce motion sickness symptoms.Dosage and Administration:Promethazine HCl is available in several forms, including oral tablets, syrup, and injectable forms.Oral Tablets: Promethazine is typically prescribed in 12.5 mg, 25 mg, or 50 mg tablets. The usual dose depends on the condition being treated and the patient's response. 

 

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• Delivery Time: prompt
• Packaging Details: 25Kgs DRUM PACKING

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We are offering high quality of Tolvaptan. We are known for manufacturing, exporting, distributing, trading and supplying Tolvaptan  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Tolvaptan  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Tolvaptan. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Tolvaptan as well as Intermediates of Tolvaptan.  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Tolvaptan to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
 
Tolvaptan is a vasopressin receptor antagonist used to treat conditions like hyponatremia (low sodium levels in the blood) and autosomal dominant polycystic kidney disease (ADPKD). It works by blocking the effects of vasopressin, a hormone responsible for regulating water balance in the body, thereby promoting the excretion of excess water and helping maintain proper fluid balance.
Description & Properties:
Chemical Name: (1S,4R)-1-[(3,4-dichlorophenyl)methyl]-4-[(3S)-1-pyrrolidinylmethyl]-2-oxo-3-phenyl-1,3-dihydro-2H-imidazol-4-yl]methanol
Chemical Formula: C26H25Cl2N3O2
Molecular Weight: 464.41 g/mol
Appearance: White to off-white crystalline powder.
Solubility: Slightly soluble in water, more soluble in ethanol and other organic solvents.
Melting Point: Approximately 157–161°C.
Tolvaptan is typically available in oral tablet form for the treatment of hyponatremia and ADPKD.
Uses:
Hyponatremia: Tolvaptan is prescribed for the treatment of hyponatremia (low sodium levels) caused by conditions such as congestive heart failure, syndrome of inappropriate antidiuretic hormone secretion (SIADH), or other causes of fluid overload.
Autosomal Dominant Polycystic Kidney Disease (ADPKD): It is used in patients with ADPKD to slow kidney function decline by reducing cyst growth and improving fluid balance.
ADPKD Treatment: Tolkaptan has been shown to reduce the rate of kidney volume increase and the progression of kidney damage in patients with ADPKD. It is most effective in early stages of the disease.
Dosage and Administration:
Tolvaptan is taken orally and the dosage is usually adjusted based on the condition being treated.
Precautions:
Liver Function Monitoring: Due to the risk of liver toxicity, regular liver function tests are required during treatment. Tolvaptan is contraindicated in patients with liver disease, such as cirrhosis.
Fluid and Electrolyte Balance: Adequate hydration must be maintained, especially in the early stages of treatment, to prevent dehydration or severe electrolyte imbalances. Patients should be monitored regularly for changes in sodium, potassium, and other electrolytes.
Renal Function: In patients with impaired renal function, careful monitoring is required since excessive diuresis could worsen kidney function.
Storage:
Storage Conditions: Tolvaptan should be stored in a cool, dry place at room temperature, between 20°C to 25°C (68°F to 77°F).
Shelf Life: Keep in its original packaging, and do not use the medication beyond the expiration date printed on the packaging.

 

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• Item Code: 150683-30-0
• Production Capacity: 1 mt
• Delivery Time: Prompt
• Packaging Details: 25 kgs drums

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We are offering high quality of Phenylephrine Hydrochloride. We are known for manufacturing, exporting, distributing, trading and supplying Phenylephrine Hydrochloride in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Phenylephrine Hydrochloride in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Phenylephrine Hydrochloride. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Phenylephrine Hydrochloride as well as Intermediates of Phenylephrine Hydrochloride.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Phenylephrine Hydrochloride to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Chemical Information

Chemical Name: Phenylephrine Hydrochloride

CAS Number: 61-76-7

Molecular Formula: C₉H₁₄ClNO₂

Molecular Weight: 203.67 g/mol

Synonyms: Meta-sympatol, L-Phenylephrine HCl, Phenylephrine Monohydrochloride

Physical Properties

Appearance: White to off-white crystalline powder

Solubility: Highly soluble in water and ethanol, slightly soluble in chloroform, insoluble in ether

Melting Point: ~143°C - 145°C

pH (1% solution): 4.5 - 6.5

Pharmacological Action

Phenylephrine Hydrochloride is a selective α1-adrenergic receptor agonist, primarily used for its vasoconstrictive and decongestant properties. It increases blood pressure and reduces swelling by constricting blood vessels.

Uses & Applications

Nasal Decongestant

Found in over-the-counter (OTC) cold and flu medications

Helps relieve nasal congestion caused by colds, allergies, or sinus infections

Ophthalmic Use

Used in eye drops for pupil dilation (mydriasis)

Reduces redness in the eyes caused by minor irritations

Hypotension Management

Used in injectable form to treat hypotension (low blood pressure), especially during anesthesia

Pharmaceutical Ingredient

Used in combination with other medications for cold, flu, and allergy relief formulations

Mechanism of Action

Phenylephrine Hydrochloride stimulates α1-adrenergic receptors on blood vessels, leading to vasoconstriction.

This constriction reduces blood flow to swollen tissues, decreasing inflammation and congestion.

Increases blood pressure by tightening blood vessels without significantly affecting heart rate.

Dosage & Administration

Oral: Typically 10 mg every 4-6 hours for adults (as a nasal decongestant)

Ophthalmic: 2.5% or 10% solution applied as eye drops

Intravenous (IV): Dosage varies depending on the condition being treated

Side Effects & Precautions-Common Side Effects, Increased blood pressure, Dizziness, Insomnia, Headache, Nausea.

Serious Reactions (Rare): Severe hypertension, Reflex bradycardia, Arrhythmia, Blurred vision

Precautions: Should be used with caution in patients with hypertension, heart disease, hyperthyroidism, or diabetes

Storage & Handling: Store in a cool, dry place at room temperature (15-30°C)

Packaging: Usually supplied in airtight, light-resistant containers

Shelf Life: Typically 2-3 years if stored properly

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• Item Code: 61-76-7
• Production Capacity: 5000
• Delivery Time: Immediate
• Packaging Details: drum

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We are offering high quality of Benzyl Benzoate.We are known for manufacturing, exporting, distributing, trading and supplying Benzyl Benzoate in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Benzyl Benzoate in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Benzyl Benzoate Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing  Benzyl Benzoate as well as Intermediates of Benzyl Benzoate.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Benzyl Benzoate to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Chemical Identity:
Chemical Name: Benzyl Benzoate
CAS Number: 120-51-4
Molecular Formula: C14H12O2
Molecular Weight: 212.25 g/mol
Synonyms: Benzenecarboxylate, Benzyl ester of benzoic acid, Benzoic acid benzyl ester
Chemical Structure: Benzyl Benzoate consists of a benzyl group (C6H5CH2) esterified with benzoic acid (C6H5COOH).
Physical and Chemical Properties:
Appearance: Colorless to pale yellow liquid or crystalline powder (at lower temperatures).
Odor: Characteristic sweet, floral odor (often compared to jasmine).
Melting Point: 20–22°C (68–72°F), typically a liquid at room temperature, but can solidify under cooler conditions.
Boiling Point: 323°C (613°F) at 760 mmHg.
Density: 1.10 g/cm³ at 25°C.
Solubility:Soluble in alcohol, acetone, and ether.
Slightly soluble in water.
Readily soluble in organic solvents and oils.
Vapor Pressure: Very low, indicating it is not highly volatile under standard conditions.
Refractive Index: 1.569–1.572.
chemical Reactivity:Reactivity: Benzyl benzoate is stable under normal conditions but can undergo hydrolysis (breakdown into benzyl alcohol and benzoic acid) when exposed to strong acids or bases.
Acidity/Basicity: Slightly acidic due to the ester group (though not strongly so).
Hydrolysis: Can be hydrolyzed into its constituent compounds, benzyl alcohol, and benzoic acid, when exposed to strong acids or bases.
Uses & Applications:
Pharmaceutical Uses:
Anti-parasitic Treatment: Used topically as an anti-parasitic agent, most commonly in the treatment of scabies and lice. It works by acting as a miticide and insecticide.
Topical Medication: Often included in lotions or creams for treating conditions like psoriasis and eczema.
Cosmetic & Personal Care Products:As a fragrance ingredient in lotions, perfumes, and creams due to its characteristic floral scent.Used as a fixative to extend the longevity of other fragrances.
Solvent: Acts as a solvent for various substances in cosmetic formulations.
Industrial Applications:Used as a plasticizer in the production of plastics, including cellulose-based plastics and resins.
Solvent for dyes in certain applications like fabric treatments and paints.
Used in the manufacturing of lubricants and oils.

Precautions:Avoid direct contact with eyes and mucous membranes, as it may cause irritation.
Wear gloves and protective clothing when handling in large quantities.
Inhalation Hazard: Inhalation of high concentrations of vapors should be avoided, as it may cause respiratory irritation.

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• Delivery Time: prompt
• Packaging Details: 25kgs

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We are offering high quality of Imipramine HCL. We are known for manufacturing, exporting, distributing, trading and supplying Imipramine HCL in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Imipramine HCL in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Imipramine HCL. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Imipramine HCL as well as Intermediates of Imipramine HCL.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Imipramine HCL to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Imipramine Hydrochloride (HCL) is a medication primarily used in the treatment of depression and certain other mood disorders. It belongs to the class of drugs known as tricyclic antidepressants (TCAs). Below are the technical details of imipramine HCL:

Chemical Structure

IUPAC Name: 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride

Molecular Formula: C19H24ClN

Molecular Weight: 291.86 g/mol

CAS Number

CAS Registry Number: 113-52-0

Pharmacological Class

Drug Class: Tricyclic antidepressant (TCA)

Dosage and Administration

Oral Dosage Forms:

Tablets: Typically 25 mg, 50 mg, and 75 mg formulations.

Usual Adult Dose for depression: Starting dose is generally 25-50 mg per day, increasing to 150-200 mg daily (divided doses or single dose).

For enuresis in children: Starting dose is usually 25 mg at bedtime.

Pediatric Dose: Dosage for children varies based on weight and condition, typically starting at a lower dose than adults.

Side Effects

Common Side Effects:

Dry mouth, Drowsiness or sedation

Constipation, Blurred vision

Urinary retention, Weight gain, Dizziness

Serious Side Effects:

Arrhythmias (heart irregularities)

Seizures

Hypotension (low blood pressure)

Risk of suicidal thoughts and behavior (especially in younger individuals)

Orthostatic hypotension (drop in blood pressure when standing up)

Contraindications

Absolute Contraindications:

Acute recovery phase from a myocardial infarction (heart attack)

Patients with a history of arrhythmias

Hypersensitivity to imipramine or other tricyclic antidepressants

Relative Contraindications:

Caution in patients with a history of seizures, liver disease, or urinary retention.

Drug Interactions

CYP450 Enzyme Inhibitors: Imipramine is metabolized by the CYP2D6 enzyme, and drugs that inhibit this enzyme (e.g., fluoxetine, paroxetine) can increase imipramine levels.

Monoamine Oxidase Inhibitors (MAOIs): Contraindicated combination due to risk of severe hypertensive crisis.

Alcohol: Alcohol can potentiate the sedative effects of imipramine.

Storage

Store at room temperature (20–25°C or 68–77°F) in a tightly closed container, away from moisture and heat.

 

 

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Dextromethorphan HBr (Hydrobromide) is a commonly used antitussive (cough suppressant) that is available in various formulations, including powder form for pharmaceutical use. Dextromethorphan is widely used in over-the-counter (OTC) cough and cold medications. When it is in its hydrobromide form, it is often utilized in preparations that are meant to be mixed into solutions or other oral dosage forms.

Here’s a detailed description of Dextromethorphan HBr Powder:

1. Chemical Description:

Chemical Name: Dextromethorphan Hydrobromide

Molecular Formula: C18H25NO·HBr

Molecular Weight: 370.31 g/mol

CAS Number: 125-71-3 (Dextromethorphan Hydrobromide)

Synonyms: Dextromethorphan HBr, Dextromethorphan Hydrobromide

Dextromethorphan HBr is a synthetic derivative of morphine but is not addictive or habit-forming at therapeutic doses. It works by affecting the brain's cough center, suppressing the urge to cough without causing sedation or respiratory depression at usual doses.

3. Uses and Indications:

Cough Suppressant: Dextromethorphan is primarily used to suppress coughing associated with common colds, bronchitis, or other respiratory conditions where coughing is present but not productive.

Relief of Dry Cough: It is effective for treating dry, non-productive coughs that do not produce mucus or phlegm.

Over-the-counter medications: Dextromethorphan is included in many OTC cough syrups, lozenges, and tablets.

The powdered form of Dextromethorphan HBr may be used as an intermediate in the manufacture of these finished pharmaceutical products, or it can be used directly for patients requiring precise dosage formulations in clinical settings.

4. Physical Characteristics:

Appearance: Dextromethorphan HBr powder is typically a white to off-white crystalline powder.

Solubility: It is soluble in water and alcohol, which makes it easy to incorporate into liquid or syrup formulations.

Odor: The powder is odorless or may have a faint, characteristic smell.

5. Purity:

Pharmaceutical-grade Dextromethorphan HBr powder typically has a purity of 98% or higher. It is essential for the powder to meet stringent quality control standards to ensure that the correct dose is delivered in the final formulation.

6. Dosage and Strength:

Dextromethorphan HBr powder is often used in the preparation of oral dosage forms, such as syrups, tablets, or capsules. The specific dosage will depend on the final formulation and the intended use. Typical oral dosages for adults are:

10-20 mg every 4-6 hours as needed.

Maximum daily dose typically 120 mg (for adults).

Children's dosages depend on age, and the drug should be administered according to medical guidance to avoid potential overuse, which can lead to serious side effects.

7. Side Effects:

Although Dextromethorphan HBr is generally well tolerated, it may cause side effects, especially if taken in excess or in combination with other substances.

Common side effects include:

Drowsiness or dizziness

Nausea

Vomiting

Stomach discomfort

Severe side effects (more common with abuse or misuse):

Hallucinations (due to higher doses)

Elevated heart rate or high blood pressure

Respiratory distress (with excessive doses)

Severe sedation (especially if combined with alcohol or other central nervous system depressants)

 

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• Port of Dispatch: Mumbai
• Production Capacity: 2000 kilo
• Delivery Time: Immediate
• Packaging Details: 5/10/25 kgs

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We are offering high quality of Loteprednol Etabonate Powder. We are known for manufacturing, exporting, distributing, trading and supplying Loteprednol Etabonate Powder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Loteprednol Etabonate Powder in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Loteprednol Etabonate Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Loteprednol Etabonate Powder as well as Intermediates of Loteprednol Etabonate Powder.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Loteprednol Etabonate Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Levetiracetam: Detailed Description

1. General Information

Drug Name: Levetiracetam

Brand Names: Keppra, Elepsia XR, Spritam, Roweepra

Drug Class: Antiepileptic (Anticonvulsant)

2. Mechanism of Action

Levetiracetam works by binding to the synaptic vesicle protein 2A (SV2A) in the brain. This helps regulate neurotransmitter release and stabilizes neuronal activity, reducing seizure occurrence. Unlike other antiepileptic drugs, it does not act on sodium or calcium channels.

3. Indications (Uses)

Levetiracetam is primarily used for treating epilepsy:

Partial-onset seizures (focal seizures) in adults and children

Myoclonic seizures in juvenile myoclonic epilepsy

Tonic-clonic seizures (generalized seizures) in idiopathic generalized epilepsy

4. Dosage & Administration

Adults & Children (≥12 years):

Initial dose: 500 mg twice daily

Maintenance dose: 1000–3000 mg/day (adjusted as needed)

Pediatrics:

Dosage varies based on weight and age

Renal Impairment:

Dosage adjustment is required

Route of Administration:

Oral (tablets, extended-release tablets, liquid)

Intravenous (IV)

5. Side Effects

Common Side Effects:

Drowsiness, fatigue

Dizziness

Irritability

Weakness

Nasal congestion

Serious Side Effects:

Behavioral changes (aggression, depression, suicidal thoughts)

Hallucinations

Severe allergic reactions (rash, swelling)

Coordination problems

6. Contraindications & Precautions

Contraindications:

Hypersensitivity to levetiracetam

Precautions:

Patients with kidney disease (dose adjustment required)

History of psychiatric disorders (risk of mood changes)

Pregnant women (only use if necessary)

Avoid abrupt discontinuation (may cause seizure rebound)

7. Drug Interactions

Minimal drug interactions compared to other anticonvulsants

Can be used with other antiepileptic drugs but may enhance sedation

Alcohol and sedatives increase drowsiness

8. Pregnancy & Lactation

Pregnancy Category C (risk not ruled out; use only if benefits outweigh risks)

Breastfeeding: Levetiracetam passes into breast milk; caution is advised

 

 

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• Packaging Details: HDPE DRUM PACK

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We are offering high quality of Gramicidin. We are known for manufacturing, exporting,distributing, trading and supplying Gramicidin in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Gramicidin in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier

of Gramicidin Nowadays Shreeji Pharma International is one of the leading manufacturer

and exporter, who is manufacturing Gramicidin as well as Intermediates of Gramicidin.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Gramicidin to countries like Gulf Countries,South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries

Chemical Name: Gramicidin D (a mixture of gramicidins A, B, and C)
Common Name: Gramicidin
CAS Number: 1405-97-6
Molecular Formula: Approx. C99H139N21O17 (varies slightly depending on the component)
Molecular Weight: Approx. 1882.3 g/mol
Appearance: White to off-white, amorphous or crystalline powder
Odor: Odorless or faint characteristic odor
Solubility: Soluble in ethanol, methanol, chloroform, and other organic solvents; poorly soluble in water
Storage Conditions: Store in a tightly sealed container, in a cool, dry place (typically 2–8°C), away from light and moisture

Pharmacological Classification:

Class: Polypeptide antibiotic

Source: Isolated from Bacillus brevis

Use: Topical antibiotic (primarily for skin and eye infections)

Mechanism of Action:Gramicidin disrupts bacterial cell membrane integrity by forming channels or pores in the membrane. This increases membrane permeability to monovalent cations (e.g., Na⁺, K⁺), leading to ionic imbalance and bacterial cell death.

Active mainly against Gram-positive bacteria

Not effective against Gram-negative organisms due to their outer membrane

Applications:

Topical use only (due to systemic toxicity)

Used in combination with other antibiotics (e.g., neomycin, polymyxin B) in:

Eye drops and ointments

Skin creams and ointments

Ear drops

Sometimes used in lozenges for sore throat (limited use)

Properties:

Thermally stable at room temperature

Sensitive to strong acids and bases

Biologically active at low concentrations

Side Effects:Local irritation, redness, or itching (especially with prolonged use)

Allergic reactions (rare)

Toxic if used systemically — not suitable for injection or oral use

Not to be used on large wounds or broken skin to avoid absorption

Precautions & Warnings:

Only for external/topical use

Avoid contact with mucous membranes unless specifically formulated (e.g., eye/ear drops)

Do not use in deep or puncture wounds

Monitor for allergic reaction, especially in sensitive individuals

Not recommended during pregnancy or lactation unless prescribed

 

 

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We are offering high quality of Fully Refined Paraffin Wax. We are known for manufacturing, exporting, distributing, trading and supplying Fully Refined Paraffin Wax in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Fully Refined Paraffin Wax in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Fully Refined Paraffin Wax

Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Fully Refined Paraffin Wax as well as Intermediates of Fully Refined Paraffin Wax.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Fully Refined Paraffin Wax to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Refined paraffin wax is a versatile and widely used material in industries like candle making, cosmetics, pharmaceuticals, and packaging. Here are its technical details:

1. Chemical Composition:

Main Ingredient: Paraffin wax is primarily composed of saturated hydrocarbons, mainly alkanes (C20-C40).

Molecular Formula: CnH2n+2 (where "n" is the number of carbon atoms in the chain).

Purity: Refined paraffin wax is typically purified to remove impurities such as oils, color, and odor.

2. Physical Properties:

Appearance: White, odorless, and tasteless solid. It has a smooth, waxy texture.

Melting Point: Typically between 46°C to 68°C (115°F to 154°F), depending on the specific grade and composition.

Density: 0.8 to 0.9 g/cm³ (depending on the grade).

Viscosity: Low viscosity when melted, making it easy to pour or mold.

Hardness: Soft to medium hardness, varying with the grade and the level of refinement.

3. Thermal Properties:

Heat Resistance: Paraffin wax is stable up to 200°C (392°F). It begins to soften or melt at lower temperatures, typically between 46°C to 68°C (115°F to 154°F).

Heat of Fusion: Varies with purity but generally ranges from 170 to 200 J/g.

4. Solubility:

Solubility in Water: Insoluble in water.

Solubility in Solvents: Soluble in organic solvents like benzene, toluene, and hexane.

5. Mechanical Properties:

Brittleness: At lower temperatures, paraffin wax becomes brittle and may crack.

Elasticity: Low elasticity. It does not exhibit significant stretchability or flexibility.

6. Common Uses:

Candle Making: Paraffin wax is the most commonly used material for candles due to its ease of molding, relatively low cost, and ability to hold fragrance.

Cosmetics & Personal Care: Used in lip balms, lotions, and moisturizers for its emollient properties.

7. Environmental and Safety Aspects:

Non-Toxic: Paraffin wax is considered non-toxic and safe for most applications.

Biodegradability: Not biodegradable, but paraffin wax is considered less harmful to the environment compared to other synthetic materials.

Advantages of Refined Paraffin Wax:

Versatility: It can be used in a wide range of applications, from industrial uses to consumer goods.

 

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• Packaging Details: bag or drum

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We are offering high quality of Trimagnesium Citrate. We are known for manufacturing, exporting, distributing, trading and supplying Trimagnesium Citrate  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Trimagnesium Citrate  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Trimagnesium Citrate. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Trimagnesium Citrate as well as Intermediates of Trimagnesium Citrate.  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Trimagnesium Citrate to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Trimagnesium Citrate is a magnesium supplement that is commonly used to treat or prevent magnesium deficiency. It is a compound formed by combining magnesium with citric acid, resulting in a more easily absorbed form of magnesium that is often utilized for its various health benefits, particularly related to muscle function, bone health, and cardiovascular health.
Here are the key details about Trimagnesium Citrate:
Chemical Structure and Properties
Chemical Name: Trimagnesium citrate
Molecular Formula: C6H6Mg3O12
Appearance: A white, crystalline powder.
Solubility: It is soluble in water, making it easy for the body to absorb when taken orally.
Uses and Benefits
Trimagnesium citrate is used for several purposes, including:
Magnesium Supplementation: It is used to treat or prevent magnesium deficiency, a common issue in people with certain health conditions, such as gastrointestinal diseases, chronic alcoholism, or those on certain medications like diuretics.
Muscle and Nerve Function: Magnesium is vital for the proper functioning of muscles and nerves. Supplementing with magnesium can help prevent muscle cramps, spasms, and weakness associated with magnesium deficiency.
Bone Health: Magnesium works alongside calcium and vitamin D to maintain bone strength. It is essential for bone formation and helps regulate calcium in bones.
Cardiovascular Health: Magnesium supports normal heart rhythm, helps regulate blood pressure, and plays a role in the prevention of heart disease.
Digestive Health: Magnesium has mild laxative properties and is sometimes used to relieve constipation.
Migraine Prevention: Some studies suggest that magnesium supplementation can help reduce the frequency and severity of migraines.
 Side Effects
Magnesium supplements, including Trimagnesium citrate, are generally considered safe when taken as directed. However, taking excessive amounts can lead to side effects:
Common Side Effects:
Diarrhea (especially if used as a laxative)
Stomach upset or cramps
Nausea
Serious Side Effects (associated with excessive magnesium intake):
Low blood pressure
Respiratory depression (difficulty breathing)
Irregular heart rhythms
Severe diarrhea or dehydration
People with kidney disease or impaired kidney function should be cautious about taking magnesium supplements, as their ability to eliminate excess magnesium is reduced, potentially leading to toxicity.

Additional Information:

• Item Code: shreeji
• Delivery Time: prompt
• Packaging Details: drum pack

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We are offering high quality of Sodium Starch Glycolate. We are known for manufacturing, exporting, distributing, trading and supplying Sodium Starch Glycolate  in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Sodium Starch Glycolate  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Sodium Starch Glycolate. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Sodium Starch Glycolate as well as Intermediates of Sodium Starch Glycolate.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

 Shreeji Pharma International currently export Sodium Starch Glycolate to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Chemical Information

Chemical Name: Sodium Carboxymethyl Starch

Common Name: Sodium Starch Glycolate (SSG)

Molecular Formula: Varies (complex polymer)

Molecular Weight: Varies depending on starch source and modification

CAS Number: 9063-38-1

Appearance: White or off-white, free-flowing powder

Solubility: Practically insoluble in water but swells rapidly upon contact

pH (1% solution): 5.5 – 7.5

Description & Uses

Sodium Starch Glycolate (SSG) is a superdisintegrant used primarily in the pharmaceutical industry for tablet and capsule formulations. It enables fast breakdown and dissolution, ensuring better absorption of active ingredients.

 

Applications

1. Pharmaceutical Industry

Tablet & Capsule Formulations: Used as a superdisintegrant to aid in rapid drug release.

Orally Disintegrating Tablets (ODTs): Helps in quick disintegration when in contact with saliva.

Wet & Dry Granulation: Suitable for various drug formulation processes.

Advantage: Enhances bioavailability by ensuring rapid tablet breakdown.

 

2. Food Industry

Thickener & Stabilizer: Used in food products like soups, sauces, and baked goods.

Gluten-Free Baking: Helps improve texture and moisture retention.

Advantage: Improves texture and shelf life in food applications.

 

3. Cosmetics & Personal Care

Face Powders & Foundations: Used as a binder and absorbent.

Skincare Creams & Lotions: Acts as a thickening agent.

Advantage: Provides a smooth, silky feel in formulations.

 Properties & Benefits

 Superdisintegrant: Swells 200–300 times its original volume in water, breaking down tablets quickly.
 Biocompatible & Non-Toxic: Safe for pharmaceutical and food applications.
 Stable & Effective Across pH Ranges: Works well in both acidic and alkaline environments. Versatile: Can be used in direct compression, wet granulation, and capsule formulations.Safety & PrecautionsRegulatory Approval: Approved by USP, EP, BP, and JP for pharmaceutical use.

Concentration Limits: Typically used at 2-8% in tablet formulations.

Storage: Store in a cool, dry place, away from moisture to maintain efficacy

Additional Information:

• Production Capacity: 1 mt
• Delivery Time: prompt
• Packaging Details: 25kgs drum pack

Product Details:

We are offering high quality of Risperidone.We are known for manufacturing, exporting, distributing, trading and supplying Risperidone in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Risperidone in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Risperidone owadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Risperidone as well as Intermediates of Risperidone.Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Risperidone to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Technical specifications::

CAS : 106266-06-2

Purity: >98.0%(T)(HPLC)

Synonyms:::: 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Appearance       White to Almost white powder to crystal

Purity(HPLC)      min. 98.0 area%

Purity(Nonaqueous Titration)    min. 98.0 %

Melting point     170.0 to 174.0 °C

Melting Point     172 °C

Introduction of product::Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone).Schizophrenia and various mood disorders are thought to be caused by an excess of dopaminergic D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways and mesocortical pathways, respectively. Risperidone is thought to reduce this overactivity through inhibition of dopaminergic D2 receptors and serotonergic 5-HT2A receptors in the brain.Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold greater than the drug's binding affinity to D2 receptors, and carries lesser activity at several off-targets which may responsible for some of its undesirable effects.

Risperidone is indicated for the treatment of schizophrenia and irritability associated with autistic disorder. It is also indicated as monotherapy, or adjunctly with lithium or valproic acid, for the treatment of acute mania or mixed episodes associated with bipolar I disorder.Risperidone is additionally indicated in Canada for the short-term symptomatic management of aggression or psychotic symptoms in patients with severe dementia of the Alzheimer type unresponsive to nonpharmacological approaches. 

USES:Risperidone is a second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression.Risperidone is used to treat certain mental/mood disorders. 

Side effect:Drowsiness, dizziness, lightheadedness, drooling, nausea, weight gain, or tiredness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Dizziness and lightheadedness can increase the risk of falling

 

Additional Information:

• Production Capacity: 100 kg
• Delivery Time: prompt
• Packaging Details: HDPE Drum

Product Details:

We are offering high quality of SodiumBicarbonate.We are known for manufacturing, exporting, distributing, trading and supplying Sodium Bicarbonate in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Sodium Bicarbonate  in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Sodium Bicarbonate owadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Sodium Bicarbonate as well as Intermediates of Sodium Bicarbonate.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Sodium Bicarbonate to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Formula weight : 84.0 amu

Melting point    Decomposes at 543 K (270 °C)

Density                2.2 ×103 kg/m3

Solubility            10.3 g in 100g water

Thermochemistry

ΔfH0solid            -951 kJ/mol

S0solid 102 J/mol·K

Introduction of product:

Sodium bicarbonate is baking soda, bicarb or bicarbonate of soda. It is a chemical compound, sodium hydrogen carbonate, with the formula NaHCO₃. The elements within it are sodium, hydrogen, carbon, oxygen. It is a white crystalline powder.

Sodium bicarbonate is an antacid. It is sometimes used to relieve acid indigestion, a sickness caused by lots of acid in one's stomach. This was usually done by mixing sodium bicarbonate with water and drinking it. When there is too much acid, it causes heartburn, an uncomfortable feeling in the stomach. It reacts with acids to produce carbon dioxide gas. It also reacts with bases to reduce their harmful effects.When sodium bicarbonate is heated, it releases carbondioxide and water vapor (gas) and turns into sodium carbonate.Baking soda is rarely found in the earth. It can be manufactured artificially,Sodium bicarbonate (NaHCO₃), or sodium hydrogen carbonate, also known as baking soda, is a soluble white anhydrous or crystalline compound, with a slight alkaline taste resembling that of sodium carbonate. It is found in many mineral springs and also produced artificially.

It is also used as an antacid to treat acid indigestion[?] and heartburn. The anhydrous form is also used to absorb moisture and odours—a box can be left in the refrigerator for this purpose.Sodium bicarbonate, when exposed to a moderately strong acid, releases carbon dioxide:

NaHCO₃ + HCl → NaCl + H₂O + CO₂ (gas)

NaHCO₃ + CH₃COOH → CH₃COONa[?] + H₂O + CO₂ (gas)

It is used in combination with acidic compounds as a leavening agent in baking:

Product Details:

We are offering high quality of DAPOXETINE HCL POWDER  . We are known for manufacturing, exporting, distributing, trading and supplying DAPOXETINE HCL POWDER    in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier DAPOXETINE HCL POWDER    in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of DAPOXETINE HCL POWDER  . Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing DAPOXETINE HCL POWDER   as well as Intermediates of DAPOXETINE HCL POWDER  .  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export DAPOXETINE HCL POWDER   to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

 

Dapoxetine Hydrochloride (HCl) Powder is the active pharmaceutical ingredient (API) used in the formulation of Dapoxetine, a medication primarily prescribed for the treatment of premature ejaculation (PE) in men. It is a selective serotonin reuptake inhibitor (SSRI) and is designed to increase the time it takes to ejaculate and improve control over ejaculation.

1. Chemical Description:

• Chemical Name: (S)-N-(3-(dimethylamino)-1-(2-methoxyphenyl)propyl)-N-methylpropan-2-amine hydrochloride
• Molecular Formula: C19H24N2O·HCl
• Molecular Weight: 316.87 g/mol
• CAS Number: 119356-77-3

Dapoxetine is a potent, short-acting selective serotonin reuptake inhibitor (SSRI). As an SSRI, it works by increasing the serotonin levels in the brain, which can help improve the control of ejaculation in men experiencing PE.

2. Mechanism of Action:

• Selective Serotonin Reuptake Inhibition: Dapoxetine inhibits the reuptake of serotonin (5-HT) at the synaptic cleft. Increased serotonin activity in the brain is thought to help delay ejaculation by enhancing the central nervous system's control over ejaculation.
• Short-Acting Effect: Dapoxetine has a relatively short half-life, which allows for it to be taken on-demand, before sexual activity, rather than as a daily medication like other SSRIs.

3. Uses:

Dapoxetine HCl powder is primarily used in the formulation of medications intended for:

• Premature Ejaculation (PE): Dapoxetine is approved for the treatment of premature ejaculation in men aged 18 to 64. It helps to increase the time before ejaculation and improves control over ejaculation.

Note: Dapoxetine is often prescribed as a short-term treatment for PE and is not intended for long-term use.

4. Physical Characteristics:

• Appearance: Dapoxetine Hydrochloride (HCl) powder is typically a white to off-white crystalline powder.
• Solubility: It is soluble in water and ethanol,

 

Product Details:

We are offering high quality of Copper Gluconate Powder We are known for manufacturing,exporting, distributing, trading and supplying Copper Gluconate Powder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Copper Gluconate Powder in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Copper Gluconate Powder Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Copper Gluconate Powder as well as Intermediates of Copper Gluconate Powder Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Copper Gluconate Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries.
Copper Gluconate Powder is a form of copper supplement that combines the essential trace mineral copper with gluconic acid, a derivative of glucose. It is a white to light tan powder, soluble in water, and is commonly used as a dietary supplement to provide the body with copper, an essential mineral involved in numerous physiological processes.
Chemical Composition:
Formula: Copper Gluconate (Cu(C6H11O7)2)
Copper gluconate consists of copper (Cu) bound to gluconic acid molecules.
The powder contains a specific ratio of copper and gluconic acid that allows for better absorption by the human body compared to other copper salts.
Physical Characteristics:
Appearance: Off-white or light tan powder.
Solubility: Soluble in water, allowing easy incorporation into liquid-based supplements.
Taste: Slightly metallic due to the presence of copper.
Density: Typically light, and it can be easily measured in small amounts.
Source:Copper gluconate is made by reacting copper salts with gluconic acid, which is naturally derived from glucose.
Common Uses of Copper Gluconate Powder:
Cosmetic & Pharmaceutical Use:
Used in topical formulations for its antioxidant properties and potential to help in wound healing or skin health.
Health Benefits of Copper Gluconate:
Antioxidant Properties:
Copper helps in the neutralization of free radicals through enzymes like superoxide dismutase (SOD), offering protective effects against oxidative stress.
Cardiovascular Health:
Copper is involved in the production of red blood cells and hemoglobin, and helps maintain the health of blood vessels and tissues.
Dosage and Recommended Use:
Standard Dosage: The recommended daily intake of copper for adults is approximately 900 micrograms. However, specific dosages may vary depending on individual needs, health conditions, and medical advice.
Copper gluconate powder can be consumed in the form of capsules, tablets, or mixed into liquid solutions, making it flexible in terms of delivery.
Precautions:
Monitor Dosage: Copper supplements should be taken under the supervision of a healthcare provider to ensure the proper dosage and avoid toxicity.
Avoid Overuse: Long-term overuse of copper supplements without medical oversight can result in copper buildup, which is harmful to liver and kidney health.
Storage:
Store copper gluconate powder in a cool, dry place, away from direct sunlight and humidity to maintain its potency.

Additional Information:

• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: india
• Production Capacity: 1 mt
• Delivery Time: prompt
• Packaging Details: Packed in 25 Kgs HDPE Drums

Product Details:

 

 

We are offering high quality of Benzydamine Hcl.We are known for manufacturing, exporting, distributing, trading and supplying Benzydamine Hcl in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Benzydamine Hcl in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Benzydamine Hcl Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing  Benzydamine Hcl as well as Intermediates of Benzydamine Hcl.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Benzydamine Hcl to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Benzydamine Hydrochloride (HCl) is a nonsteroidal anti-inflammatory drug (NSAID) commonly used for its analgesic, anti-inflammatory, and antipyretic properties. It is primarily used as a topical and oral medication to relieve pain and inflammation associated with conditions such as sore throat, dental pain, and inflammation in the mouth and throat.
Here are the detailed description and technical data for Benzydamine Hydrochloride (HCl):
Chemical Identity
Chemical Name: Benzydamine Hydrochloride
CAS Number: 580-07-0 (Benzydamine) / 4421-02-1 (Benzydamine Hydrochloride)
Molecular Formula: C19H22ClNO
Molecular Weight: 303.83 g/mol
Synonyms:1-(Dimethylamino)-3-(benzyloxy)-5-indolemethanamine hydrochloride
Tramen, Diflam, Tantum
Physical and Chemical Properties
Appearance: White to almost white crystalline powder.
Odor: Odorless or nearly odorless.
Taste: Slightly bitter.
Melting Point: 128–132°C (as free base)
Solubility:
Water: Soluble in water (especially in acidic conditions).
Alcohol: Soluble in ethanol.
Chloroform and Acetone: Slightly soluble.
pH: The pH of aqueous solutions of Benzydamine Hydrochloride is typically around 4–6 (slightly acidic).
Boiling Point: Decomposes before reaching its boiling point.
Uses and Applications:Benzydamine HCl is used for its anti-inflammatory and analgesic properties in both oral and topical treatments:
Oral and Topical Applications:Benzydamine is commonly used in oral solutions and mouthwashes for the relief of pain and inflammation associated with conditions like sore throats, pharyngitis, and gingivitis. It is also used as a topical spray for painful conditions in the mouth or throat.
Dental Care: It is used in certain oral care products like mouth rinses and lozenges to provide relief from painful dental conditions, including dental surgery recovery, oral ulcers, and gum inflammation.
Post-Surgical Inflammation: It can be used to alleviate inflammation and pain following dental or throat surgeries.
Anti-inflammatory: It can be used to relieve pain and swelling in the musculoskeletal system (e.g., muscle pain, arthritis) when applied topically.

 

 

Additional Information:

• Port of Dispatch: INDIA
• Production Capacity: 20 MT
• Delivery Time: PROMPT
• Packaging Details: DRUM

Product Details:

We are offering high quality of Potassium Iodide. We are known for manufacturing, exporting, distributing, trading and supplying Potassium Iodide in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Potassium Iodide in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Potassium Iodide. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Potassium Iodide as well as Intermediates of Potassium Iodide.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Potassium Iodide to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

1. Chemical Identity

Chemical Name: Potassium Iodide

Chemical Formula: KI

Molecular Weight: 166.00 g/mol

CAS Number: 7681-11-0

EC Number: 231-659-4

Appearance: White crystalline powder

Odor: Odorless

Solubility: Highly soluble in water, ethanol, and glycerol

Melting Point: 681°C (1257.8°F)

Boiling Point: Decomposes before boiling

2. Properties

Ionic Compound: Consists of potassium (K⁺) and iodide (I⁻) ions

Stability: Stable under normal conditions but sensitive to light and air (may turn yellow due to oxidation)

pH: Slightly alkaline in aqueous solution

3. Uses and Applications

Pharmaceutical Use:

Used as an antithyroid agent for hyperthyroidism treatment

Administered in potassium iodide tablets for thyroid protection against radioactive iodine

Component of Lugol’s iodine solution, which is used as an antiseptic and in medical imaging

Radiation Protection:

Used to block the uptake of radioactive iodine by the thyroid gland during nuclear accidents

Nutritional Supplement:

Added to iodized salt to prevent iodine deficiency disorders (IDD)

Industrial Applications:

Used in chemical synthesis and as a reagent in laboratories

Serves as an additive in photographic film processing

Employed in food preservation and animal feed supplements

Cosmetic Industry:

Included in skincare formulations to support wound healing

4. Safety and Handling

Storage:

Store in a cool, dry place, away from direct light and moisture

Keep in tightly sealed containers to prevent oxidation

Handling Precautions:

Use gloves and safety goggles when handling the powder

Avoid inhalation and direct contact with skin and eyes

Toxicity:

Generally safe in prescribed doses but excessive intake can cause iodism (symptoms include metallic taste, throat swelling, nausea, and skin eruptions)

Contraindicated in individuals with iodine hypersensitivity or kidney disorders

5. Regulatory Information

FDA & WHO Approved: Used in pharmaceuticals and food fortification

UN Number: Not classified as a hazardous substance

 

HS Code: 28276000 (for international trade classification)

Additional Information:

• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: India
• Production Capacity: 20MT
• Delivery Time: Prompt
• Packaging Details: Packed in 25 Kgs HDPE Drums

Product Details:

We are offering high quality of Pioglitazone api. We are known for manufacturing, exporting, distributing, trading and supplying Pioglitazone api in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Pioglitazone api in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Pioglitazone api. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Pioglitazone api as well as Intermediates of Pioglitazone api.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Pioglitazone api to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

1. General Information

Chemical Name: Pioglitazone Hydrochloride

Common Name: Pioglitazone

Molecular Formula: C19H20N2O3S•HCl

Molecular Weight: 392.90 g/mol (Hydrochloride salt)

CAS Number: 111025-46-8 (Pioglitazone base), 112529-15-4 (Pioglitazone HCl)

Drug Class: Thiazolidinedione (TZD) / Antidiabetic Agent

2. Physical & Chemical Properties

Appearance: White to off-white crystalline powder

Odor: Odorless

Solubility:

Freely soluble in dimethyl sulfoxide (DMSO)

Sparingly soluble in methanol

Practically insoluble in water

Melting Point: Approximately 193-194°C

pH (in aqueous solution): Slightly acidic

Stability: Stable under normal storage conditions; sensitive to moisture and light

3. Mechanism of Action

Pioglitazone is a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist, which enhances insulin sensitivity in adipose tissue, skeletal muscle, and the liver. It reduces insulin resistance and lowers blood glucose levels by improving glucose uptake and decreasing hepatic glucose production.

4. Applications & Uses

Used in the formulation of oral antidiabetic medications.

Primarily prescribed for type 2 diabetes mellitus (as monotherapy or in combination with metformin, sulfonylureas, or insulin).

Investigated for potential benefits in non-alcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS).

5. Regulatory & Compliance

Approved by US FDA, EMA, CDSCO, TGA, and other health authorities.

Manufactured under Good Manufacturing Practices (GMP).

Requires stability studies as per ICH guidelines.

6. Storage & Handling

Storage Conditions: Store at 25°C (77°F) with excursions permitted to 15°C–30°C (59°F–86°F).

Precautions:

Protect from light and moisture.

Store in a tightly sealed container.

Avoid exposure to heat and strong oxidizing agents.

7. Packaging & Availability

Typically available in 25kg / 50kg fiber drums with inner double polyethylene bags.

Custom packaging options available as per customer requirements.

Additional Information:

• Item Code: 112529-15-4.
• Delivery Time: Prompt
• Packaging Details: Packed in 25 Kgs HDPE Drums

Product Details:

We are offering high quality of Mecetronium Ethyl sulphate We are known for manufacturing, exporting, distributing, trading and supplying Mecetronium Ethyl sulphate in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Mecetronium Ethyl sulphate in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Mecetronium Ethyl sulphate .Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Mecetronium Ethyl sulphate as well as Intermediates of Mecetronium Ethyl sulphate .Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Mecetronium Ethyl sulphatet  countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries

Mecetronium ethyl sulfate, also known by its chemical name ethyl 3-(2-methyl-2-propylthiazol-4-yl)-1-ethyl-1H-imidazole-4-sulfonate, is a synthetic quaternary ammonium compound. It’s primarily used in pharmaceuticals and medical products, especially in the treatment of skin conditions and as an antiseptic agent.

Chemical Structure:Mecetronium ethyl sulfate belongs to the class of quaternary ammonium salts. It consists of a quaternary nitrogen atom (a nitrogen atom attached to four substituent groups) that is bonded to an ethyl group and a sulfonate group (ethyl sulfate).

The structure also contains a thiazole ring (a sulfur and nitrogen-containing heterocyclic compound), contributing to its antimicrobial properties.

The imidazole ring, also present in the structure, is a common feature in bioactive compounds, further enhancing the compound’s pharmacological activity.

Uses:Antiseptic: Mecetronium ethyl sulfate is used in topical formulations, particularly for treating skin infections or wounds. It can help disinfect and prevent microbial growth in minor cuts, abrasions, and burns.

Cosmetic formulations: It is sometimes found in cosmetic products like skin creams, lotions, and cleansers due to its ability to cleanse and purify the skin.

In the pharmaceutical industry: Mecetronium ethyl sulfate is sometimes used in oral care products or mouthwashes for its antimicrobial effects.

Mode of Action:It works by disrupting the microbial cell membrane, leading to the death of bacteria and other pathogens. This property makes it effective as a bactericidal agent.

Mecetronium ethyl sulfate can also serve as an antifungal agent, particularly against yeasts and certain molds.

Safety and Side Effects:

As with many antiseptic agents, excessive use or overexposure to mecetronium ethyl sulfate can cause skin irritation or allergic reactions.

It is generally considered safe when used in regulated amounts, particularly in topical applications.

Formulations and Availability:

Available in various topical solutions, creams, or ointments, as well as in oral formulations (such as mouthwashes).

It’s used primarily in pharmaceutical and cosmetic products that target skin hygiene or wound care.

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• Item Code: 3006-10-8
• Delivery Time: Prompt
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We are offering high quality of Vildagliptin . We are known for manufacturing, exporting, distributing, trading and supplying Vildagliptin   in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Vildagliptin   in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
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Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Vildagliptin  to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
 
Vildagliptin is an oral medication used to manage type 2 diabetes mellitus. It belongs to a class of drugs called DPP-4 (dipeptidyl peptidase-4) inhibitors, which help regulate blood sugar levels by enhancing the body’s own ability to control blood sugar.
General Information:
Chemical Name: (S)-1-(3-Hydroxy-1-adamantyl)-3-(trifluoromethyl)urea.
Molecular Formula: C17H22F3N3O2.
CAS Number: 274901-16-5.
Brand Names: Galvus (most commonly used brand name).
Drug Class: DPP-4 inhibitor.
Mechanism of Action:
Vildagliptin works by inhibiting the DPP-4 enzyme, which is involved in the breakdown of incretin hormones like glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These incretin hormones are important for regulating blood sugar levels, as they:
Stimulate insulin release from the pancreas in response to meals.
Inhibit glucagon secretion, which reduces the liver's production of glucose.
By inhibiting DPP-4, vildagliptin increases the levels of these active incretin hormones, leading to improved insulin secretion, reduced glucagon levels, and better control of blood sugar levels.
Common Side Effects:
Headache.
Nausea.
Dizziness.
Upper respiratory tract infections (e.g., cold, sore throat).
Fatigue.
Back pain.
Serious Side Effects (Less Common but Serious):
Hypoglycemia (low blood sugar): When used in combination with other diabetes medications like sulfonylureas or insulin, the risk of low blood sugar may increase.
Pancreatitis (inflammation of the pancreas): Though rare, vildagliptin has been associated with cases of pancreatitis. Symptoms include severe abdominal pain, nausea, and vomiting.
Hepatotoxicity (liver damage): In some cases, vildagliptin may affect liver function, so liver enzymes should be monitored regularly.
Angioedema (swelling of deeper layers of the skin, especially around the face and throat): This rare but serious allergic reaction can be life-threatening and requires immediate medical attention.
Severe allergic reactions: Rash, itching, or swelling can occur in rare cases.
Precautions:
Renal (Kidney) Impairment:
As vildagliptin is excreted by the kidneys, caution is required when using it in patients with renal impairment. The dosage may need to be adjusted in patients with moderate to severe kidney problems.

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• Item Code: 30049099
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We are offering high quality of Hydroxychloroquine Sulfate powder. We are known for manufacturing, exporting, distributing, trading and supplying Hydroxychloroquine Sulfate powder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Hydroxychloroquine Sulfate powder in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

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Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Hydroxychloroquine Sulfate powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Hydroxychloroquine Sulfate is the sulfate salt of Hydroxychloroquine, a medication used primarily to treat malaria, lupus, and rheumatoid arthritis. It is an antimalarial agent and has immunomodulatory properties.

Here is a general overview of the technical data for Hydroxychloroquine Sulfate:

1. Chemical Information:

IUPAC Name: 2-[(7-Chloro-4-quinolinyl)(ethyl)amino]ethanol sulfate

Molecular Formula: C18H26ClN3O•H2SO4

Molecular Weight: 399.9 g/mol

CAS Number: 747-36-4 (Hydroxychloroquine)

Chemical Structure: Hydroxychloroquine Sulfate is a combination of Hydroxychloroquine (C18H26ClN3O) and sulfuric acid (H2SO4).

2. Physical Properties:

Appearance: Hydroxychloroquine Sulfate is typically a white to off-white crystalline powder.

Solubility: It is soluble in water and slightly soluble in alcohol and acetone.

Melting Point: Approximately 360–370°C (as Hydroxychloroquine sulfate).

Uses:

Malaria Treatment and Prevention:

Hydroxychloroquine is used to treat acute attacks of malaria caused by Plasmodium species. It can also be used to prevent malaria in areas where the disease is prevalent.

Autoimmune Diseases:

Rheumatoid Arthritis (RA): It is used to reduce inflammation and manage symptoms in people with RA.

Systemic Lupus Erythematosus (SLE or Lupus): Hydroxychloroquine helps manage symptoms like fatigue, rashes, and joint pain in people with lupus.

Other conditions: Occasionally used in the treatment of other autoimmune diseases like dermatomyositis.

Off-Label Uses:

Sometimes used in the management of sarcoidosis, psoriasis, and other inflammatory conditions.

Side Effects:

Most side effects are mild, but serious side effects can include:

Eye Problems: Long-term use can cause retinal damage, so eye exams are typically recommended periodically.

Gastrointestinal Issues: Nausea, diarrhea, and stomach cramps.

Skin Reactions: Rash or pigment changes in the skin.

Heart Issues: Can affect the electrical conduction in the heart, leading to arrhythmias in rare cases.

 

Muscle Weakness: Prolonged use can sometimes cause muscle weakness or neuropathy.

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• Packaging Details: 25 KG DRUM PACKING

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We are offering high quality of Loperamide HCl Powder . We are known for manufacturing, exporting, distributing, trading and supplying Loperamide HCl Powder   in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Loperamide HCl Powder   in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Loperamide HCl Powder . Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Loperamide HCl Powder  as well as Intermediates of Loperamide HCl Powder .   Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Loperamide HCl Powder  to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Loperamide HCl Powder – Detailed Description

Overview:

Loperamide Hydrochloride (HCl) is a synthetic opioid-derived antidiarrheal agent used primarily to manage acute and chronic diarrhea. It works by slowing intestinal motility and reducing fluid secretion, making it effective in treating conditions such as irritable bowel syndrome (IBS) and traveler's diarrhea.

Chemical Information:

Chemical Name: Loperamide Hydrochloride

IUPAC Name: 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide hydrochloride

Molecular Formula: C29H33ClN2O2·HCl

Molecular Weight: 513.5 g/mol

CAS Number: 34552-83-5

Appearance: White to off-white crystalline powder

Solubility: Slightly soluble in water, freely soluble in methanol and ethanol

Mechanism of Action:

Loperamide acts on opioid receptors in the intestinal wall, inhibiting peristalsis and prolonging transit time. It also enhances water and electrolyte absorption while reducing fluid secretion, leading to firmer stools and relief from diarrhea.

Pharmacokinetics:

Absorption: Poorly absorbed from the gastrointestinal (GI) tract

Onset of Action: 1–3 hours

Half-Life: ~9–14 hours

Metabolism: Primarily metabolized in the liver by CYP3A4

Excretion: Mainly through feces, with minimal renal elimination

Uses & Applications:

Treatment of acute and chronic diarrhea

Symptomatic relief in conditions like IBS-D (diarrhea-predominant irritable bowel syndrome)

Management of traveler's diarrhea

Reduction of stool output in patients with ileostomies

Dosage (For Reference Only, Consult a Doctor):

Adults: 4 mg initially, followed by 2 mg after each loose stool (Max: 16 mg/day)

Children (≥6 years): Lower doses based on body weight

Not recommended for children under 6 years

Side Effects:

Constipation

Abdominal pain

Dry mouth

Drowsiness or dizziness

Nausea

Precautions & Warnings:

Not for infectious diarrhea (e.g., bacterial, viral infections)

Avoid use in patients with bloody diarrhea or high fever

Overuse or overdose can cause serious cardiac effects (QT prolongation, Torsades de Pointes)

Should not be used in cases of C. difficile-associated diarrhea

 

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We are offering high quality of Tofacitinib. We are known for manufacturing, exporting, distributing, trading and supplying Tofacitinib  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Tofacitinib  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Tofacitinib. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Tofacitinib as well as Intermediates of Tofacitinib.  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Tofacitinib to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
 Tofacitinib is an oral Janus kinase (JAK) inhibitor used to treat various inflammatory conditions, including rheumatoid arthritis (RA), psoriatic arthritis (PsA), ulcerative colitis (UC), and atopic dermatitis (AD). It works by inhibiting the activity of one or more of the Janus kinase family of enzymes, which play a key role in the immune system and inflammation.
Description & Properties:
Chemical Formula: C16H20N6O
Molecular Weight: 312.37 g/mol
Appearance: White to off-white crystalline powder.
Solubility: Soluble in water and organic solvents like ethanol.
Melting Point: 161°C to 164°C.
Tofacitinib is typically available in oral tablet form, and it is often prescribed for patients who do not respond well to other disease-modifying antirheumatic drugs (DMARDs) or biologics.
Mechanism of Action:
Tofacitinib works by inhibiting Janus kinase enzymes (JAK1, JAK3, and, to a lesser extent, JAK2). These enzymes play a critical role in the signaling pathways of various cytokines involved in the inflammatory response. By inhibiting JAKs, Tofacitinib reduces the activity of immune cells that contribute to inflammation, thereby helping to control symptoms and slow the progression of inflammatory diseases.
Uses:Tofacitinib is used for the treatment of several chronic inflammatory conditions:
Dosage and Administration:
Rheumatoid Arthritis (RA): The usual starting dose is 5 mg twice daily. In certain cases, the dose may be reduced to 5 mg once daily or adjusted based on efficacy and tolerability.
Psoriatic Arthritis (PsA): Similar to RA, the starting dose is typically 5 mg twice daily. Dose adjustments may be made depending on response and side effects.
Ulcerative Colitis (UC): Initially, a higher dose is used. The typical dosing is 10 mg twice daily for the first 8 weeks, followed by 5 mg twice daily after the initial phase.
Atopic Dermatitis (AD): The dose is typically 5 mg twice daily.
Tofacitinib should be taken with or without food. The dosage might be adjusted based on individual responses and any side effects observed, and it should be prescribed by a healthcare professional who monitors the patient closely.
Tofacitinib can cause a range of side effects, some of which may be serious. Common and serious side effects include:
Storage conditions: Store at room temperature (20–25°C or 68–77°F), away from heat and moisture.
Shelf life: Keep Tofacitinib tablets in their original packaging and tightly closed to prevent moisture and contamination.

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• Item Code: 477600-75-2
• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
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• Production Capacity: 1 MT
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Product Details:

We are offering high quality of Ibandronate Sodium. We are known for manufacturing, exporting, distributing, trading and supplying Ibandronate Sodium in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Ibandronate Sodium in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

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Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Ibandronate Sodium to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Ibandronate Sodium is a medication that belongs to a class of drugs known as bisphosphonates. It is commonly used to treat and prevent osteoporosis and to manage bone complications associated with certain cancers.

Here are the technical details of Ibandronate Sodium:

Chemical Name and Structure

IUPAC Name: 3-(N-hydroxyphosphoryl)-2-methyl-1-hydroxypropylidene)-bisphosphonic acid

Molecular Formula: C9H22NNaO7P2

Molecular Weight: 329.2 g/mol

CAS Number: 114090-90-3

Dosage Forms:

Ibandronate sodium is available in two primary forms:

Oral Tablets – Taken once monthly or as prescribed.

Intravenous (IV) Injection – Administered by a healthcare provider, typically every 3 months.

Dosage:

Oral: The typical dosage is 150 mg once a month, taken on an empty stomach with water, at least 60 minutes before food or other medications.

Intravenous: The IV form is usually administered as a 3 mg dose every 3 months.

Common Side Effects:

Gastrointestinal symptoms like nausea, abdominal pain, heartburn, or indigestion.

Bone, joint, or muscle pain.

Risk of jawbone problems (osteonecrosis) in some cases, especially after dental procedures.

Possible esophageal irritation or ulcers.

Low blood calcium levels (hypocalcemia).

Precautions:

Esophageal Disorders: Ibandronate should not be used in patients with esophageal issues, as it may cause irritation or ulcers.

Renal Function: Caution should be taken in patients with impaired kidney function, and dosage adjustments may be required.

Pregnancy & Lactation: It is not recommended for use during pregnancy or breastfeeding, as its effects on a fetus or infant are not fully known.

Contraindications:

Severe renal impairment (creatinine clearance <30 mL/min).

Hypocalcemia (low calcium levels in the blood).

History of esophageal strictures or other esophageal problems.

Brand Names:

Ibandronate sodium is available under various brand names, including Boniva.

Patient Counseling:

Patients should be advised to stay upright for at least 60 minutes after taking the oral form to avoid esophageal irritation.

Adequate calcium and vitamin D intake should be ensured to support bone health.

If a dose is missed, patients should take it the next morning on an empty stomach but should not take two doses in one day.

 

 

 

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• Delivery Time: PROMPT
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We are offering high quality of Sulfamethaxazole Api Powder. We are known for manufacturing, exporting, distributing, trading and supplying Sulfamethaxazole Api Powder  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Sulfamethaxazole Api Powder  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Sulfamethaxazole Api Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Sulfamethaxazole Api Powder as well as Intermediates of Sulfamethaxazole Api Powder.  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Sulfamethaxazole Api Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
 Sulfamethoxazole is a sulfonamide antibiotic commonly used in combination with trimethoprim to treat a variety of bacterial infections. Below are detailed specifications and information about sulfamethoxazole:
Chemical Name:N-[5-Methyl-3-isoxazolyl] sulfonamide
Molecular Formula:C10H11N3O3S
Molecular Weight:253.28 g/mol
CAS Number:723-46-6
Description:Sulfamethoxazole is a synthetic sulfonamide (a type of antibiotic) that is structurally similar to para-aminobenzoic acid (PABA). It works by inhibiting the synthesis of dihydrofolic acid, an essential precursor in the production of bacterial nucleic acids, effectively stopping bacterial growth.
Physical Appearance:
Form: White to off-white crystalline powder or solid
Odor: Odorless or faint characteristic odor
Taste: Slightly bitter
Solubility:
Water: Slightly soluble in water (0.15 g/100 mL at 25°C)
Ethanol: Soluble in ethanol
Other Solvents: Slightly soluble in acetone
Melting Point:
166–168°C (331°F to 334°F)
Chemical Properties:
pH: The pH of an aqueous solution of sulfamethoxazole is around 5–7.
Stability: Stable under normal conditions, but the compound can degrade when exposed to excessive light, moisture, or extreme temperatures.
Pharmacology:
Mechanism of Action: Sulfamethoxazole works by inhibiting the enzyme dihydropteroate synthase, which is responsible for the synthesis of folic acid in bacteria. This prevents the production of DNA and RNA, which is crucial for bacterial growth and reproduction.
Spectrum of Activity: It is effective against a broad range of Gram-positive and Gram-negative bacteria, including Escherichia coli, Streptococcus pneumoniae, Haemophilus influenzae, and Shigella species.
Uses:
Infections Treated:
Urinary tract infections (UTIs)
Respiratory tract infections
Ear infections
Gastrointestinal infections
Meningitis
Some forms of malaria (when used in combination with other drugs)
Side Effects:Common side effects include nausea, vomiting, loss of appetite, and rash.
Serious side effects include blood disorders (e.g., anemia, leukopenia), liver problems, and severe skin reactions (Stevens-Johnson syndrome).
Hypersensitivity Reactions: Can cause allergic reactions, including rash, fever, or difficulty breathing.
Renal and Hepatic Toxicity: Careful monitoring is required in patients with kidney or liver problems.

 

Additional Information:

• Item Code: 723-46-6
• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer),D/P
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• Production Capacity: 1 MT
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We are offering high quality of Phenylbutazone. We are known for manufacturing, exporting, distributing, trading and supplying Phenylbutazone in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Phenylbutazone in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Phenylbutazone. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Phenylbutazone as well as Intermediates of Phenylbutazone.   Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently exports Phenylbutazone to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

1. General Information: Generic Name: Phenylbutazone, Common Brand Names: Butazolidin, Equipalazone (for veterinary use), Drug Class: Non-Steroidal Anti-Inflammatory Drug (NSAID), Molecular Formula: C₁₉H₂₀N₂O₂, Molecular Weight: 308.38 g/mol

2. Mechanism of Action: Phenylbutazone is a non-selective cyclooxygenase (COX) inhibitor, meaning it blocks both COX-1 and COX-2 enzymes responsible for prostaglandin synthesis. Prostaglandins are lipid compounds involved in inflammation, pain, and fever.

3. Uses and Indications: Human Use (Historically)

Originally used to treat rheumatoid arthritis, ankylosing spondylitis, and gout.

However, due to severe side effects, it is rarely used in humans today.

Horses: Treatment of musculoskeletal disorders (laminitis, arthritis, bursitis, tendonitis).

Dogs: Occasionally prescribed for severe arthritis and musculoskeletal pain.

Cattle: Restricted use in some regions due to drug residue concerns in milk and meat.

4. Pharmacokinetics: Absorption: Rapid oral absorption; peak plasma levels in 2–6 Hours. Distribution: Highly protein-bound (~98%); wide tissue distribution. Metabolism: Metabolized in the liver to oxyphenbutazone (active metabolite)., 5. Dosage and Administration: Horses: Typically 2.2–4.4 mg/kg orally or intravenously every 12–24 hours. Dogs: Less commonly used; dosages vary. Humans: Formerly 100–200 mg/day, but rarely prescribed today due to safety concerns.

6. Side Effects and Risks: Mild Side Effects: Nausea, vomiting, Ulcers and gastrointestinal irritation, Loss of appetite. Severe Side Effects: Bone marrow suppression (agranulocytosis, aplastic anemia), Gastrointestinal bleeding and ulcers, Kidney and liver toxicity.

7. Contraindications: Not recommended for human use due to severe hematological side effects., Avoid in pregnant or lactating animals..

8. Regulatory Status: Human Use: Banned or severely restricted in many countries due to safety concerns, Veterinary Use: Approved in many countries for horses but banned in food animals.

Conclusion: Phenylbutazone was a widely used NSAID but is now largely restricted due to severe side effects. While it remains an important medication in equine medicine, its human use is limited due to serious risks such as bone marrow suppression and gastrointestinal toxicity. 

Additional Information:

• Item Code: 84033
• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: India
• Production Capacity: 20MT
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Product Details:

We are offering high quality of Amisulpride. We are known for manufacturing, exporting, distributing, trading and supplying Amisulpride in Gujarat India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Amisulpride in Gujarat India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

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Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the

Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Amisulpride to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Amisulpride is an atypical antipsychotic medication primarily used to treat schizophrenia and, in some cases, major depressive disorder. It works by selectively blocking dopamine D2 and D3 receptors, helping to balance dopamine levels in the brain.

Chemical Information

Chemical Name: 4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-o-anisamide

Molecular Formula: C17H27N3O4S

Molecular Weight: 369.48 g/mol

CAS Number: 71675-85-9

Physical Properties

Appearance: White or off-white crystalline powder

Solubility: Slightly soluble in water, soluble in ethanol and methanol

Melting Point: ~126-130°C

Purity: Typically ≥ 99% (depending on manufacturer specifications)

Pharmacological Action

Mechanism of Action:

Antagonist at dopamine D2 and D3 receptors

Low affinity for serotonin (5-HT) receptors

Effects depend on the dose (low doses enhance dopamine activity, while high doses inhibit it)

Applications

Treatment of schizophrenia and psychotic disorders

Adjunct therapy for depression (off-label use)

Investigated for use in gastroprokinetic and mood stabilization therapies

Side Effects

Common Side Effects

eizures or epilepsy

Special Considerations

Pregnancy & Breastfeeding – Should only be used if clearly needed, as it may affect the baby.

Elderly Patients – Increased risk of stroke and other complications.

Alcohol & Other Sedatives – Can enhance drowsiness and dizziness.

Diabetes & Metabolic Concerns – May affect blood sugar levels and weight.

 

 

Additional Information:

• Item Code: SHREEJI1
• Delivery Time: Immediate
• Packaging Details: HDPE DRUM PACK

Product Details:

 

We are offering high quality of Rivaroxaban. We are known for manufacturing,exporting,distributing, trading and supplying Rivaroxaban in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Rivaroxaban in Gujarat. India. Shreeji Pharma International manufacturing &amp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Rivaroxaban Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Rivaroxaban as well as Intermediates of Rivaroxaban.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Rivaroxaban to countries like Gulf Countries,South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries.

Rivaroxaban is a synthetic, orally active anticoagulant used in the prevention and treatment of thromboembolic disorders. It belongs to a class of drugs known as direct oral anticoagulants (DOACs) or non-vitamin K antagonist oral anticoagulants (NOACs) and functions by selectively inhibiting Factor Xa, a crucial enzyme in the blood coagulation cascade.

Rivaroxaban (CAS No. 366789-02-8) is a direct oral anticoagulant (DOAC) that acts as a selective inhibitor of Factor Xa, playing a crucial role in the prevention and treatment of thromboembolic disorders. Below is a detailed technical overview of Rivaroxaban powder, focusing on its chemical properties, specifications, and applications:
Molecular Formula: C₁₉H₁₈ClN₃O₅S
Molecular Weight: 435.88 g/mol
Appearance: White to light yellow crystalline powder
Melting Point: 230–234°C
Specific Rotation: -40.0° to -44.0° (C=1, DMSO)
Solubility:Practically insoluble in water Soluble in dimethylformamide (DMF)
Slightly soluble in organic solvents like acetone and polyethylene glycol 400
Optical Activity: [α]D -34 to -44 (c = 0.3 in DMSO)
Purity (HPLC): ≥98.0%
Assay: 98.0% – 102.0% (anhydrous substance)
Total Impurities: ≤0.3%
Single Impurity: ≤0.1%
Loss on Drying: ≤0.5%
Residue on Ignition: ≤0.1%
Heavy Metals: ≤20 ppm
Specific Optical Rotation: 39° to -42°
Structural & Functional Insights
Enantiomer: Pure (S)-enantiomer
Polymorphism: Crystallizes in three polymorphs; Polymorph I is the thermodynamically stable form used in tablet formulations
Stability: Air and heat-sensitive; store under inert gas and refrigerated (0–10°C)
Storage Conditions: Refrigerated (2–8°C); store in tightly sealed containers away from light and moisture
Mechanism of Action : Rivaroxaban inhibits Factor Xa, a key enzyme in the coagulation cascade, thereby reducing thrombin generation and preventing clot formation. It is highly selective for Factor Xa, with an IC₅₀ of 0.7 nM, and shows no activity against thrombin, trypsin, plasmin, or other coagulation factors up to 20 µM .

 

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We are offering high quality of Travoprost. We are known for manufacturing, exporting, distributing, trading and supplying Travoprost. in Gujarat, India. Further, this is safely Packaged by our professionals in diverse packaging options that maintain its purity and Effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Travoprost in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Travoprost Nowadays Shreeji Pharma International is one of the leading manufacturer And exporter, who is manufacturing Bimatoprost as well as Intermediates of Travoprost.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Travoprost to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries 

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We are offering high quality of Dicloxacillin sodium .We are known for manufacturing, exporting, distributing, trading and supplying Dicloxacillin sodium In Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of  Dicloxacillin sodium  in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Dicloxacillin sodium  Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Dicloxacillin sodium  as well as Intermediates of Dicloxacillin sodium.Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Dicloxacillin sodium to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Introduction of product: Dicloxacillin is a narrow-spectrum β-lactam antibiotic of the penicillin class. It is used to treat infections caused by susceptible (non-resistant) Gram-positive bacteria. It is active against beta-lactamase-producing organisms such as Staphylococcus aureus, which would otherwise be resistant to most penicillins.
Technical specifications: - 
CAS. No.  13412-64-1
Synonyms : 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolyl Penicillin Sodium Salt Monohydrate; Dichlorstapenor Sodium; Dicloxacillin Sodium Hydrate
Chemical Name   : (2S,5R,6R)-6-[[[3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt hydrate
Molecular Formula  :  C19H16Cl2N3NaO5S·H2O
Molecular Weight  :  510.32 g/mol
How does it work:Dicloxacillin is in a class of medications called penicillins. It works by killing bacteria. Antibiotics such as dicloxacillin will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.
Applications. : Dicloxacillin is a β-lactamase resistant penicillin similar to oxacillin. Dicloxacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. It is resistant to penicillinase.
How to use :  Take this medication by mouth usually 4 times a day (every 6 hours), or as directed by your doctor. Take dicloxacillin on an empty stomach (1 hour before or 2 hours after a meal) with a full glass of water. Drink plenty of fluids while using this medication unless your doctor tells you otherwise.The dosage is based on your medical condition and response to therapy.For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same time(s) every day.Continue to take this medication until the full-prescribed amount is finished even if symptoms disappear after a few days.
Side effects  :: Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Warnings and precautions while using this product::Severe diarrhea (watery, possibly with blood)If you are pregnant or breast feeding, talk with your doctor before taking this medicine.

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We are offering high quality of Carbamazepine.We are known for manufacturing, exporting, distributing, trading and supplying Carbamazepine in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Carbamazepine in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Carbamazepine owadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing  Carbamazepine as well as Intermediates of Carbamazepine.Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Carbamazepine to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Carbamazepine is a medication commonly used to treat a variety of conditions, including epilepsy, bipolar disorder, trigeminal neuralgia, and sometimes restless leg syndrome. It works by stabilizing electrical activity in the brain and nerves.
Here’s a detailed description:
1. Pharmacological Classification:
Anticonvulsant: It’s primarily used to treat seizures and epilepsy, including partial and tonic-clonic seizures.
Mood Stabilizer: It is also used to manage mood swings in bipolar disorder, helping to prevent manic and depressive episodes.
Analgesic (Pain Reliever): It is used in treating trigeminal neuralgia, a condition involving nerve pain in the face.
2. Mechanism of Action:
Sodium Channel Blockade: Carbamazepine works by inhibiting voltage-gated sodium channels in neurons. This prevents the repetitive firing of neurons and helps to stabilize electrical activity, reducing seizures and abnormal nerve activity.
Effect on Neurotransmitters: It also modulates neurotransmitter systems, such as decreasing the release of excitatory neurotransmitters like glutamate, which can contribute to both seizures and mood instability.
3. Indications:
Epilepsy: Effective for focal (partial) seizures and generalized tonic-clonic seizures.
Bipolar Disorder: Used to control manic episodes and as a mood stabilizer.
Trigeminal Neuralgia: Often prescribed for this specific type of facial pain caused by nerve dysfunction.
Other Uses: Sometimes used for other conditions like restless leg syndrome or certain types of neuropathic pain.
4. Dosage:
The dosage of carbamazepine varies depending on the condition being treated and the patient’s response. It is typically started at a low dose and gradually increased to minimize side effects.
It is available in oral tablets, extended-release tablets, oral suspension, and sometimes chewable tablets.
5. Side Effects:
Common: Dizziness, drowsiness, nausea, and uncoordinated movements.
Serious Side Effects:
Blood Disorders: Carbamazepine can cause a decrease in blood cell counts, including leukopenia (low white blood cell count), aplastic anemia, and thrombocytopenia (low platelets).
Rash: A serious rash can develop, and in rare cases, it can progress to Stevens-Johnson syndrome, which is life-threatening.
Liver Toxicity: Liver function should be monitored, as it can cause liver damage.Hyponatremia (Low Sodium Levels): This can lead to symptoms like confusion, weakness, and nausea.
6. Precautions:
Allergies: People with a known hypersensitivity to carbamazepine or similar medications (such as phenytoin) should not take it.

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Sodium Cocoamphoacetate POWDER

We are offering high quality of Sodium Cocoamphoacetate POWDER. We are known for manufacturing, exporting, distributing, trading and supplying Sodium Cocoamphoacetate POWDER in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Sodium Cocoamphoacetate POWDER in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Sodium Cocoamphoacetate POWDER. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Sodium Cocoamphoacetate POWDER as well as Intermediates of Sodium Cocoamphoacetate POWDER.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Sodium Cocoamphoacetate POWDER to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Sodium Cocoamphoacetate is a mild amphoteric surfactant derived from coconut oil fatty acids. It is commonly used in personal care and cosmetic products due to its gentle cleansing, foaming, and conditioning properties. It is a preferred ingredient in baby shampoos, facial cleansers, and sulfate-free formulations because of its mildness and biodegradability.

 Chemical & Physical Properties

Chemical Name: Sodium Cocoamphoacetate

CAS Number: 68334-21-4

Molecular Formula: C₂₀H₄₀N₂NaO₄

Molecular Weight: Approx. 398 g/mol

Appearance: White to off-white powder

Odor: Mild characteristic odor

Solubility: Readily soluble in water

pH (10% aqueous solution): 6.0 – 8.5

Density: Approx. 1.05 g/cm³

Foaming Properties: Produces a rich, stable foam

Biodegradability: Fully biodegradable

 

Storage & Handling

Store in a cool, dry place, away from moisture.

Keep in a sealed container to prevent clumping.

Shelf Life: 2 – 3 years under proper storage conditions.

Conclusion

Sodium Cocoamphoacetate Powder is a mild, eco-friendly surfactant widely used in gentle cleansing formulations. It is ideal for baby care, personal care, and sulfate-free products due to its non-irritating and biodegradable properties.

 

 

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We are offering high quality of Ferric Pyrophosphate Powder. We are known for manufacturing, exporting, distributing, trading and supplying Ferric Pyrophosphate Powder in maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Ferric Pyrophosphate Powder in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Ferric Pyrophosphate Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Ferric Pyrophosphate Powder as well as Intermediates of Ferric Pyrophosphate Powder.  

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Shreeji Pharma International currently export Ferric Pyrophosphate Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Ferric Pyrophosphate (Fe4(P2O7)3) is an iron-containing compound often used in various industrial and pharmaceutical applications. Here's a detailed description of it:

Chemical Structure and Composition

Ferric Pyrophosphate is composed of ferric (Fe³⁺) ions combined with pyrophosphate ions (P2O7)⁴⁻. Its molecular formula is Fe₄(P₂O₇)₃.

It appears as a dark brown or black powder.

Properties:

Appearance: Dark brown to black powder.

Molecular weight: Approximately 415.74 g/mol.

Solubility: It is generally insoluble in water, which makes it useful in slow-release applications, especially in fertilizers or supplements.

Stability: Ferric pyrophosphate is relatively stable under normal conditions, but its stability can vary depending on the environment, especially under acidic or alkaline conditions.

Uses and Applications:

Iron Supplementation:

Ferric Pyrophosphate is used in iron fortification of foods, particularly for populations with iron-deficiency anemia.

It is also employed in medical treatments to address iron deficiency, often as part of intravenous iron formulations.

In some cases, it is found in oral iron supplements due to its ability to provide a form of iron that is less likely to cause gastrointestinal side effects compared to other forms of iron salts.

Agriculture:

It is used in fertilizers as a source of iron for plants. Since it is insoluble, it provides a slow-release form of iron, helping prevent iron deficiency in plants over time.

Industrial Applications:

It is also used in various industrial processes, including catalysis, due to its chemical properties.

Cosmetics and Personal Care:

Ferric Pyrophosphate can be used in some cosmetic formulations, particularly those that target hair or skin health through the delivery of iron.

Health and Safety:

Toxicity: Ferric pyrophosphate is generally considered safe when used in approved doses, but like other iron compounds, excessive intake can lead to iron toxicity. Always follow recommended dosage guidelines for any supplement or treatment.

Environmental Impact: As a stable, insoluble compound, it tends not to pose a major environmental risk. However, any iron compound should be handled carefully to avoid contamination of water sources or excessive accumulation in soil.

Benefits in Iron Fortification:

Compared to other iron salts, ferric pyrophosphate offers a lower risk of gastrointestinal irritation, making it a preferred choice in some iron supplementation programs.

 

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We are offering high quality of Nitazoxanide API Powder. We are known for manufacturing, exporting, distributing, trading and supplying Nitazoxanide API Powder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Nitazoxanide API Powder in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Nitazoxanide API Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Nitazoxanide API Powder as well as Intermediates of Nitazoxanide API Powder.  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Nitazoxanide API Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Uses: Nitazoxanide is used to treat diarrhea in children and adults caused by the protozoa Cryptosporidium or Giardia. Protozoa are suspected as the cause when diarrhea lasts more than 7 days. Nitazoxanide is in a class of medications called antiprotozoal agents.

1. General Information

Chemical Name: Nitazoxanide

Molecular Formula: C12H9N3O5S

Molecular Weight: 307.28 g/mol

CAS Number: 55981-09-4

IUPAC Name: 2-(Acetylamino)-N-(5-nitro-2-thiazolyl)benzamide

Appearance: Yellow to light yellow crystalline powder

Solubility: Practically insoluble in water; soluble in dimethyl sulfoxide (DMSO) and slightly soluble in ethanol

Melting Point: Approximately 202–208°C

Stability: Stable under normal storage conditions but should be kept away from moisture and direct sunlight

2. Pharmacological Properties

Class: Broad-spectrum antiparasitic and antiviral agent

Mode of Action:

Inhibits the pyruvate-ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction, essential for anaerobic energy metabolism in parasites and bacteria

Also exhibits antiviral properties by interfering with viral replication mechanisms

3. Applications

Antiparasitic Uses:

Effective against protozoal infections such as Giardia lamblia and Cryptosporidium parvum

Used to treat intestinal parasitic infections, including amoebiasis

Effective against Helicobacter pylori in combination with other agents

Antiviral Uses:

Investigated for activity against rotavirus, norovirus, and other viral gastroenteritis pathogens

Studied for potential applications in treating hepatitis B and C, influenza, and coronaviruses

Antibacterial Uses:

Shows efficacy against Clostridium difficile and other anaerobic bacteria

4. Manufacturing and Quality Standards

Purity: ≥98% (as per pharmacopoeial standards)

Loss on Drying: ≤1.0%

Residue on Ignition: ≤0.5%

Heavy Metals: ≤10 ppm

Assay: 98.0% – 102.0%

5. Storage and Handling

Storage Conditions: Store in a cool, dry place, protected from light and moisture

Shelf Life: Typically 2–3 years when stored under appropriate conditions

Packaging: Available in 1 kg, 5 kg, and 25 kg drums with double-layer polyethylene inner bags

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• Item Code: 55981-09-4
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We are offering high quality of Acriflavine Hcl. We are known for manufacturing, exporting, distributing, trading and supplying Acriflavine Hcl in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Acriflavine Hcl in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of 4 N Hexyl Resorcinol. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Acriflavine Hclas well as Intermediates of 4 N Hexyl Resorcinol.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Acriflavine Hclto countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Acriflavine HCl is a synthetic dye and antiseptic belonging to the acridine family. It has antimicrobial and antiviral properties and is commonly used in microbiology, aquaculture, and research applications.

Chemical Details:

Chemical Name: Acriflavine Hydrochloride

CAS Number: 8063-24-9

Molecular Formula: C14H14ClN3

Molecular Weight: ~ 259.73 g/mol

Appearance: Orange-red to reddish-brown crystalline powder

Solubility: Soluble in water and alcohol

pH: Slightly acidic in solution

Uses & Applications:

Antiseptic & Disinfectant: Used for wound cleaning and bacterial infection prevention.

Microbiology: Employed as a selective agent in bacterial culture media.

Aquaculture: Used to treat bacterial and fungal infections in fish.

Research: Investigated for anticancer and antiviral properties.

DNA Staining: Acts as an intercalating agent in molecular biology studies.

Storage & Handling:

Storage Conditions: Keep in a tightly sealed container, away from light and moisture.

Handling Precautions: Use gloves, safety goggles, and protective clothing. Avoid direct skin and eye contact.

Safety & Hazards:

Toxicity: Can be harmful if ingested, inhaled, or absorbed through the skin.

Environmental Impact: Toxic to aquatic life; avoid uncontrolled disposal.

First Aid Measures: In case of contact, rinse with plenty of water and seek medical attention if necessary.

Precautions:

Handling & Storage:

Store in a cool, dry place, away from direct sunlight and moisture.

Use gloves and protective eyewear when handling to avoid irritation.

Avoid inhalation or ingestion; it can be toxic in large amounts.

Health Hazards:

May cause skin and eye irritation.

Can stain the skin and clothing.

Prolonged exposure may cause allergic reactions.

Environmental Impact:

Avoid discharging into water sources as it may affect aquatic life.

Dispose of according to local environmental regulations.

First Aid Measures:

Skin Contact: Wash with soap and water immediately.

Eye Contact: Rinse thoroughly with water for at least 15 minutes.

Inhalation: Move to fresh air and seek medical help if breathing difficulties occur.

Ingestion: Do not induce vomiting; seek immediate medical attention.

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We are offering high quality of Lithium Carbonate Powder. We are known for manufacturing, exporting, distributing, trading and supplying Lithium Carbonate Powder  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Lithium Carbonate Powder  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Lithium Carbonate Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Lithium Carbonate Powder as well as Intermediates of Lithium Carbonate Powder.   Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Lithium Carbonate Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries

Lithium Carbonate Powder – Detailed Description

Overview

Lithium Carbonate (Li₂CO₃) is an inorganic compound widely used in various industries, including pharmaceuticals, ceramics, glass manufacturing, batteries, and metallurgy. It appears as a white, odorless crystalline powder that is water-soluble and stable under normal conditions.

Chemical & Physical Properties

Chemical Formula: Li₂CO₃

Molecular Weight: 73.89 g/mol

Appearance: White crystalline powder

Solubility:

Soluble in water (~1.54 g/100 mL at 20°C)

Slightly soluble in alcohol

Insoluble in acetone

Density: ~2.11 g/cm³

Melting Point: 723°C (decomposes)

Boiling Point: Decomposes before boiling

pH (in water): ~11 (alkaline nature)

Applications

Battery Industry:

Used as a precursor in lithium-ion battery production.

Integral in manufacturing lithium cobalt oxide (LiCoO₂) and lithium iron phosphate (LiFePO₄) cathodes.

Pharmaceuticals:

Used in the treatment of bipolar disorder as a mood stabilizer.

Regulates neurotransmitter activity in the brain.

Glass & Ceramics:

Reduces thermal expansion, improving the strength of glass and ceramics.

Enhances the melting properties of glazes in ceramic manufacturing.

Aluminum Processing:

Acts as an additive in aluminum smelting processes to improve efficiency.

Other Industrial Uses:

Employed in cement and concrete additives.

Utilized in carbon dioxide absorption in various chemical processes.

Safety & Handling

Hazards:

Can be harmful if ingested in large amounts.

Prolonged exposure may cause skin and eye irritation.

May affect the nervous system if inhaled in excessive amounts.

Handling Precautions:

Use personal protective equipment (PPE), including gloves, safety glasses, and a dust mask.

Store in a cool, dry, well-ventilated area away from acids.

Avoid inhalation of dust and direct contact with skin.

First Aid Measures:

Inhalation: Move to fresh air, seek medical attention if symptoms persist.

Skin Contact: Wash thoroughly with soap and water.

Eye Contact: Rinse with plenty of water for at least 15 minutes and seek medical attention.

Ingestion: Do not induce vomiting; seek medical advice immediately.

 

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We are offering high quality of Afoxolaner. We are known for manufacturing, exporting, distributing, trading and supplying Afoxolaner in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Afoxolaner in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Afoxolaner. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Afoxolaner as well as Intermediates of Afoxolaner.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the
Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Afoxolaner to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Afoxolaner is an ectoparasiticide belonging to the isoxazoline class. It is commonly used as an active ingredient in veterinary medicine, particularly in flea and tick treatments for dogs. Afoxolaner works by inhibiting the γ-aminobutyric acid (GABA)-gated chloride channels, leading to paralysis and death of the parasites. It is commonly formulated as chewable tablets for oral administration.

Technical Details:

Chemical Name: 1-(5,6-Dihydro-5-[[(5S)-5-phenyl-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]methyl]-4H-[1,2,4]triazol-3-yl)-N-methyl-2-naphthamide

Molecular Formula: C26H17F3N4O3

Molecular Weight: 566.43 g/mol

Mode of Action:Selectively binds to GABA-gated and glutamate-gated chloride channels in fleas and ticks.
Causes hyperexcitation of the nervous system, leading to paralysis and death of parasites.Rapid onset of action, typically killing fleas within 8 hours and ticks within 48 hours.

Usage: Used primarily in dogs for the prevention and treatment of flea and tick infestations.Administered orally as a chewable tablet, usually once a month.

Precautions:Species-Specific Use:Approved for dogs only; not recommended for cats or other animals unless prescribed.

Contraindications:Should not be used in dogs with known hypersensitivity to afoxolaner.

Side Effects: Possible gastrointestinal issues (vomiting, diarrhea).Rare cases of neurological reactions (tremors, ataxia, seizures).
Use in Pregnant or Lactating Dogs:Safety in pregnant, breeding, or lactating dogs has not been fully established.

Interactions: Should be used with caution in dogs with a history of seizures.

Absorption: Rapidly absorbed after oral administration.
Distribution: High bioavailability with distribution into tissues.
Metabolism: Primarily metabolized in the liver.

Excretion: Excreted via feces and urine, with a half-life of approximately 14 days in dogs.

Uses & Indications
Used in veterinary medicine as an oral ectoparasiticide in dogs.

Kills and prevents infestations of fleas (Ctenocephalides spp.) and ticks (Dermacentor spp., Rhipicephalus sanguineus, Ixodes spp.).

Used in combination products for broader parasitic control (e.g., NexGard, NexGard Spectra).

Dosage & Administration

Given orally, typically in flavored chewable tablets.

Dosage: 2.5 mg/kg body weight monthly for flea and tick control.
Safe for dogs over 8 weeks of age and weighing more than 2 kg.

Safety & Adverse Effects
Generally well tolerated, but may cause mild side effects: Vomiting,Diarrhea,Lethargy,Anorexia

Caution in dogs with epilepsy, as it may lower the seizure threshold.

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