Established in the year2004, we, “Shreeji Pharma International”, are one of the leading manufacturers, exporters and suppliers of a range ofPharmaceutical Products. The offered range is formulated using superior quality ingredients, which are procured from the most reliable vendors of the market. These products possess features like safe consumption, accurate composition, precise pH value and non-toxic. The entire range is demanded by our clients for curing various diseases, ailments and health problems.
We have established a state-of-the-art, which is spread across a vast stretch of land situated atVadodarain the state ofGujarat,India. This infrastructure is segregated into various units that are equipped with modern machines and latest technology. All the units are manned by a team of professionals, who are well-experienced in their respective domain. These professionals make sure that the entire production process is undertaken following strict quality standards. Our logistics personnel strive hard to deliver the ordered consignments at clients doorsteps within the given period of time. Further, we have been able to gain trade membership withPharmexcil, IDMAthat has enabled us to serve numerous patrons across theSouth/West Africa, East Europe, East Asia, Central Americaand many more.
Product Details:
| Minimum Order Quantity | 25 Kg |
| Grade Standard | USP |
| Physical State | Powder |
| Usage | PHARMA |
| Packaging Type | DRUM |
| Country of Origin | Made in India |
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kg |
| Grade Standard | USP |
| Prescription/Non prescription | Prescription |
| Type of API | Vitamin Powder API |
| Packaging Type | HDPE drum |
| Packaging Size | 25kgs |
| Shelf life | 5 years |
| Form | powder |
| Country of Origin | Made in India |
We are offering high quality of Calcium Glycerophosphate We are known for manufacturing ,exporting, distributing, trading and supplying Calcium Glycerophosphate in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Calcium Glycerophosphate in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Calcium Glycerophosphate onwadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Calcium Glycerophosphate as well as Intermediates of Calcium Glycerophosphate.Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Calcium Glycerophosphateto countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries.
Calcium Glycerophosphate is a chemical compound that is primarily used as a calcium supplement. It is a salt formed from calcium and glycerophosphate, a derivative of glycerol. The chemical formula for calcium glycerophosphate is typically written as Ca(C3H7O6P)2. Here's a detailed description of its characteristics and uses:
Chemical Structure and Properties
Molecular Formula: Ca(C3H7O6P)2
Solubility: Slightly soluble in water, though it dissolves more readily in acidic conditions.
Stability: Stable under normal conditions, but sensitive to moisture and may clump if not stored properly.
Main Uses
Calcium Supplement: Calcium glycerophosphate is commonly used as a supplement to provide the body with calcium, which is essential for bone health, muscle function, and nerve transmission. The glycerophosphate component helps in the absorption of calcium in the body.
Dental Care: It is used in some toothpaste formulations, especially those designed to improve enamel remineralization. Calcium glycerophosphate may help in preventing tooth decay and strengthening tooth enamel by supplying calcium ions that can integrate into the tooth surface.
Food Additive: In some cases, calcium glycerophosphate is used as a food additive, where it can act as a calcium fortifier in products like milk substitutes or other calcium-fortified foods.
Pharmaceutical Applications: Besides being a dietary supplement, calcium glycerophosphate is also found in various pharmaceutical formulations aimed at treating or preventing calcium deficiency in patients.
Benefits
Supports Bone Health: As a source of calcium, calcium glycerophosphate can help prevent or treat conditions like osteoporosis and calcium deficiency.
Improves Dental Health: It can help in remineralizing teeth and preventing dental erosion.
Better Calcium Absorption: The glycerophosphate part of the compound helps facilitate calcium absorption more efficiently than some other forms of calcium.
Safety and Side Effects
Calcium glycerophosphate is generally considered safe when used as directed in supplements and other products. However, excessive intake can lead to side effects associated with high calcium levels, such as kidney stones, constipation, or hypercalcemia.
As with any supplement, it is important to follow recommended dosages and consult with a healthcare provider before starting any new supplement regimen.
Other Considerations
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kg |
| Grade Standard | USP |
| Packaging Type | Drum |
| Prescription/Non prescription | Non prescription |
| Type of API | Blood System and Cardiovacular API |
| Dosage Form (If Applicable) | Powder form |
| Product Type | API |
| Shelf life | 5 YEARS |
| Usage | Pharma use |
| Country of Origin | Made in India |
| Chemical Name | N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate |
| Melting Point | 104-108 DegreeC (maleate salt) |
We are offering high quality of Pheniramine Maleate. We are known for manufacturing, exporting, distributing, trading and supplying Pheniramine Maleate in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Pheniramine Maleate in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Pheniramine Maleate. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Pheniramine Maleate as well as Intermediates of Pheniramine Maleate.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently exports Pheniramine Maleate to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
1. General Information: Chemical Name: Pheniramine Maleate, Chemical Formula: C16H20N2.C4H4O4, Molecular Weight: 356.4 g/mol, CAS Number: 132-20-7, Appearance: White or off-white crystalline powder, Solubility: Soluble in water, ethanol, and chloroform
2. Pharmacological Classification: Drug Class: First-generation antihistamine, Mechanism of Action: Pheniramine Maleate is an H₁-receptor antagonist that blocks histamine activity.
It reduces allergic responses such as sneezing, itching, and hives by preventing histamine from binding to its receptors.
3. Applications & Uses: Medical Uses:Treatment of allergic conditions like hay fever, rhinitis, urticaria, and conjunctivitis, Relief from cold symptoms, such as sneezing and runny nose, Used in combination with other medications for cough and flu treatment, Mild sedative properties, sometimes used to aid sleep, Treatment of motion sickness and nausea
Veterinary Uses: Used in animals for treating allergic reactions, skin conditions, and respiratory issues
Industrial & Research Uses: Pharmaceutical formulations for antihistamine drugs, Used in laboratory research for studying histamine responses
4. Dosage & Administration: Human Dosage (General Guide): Typical oral dose: 25 mg to 50 mg, taken every 6 to 8 hours, depending on severity, Maximum daily dose: 150 mg, Available in tablets, capsules, syrups, and injections, Veterinary Dosage: Dosage varies depending on species and weight. Consult a veterinarian before use.
5. Side Effects: Common Side Effects: Drowsiness, dizziness, dry mouth, blurred vision
Nausea, vomiting, constipation, Severe Side Effects (Rare but serious): Increased heart rate (tachycardia), Difficulty urinating, Severe allergic reactions (swelling, rash, breathing difficulties)
Additional Information:
Product Details:
| Packaging Type | Drum |
| Physical State | Powder |
| Grade Standard | Pharma Grade |
| CAS Number | 129-16-8 |
| Pack size | 25 |
| Packaging Size | 25 kg |
| Brand | Shreeji |
| Shelf life | 5 years |
| Form | Powder |
| Usage/Application | Commerical |
| Country of Origin | Made in India |
We are offering high quality of Meropenem Sodium We are known for manufacturing, exporting, distributing, trading and supplying Meropenem Sodium in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Meropenem Sodium in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Meropenem Sodium .Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Meropenem Sodium as well as Intermediates of Meropenem Sodium .Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Meropenem Sodium countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries. Meropenem sodium is an antibiotic used primarily to treat a variety of bacterial infections. It belongs to the class of medications known as carbapenems, which are broad-spectrum beta-lactam antibiotics. Here's a detailed description: General Description: Chemical Name: Meropenem sodium
Molecular Formula: C17H25N3O5S
Mechanism of Action: Meropenem works by inhibiting bacterial cell wall synthesis, leading to cell death. It does this by binding to penicillin-binding proteins (PBPs) on the bacterial cell membrane, interfering with the final step of cell wall synthesis, which is crucial for bacterial survival.Spectrum of Activity: Meropenem has a broad spectrum of activity, effective against a wide range of both Gram-positive and Gram-negative bacteria, including some multi-drug resistant organisms. It also covers anaerobic organisms.
Indications:Meropenem is typically prescribed for severe or complicated infections, including:
Intra-abdominal infections (e.g., peritonitis)
Meningitis
Severe pneumonia, including hospital-acquired and ventilator-associated pneumonia
Urinary tract infections (complicated)
Sepsis
Skin and soft tissue infections
Bone and joint infections
Febrile neutropenia (fever due to infection in immunocompromised patients)
Pharmacokinetics:
Route of Administration: Usually administered intravenously (IV) or via deep intramuscular injection.
Half-life: Approximately 1 hour.
Distribution: It is widely distributed in the body, including to the cerebrospinal fluid (CSF), making it effective for treating infections like meningitis.
Metabolism: Meropenem is minimally metabolized in the liver and is primarily excreted unchanged in the urine.
Excretion: About 70-75% of the drug is excreted via the kidneys.
Dosage:
Adult dose: Typically, 500 mg to 1 g every 8 hours, depending on the infection's severity and the patient’s renal function.
Pediatric dose: Dosing varies depending on the child’s age, weight, and type of infection.
Side Effects:
Common side effects may include:
Diarrhea
Nausea
Vomiting
Rash
Infusion site reactions (pain, swelling)
Serious but less common side effects may include:
Severe allergic reactions (e.g., anaphylaxis)
Additional Information:
Product Details:
| Minimum Order Quantity | 25 kilogram |
| Packaging Type | Sack |
| Physical State | Powder |
| Grade Standard | Industrial Grade |
| Shelf life | 5 years |
| Form | powder |
| Country of Origin | Made in India |
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kg |
| Grade Standard | USP |
| Brand | Shreeji Pharma |
| Type of API | Anti Infective API |
| Prescription/Non prescription | Prescription |
| Shelf life | 60 Months |
| Form | Powder |
| Composition | Insoluble in water and alcohol,soluble in acid and alkali. |
| Packaging Size | 25 Kg,50 Kg |
We are offering high quality of Aluminium Hydroxide Gel. We are known for manufacturing, exporting, distributing, trading and supplying Aluminium Hydroxide Gel in Gujarat India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Aluminium Hydroxide Gel in Gujarat India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Aluminium Hydroxide Gel. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Aluminium Hydroxide Gel as well as Intermediates of Aluminium Hydroxide Gel.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Aluminium Hydroxide Gel to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
1. General Information
Chemical Name: Aluminium Hydroxide
Molecular Formula: Al(OH)₃
CAS Number: 21645-51-2
Appearance: White, amorphous powder
Solubility: Practically insoluble in water and alcohol
Odor: Odorless
Taste: Slightly astringent
2. Physical & Chemical Properties
pH (5% slurry): 5.5 – 8.0
Loss on Drying: Typically ≤ 8%
Bulk Density: 0.4 – 0.6 g/cm³
Specific Surface Area: High surface area for adsorption properties
Particle Size: Fine powder for uniform dispersion
3. Uses & Applications
Pharmaceuticals:Used as an antacid to neutralize stomach acid and treat conditions like acid reflux and gastritis.Also used in combination with magnesium hydroxide or simethicone for better therapeutic effects.
Industrial Applications:Used as a flame retardant filler in plastics, rubber, and coatings.Component in ceramics and glass manufacturing. Water purification applications.
Applications:
Pharmaceutical Use:Used as an antacid to neutralize stomach acid in medications.Acts as a phosphate binder in renal failure treatments.Incorporated in vaccine formulations as an adjuvant.
Industrial & Chemical Use:Utilized in fire retardant materials.Used as a thickening and stabilizing agent in various formulations.Applied in water purification and wastewater treatment.
Keep the container tightly closed to avoid contamination.
Store away from acids and incompatible substances (e.g., strong oxidizers).
Safety Precautions:
Avoid inhalation: Use in a well-ventilated area or wear a mask if handling large quantities.
Avoid skin and eye contact: Wear gloves and safety goggles when handling.
Prevent ingestion (unless prescribed for medicinal use).
First Aid Measures:
Inhalation: Move to fresh air; seek medical help if breathing difficulty occurs.
Skin Contact: Wash with soap and water.
Eye Contact: Rinse immediately with water for at least 15 minutes and seek medical attention if irritation persists.
Ingestion (Non-Medical Use): Rinse mouth, drink water, and seek medical advice if symptoms appear.
Medical Use Precautions:
Follow doctor’s prescription for treating acidity, ulcers, or kidney-related conditions.
Avoid long-term or excessive use, as it may cause phosphate depletion or aluminum toxicity (especially in kidney patients).
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kg |
| Prescription/Non prescription | Non prescription |
| Packaging Type | drum |
| Usage/Application | pharma |
| Packaging Size | 100g |
| Form | Powder |
| Shelf Life | 3 year |
| Is It Organic | Not Organic |
| Origin | india |
| Is It Dried | Dried |
| Country of Origin | Made in India |
| CAS Number | 31828-71-4 |
We are offering high quality of Mexiletine HCl .We are known for manufacturing, exporting, distributing, trading and supplying Mexiletine HCl in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Mexiletine HCl in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Mexiletine HCl . Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Mexiletine HCl as well as Intermediates of Mexiletine HCl . Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Mexiletine HCl countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Mexiletine Hydrochloride (Mexiletine HCl) Technical Details
1. General Information
IUPAC Name: 1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride
Chemical Formula: C11H17NO · HCl
Molecular Weight: 215.72 g/mol
CAS Number: 31828-71-4
2. Mechanism of Action
Mexiletine HCl is a class 1B antiarrhythmic agent that works by blocking voltage-gated sodium channels (Na⁺ channels) in cardiac muscle, reducing abnormal electrical activity.
It shortens the action potential duration and reduces the refractory period, helping to suppress ventricular arrhythmias.
It also has analgesic effects by modulating sodium channels in the nervous system.
3. Indications
Cardiac Uses: Treatment of ventricular arrhythmias (e.g., premature ventricular contractions, ventricular tachycardia).
Neurological Uses: Off-label for neuropathic pain syndromes, including diabetic neuropathy and chronic pain syndromes (e.g., myotonia congenita).
4. Pharmacokinetics
Absorption: Well-absorbed orally; bioavailability ~90%.
Distribution: Binds minimally to plasma proteins (~50%).
Metabolism: Hepatic metabolism via CYP2D6, producing inactive metabolites.
Elimination Half-life: ~10-12 hours.
Excretion: Primarily renal (~90% as metabolites).
5. Dosage & Administration
Ventricular Arrhythmias:
Initial dose: 200 mg every 8 hours
Maintenance dose: 200–300 mg every 8 hours
Max dose: 1,200 mg/day
Neuropathic Pain (off-label):
150–200 mg twice daily, adjusted based on response.
6. Adverse Effects
Common: Nausea, dizziness, tremors, palpitations, GI upset.
Serious: QT prolongation, hypotension, liver enzyme elevation, seizures (rare).
7. Contraindications
Hypersensitivity to mexiletine
Cardiogenic shock
Severe heart block (without a pacemaker)
Severe liver dysfunction
8. Drug Interactions
CYP2D6 inhibitors (e.g., fluoxetine, quinidine) may increase mexiletine levels.
Beta-blockers & other antiarrhythmics may increase risk of bradycardia or hypotension.
Caffeine & theophylline clearance may be reduced, leading to toxicity.
Additional Information:
Product Details:
| Physical State | Powder |
| Usage/Application | Pharma |
| Dose/Strength (ex. 1 mg or 1 ml) | As prescribed by Physician |
| Grade Standard | USP |
| Usage | Hospital, PHARMA, Clinical |
| Shelf Life | 5 YEARS |
| Country of Origin | Made in India |
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kg |
| Purity | 99.9% |
| Grade | USP(Pharma) Grade |
| Packaging Type | DRUM PACK |
| Appearance | white or off-white granular powder |
| Melting Point | 206 DegreeC (dec.)(lit.) |
| Boiling Point | 673.6 DegreeC at 760 mmHg |
| Grade Standard | pharma |
| Physical State | Powder |
| Usage | Commerical |
| Country of Origin | Made in India |
We are offering high quality of Sodium Gluconate. We are known for manufacturing, exporting, distributing, trading and supplying Sodium Gluconate in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Sodium Gluconate in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Sodium Gluconate. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Sodium Gluconate as well as Intermediates of Sodium Gluconate.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently exports Sodium Gluconate to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Sodium Gluconate is the sodium salt of gluconic acid, a non-toxic, biodegradable, and water-soluble compound. It is widely used as a chelating agent, pH regulator, sequestrant, stabilizer, and corrosion inhibitor in food, pharmaceuticals, construction, water treatment, and industrial applications.
Property Specification
Chemical Name :Sodium Gluconate
Molecular Formula: C₆H₁₁NaO₇
Molecular Weight :218.14 g/mol
CAS Number :527-07-1
Appearance :White crystalline powder or granules
Odor Odorless
Solubility : Highly soluble in water, insoluble in alcohol
pH (1% solution, 25°C) 6.5 – 8.5
Density 1.8 – 2.0 g/cm³
Melting Point > 206°C (decomposes)
Biodegradability > 98% (readily biodegradable)
Sequestrant & Stabilizer: Prevents discoloration and spoilage in food.
pH Regulator: Maintains acidity in food and beverage formulations.
Preservative Alternative: Used in dairy, processed foods, and baked goods.
Common Uses:
pH Buffer in Medications
Calcium & Iron Supplement Enhancer
Electrolyte Solutions in IV Fluids
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kg |
| Grade Standard | USP |
| Packaging Size | 25 kgs |
| Purity | 99% |
| Usage | Clinical |
| Packaging Type | Drum |
| Manufacturer | shreeji |
| CAS Number | 86393 32 0 |
| Chemical Formula | C17H19ClFN3O3 |
| Shelf life | 5 years |
| Molecular weight | 367.8 g/mol |
| Form | powder |
| Country of Origin | Made in India |
| Formula | C14H23Cl2N3O2 |
| Presentation | White Powder |
| Chemical Class | Pharmaceuticals |
| CAS Number: | 7232-21-5 |
We are offering high quality of Metoclopramide Hydrochloride.We are known for manufacturing, exporting, distributing, trading and supplying Metoclopramide Hydrochloride in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Metoclopramide Hydrochloride in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Metoclopramide Hydrochloride. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Metoclopramide Hydrochloride as well as Intermediates of Metoclopramide Hydrochloride. Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Metoclopramide Hydrochloride countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Metoclopramide Hydrochloride: Detailed Description
1. Overview
Metoclopramide Hydrochloride is a dopamine antagonist that enhances gastrointestinal motility and is commonly used for treating nausea, vomiting, and gastroparesis. It works by blocking dopamine receptors in the brain and gut, increasing gastric emptying and reducing reflux.
2. Mechanism of Action
Blocks dopamine D2 receptors in the chemoreceptor trigger zone (CTZ) of the brain, reducing nausea and vomiting.
Enhances acetylcholine release in the gastrointestinal tract, increasing peristalsis and promoting gastric emptying.
Increases lower esophageal sphincter tone, helping with gastroesophageal reflux disease (GERD).
3. Indications (Uses)
Gastrointestinal Disorders
Diabetic gastroparesis (delayed stomach emptying)
Gastroesophageal reflux disease (GERD)
Postoperative nausea and vomiting (PONV)
Chemotherapy-induced nausea and vomiting (CINV)
Diagnostic Procedures
Used to enhance barium meal transit in radiographic studies.
4. Dosage & Administration
Oral Tablets & Liquid: 5 mg to 10 mg, up to 4 times daily (before meals and at bedtime).
Intravenous (IV) & Intramuscular (IM): Used in hospitals for acute nausea/vomiting or pre-procedure preparations.
Pediatric Dosage: Based on body weight (0.1–0.15 mg/kg per dose).
5. Side Effects
Common Side Effects:Drowsiness,Fatigue,Restlessness,Diarrhea
Serious Side Effects (Rare):
Extrapyramidal Symptoms (EPS): Muscle spasms, tremors, dystonia
Tardive Dyskinesia (TD): Involuntary facial movements (long-term use risk)
Neuroleptic Malignant Syndrome (NMS): Fever, confusion, muscle rigidity (rare but serious)6. Contraindications
Epilepsy or seizures (increases risk of convulsions)
Gastrointestinal obstruction, perforation, or bleeding
Parkinson’s disease (dopamine blockade worsens symptoms)
Chemical Information:
IUPAC Name: 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide hydrochloride
Molecular Formula: C14H22ClN3O2·HCl
Molecular Weight: 354.3 g/mol
CAS Number: 7232-21-5 (Metoclopramide Hydrochloride)
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kg |
| Packaging Size | 25 kg |
| Grade | Pharmaceutical Grade |
| CAS Number | 1185-57-5 |
| Color | Brown |
| Form | Powder |
| Usage/Application | Pharmaceutical Industry |
| Chemical Formula | C6H11FeNO7 |
| Molecular Weight | 261.98 g/mol |
Product Details:
| Minimum Order Quantity | 25 Kg |
| Prescription/Non prescription | Prescription |
| Packaging Size | 25,50 kgs |
| Pack Size | 25 kg.HDPE drum/bags |
| CAS Number | 546-46-3 |
| Form | powder |
| pH Value | PH (1% aqueous solution) 6.0-7.0 |
| Shelf Life | 5 YEARS |
| Country of Origin | Made in India |
We are offering high quality of Zinc Citrate . We are known for manufacturing, exporting, distributing, trading and supplying Zinc Citrate in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Zinc Citrate in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Zinc Citrate . Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Zinc Citrate as well as Intermediates of Zinc Citrate .
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Zinc Citrate to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Zinc Citrate is a compound that combines zinc, an essential mineral, with citric acid. It is one of the more commonly used forms of zinc in dietary supplements due to its relatively high bioavailability and gentler effect on the digestive system compared to other zinc salts, such as zinc sulfate. Zinc citrate is widely utilized for its health benefits, particularly for supporting the immune system, skin health, and cellular function.
1. Chemical Structure:
IUPAC Name: Zinc citrate
Molecular Formula: C6H6O7Zn\text{C}_6 \text{H}_6 \text{O}_7 \text{Zn}C6H6O7Zn
Molar Mass: Approximately 287.5 g/mol
Structure: Zinc citrate consists of one zinc ion (Zn²⁺) bound to two molecules of citric acid, an organic acid found naturally in fruits such as citrus. The citric acid acts as a ligand, stabilizing the zinc ion and making it more bioavailable for absorption in the body.
2. Properties:
Solubility: Zinc citrate is water-soluble, making it easily absorbable by the gastrointestinal tract. The solubility of zinc citrate is beneficial for its use in supplements, as it ensures that the zinc can be readily utilized by the body.
Mild on the Stomach: Zinc citrate is often preferred over other zinc salts, like zinc sulfate, because it tends to be gentler on the stomach and less likely to cause gastrointestinal discomfort, such as nausea or irritation.
3. Bioavailability:
Zinc citrate is known for its good bioavailability, meaning that it is efficiently absorbed into the bloodstream when consumed. The citric acid component helps facilitate the absorption of zinc in the small intestine, making it a suitable choice for individuals looking to boost their zinc levels through supplementation.
4. Benefits of Zinc Citrate:
Zinc is an essential trace mineral that plays numerous vital roles in the body. Zinc citrate offers all the benefits of zinc with the added advantage of improved absorption and tolerance.
Key Health Benefits:
Immune System Support: Zinc is crucial for the proper function of the immune system. It helps in the development and activation of T-lymphocytes (T-cells), which are essential for immune responses. Zinc also has antiviral properties and helps reduce the severity and duration of colds.
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kg |
| Prescription/Non prescription | Non prescription |
| Usage | pellets capsule |
| Physical State | Granules |
| Packaging Size | 25kg drum pack |
| Grade Standard | pharma pellets |
| Packaging Type | drum |
| Color | white |
| Pharmacopoeial Status | BP / USP / EP |
| Country of Origin | Made in India |
We are offering high quality of Metformin HCL We are known for manufacturing, exporting, distributing, trading and supplying Metformin HCL in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Metformin HCL in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Metformin HCL .Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Metformin HCL as well as Intermediates of Metformin HCL .Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Metformin HCL countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Methenamine Hippurate: Detailed Description
1. Overview
Methenamine hippurate is an antibacterial agent used to prevent and suppress urinary tract infections (UTIs). It is not an antibiotic in the traditional sense but works by acidifying the urine, which converts methenamine into formaldehyde, a substance that kills bacteria.
2. Chemical and Pharmacological Properties
Generic Name: Methenamine Hippurate
Drug Class: Urinary anti-infective
Chemical Formula: C₁₅H₂₂N₂O₆
Mechanism of Action:
Methenamine is hydrolyzed in acidic urine (pH < 6) to produce formaldehyde, which has a broad antibacterial effect.
Hippuric acid acts as a urinary acidifier to enhance the effect of methenamine.
3. Uses and Indications
Prevention & suppression of recurrent UTIs (e.g., caused by E. coli, Proteus, Enterococcus).
Often used for long-term prophylaxis in individuals prone to recurrent infections.
It is not used for active infections—a separate antibiotic is typically needed for acute UTI treatment.
4. Dosage & Administration
Adults and children over 12 years: 1 g (two 500 mg tablets) twice daily.
Children (6-12 years): 500 mg twice daily.
Taken with plenty of fluids to ensure proper urine flow and effectiveness.
5. Contraindications & Precautions
Contraindications:
Severe renal impairment (kidneys must function to excrete methenamine properly).
Severe hepatic impairment (risk of ammonia accumulation).
Metabolic acidosis disorders.
Precautions:
Requires acidic urine to be effective (pH should be < 6).
Avoid use with medications that alkalize urine (e.g., some antacids, carbonic anhydrase inhibitors).
6. Side Effects
Common: Nausea, stomach upset, dysuria (painful urination).
Less common: Rash, hematuria (blood in urine), bladder irritation.
Rare but serious: Allergic reactions, crystalluria (crystals in urine).
7. Drug Interactions
Urinary Alkalinizers: Reduce effectiveness (e.g., sodium bicarbonate, acetazolamide).
Sulfonamides: May react with formaldehyde, increasing the risk of crystalluria.
8. Special Considerations
Pregnancy: Generally considered safe (Category C).
Breastfeeding: Limited data; consult a doctor.
Elderly Patients: Monitor kidney function closely.
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kg |
| Grade Standard | USP |
| Packaging Size | 25 kg |
| Purity | 99% |
| Prescription/Non prescription | Prescription |
| Form | Powder |
| Grade | pharma |
| Country of Origin | Made in India |
We are offering high quality of Ornidazole. We are known for manufacturing, exporting, distributing, trading and supplying Ornidazole in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Ornidazole in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Ornidazole. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Ornidazole as well as Intermediates of Ornidazole.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently exports Ornidazole to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
1. Overview: Ornidazole is a nitroimidazole derivative with potent antiprotozoal and antibacterial properties. It is widely used to treat infections caused by anaerobic bacteria and protozoa, including amoebiasis, giardiasis, trichomoniasis, and certain bacterial infections.
2. Chemical & Physical Properties: IUPAC Name: 1-(3-chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole, Molecular Formula: C7H10ClN3O3, Molecular Weight: 219.63 g/mol, Appearance: White or yellowish crystalline powder
3. Mechanism of Action: Ornidazole acts by penetrating bacterial and protozoal cells and disrupting their DNA structure by forming toxic metabolites. This leads to inhibition of nucleic acid synthesis, resulting in cell death.
4. Pharmacokinetics: Absorption: Rapidly absorbed after oral administration, Bioavailability: High (≥90%), Peak Plasma Concentration: Achieved within 3–4 hours, Half-life: 12–14 hours (longer than metronidazole), Metabolism: Metabolized in the liver
5. Indications: Ornidazole is used to treat a variety of anaerobic bacteria and protozoal infections, including:
6. Dosage & Administration:Dosage depends on the condition being treated:
Amoebiasis: Adults: 1.5 g once daily or 500 mg twice daily for 5–10 days, Children: 10–25 mg/kg/day for 5–10 days, Giardiasis: Adults: 1.5 g as a single dose, Children: 40 mg/kg as a single dose
7. Side Effects: Gastrointestinal Issues: Nausea, vomiting, diarrhea, metallic taste
8. Contraindications: Hypersensitivity to nitroimidazoles, Pregnancy (especially first trimester)
9. Drug Interactions: Increased risk of bleeding,CYP450 Inhibitors/Inducers: May alter ornidazole metabolism
10. Comparison with Metronidazole
|
Feature |
Ornidazole |
Metronidazole |
|
Half-life |
12–14 hours |
6–8 hours |
|
Dosing frequency |
Less frequent |
More frequent |
|
Taste |
Less metallic |
More metallic |
|
Side effects |
Fewer neurological effects |
More neurological effects |
|
CNS Penetration |
High |
High |
11. Special Precautions: Avoid alcohol during and after treatment (up to 3 days), Use with caution in patients with liver dysfunction, Monitor for neurological symptoms if used long-term, 12. Forms Available: Tablets: 250 mg, 500 mg, Suspension: 125 mg/5 mL, IV Injection: 500 mg/100 mL
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kg |
| Packaging Type | 25 KGS |
| Shelf life | 5 years |
| Purity % | 99-95% |
| Physical State/Form | Powder |
| Packaging Size | 25 kg |
| Grade Standard | BP,USP |
| Form | Powder |
| Uses | Pharma |
| Country of Origin | Made in India |
We are offering high quality of Propyl Paraben . We are known for manufacturing, exporting, distributing, trading and supplying Propyl Paraben in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Propyl Paraben in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Propyl Paraben . Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Propyl Paraben as well as Intermediates of Propyl Paraben .
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently exports Propyl Paraben to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Propyl Paraben, also known as propyl 4-hydroxybenzoate, is a widely used antimicrobial preservative in various industries, including food, pharmaceuticals, and cosmetics. It is an ester of p-hydroxybenzoic acid, produced by esterifying p-hydroxybenzoic acid with n-propanol using an acid catalyst.
Chemical Name: Propyl Paraben (Propyl p-Hydroxybenzoate)
CAS Number: 94-13-3
Molecular Formula: C₁₀H₁₂O₃
Molecular Weight: 180.20 g/mol
Physical Properties:
Appearance: White crystalline powder or colorless crystals
Odor: Odorless or faintly aromatic
Density: Approximately 1.06 g/cm³
Melting Point: 95°C–98°C
Boiling Point: Decomposes before boiling
Solubility:
Slightly soluble in water (~0.05 g/100 mL at 20°C)
Soluble in ethanol, methanol, acetone, and other organic solvents
Propyl Paraben exhibits antimicrobial activity by disrupting microbial cell membranes, inhibiting the growth of bacteria and fungi. Its effectiveness increases with the length of the ester chain, but solubility decreases, making lower esters like methyl and propyl paraben more practical for use.
Food Industry: Used as a preservative in processed foods, beverages, and dairy products to extend shelf life by preventing microbial growth.
Cosmetic Industry: Commonly added to creams, lotions, shampoos, makeup, and deodorants to prevent spoilage.
Pharmaceutical Industry: Incorporated into oral and topical medications, injections, and ophthalmic solutions as a preservative.
Personal Care Products: Found in sunscreens, toothpaste, mouthwash, and shaving products to maintain product integrity.Regulatory Status:Propyl Paraben has been approved for use in foods by the US Food and Drug Administration (FDA). The Joint FAO/WHO Expert Committee on Food Additives has set an acceptable daily intake for the sum of ethyl, methyl, and propyl esters of p-hydroxybenzoic acid at 10 mg/kg.
Safety Considerations:
While Propyl Paraben is generally considered safe, it may cause allergic reactions in some individuals. Concerns have been raised about its potential estrogenic activity, but current evidence linking parabens to health risks like cancer is considered weak. Despite this, consumer perception has led to increased demand for paraben-free products.
Storage: Store in a cool, dry, and well-ventilated area, ideally at 15°C–25°C. Keep in tightly sealed, moisture-resistant containers away from strong oxidizing agents, acids, bases, moisture, heat, and direct sunlight.
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kg |
| Grade Standard | USP |
| Chemical Formula | C21H27ClN2O2 |
| Prescription/Non prescription | Non prescription |
| Manufacturing Process | Chemical Synthesis |
| Molecular Weight | 374.9 g/mol |
| Type of API | Antipyretic and Analgesic API |
| Usage | Industrial |
| Packaging Size | 25 kgs |
| Shelf life | 3 years |
| Therapeutic Area | Gastrointestinal Disorders |
| API Form | Powder |
We are offering high quality of Hydroxyzine HCL. We are known for manufacturing, exporting, distributing, trading and supplying Hydroxyzine HCL in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Hydroxyzine HCL in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Hydroxyzine HCL. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Hydroxyzine HCL as well as Intermediates of Hydroxyzine HCL.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Hydroxyzine HCL to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Hydroxyzine HCL is a first-generation antihistamine with a range of uses, including treatment of anxiety, nausea, allergies, and insomnia, as well as serving as a sedative. Here are the technical details:
Chemical Information:
IUPAC Name: 2-[2-(4-chlorophenyl)ethoxy]ethanamine hydrochloride
Molecular Formula: C21H27ClN2·HCl
Molecular Weight: 374.87 g/mol
CAS Number: 58-35-9
Synonyms: Atarax, Vistaril, Anxan, Meprospan
2. Common Uses
Anxiety Relief: Often prescribed to manage anxiety or tension, especially for short-term use.
Allergy Symptoms: Hydroxyzine can treat allergy symptoms like hives, itching, or rashes.
Nausea and Vomiting: It is used to treat nausea or vomiting, including post-surgery.
Sleep Disorders: Hydroxyzine can be used short-term to help with sleep issues, particularly if related to anxiety or stress.
Preoperative Sedation: It is used as a sedative before surgery to calm patients.
3. Mechanism of Action
Histamine Blockade: Hydroxyzine works by blocking the effects of histamine, a chemical involved in allergic reactions and the regulation of sleep-wake cycles.
CNS Depression: It has a central nervous system depressant effect, which accounts for its sedative and calming properties.
4. Dosage Forms
Tablets: Available in oral tablet form for ease of use.
Syrup: Available as an oral syrup for easier administration, especially for children.
Injectable: Hydroxyzine can be given by injection in hospital settings for more immediate effects.
5. Side Effects
Common side effects may include:
Drowsiness or sedation (common and expected)
Dry mouth
Dizziness
Blurred vision
Constipation
Headache
Serious side effects (less common but requiring medical attention):
Rapid or irregular heartbeats
Allergic reactions (rash, itching, swelling)
Difficulty breathing
6. Precautions and Warnings
Avoid Alcohol: Hydroxyzine may increase the sedative effects of alcohol, leading to severe drowsiness and impaired coordination.Pregnancy and Breastfeeding: Use cautiously during pregnancy, especially in the first trimester. It is excreted in breast milk, so it should be avoided during breastfeeding unless prescribed by a healthcare provider.
Hydroxyzine is often prescribed as a short-term solution for anxiety or other issues, due to its potential for drowsiness and dependence on regular use.
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kg |
| Grade Standard | USP |
| Purity | 99% |
| Packaging | 25Kg Bag |
| CAS Number | 89796-99-6 |
| Grade | Pharma Grade |
| Chemical Formula | C16H13Cl2NO4 |
| Molecular Weight | 354.1847 g/mol |
| Boiling Point | 486.0+-45.0 DegreeC |
| Melting Point | 149-153 DegreeC |
| Country of Origin | Made in India |
We are offering high quality of AceclofenacWe are known for manufacturing, exporting,distributing, trading and supplying Aceclofenacin in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Aceclofenacin Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of 4 N Hexyl Resorcinol. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Aceclofenacas well as Intermediates of 4 N Hexyl Resorcinol.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Aceclofenacto countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
1. Introduction:Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) widely used for the relief of pain and inflammation associated with various conditions, including rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is known for its effective analgesic and anti-inflammatory properties.
2. Chemical Information:
Chemical Name: 2-[(2,6-Dichlorophenyl)amino]phenylacetoxyacetic acid
Molecular Formula: C16H13Cl2NO4
Molecular Weight: 354.19 g/mol
CAS Number: 89796-99-6
Appearance: White or off-white crystalline powder
Solubility: Soluble in methanol, ethanol, and slightly soluble in water.
3. Mode of Action:
Aceclofenac works by inhibiting the action of cyclooxygenase (COX) enzymes, specifically COX-2, which are responsible for the production of prostaglandins (chemical messengers causing pain and inflammation).
4. Uses and Indications:
Osteoarthritis: Relieves pain and inflammation in joints.
Rheumatoid arthritis: Manages symptoms of inflammation, swelling, and joint stiffness.
Ankylosing spondylitis: Used for managing pain and inflammation in spinal arthritis.
Postoperative pain and trauma: Effective in reducing post-surgical pain and inflammation.
5. Dosage Form:
Tablets: 100 mg, 200 mg (commonly available in combination with Paracetamol or Serratiopeptidase).
Topical Gel: Applied locally to reduce inflammation.
Injection: Used in acute pain management (less common).
6. Side Effects:Nausea, vomiting,Abdominal pain, indigestion,Dizziness, headache,Skin rash or itching
Severe Side Effects:Gastrointestinal bleeding,Liver function abnormalities,Allergic reactions (anaphylaxis, skin reactions),Kidney dysfunction
7. Precautions and Warnings:
Pregnancy: Not recommended during pregnancy, especially in the third trimester.
Lactation: Should be avoided during breastfeeding unless absolutely necessary.
Kidney/Liver Impairment: Dose adjustment or monitoring may be required in patients with renal or hepatic dysfunction.
Cardiovascular Risk: Prolonged use may increase the risk of cardiovascular events like heart attack or stroke.
Gastrointestinal Risk: Long-term use can cause ulcers, bleeding, or perforation in the stomach or intestines.
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kg |
| Grade Standard | BP |
| Purity | 99% |
| Grade | Pharma Grade |
| Packaging Type | Drum |
| Dose/Strength (ex. 1 mg or 1 ml) | As prescribed by physician |
| Usage | Hospital, Clinical |
| Color | White |
| Shelf life | 5 years |
| Country of Origin | Made in India |
Quinine Sulphate Powder is the sulfate salt form of quinine, which is a naturally occurring alkaloid derived from the bark of the Cinchona tree. It has been used for centuries in the treatment of malaria, and while its primary application remains in malaria therapy, it also has other uses in certain medical conditions.
Key Uses:Malaria Treatment and Prevention: Quinine sulfate is one of the key drugs used for treating malaria caused by Plasmodium falciparum and other species of the parasite. It is typically used in combination with other anti-malarial medications like doxycycline or clindamycin to ensure effectiveness and reduce the chances of resistance.
Leg Cramps: Quinine sulfate has historically been used to treat nocturnal leg cramps, though it is generally not recommended for this use due to safety concerns. The U.S. FDA has restricted its use for this purpose due to side effects such as serious cardiovascular issues, including arrhythmias.
Other Off-label Uses: In some cases, quinine sulfate may be used off-label for conditions like babesiosis (a malaria-like parasitic infection) or for certain types of arrhythmias, but these uses are less common.
Side Effects: Quinine can cause a range of side effects, including nausea, dizziness, hearing loss, tinnitus (ringing in the ears), and visual disturbances. In severe cases, quinine may cause more serious side effects like allergic reactions, low blood sugar (hypoglycemia), or even life-threatening conditions such as cinchonism (a syndrome caused by quinine overdose or toxicity).
Drug Interactions: Quinine sulfate can interact with several medications, including anticoagulants (e.g., warfarin), anti-arrhythmic drugs, and other medications that affect the heart’s rhythm. Patients should always inform their healthcare providers of all drugs they are taking.
Dosage: The dosage of quinine sulfate can vary depending on the condition being treated. For malaria, it is often administered in combination with other drugs, and the specific regimen is determined by the healthcare provider. For leg cramps (though generally discouraged), doses may range, but it’s important to be aware that the FDA no longer approves quinine for this purpose.
Contraindications: Quinine should not be used in people with certain conditions, such as those with pre-existing heart issues (like arrhythmias), certain types of liver or kidney disease, or a history of allergic reactions to quinine.
Quinine sulfate is typically available in the form of tablets, capsules, or oral powder. In some cases, it can also be administered intravenously for severe malaria.
If you're considering the use of quinine sulfate powder, it’s essential to consult with a healthcare provider to ensure it’s safe and appropriate for your condition.
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kg |
| Grade Standard | USP |
| Purity | 99% |
| Packaging Size | 25 Kg |
| Dose/Strength (ex. 1 mg or 1 ml) | As prescribed by physician |
| Usage | Clinical, Hospital |
| Packaging Type | Sack |
| Color | White |
We are offering high quality of Terbinafine Hcl Powder. We are known for manufacturing, exporting, distributing, trading and supplying Terbinafine Hcl Powder in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Terbinafine Hcl Powder in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Terbinafine Hcl Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Terbinafine Hcl Powder as well as Intermediates of Terbinafine Hcl Powder.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Terbinafine Hcl Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Terbinafine Hydrochloride (HCl) is an antifungal medication primarily used to treat fungal infections, particularly those of the skin and nails. It is effective against a broad spectrum of fungal pathogens, including dermatophytes, yeasts, and molds. Terbinafine HCl is available in several forms, including oral tablets, topical creams, and ointments. Below is a detailed description of Terbinafine Hydrochloride.
Chemical Name:(E)-N-(6,6-dimethyl-2-hepten-4-yl)-N-methyl-1-naphthalenemethanamine hydrochloride
Molecular Formula:C21H25N•HCl
Molecular Weight:295.89 g/mol
CAS Number:78628-80-5 (Terbinafine Hydrochloride)
Description:
Terbinafine is a synthetic allylamine antifungal agent used to treat various fungal infections. The hydrochloride (HCl) form of terbinafine is commonly used in oral formulations. It works by inhibiting an enzyme called squalene epoxidase, which is essential for the synthesis of ergosterol — a crucial component of the fungal cell membrane. By disrupting the fungal cell membrane, terbinafine leads to the death of the fungus.
Terbinafine is broad-spectrum, meaning it is effective against a wide range of fungi, including dermatophytes (fungi that cause skin, hair, and nail infections), yeasts (such as Candida), and molds.
Physical Appearance:
Form: White to off-white crystalline powder.
Appearance in Solution: It is usually available as a white crystalline powder for oral tablets or topical formulations.
Solubility:
Poorly soluble in water, but soluble in alcohol and chloroform.
8. Mechanism of Action:
Squalene Epoxidase Inhibition: Terbinafine works by inhibiting the enzyme squalene epoxidase, which is involved in the synthesis of ergosterol, a key component of the fungal cell membrane. Without ergosterol, the integrity of the fungal cell membrane is compromised, leading to cell death.
Unlike some other antifungal drugs, terbinafine does not inhibit cytochrome P450 enzymes in human cells, reducing the risk of drug interactions.
Storage:
Oral Tablets: Store in a cool, dry place, away from light and moisture, at room temperature (20–25°C or 68–77°F).
Topical Creams/Ointments: Store in a cool, dry place, away from direct sunlight, at room temperature (15–30°C or 59–86°F).
Do not freeze any form of terbinafine.
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kilogram |
| Packaging Size | 25,50 kg |
| Packaging Type | Bag,Drum |
| Product Type | API |
| Pack Size | DRUM PACK |
| Cas Number | 14281-83-5 |
| Shelf Life | 5 YEARS |
| Country of Origin | Made in India |
| Application | Industrial |
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kg |
| Physical State | Powder |
| Color | White |
| Package Type | Drum |
| CAS Number | 5793-88-4 |
| Formula | C6H10 O8 . Ca |
| Molecular Weight | C6H8 |
| Synonym | Glucaricacid,calcium salt (11),D- (8CI); Antacidin; Calcium D-glucarate; CalciumD-saccharate; Cal |
| API Form | Powder |
We are offering high quality of Calcium D-SaccharateWe are known for manufacturing ,exporting, distributing, trading and supplying Calcium D-Saccharatein Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Calcium D-Saccharatein Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Calcium D-Saccharateonwadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Calcium D-Saccharateas well as Intermediates of Calcium D-Saccharate.Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Calcium D-Saccharateto countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries.
Calcium Saccharate is a calcium salt of saccharic acid (also known as saccharate), commonly used as a calcium supplement in various applications, including in the food industry and as a dietary supplement. Here's a detailed breakdown:
1. Chemical Structure and Composition
Chemical Formula: C12H22CaO14It is a calcium salt derived from saccharic acid, which is a sugar-derived organic acid. Saccharate is the product of oxidation of sugars like glucose, where the aldehyde group is converted into a carboxyl group.
2. Physical Properties
Appearance: It typically appears as a white or off-white crystalline powder.Solubility: It is soluble in water, which makes it useful in various liquid-based formulations.
Taste: Calcium saccharate is generally considered tasteless or has a slightly sweet flavor due to the saccharic acid component.3. Uses and Applications
Dietary Supplement: Calcium saccharate is used as a source of calcium in dietary supplements. Calcium is an essential mineral for bone health, muscle function, and various biochemical processes in the body.
Food Industry: It can be used in food processing as a calcium fortifying agent. It is especially useful in products aimed at providing calcium without altering the taste or texture significantly.Pharmaceuticals: Sometimes it is incorporated into pharmaceutical formulations to provide astable source of calcium in liquid medications or syrups.
4. Benefits of Calcium Saccharate
Bone Health: As a source of calcium, it supports bone and dental health.
Calcium Absorption: Calcium saccharate, being soluble in water, is relatively easy for the body to absorb, making it a convenient option for calcium supplementation.
Non-Irritating: Unlike some other calcium salts, calcium saccharate is often less irritating to the gastrointestinal system.
5. Safety and Dosage
It is generally regarded as safe when used as directed in dietary supplements and food products.The recommended dosage varies depending on the age and specific health needs of the individual. However, excessive intake of calcium can lead to adverse effects, such as kidney stones or hypercalcemia (excess calcium in the blood).
6. Other InformationSynthesis: Calcium saccharate can be synthesized through a process where calcium is reacted with saccharic acid or its derivatives.
Storage: It should be stored in a cool, dry place to maintain its stability and prevent any degradation.
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kg |
| Grade Standard | BP |
| Packaging Size | 5 kg |
| Prescription/Non prescription | Prescription |
| Usage/Application | pharma |
| Treatment | Application: Ivabradine Hydrochloride is a selective bradycardic agent. CAS Number: 148849-67-6. |
| Shelf life | 3 years |
| Brand | Shreeji Pharma |
| API Form | Powder |
We are offering high quality of Ivabradine Hydrochloride. We are known for manufacturing, exporting, distributing, trading and supplying Ivabradine Hydrochloride in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Ivabradine Hydrochloride in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Ivabradine Hydrochloride. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Ivabradine Hydrochloride as well as Intermediates of Ivabradine Hydrochloride is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Ivabradine Hydrochloride to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
vabradine Hydrochloride is a medication primarily used to treat certain heart conditions, particularly those related to the heart's electrical system. Here’s a detailed description:
Chemical Composition and Formulation
Chemical Name: Ivabradine Hydrochloride
Molecular Formula: C26H36N2O4S·HCl
Ivabradine hydrochloride is the hydrochloride salt form of ivabradine, which belongs to a class of drugs known as If channel inhibitors. It specifically inhibits the If (funny) current in the sinoatrial node (the heart's natural pacemaker), which helps regulate the heart rate.
Therapeutic Uses
Chronic Stable Angina: Ivabradine is used in the treatment of chronic stable angina (a type of chest pain caused by reduced blood flow to the heart), particularly in patients who cannot tolerate beta-blockers or for whom beta-blockers are contraindicated.
Heart Failure: It is also used in heart failure, specifically for patients with systolic heart failure who have a heart rate ≥ 70 beats per minute, despite optimal medical therapy. Ivabradine reduces hospitalizations due to heart failure and improves heart function.
Sinus Tachycardia: Ivabradine may be used to manage certain cases of sinus tachycardia, where the heart rate is abnormally high due to an overactive sinoatrial node.
Pharmacokinetics
Absorption: Ivabradine is well-absorbed when taken orally, but its bioavailability is somewhat low due to first-pass metabolism.
Metabolism: Ivabradine is metabolized primarily in the liver by cytochrome P450 enzymes (particularly CYP3A4).
Side Effects: Common side effects of ivabradine include:
Bradycardia (slow heart rate): The most notable side effect, as ivabradine directly impacts the heart's rate.
Visual disturbances: Temporary phosphenes (visual phenomena like flashes of light) are seen in some patients. This occurs due to ivabradine’s effects on the retinal pacemaker cells.
Headache, Dizziness or light-headedness
Additional Information:
Product Details:
| Minimum Order Quantity | 25 Kg |
| Grade Standard | PHARMA |
| Manufacturing Process | Chemical Synthesis |
| Physical State | Powder |
| Packaging Type | Drum |
| Pack Size | 25kgs |
| Shelf life | 12 months |
| Country of Origin | Made in India |
We are offering high quality of Sildenafil Citrate We are known for manufacturing,exporting, distributing, trading and supplying Sildenafil Citrate in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Sildenafil Citrate in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Sildenafil Citrate Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Sildenafil Citrate as well as Intermediates of Sildenafil Citrate .Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Sildenafil Citrate to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries.
- Technical Specifications :
Description: Potent PDE5 inhibitor; orally active
Chemical Name: 1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate
M. Wt : 666.7
Formula : C22H30N6O4S.C6H8O7
Storage : Desiccate at RT
Purity : ≥99% (HPLC)
CAS Number : 171599-83-0
- Introduction of product :Sildenafil citrate is an orally active, potent inhibitor of phosphodiesterase 5 (PDE5) (IC50 = 4 nM). Enhances nitric oxide-dependent relaxation of human corpus cavernosum in vitro. Sildenafil citrate promotes mobilization of hematopoietic stem cells (HSCs) in combination with AMD 3100 (Cat. No. 3299).
- How does it work? :Sildenafil works by preventing the action of a chemical in your body, called phosphodiesterase type-5. This helps to widen (relax) blood vessels and improves the flow of blood to the penis following sexual stimulation. This helps to maintain an erection.
- Applications. Or where it is used :Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. It is unclear if it is effective for treating sexual dysfunction in women. It is taken by mouth or by injection into a vein.
- Manufacturing process :The first step of the synthesis is the reaction of a diketoester (1) and hydrazine to give the pyrazole ring. The regioselective N-methylation of the pyrazole and hydrolysis gives a carboxylic acid (3). Compound (3) is then reacted with HNO3 and H2SO4 to give a nitrated product.
- How to use :Take sildenafil as needed before sexual activity. The best time to take sildenafil is about 1 hour before sexual activity, but you can take the medication any time from 4 hours to 30 minutes before sexual activity. Sildenafil usually should not be taken more than once every 24 hours.
- Side effects :flushing (warmth, redness, or tingly feeling);headache, dizziness;heartburn, nausea, or upset stomach.abnormal vision (blurred vision, changes in color vision),runny or stuffy nose, nosebleeds;sleep problems (insomnia); or.muscle pain, back pain.
- Warnings and precautions while using this product :Sildenafil should not be used with any other medicine or device that causes erections. It is important to tell your doctor about any heart problems you have now or may have had in the past.
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