Active Pharmaceuticals Ingredient 3

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We are offering high quality of Lamotrigine  Powder Api. We are known for manufacturing, exporting, distributing, trading and supplying Lamotrigine  Powder Api  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Lamotrigine  Powder Api  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Lamotrigine  Powder Api. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Lamotrigine  Powder Api as well as Intermediates of Lamotrigine  Powder Api.  Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Lamotrigine  Powder Api to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.Lamotrigine is an anticonvulsant medication primarily used to treat epilepsy and bipolar disorder. It helps stabilize electrical activity in the brain and is often prescribed for long-term management of seizures and mood disorders.

General Information

Brand Names: Lamictal, Lamictal XR, Lamictal ODT, Lamictal CD

Drug Class: Anticonvulsant, Mood Stabilizer

Formulations: Tablets, chewable tablets, orally disintegrating tablets, extended-release tablets

Prescription Required: Yes
Uses

Epilepsy (Seizure Disorders):Used as monotherapy or adjunct therapy for focal (partial) seizures, generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome.

Helps prevent recurrence of seizures by stabilizing electrical activity in the brain.

Bipolar Disorder :Approved for the maintenance treatment of bipolar I disorder to help prevent depressive and manic episodes.

Unlike some mood stabilizers, it is more effective at preventing depressive episodes rather than acute manic episodes.Mechanism of Action Lamotrigine works by inhibiting voltage-gated sodium channels in the brain, which reduces excessive electrical activity that can cause seizures or mood swings. It also modulates the release of neurotransmitters like glutamate and aspartate, helping stabilize mood in bipolar disorder.

Dosage & Administration

The dosage varies based on the condition being treated, age, and other medications being taken.

It is usually started at a low dose and gradually increased to reduce the risk of serious side effects.

Typical starting dose:

For epilepsy: 25 mg once daily for 2 weeks, then gradually increased.

For bipolar disorder: 25 mg once daily for 2 weeks, then increased over several weeks.

It can be taken with or without food but should be taken consistently the same way.

Side Effects

Common Side Effects: Headache, Dizziness,Nausea, Sleep disturbances (insomnia or drowsiness) , Blurred vision , Tremors

Serious Side Effects: 

Stevens-Johnson Syndrome (SJS) & Toxic Epidermal Necrolysis (TEN): Severe skin reactions that require immediate medical attention.

Aseptic Meningitis: Symptoms include fever, stiff neck, nausea, and headaches.

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• Delivery Time: IMMEDIATE
• Packaging Details: HDPE DRUM PACK

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We are offering high quality of Glucosamine Hcl powder. We are known for manufacturing, exporting, distributing, trading and supplying Glucosamine Hcl powder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

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Shreeji Pharma International currently export Glucosamine Hcl powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Glucosamine Hydrochloride (HCl) is a compound often used as a dietary supplement for joint health, particularly to alleviate the symptoms of osteoarthritis. Below are the technical details of Glucosamine HCl:

1. Chemical Structure and Formula:

Chemical Name: 2-Amino-2-deoxy-D-glucose hydrochloride

Molecular Formula: C6H13NO5 · HCl

Molecular Weight: Approximately 227.64 g/mol

CAS Number: 31284-96-5 (Glucosamine Hydrochloride)

2. Physical Properties:

Appearance: White to off-white crystalline powder

Solubility: Soluble in water

Melting Point: Approximately 160–165°C

pH: Around 4.5 to 6.5 (in aqueous solution)

Stability: Stable under standard storage conditions, though it should be kept away from direct sunlight and moisture.

Sources of Glucosamine

Glucosamine is naturally found in the body, specifically in cartilage, and is often extracted from the shells of shellfish, such as shrimp, crabs, and lobsters, to make supplements. It is also available in synthetic forms. Some plant-based forms of glucosamine have been developed for vegetarians, though they are less common.

Health Benefits of Glucosamine

Joint Health & Osteoarthritis: The most common use of glucosamine supplements is to manage symptoms of osteoarthritis, a degenerative joint disease that causes pain and stiffness. Some studies have shown that glucosamine sulfate may help reduce joint pain, improve joint function, and slow cartilage deterioration.

Pain Relief: Glucosamine is believed to support the maintenance of healthy cartilage and the reduction of inflammation, which can help reduce pain and stiffness in the joints, particularly in the knees, hips, and spine.

Support for Cartilage Repair: Since glucosamine is a component of cartilage, it is thought to play a role in supporting the repair and rebuilding of damaged cartilage, especially in individuals suffering from joint wear and tear.

Anti-inflammatory Properties: There is some evidence that glucosamine has anti-inflammatory effects, which can reduce swelling and discomfort in joints affected by conditions like osteoarthritis.

Potential for Treating Other Conditions: Research is still ongoing, but some studies suggest that glucosamine may have potential benefits for other health conditions, such as inflammatory bowel disease, temporomandibular joint (TMJ) disorders, and even promoting skin health.

 

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• Delivery Time: PROMPT
• Packaging Details: 25KG DRUM

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We are offering high quality of Furosemide Powder. We are known for manufacturing, exporting, distributing, trading and supplying Furosemide Powder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Furosemide Powder  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Furosemide Powder

Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Furosemide Powder as well as Intermediates of Furosemide Powder.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Furosemide Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Furosemide is a potent loop diuretic commonly used to treat conditions involving fluid retention, such as heart failure, chronic kidney disease, cirrhosis, and hypertension. Here are some key technical details about furosemide:

Chemical Information

IUPAC Name: 4-chloro-N-furfuryl-5-sulphamoyl-2-aminobenzoic acid

Molecular Formula: C12H11ClN2O5S

Molecular Weight: 330.75 g/mol

CAS Number: 54-31-9Key Uses:

Edema: Furosemide is used to treat fluid retention caused by conditions such as heart failure, liver disease (cirrhosis), kidney disease, and other medical conditions that cause the body to hold on to extra fluid.

Hypertension: It can also be used to help lower blood pressure, often as part of a treatment plan for high blood pressure.

Dosage

The dosage of furosemide varies based on the condition being treated, the severity of the condition, and the patient’s response. The typical starting dose for adults is usually:

Side Effects

Furosemide can cause several side effects, some of which can be serious:

Dehydration: As a potent diuretic, it can cause the body to lose too much fluid.

Electrolyte imbalances: Furosemide can lead to low potassium (hypokalemia), low sodium (hyponatremia), low calcium (hypocalcemia), and low magnesium (hypomagnesemia).

Low blood pressure (hypotension): Especially when starting the medication or increasing the dose.

Kidney damage: Prolonged use or high doses can affect kidney function, especially in patients with existing kidney disease.

Ototoxicity: High doses or rapid intravenous administration can lead to hearing damage, particularly in patients with pre-existing kidney problems.

Gout: Furosemide can increase the levels of uric acid in the blood, which might trigger gout attacks.

Rashes or allergic reactions: Some patients may develop skin reactions or more severe allergic responses.

Precautions

Electrolyte monitoring: Patients on furosemide should have regular blood tests to monitor their electrolyte levels, especially potassium and sodium.

Kidney function: Kidney function should be closely monitored, as furosemide can potentially cause kidney damage, especially at higher doses or with pre-existing kidney disease.

 

Pregnancy and breastfeeding: Furosemide is classified as a category C drug in pregnancy, meaning it should only be used if clearly needed. It passes into breast milk, so a doctor should be consulted if breastfeeding.

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• Delivery Time: PROMPT
• Packaging Details: 25KG DRUM PACK

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We are offering high quality of Mebeverine Hcl We are known for manufacturing, exporting, distributing, trading and supplying Mebeverine Hcl in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Mebeverine Hcl in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Mebeverine Hcl .Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Mebeverine Hcl as well as Intermediates of Mebeverine Hcl  Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Mebeverine Hcl to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Mebeverine Hydrochloride (HCl) – Description and Details

What is Mebeverine HCl?

Mebeverine Hydrochloride (HCl) is an antispasmodic medication used to treat symptoms of irritable bowel syndrome (IBS) and other functional bowel disorders. It works by relaxing the smooth muscles of the gut, reducing spasms, and relieving pain and discomfort.

Mechanism of Action

Mebeverine acts directly on the smooth muscle of the gastrointestinal (GI) tract. Unlike other antispasmodics, it does not affect normal gut motility or cause excessive relaxation. It works by:

Blocking calcium channels in the intestinal smooth muscle

Inhibiting sodium and potassium movement, preventing excessive contractions

Reducing painful spasms without altering normal bowel function

Indications (Uses)

Mebeverine HCl is commonly prescribed for:
 Irritable Bowel Syndrome (IBS) (abdominal pain, bloating, diarrhea, and constipation)
 Chronic irritable colon conditions
 Spastic colitis
 Other gastrointestinal disorders involving spasms

Dosage and Administration

Typically available as 135 mg tablets or 200 mg extended-release capsules

Usual adult dose: 135 mg three times a day before meals

Extended-release capsules: 200 mg twice daily

Should be taken before food, swallowed whole with water

Not recommended for children under 18 years unless prescribed by a doctor

Side Effects

Mebeverine is generally well tolerated, but possible side effects include:

Mild gastrointestinal discomfort (nausea, constipation, diarrhea)

Dizziness or headaches (rare)

Allergic reactions (rash, itching, swelling – seek medical help if severe)

 

Product Details:

We are offering high quality of Isoflupredone Acetale powder. We are known for manufacturing, exporting, distributing, trading and supplying Isoflupredone Acetale powder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Isoflupredone Acetale powder in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

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Isoxsuprine HCL (Isoxsuprine Hydrochloride) is a medication primarily used as a vasodilator and smooth muscle relaxant. It is commonly prescribed for conditions such as peripheral vascular diseases, to improve blood flow, and for certain types of muscle spasms.

Technical Details:

Chemical Name:
1-(4-Hydroxyphenyl)-3-(isopropylamino)-2-propanol hydrochloride.

Molecular Formula:
C18H24ClNO2.

Molecular Weight:
315.85 g/mol.

CAS Number:
83-10-1.

Structure:
Isoxsuprine has a structure that includes a phenyl group (aromatic ring) with a hydroxyl group (-OH) at the para position and a isopropylamino group (-N-CH(CH3)2) attached to the propanol side chain.

Solubility:

Soluble in water, methanol, and ethanol.

Slightly soluble in chloroform.

Side Effects:

Common side effects may include nausea, dizziness, and flushing.

In rare cases, it can cause palpitations, headache, and hypotension (low blood pressure).

Dosage and Administration:
The typical dosage varies based on the specific condition being treated and patient response. Commonly, the drug is administered orally in tablet form.

Adults: The usual dose is 10-20 mg, taken 3-4 times a day.

Pediatric Use: Dosage in children is based on body weight and is typically lower than the adult dose.

Contraindications:

Not to be used in patients with hypersensitivity to isoxsuprine or other ingredients in the formulation.

Caution is advised in patients with heart conditions like arrhythmias, as isoxsuprine may exacerbate certain heart issues.

Drug Interactions:

Isoxsuprine may interact with other medications that affect blood pressure or heart function.

It is essential to monitor for interactions with other vasodilators or beta-adrenergic blockers.

7. Precautions

Caution is needed in patients with a history of heart disease, hypertension, or liver or kidney problems.

Pregnancy and breastfeeding: It should only be used during pregnancy when absolutely necessary and under the guidance of a healthcare provider.

 

 8. Clinical Applications

Raynaud's disease: Isoxsuprine helps in treating vasospastic disorders (where blood vessels constrict too much), improving the flow of blood to extremities.

Peripheral arterial diseases: Helps increase circulation, especially in conditions like arteriosclerosis or diabetic neuropathy.

 

Additional Information:

• Delivery Time: prompt
• Packaging Details: drum or bag

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We are offering high quality of Ketorolac Tromethamine Powder . We are known for manufacturing, exporting, distributing, trading and supplying Ketorolac Tromethamine Powder   in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

 

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Ketorolac Tromethamine Powder   in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Ketorolac Tromethamine Powder . Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Ketorolac Tromethamine Powder  as well as Intermediates of Ketorolac Tromethamine Powder .  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Ketorolac Tromethamine is a nonsteroidal anti-inflammatory drug (NSAID) used for its potent analgesic (pain-relieving) effects. It is primarily indicated for the short-term management of moderate to severe pain, often after surgery or for conditions requiring strong pain relief.

Description & Details

Chemical Name: (±)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol

Molecular Formula: C₁₅H₁₃NO₃·C₄H₁₁NO₃

Molecular Weight: 376.40 g/mol

Uses & Indications

Short-term treatment of moderate to severe pain (e.g., post-surgical pain)

Alternative to opioids for pain management

Used in both oral and injectable forms

Ophthalmic form used for eye pain and inflammation

Pharmacokinetics

Absorption: Rapidly absorbed when given orally or intramuscularly.

Onset of Action: 30-60 minutes after administration.

Peak Plasma Concentration: 1-3 hours.

Half-Life: 4-6 hours in adults; prolonged in elderly patients and those with renal impairment.

Excretion: Primarily through the kidneys (urine).

Available Forms & Strengths

Oral Tablets: 10 mg

Injection (IV/IM): 15 mg/mL, 30 mg/mL

Ophthalmic Solution: 0.5% (for eye pain and inflammation)

Indications

Postoperative pain

Musculoskeletal pain

Renal colic

Pain management in emergency settings

Contraindications

History of gastrointestinal bleeding or ulcers

Severe kidney impairment

Active bleeding disorders

Hypersensitivity to NSAIDs

Pregnancy (especially in the third trimester)

Side Effects

Common: Nausea, dizziness, headache, stomach pain

Serious: Gastrointestinal bleeding, kidney damage, cardiovascular risks (heart attack, stroke)

Precautions & Warnings

Not for long-term use (should not exceed 5 days of treatment).

Avoid in elderly patients with kidney issues.

Use caution in asthma patients, as NSAIDs can trigger bronchospasms.

Should not be combined with other NSAIDs to avoid toxicity.

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• Delivery Time: IMMEDIATELY
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We are offering high quality of DUTASTERIDE API POWDER . We are known for manufacturing, exporting, distributing, trading and supplying DUTASTERIDE API POWDER   in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier DUTASTERIDE API POWDER   in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of DUTASTERIDE API POWDER . Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing DUTASTERIDE API POWDER  as well as Intermediates of DUTASTERIDE API POWDER .  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export DUTASTERIDE API POWDER  to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Dutasteride API Powder is the active pharmaceutical ingredient (API) for the drug Dutasteride, which is primarily used in the treatment of benign prostatic hyperplasia (BPH) and androgenetic alopecia (male pattern baldness). Dutasteride works by inhibiting the enzyme 5-alpha-reductase, which plays a key role in the conversion of testosterone to dihydrotestosterone (DHT), a hormone responsible for prostate growth and hair loss in men.
Description:
Chemical Name: (5α, 17β)-N-{2,5-bis(trifluoromethyl)phenyl}-
3-oxo-4-aza-5α-androst-1-en-17-yl}-2,2,2-trifluoroacetamide
Molecular Formula: C27H30F6N2O2
CAS Number: 164656-23-9
Appearance: Dutasteride API Powder is typically a white to off-white crystalline powder with no distinct odor. The substance is practically insoluble in water but can dissolve in organic solvents such as ethanol.
Side Effects:
While Dutasteride is generally well tolerated, there are potential side effects, including:
Sexual Dysfunction: The most common side effects related to Dutasteride include decreased libido, erectile dysfunction, and ejaculation disorders. These side effects may persist even after discontinuation of the drug in some cases.
Breast Changes: Some men may experience breast tenderness, enlargement, or lumps, which may indicate gynecomastia.
Allergic Reactions: Rash, swelling, and itching may occur.
Liver Enzyme Elevation: Some individuals may experience an increase in liver enzymes; liver function should be monitored during treatment.
Cautions:Liver Impairment: Caution is required in individuals with liver dysfunction, as Dutasteride is metabolized in the liver. Dose adjustment or monitoring may be necessary.
Prostate Cancer: Dutasteride can mask symptoms of prostate cancer, as it reduces PSA (prostate-specific antigen) levels. It should not be used as a diagnostic test for prostate cancer.
Breast Tissue Changes: Any changes in the breast, such as lumps or tenderness, should be reported, as it may indicate gynecomastia.
Storage:Storage Conditions: Dutasteride API Powder should be stored in a cool, dry place, away from moisture and light. It should be kept in an airtight container to prevent degradation and contamination.
Purity: Dutasteride API Powder should have a purity of at least 99% to ensure its effectiveness and safety when formulated into final dosage forms. It is critical that the powder undergoes quality control testing, such as HPLC to verify its purity and ensure that it meets pharmacopeial standards.

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• Item Code: 995412
• Delivery Time: Prompt
• Packaging Details: Drum

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We are offering high quality of  Famotidine
We are known for manufacturing,exporting, distributing, trading and supplying Famotidine Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Famotidine in Gujarat. India. Shreeji Pharma International manufacturing & suppling all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Famotidine Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Famotidine as well as Intermediates of  Famotidine.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Famotidine to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries.
Famotidine API Powder is the active pharmaceutical ingredient (API) used in the formulation of drugs that reduce stomach acid production. Famotidine is a histamine H2-receptor antagonist (H2 blocker) and is commonly used to treat conditions related to excess stomach acid, such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.
Here’s a detailed description of Famotidine API Powder:
Chemical Name:
Famotidine.
Molecular Formula:
C8H15F3N6S.
Molecular Weight:
337.31 g/mol.
CAS Number:
11004-37-4.
Chemical Structure:
Famotidine consists of a imidazole ring, a thiazole ring, and a methyl group, with a trifluoromethyl group attached to the aromatic structure. Its molecular structure contributes to its ability to selectively block histamine receptors, which results in a decrease in gastric acid secretion.
Appearance:
Famotidine API is a white to off-white crystalline powder. It is odorless and is generally considered to be stable under normal storage conditions.

Side Effects:
Famotidine is generally well tolerated, but some side effects may include:
Common Side Effects:
Headache.
Dizziness.
Constipation or diarrhea.
Fatigue or weakness.
Less Common Side Effects:
Skin rash or itching
Elevated liver enzymes or hepatitis (in rare cases).
Serious Side Effects (rare):
Allergic reactions: Symptoms may include swelling of the face, lips, or throat, leading to difficulty breathing (anaphylaxis).
Severe skin reactions, such as Stevens-Johnson syndrome (rare).
Mental confusion, particularly in elderly patients or those with impaired kidney function.
Precautions:Renal Impairment: Famotidine is primarily excreted through the kidneys. Dose adjustments may be needed in patients with renal impairment to prevent accumulation of the drug and reduce the risk of side effects.
Pregnancy and Breastfeeding: Famotidine should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus. It is excreted into breast milk, so it should be used cautiously in breastfeeding mothers.
Gastric Cancer: Famotidine should not be used to self-treat gastric cancer, as it could mask symptoms of the disease. It is important to confirm the diagnosis with medical professionals before starting treatment.
Drug Interactions: Famotidine can interact with certain drugs, including: Storage:Famotidine powder should be stored in a cool, dry place, away from direct sunlight and moisture. The temperature should be below 25°C (77°F).
Keep the product tightly closed in its original container to protect it from moisture and contamination.

 

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We are offering high quality of Gabapentin Powder. We are known for manufacturing, exporting, distributing, trading and supplying Gabapentin Powder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Gabapentin Powder  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

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Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Gabapentin Powder as well as Intermediates of Gabapentin Powder.

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Shreeji Pharma International currently export Gabapentin Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Gabapentin is a medication primarily used to treat nerve pain and prevent seizures. It is often prescribed for conditions like neuropathic pain, postherpetic neuralgia, restless leg syndrome, and as an adjunctive treatment for partial seizures. Here are some of the key technical details:

1. Chemical Properties                     

IUPAC Name: 2-(1-Amino- cyclohexyl)acetic acid

Molecular Formula: C9H17NO2

Molecular Weight: 171.24 g/mol

Structure: Gabapentin is a structural analogue of the neurotransmitter gamma-aminobutyric acid (GABA), but it does not bind to GABA receptors. It has a cyclohexane ring attached to an acetic acid group.

Solubility: It is highly soluble in water and is typically available in oral formulations such as tablets, capsules, and oral solution.

3. Common Uses

Neuropathic Pain: Gabapentin is often prescribed for various types of nerve pain, such as:

Postherpetic Neuralgia: Pain following shingles infection.

Diabetic Neuropathy: Nerve damage caused by diabetes.

Seizures: It is used as an adjunctive therapy (meaning it's used in addition to other medications) to control partial seizures in epilepsy.

Restless Legs Syndrome (RLS): Gabapentin can help reduce symptoms like discomfort and the urge to move the legs, particularly at night.

Fibromyalgia: In some cases, gabapentin is prescribed for fibromyalgia, a condition that causes widespread pain and fatigue.

A typical starting dose for neuropathic pain might range from 300 mg per day, increasing gradually to a total of 900-3,600 mg per day, depending on how well the patient tolerates the medication.

5. Side Effects

Like any medication, gabapentin can cause side effects. Common ones include:

Drowsiness

Dizziness

Fatigue

Swelling (especially in the legs and ankles)

Coordination problems

Gastrointestinal issues (nausea, vomiting)

Serious but rare side effects may include:

Severe allergic reactions (e.g., swelling, rash, difficulty breathing)

6. Precautions and Interactions

Kidney Function: Gabapentin is primarily excreted by the kidneys, so patients with impaired kidney function need adjusted doses to avoid accumulation and potential toxicity.

 

 

 

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• Delivery Time: prompt
• Packaging Details: drum or bag

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We are offering high quality of Alendronate Sodium. We are known for manufacturing, exporting, distributing, trading and supplying Alendronate Sodium in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier

Alendronate Sodium in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Alendronate Sodium. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Alendronate Sodium as well as Intermediates of Alendronate Sodium.

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Shreeji Pharma International currently export Alendronate Sodium to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Chemical Name: Alendronate Sodium

Synonyms: Alendronic Acid Sodium Salt, Fosamax (brand name)

Molecular Formula: C₄H₁₂NNaO₇P₂

Molecular Weight: 271.08 g/mol

CAS Number: 121268-17-5 (monosodium salt), 66376-36-1 (trihydrate)

Appearance: White or off-white crystalline powder

Solubility: Soluble in water, slightly soluble in alcohol

pH (Solution): 4.0 - 5.0 (for aqueous solution)

Uses & Applications:

Alendronate Sodium is a bisphosphonate medication primarily used to prevent and treat osteoporosis in postmenopausal women and individuals at risk of bone loss.

It works by inhibiting osteoclast-mediated bone resorption, thereby increasing bone mass and reducing fracture risk.

Also used for Paget’s disease of bone and other conditions related to abnormal bone turnover.

Pharmacological Properties:

Bioavailability: Low (around 0.6-0.7%) when taken orally.

Half-Life: Long, as it incorporates into bone and may persist for years.

Excretion: Mostly excreted unchanged via the kidneys.

Pharmaceutical Use:Alendronate sodium is widely used in the treatment and prevention of osteoporosis in postmenopausal women.

It is prescribed to increase bone mass in men with osteoporosis.

Used in managing bone loss due to long-term corticosteroid therapy.Also indicated for treating Paget’s disease of bone.

Mode of Action:It is a bisphosphonate, which works by inhibiting osteoclast-mediated bone resorption, thereby increasing bone mineral density.

Administration: Taken orally with a full glass of water on an empty stomach.

Patients should remain upright for at least 30 minutes after taking to avoid esophageal irritation.

Storage Conditions:Store in a cool, dry place at room temperature (15°C–30°C / 59°F–86°F).

Protect from moisture and direct sunlight.

Handling Precautions:Use gloves and a mask when handling in powder form to avoid inhalation.

Avoid contact with eyes and prolonged skin exposure.

Side Effects:Common: Acid reflux, nausea, abdominal pain, and muscle pain.

Serious: Esophageal ulcers, jaw osteonecrosis (rare but severe condition), and atypical femur fractures with long-term use.

Contraindications:Patients with esophageal abnormalities, severe kidney impairment, or hypocalcemia should avoid use.

Not recommended for individuals who cannot remain upright for 30 minutes after administration.

Drug Interactions:Avoid taking with calcium, magnesium, iron, or antacids within 30 minutes as they reduce absorption.

Additional Information:

• Delivery Time: immediate
• Packaging Details: HDPE DRUM PACK

Product Details:

We are offering high quality of Magnesium Lactate Powder. We are known for manufacturing, exporting, distributing, trading and supplying Magnesium Lactate Powder  in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Magnesium Lactate Powder  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Magnesium Lactate Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Magnesium Lactate Powder as well as Intermediates of Magnesium Lactate Powder.   

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Magnesium Lactate Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Overview:
Magnesium Lactate is a high-quality, bioavailable form of magnesium that is easily absorbed by the body. It is a salt of magnesium and lactic acid, commonly used as a dietary supplement to support overall health.

Magnesium Lactate Powder - Detailed Description

Overview:

Magnesium lactate is a magnesium salt of lactic acid, widely used as a dietary supplement to support magnesium levels in the body. It is known for its high bioavailability and gentle effect on the digestive system, making it a preferred form of magnesium supplementation.

Chemical Information:

Chemical Name: Magnesium lactate

Molecular Formula: C6H10MgO6

Molecular Weight: 202.45 g/mol

CAS Number: 18917-93-6

Solubility: Soluble in water

Appearance: White crystalline or powder form

Key Benefits & Uses:

Magnesium Supplementation:

Helps maintain normal muscle and nerve function.

Supports cardiovascular health.

Aids in energy production and metabolism.

Essential for bone health and proper calcium absorption.

Food Additive & Fortification:

Used as a food additive in health products.

Enhances nutritional value in functional foods and beverages.

Pharmaceutical Applications:

Used in medications for magnesium deficiency treatment.

Aids in managing conditions such as muscle cramps, fatigue, and migraines.

Sports & Fitness:

Helps prevent muscle cramps and supports athletic performance.

Contributes to post-exercise recovery.

Advantages of Magnesium Lactate Powder:

Highly Absorbable: Superior bioavailability compared to other magnesium forms.

Gentle on Stomach: Less likely to cause digestive discomfort.

Versatile Use: Can be used in dietary supplements, functional foods, and pharmaceutical formulations.

Non-GMO & Safe: Typically free from additives and preservatives.

Recommended Dosage:

Dietary Supplement: Typically 200-400 mg per day (as per healthcare professional’s advice).

Food Fortification: As per industry standards and regulatory guidelines.

Storage & Shelf Life:

Storage: Keep in a cool, dry place, away from direct sunlight and moisture.

Shelf Life: Generally 2-3 years when stored properly.

 

Additional Information:

• Delivery Time: immediate
• Packaging Details: Drum pack

Product Details:

We are offering high quality of Magnesium Trisilicate Powder. We are known for manufacturing, exporting, distributing, trading and supplying Magnesium Trisilicate Powder  in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Magnesium Trisilicate Powder  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Magnesium Trisilicate Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Magnesium Trisilicate Powder as well as Intermediates of Magnesium Trisilicate Powder.   

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Magnesium Trisilicate Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Magnesium Trisilicate Powder – Detailed Description

Chemical Information:

Chemical Formula: Mg₂Si₃O₈·xH₂O

Molecular Weight: Variable (depends on hydration level)

CAS Number: 14987-04-3

Physical Properties:

Appearance: White or off-white, fine, odorless powder

Solubility: Practically insoluble in water and alcohol

pH (suspension in water): Slightly alkaline

Uses & Applications:

Magnesium Trisilicate Powder is primarily used as an antacid and adsorbent in pharmaceuticals. It neutralizes stomach acid and provides relief from indigestion, acid reflux, and peptic ulcers. Other applications include:

Pharmaceuticals: Commonly used in antacid formulations.

Food Industry: As an anti-caking agent in food products.

Cosmetics & Personal Care: Used as an absorbent in skincare products.

Industrial Uses: As a filler material in rubber, paints, and coatings.

Pharmacological Action:

Reacts with gastric acid to form magnesium chloride and silicic acid, which coats the stomach lining and provides a protective effect.

Works slower than other antacids but provides long-lasting relief.

Minimal systemic absorption, making it safe for long-term use in controlled doses.

Dosage & Administration:

Oral Use: Commonly administered in suspension or tablet form.

Typical Dosage: 500 mg to 1 g per dose, taken 3-4 times daily (as per medical guidance).

Safety & Precautions:

Side Effects: May cause diarrhea (due to magnesium content) or constipation when combined with other antacids.

Contraindications: Should not be used in patients with kidney disease or severe dehydration.

Interactions: May affect the absorption of other medications like tetracyclines and fluoroquinolones.

Storage & Stability:

Store in a cool, dry place, away from moisture.

Keep in a sealed container to prevent contamination.

Stable under normal storage conditions but should be protected from excessive heat.

 Chemical Formula: Mg₂Si₃O₈·xH₂O

Appearance: White, fine, odorless powder

Solubility: Practically insoluble in water and ethanol

 

 

Additional Information:

• Production Capacity: 25000
• Delivery Time: immediate
• Packaging Details: HDPE DRUM

Product Details:

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Cetirizine dihydrochloride in Gujarat, India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Cetirizine dihydrochloride. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Cetirizine dihydrochloride as well as Intermediates of Cetirizine dihydrochloride.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Cetirizine dihydrochloride to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Cetirizine Dihydrochloride (often abbreviated as Cetirizine HCl) is an antihistamine commonly used to treat symptoms associated with allergies, such as runny nose, sneezing, itchy or watery eyes, and itching of the throat or nose. It is also effective in treating symptoms of hay fever, seasonal allergic rhinitis, and other allergic conditions like urticaria (hives). Cetirizine is a second-generation antihistamine, which means it tends to cause less drowsiness compared to first-generation antihistamines.
Chemical Properties:
Chemical Name: Cetirizine dihydrochloride
Molecular Formula: C21H25ClN2O3
CAS Number: 83881-51-0
Class: Antihistamine (H1 receptor antagonist)
Form: White to off-white crystalline powder that is soluble in water.
Mechanism of Action:
Cetirizine works by selectively blocking the H1 histamine receptor, which is involved in allergic reactions. When histamine is released by the body during an allergic response, it binds to these receptors, causing the typical symptoms like swelling, redness, and itching. By blocking these receptors, cetirizine reduces the effects of histamine, leading to relief from symptoms like itching, sneezing, and watery eyes.
Indications:
Allergic Rhinitis: Seasonal or perennial allergic rhinitis (e.g., hay fever).
Urticaria: Chronic idiopathic urticaria (hives).Other Allergic Conditions: Includes symptoms of pollen, dust, or pet allergies.
Dosage Forms:
Cetirizine is available in various forms, including:
Tablets: Typically in 5 mg or 10 mg doses.
Syrup: Usually 1 mg/mL
Chewable Tablets: Available for children.
Typical Dosage:
Adults and Children over 6 years: 10 mg once daily.
Children 2-6 years: 5 mg once daily.
Children under 2 years: Dosage is typically based on weight and should be guided by a healthcare provider.
Side Effects:
While cetirizine is considered less sedating than older antihistamines, it can still cause side effects in some people, including:
Drowsiness (though much less common than first-generation antihistamines)
Dry mouth
Headache
Dizziness
Nausea
Fatigue
Precautions and Warnings:
Alcohol Use: Avoid alcohol, as it may increase the sedative effects of cetirizine.
Renal Impairment: Dosage adjustments may be necessary in patients with kidney problems.
Pregnancy and Breastfeeding: It is considered relatively safe during pregnancy, but should be used only if needed. It is also excreted in breast milk, so consult a healthcare provider if you are breastfeeding.
Children: The drug is generally safe for children over 2 years, but younger children should only take cetirizine under the guidance of a healthcare provider.
Drug Interactions:
Cetirizine may interact with certain medications, such as:
Central Nervous System Depressants: Including alcohol, sedatives, or tranquilizers.

Additional Information:

• Production Capacity: 2000
• Delivery Time: prompt

Product Details:

We are offering high quality of Desloratadine We are known for manufacturing,exporting, distributing, trading and supplying Desloratadine in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Desloratadine in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Desloratadine Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Desloratadine as well as Intermediates of Desloratadine Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Desloratadine to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries
 Desloratadine is a second-generation antihistamine commonly used to treat allergic reactions, including rhinitis (hay fever) and urticaria (hives). It is the active pharmaceutical ingredient (API) in various over-the-counter medications for allergic conditions. Desloratadine is a metabolite of loratadine, and it is known for its non-sedating properties, making it suitable for daytime use.
1. Chemical Description:Chemical Name: (E)-3-[(2-{4-(Dibenzhydryloxy)-3-pyridyl}phenyl)-methyl]-2-propenylamineMolecular Formula: C19H19ClN2
Molecular Weight: 310.83 g/mol
CAS Number: 100643-71-8
Desloratadine is a chlorinated compound with a pyridine ring in its structure and exhibits selective antagonism to peripheral histamine H1 receptors.
3. Uses:
Desloratadine is primarily used to treat conditions related to allergies, such as:
Allergic Rhinitis: Seasonal or perennial hay fever, causing symptoms like sneezing, nasal congestion, and runny nose.
Chronic Urticaria (Hives): A skin condition characterized by red, itchy, raised welts or hives.
4. Physical Characteristics:
Appearance: Desloratadine API powder is typically a white to off-white crystalline powder.

Solubility: It is slightly soluble in water but soluble in ethanol and other organic solvents.
Stability: Desloratadine powder is relatively stable when stored in dry conditions. It should be kept in airtight containers to avoid moisture.
7. Side Effects:
Desloratadine is well-tolerated by most people, but it can cause some mild side effects. Common side effects may include:
Headache
Dry mouth
Fatigue
Sore throat

8. Precautions:
Pregnancy and Lactation: Desloratadine is categorized as Pregnancy Category C, meaning its safety during pregnancy has not been fully established. It should be used only if the potential benefit justifies the risk. It is excreted in breast milk, so caution is advised for breastfeeding mothers.
Liver and Kidney Disease: Caution should be used in patients with severe liver or kidney impairment. Dosage adjustments may be necessary in such cases.
9. Storage:
Desloratadine API powder should be stored in a cool, dry place, typically at a temperature range of 15°C to 30°C (59°F to 86°F).
It should be stored in airtight containers to protect it from moisture and contamination.
The product should be kept away from direct sunlight and high humidity.

Additional Information:

• Delivery Time: PROMPT
• Packaging Details: 25KG DRUM PACK

Product Details:

We are offering high quality Biperiden HCL.We are known for manufacturing, exporting, distributing, trading and supplying Biperiden HCL in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Biperiden HCL in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Biperiden HCL Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing  Biperiden HCL as well as Intermediates of Biperiden HCL.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Bethanechol Chloride to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Biperiden Hydrochloride (HCl) Powder is a medication primarily used as an anticholinergic agent to treat symptoms of Parkinson's disease and drug-induced extrapyramidal disorders (such as those caused by antipsychotic drugs). It works by blocking the effects of acetylcholine, a neurotransmitter involved in controlling muscle movements, thereby helping reduce muscle stiffness, tremors, and other symptoms associated with movement disorders.

Biperiden Hydrochloride (HCl) Powder - Description and Detail
Active Ingredient:
Name: Biperiden Hydrochloride (HCl)
Molecular Formula: C21H29NO·HCl
Molecular Weight: 343.93 g/mol
Physical Characteristics:
Appearance: White to off-white crystalline powder.
Solubility: Soluble in water and alcohol.
Odor: Typically odorless or slightly odorless.
Pharmaceutical Formulation:
Form: Powder for oral or injectable use (depending on formulation).
Concentration: Often provided in concentrations that can be reconstituted to form an injectable solution or used as part of a tablet formulation (typically 2–5 mg per dose).
Excipients: Depending on the preparation, the powder might contain excipients for stability or ease of reconstitution (such as sodium chloride for injections or fillers for oral preparations).

Mechanism of Action:Biperiden is an anticholinergic agent that selectively blocks muscarinic receptors in the brain, which helps in balancing the neurotransmitter activity.
In Parkinson’s disease, the dopaminergic system is compromised, leading to an imbalance with acetylcholine, which causes symptoms like tremors and rigidity. By blocking acetylcholine’s effects, Biperiden helps alleviate these symptoms.
It is also used to treat extrapyramidal symptoms caused by antipsychotic medications, which can lead to tremors, rigidity, and involuntary movements.

Indications:Parkinson's Disease: Used as an adjunct therapy to help reduce tremors, muscle rigidity, and other symptoms associated with Parkinson’s disease.

Extrapyramidal Side Effects: Often prescribed for drug-induced movement disorders, such as those caused by antipsychotic medications (e.g., tardive dyskinesia).

Other Neurological Disorders: May be used off-label for various movement disorders where an imbalance between dopamine and acetylcholine is suspected.

Additional Information:

• Delivery Time: immediate
• Packaging Details: HDPE DRUM PACK

Product Details:

We are offering high quality of Atenolol .We are known for manufacturing, exporting, distributing, trading and supplying Atenolol in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Atenolol in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory support..

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Isoxsuprine HCL owadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Isoxsuprine HCL as well as Intermediates of Isoxsuprine HCL.Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Isoxsuprine HCL to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Technical specifications:

Chemical name: Atenolol

CAS Number: 29122-68-7

Synonyms: 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxyl]benzeneacetamide; 2-[p-[2-Hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide;(RS)-Atenolol; (+/-)-Atenolol; Atehexal; Atenol; Cuxanorm; Myocord; Normalol; Normiten; Uniloc; Vericordin; Wesipin; Xaten; dl-Atenolol (USP);

Molecular form: C14H22N2O3

Appearance: White Solid

Mol. Weight: 266.34

Storage: 2-8°C Refrigerator

Introduction:Atenolol is a cardio-selective beta-blocker and as such exerts most of its effects on the heart.Label It acts as an antagonist to sympathetic innervation and prevents increases in heart rate, electrical conductivity, and contractility in the heart due to increased release of norepinephrine from the peripheral nervous system.Label,24,14 Together the decreases in contractility and rate produce a reduction in cardiac output resulting in a compensatory increase in peripheral vascular resistance in the short-term. This response later declines to baseline with long-term use of atenolol. More importantly, this reduction in the work demanded of the myocardium also reduces oxygen demand which provides therapeutic benefit by reducing the mismatch of oxygen supply and demand in settings where coronary blood flow is limited, such as in coronary atherosclerosis. Reducing oxygen demand, particularly due to exercise, can reduce the frequency of angina pectoris symptoms and potentially improve survival of the remaining myocardium after myocardial infarction. The decrease in rate of sinoatrial node potentials, electrical conduction, slowing of potentials traveling through the atrioventricular node, and reduced frequency of ectopic potentials due to blockade of adrenergic beta receptors has led to benefit in arrhythmic conditions such as atrial fibrillation by controlling the rate of action potential generation and allowing for more effective coordinated contractions.

Atenolol is used to:

decrease hypertension (high blood pressure) reduce angina (chest pain) after a heart attack, reduce the amount of work your heart muscle has to do to push blood through your body

Atenolol may cause side effects. 

dizziness,lightheadedness

tiredness,drowsiness

depression,nausea, diarrhea

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:shortness of breathswelling of the hands, feet, ankles, or lower legs,unusual weight gain,fainting.

Additional Information:

• Delivery Time: immediate
• Packaging Details: HDPE DRUM PACK

Product Details:

We are offering high quality of Clopidogrel bisulphate. We are known for manufacturing, exporting, distributing, trading and supplying Clopidogrel bisulphate in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Clopidogrel bisulphate in Gujarat, India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Clopidogrel bisulphate. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Clopidogrel bisulphate as well as Intermediates of Clopidogrel bisulphate.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Clopidogrel bisulphate to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Clopidogrel Bisulfate is the salt form of clopidogrel, a medication used primarily to prevent blood clots in patients at risk for cardiovascular events. Here is a detailed description of clopidogrel bisulfate:
Chemical Information:
IUPAC Name: 2-CHLORO-6-(OCH3)PYRIDIN-3-YL-(2S)-2-(O-THIOPHOSPHORYL)THIOMETHYL-1-THIAZOLE-4(3H)-ONE BISULFATE
Molecular Formula: C16H16ClNO2S2·H2SO4
Molecular Weight: 419.85 g/mol
Mechanism of Action:
Clopidogrel is an antiplatelet medication, meaning it works by preventing platelets in the blood from clumping together, thus reducing the formation of blood clots. It is an ADP receptor antagonist. Specifically, clopidogrel inhibits the P2Y12 receptor on platelets, which prevents the activation of GPIIb/IIIa receptors, which are crucial for platelet aggregation.
Indications:
Clopidogrel is used for:
Acute Coronary Syndrome (ACS): In conditions like unstable angina and myocardial infarction (heart attack), clopidogrel is used in conjunction with other treatments to prevent clot formation.
Preventing Stroke: For patients who have had a previous ischemic stroke or other vascular events, it helps prevent further strokes by reducing blood clots.
Peripheral Arterial Disease (PAD): Helps prevent clots in individuals with PAD, a condition where the blood vessels in the limbs are narrowed.
Coronary Artery Disease (CAD): Prevents clot formation in people with CAD, especially after procedures like stent placement.
Dosage and Administration:
Clopidogrel bisulfate is typically administered orally in tablet form.
Standard Dosage: The usual dosage is 75 mg once daily for most indications.
Acute Coronary Syndrome: A loading dose of 300 mg or 600 mg may be given, followed by 75 mg daily.
Side Effects:
While generally well-tolerated, common side effects can include:
Bleeding: The most serious side effect due to its antiplatelet effect, leading to easy bruising, nosebleeds, or more severe hemorrhage.
Gastrointestinal Issues: Diarrhea, nausea, and abdominal pain.
Rash: Skin reactions in some patients.
Headache: A potential side effect in some individuals.
Contraindications:
Active Bleeding Disorders: Patients with a history of bleedingdisorders (e.g., peptic ulcer disease or intracranial hemorrhage) should avoid clopidogrel.
Hypersensitivity to Clopidogrel: If the patient has an allergy to the drug or any of its components.

Additional Information:

• Production Capacity: 1000
• Delivery Time: prompt

Product Details:

We are offering high quality of Lansoprazole Api Powder. We are known for manufacturing, exporting, distributing, trading and supplying Lansoprazole Api Powder  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Lansoprazole Api Powder  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

 Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Lansoprazole Api Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Lansoprazole Api Powder as well as Intermediates of Lansoprazole Api Powder.  Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Lansoprazole Api Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Lansoprazole is a proton pump inhibitor (PPI) used to reduce stomach acid production. It is commonly prescribed for conditions such as:

Indications & Uses:

Gastroesophageal reflux disease (GERD) – Treats acid reflux and heartburn.

Peptic ulcers – Helps heal stomach and duodenal ulcers.

Zollinger-Ellison syndrome – Manages excessive acid production.

Helicobacter pylori infection – Used with antibiotics to eradicate H. pylori.

Erosive esophagitis – Helps heal acid damage to the esophagus.

Mechanism of Action:

Lansoprazole inhibits the H+/K+ ATPase enzyme in gastric parietal cells, blocking acid secretion in the stomach. This effect helps in relieving symptoms and promoting healing of acid-related conditions.

Dosage & Administration:

Typically taken once daily before meals.

Available in capsules or orally disintegrating tablets (ODT).

Dosage varies based on condition (e.g., 15-30 mg per day for GERD).

Side Effects:

Common:

Headache

Nausea

Diarrhea

Abdominal pain

Constipation

Serious (Rare):

Vitamin B12 deficiency (long-term use)

Osteoporosis-related fractures

Kidney issues

Clostridium difficile infection

Precautions:

Long-term use may lead to nutrient deficiencies (e.g., calcium, magnesium).

Can interact with warfarin, methotrexate, clopidogrel, and some antifungal drugs.

Avoid alcohol and smoking, as they can worsen acid-related conditions.

 General Information:Lansoprazole is a proton pump inhibitor (PPI) that reduces stomach acid production. It is commonly used to treat conditions related to excessive stomach acid, such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.

 

 

Indications:

Lansoprazole is prescribed for:

Gastroesophageal reflux disease (GERD)

Peptic ulcers (gastric and duodenal)

Erosive esophagitis

Zollinger-Ellison syndrome (a condition where excessive acid is produced)

Helicobacter pylori infection (as part of combination therapy for eradication)

Nonsteroidal anti-inflammatory drug (NSAID)-induced ulcers (treatment and prevention)

 Forms Available:
Capsules

Orally disintegrating tablets

Oral suspension

Additional Information:

• Delivery Time: 1 week
• Packaging Details: drum

Product Details:

We are offering high quality of Albuterol Sulphate. We are known for manufacturing, exporting, distributing, trading and supplying Albuterol Sulphate in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier

Albuterol Sulphate in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Albuterol Sulphate. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Albendazole as well as Intermediates of Albuterol Sulphate.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Albuterol Sulphate to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Chemical Information

Chemical Name: Albuterol sulfate

IUPAC Name: (RS)-4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol sulfate

Molecular Formula: (C₁₃H₂₁NO₃)₂•H₂SO₄

Molecular Weight: 576.71 g/mol (for sulfate salt)

CAS Number: 51022-70-9 (Albuterol sulfate)

Synonyms: Salbutamol sulfate, Ventolin sulfate

Physical & Chemical Properties

Appearance: White to off-white crystalline powder

Solubility: Soluble in water, slightly soluble in ethanol, insoluble in chloroform

Melting Point: Approximately 150°C (decomposes)

pH (1% Solution): 3.0 - 5.0

Stability: Stable under normal storage conditions, sensitive to light and moisture

Purity & Quality Parameters

Assay (HPLC): ≥ 98.0%

Water Content (KF): ≤ 1.0%

Residue on Ignition: ≤ 0.2%

Heavy Metals: ≤ 10 ppm

Impurities: Complies with USP/BP/EP standards

Pharmacological Properties

Mechanism of Action: Beta-2 adrenergic receptor agonist, relaxes bronchial smooth muscles

Therapeutic Use: Treatment of bronchospasm in asthma and COPD

Dosage Forms: Inhalers, nebulizer solutions, tablets, and injectable formulations

Indications & Uses:Treatment and prevention of bronchospasm in patients with reversible obstructive airway disease (e.g., asthma, COPD).

Exercise-induced bronchospasm prevention.

Used in nebulizers (after dilution) or in dry powder inhalers (DPI).

Dosage & Administration:Oral Inhalation (DPI or Nebulizer Solution):

Adults & Children (4+ years): 2.5 mg via nebulizer every 4–6 hours.

Inhaler (MDI/DPI): 90 mcg per actuation, typically 2 puffs every 4–6 hours as needed.

Oral Tablets (Less Commonly Used): 2-4 mg every 6-8 hours (Extended Release: 4-8 mg every 12 hours).

Intravenous (IV) (Hospital Use): Dosage varies based on severity.

Side Effects:Common: Tremors, nervousness, headache, palpitations, muscle cramps.

Serious: Paradoxical bronchospasm, tachycardia, hypokalemia, hyperglycemia.

Precautions & Warnings:

Use cautiously in patients with heart disease, hypertension, diabetes, hyperthyroidism.

Overuse may lead to decreased efficacy and increased risk of severe asthma attacks.

Avoid in patients with known hypersensitivity to albuterol or other sympathomimetic drugs.

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We are offering high quality of Benzyl Alcohol.We are known for manufacturing, exporting, distributing, trading and supplying Benzyl Alcohol in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Benzyl Alcohol in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
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Shreeji Pharma International currently export Benzyl Alcohol  to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
Benzyl Alcohol (C₆H₅CH₂OH) is an organic compound and aromatic alcohol, often used in various industries due to its versatile properties. Here's a detailed description of Benzyl Alcohol liquid:
Chemical Name: Benzyl Alcohol
Synonyms: Benzenemethanol, Phenylcarbinol
Chemical Formula: C₆H₅CH₂OH
CAS Number: 100-51-6
Physical Properties:
Appearance: Colorless to pale yellow liquid with a faint, pleasant, aromatic odor.
Molecular Weight: 108.14 g/mol.
Density: 1.04 g/cm³ at 20°C.
Boiling Point: 205.3°C (401.5°F).
Melting Point: -15°C (5°F).
Flash Point: 93°C (199.4°F).
Vapor Pressure: 0.12 mmHg at 20°C.
Solubility: Slightly soluble in water (4.1 g/100 mL at 20°C); however, it is miscible in alcohol, ether, chloroform, and acetone.
pH (in water solution): 6–7, slightly acidic.
Chemical Properties:
Functional Group: Alcohol group (-OH) attached to a benzene ring.
Reactivity: Benzyl alcohol can undergo various reactions typical for alcohols, such as oxidation, esterification, and reduction. It can be oxidized to produce benzaldehyde or benzoin. It can also form esters when reacted with acids, and it can be reduced to produce benzyl chloride.
Stability: Benzyl alcohol is stable under normal conditions and is not highly reactive, making it safe for use in many formulations.
Uses and Applications:
Solvent: Due to its mildness and ability to dissolve a wide range of organic and inorganic compounds, Benzyl Alcohol is used as a solvent in many applications, including in the formulation of paints, coatings, adhesives, and inks.
Cosmetics and Personal Care: It is used in cosmetics, lotions, shampoos, and creams as a preservative and fragrance ingredient due to its antimicrobial properties. It is often used as a stabilizer in formulations.
Pharmaceuticals: Benzyl alcohol acts as a solvent in injectable drug formulations and topical treatments. It is also used in some intravenous and intramuscular drug preparations as a bacteriostatic agent (to prevent bacterial growth).
Antimicrobial Agent: Due to its ability to inhibit bacterial growth, it is used as a preservative in many pharmaceutical and cosmetic products, especially those with water-based formulations.
Fragrance and Flavoring: With its mild, pleasant scent, Benzyl Alcohol is used in the formulation of perfumes and food flavorings.
Intermediate in Organic Synthesis: It is used as an intermediate in the synthesis of various chemicals such as benzyl esters, benzaldehyde, and benzoic acid derivatives.

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We are offering high quality of Lidocaine Hydrochloride POWDER. We are known for manufacturing, exporting, distributing, trading and supplying Lidocaine Hydrochloride POWDER  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Lidocaine Hydrochloride POWDER in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Lidocaine Hydrochloride POWDER. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Lidocaine Hydrochloride POWDER as well as Intermediates of Lidocaine Hydrochloride POWDER.   Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Lidocaine Hydrochloride POWDER to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries. Lidocaine Hydrochloride POWDER (also known as Lidocaine Hydrochloride POWDER) is a medication primarily used to treat respiratory conditions such as asthma, chronic obstructive pulmonary disease (COPD), and broncho spasms. It belongs to the class of bronchodilators, which help relax the muscles in the airways and improve airflow to the lungs.

Lidocaine Hydrochloride Powder: Detailed Description

1. General Information

Chemical Name: Lidocaine Hydrochloride

Synonyms: Lignocaine Hydrochloride, Xylocaine Hydrochloride

CAS Number: 73-78-9

Molecular Formula: C₁₄H₂₂N₂O·HCl

Molecular Weight: 270.80 g/mol

Appearance: White crystalline powder

Solubility: Highly soluble in water and alcohol

2. Properties & Characteristics

pH (1% solution): 4.0 – 5.5

Melting Point: 74–79°C

Boiling Point: 350.8°C at 760 mmHg

Purity: ≥ 99% (pharmaceutical grade)

Storage Conditions: Store in a cool, dry place, away from light and moisture

3. Uses & Applications

Local Anesthetic: Used for numbing tissues in specific areas (e.g., dental procedures, minor surgeries).

Antiarrhythmic Agent: Treats irregular heartbeats (ventricular arrhythmias).

Topical Anesthetic: Found in gels, creams, and sprays for pain relief.

Veterinary Use: Used in animal surgeries and treatments.

Research & Industrial Use: Sometimes used in laboratory applications and pharmaceutical formulations.

4. Mechanism of Action

Lidocaine Hydrochloride blocks sodium ion channels in nerve membranes, preventing nerve impulse transmission and producing a numbing effect.

5. Safety & Precautions

Side Effects: Dizziness, numbness, allergic reactions, irregular heartbeat (in high doses).

Contraindications: Should not be used in patients with severe liver disease, heart block, or hypersensitivity to local anesthetics.

Handling Precautions: Use gloves and protective gear; avoid inhalation and direct contact with skin.

Uses and Applications

Medical Use:

Local anesthesia in minor surgical procedures

Pain relief for burns, wounds, and mouth ulcers

Antiarrhythmic agent for ventricular arrhythmias

 

 

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We are offering high quality of  Disulfiram We are known for manufacturing,exporting, distributing, trading and supplying Disulfiram Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Disulfiram in Gujarat. India. Shreeji Pharma International manufacturing & suppling all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Disulfiram Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Disulfiram as well as Intermediates of  Disulfiram.Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Disulfiram to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries
Disulfiram is a medication primarily used for the treatment of chronic alcoholism. It works by inhibiting the enzyme acetaldehyde dehydrogenase, which is involved in the breakdown of alcohol in the body. When alcohol is consumed by someone taking disulfiram, the buildup of acetaldehyde causes unpleasant effects, which discourage drinking.
Description:
Chemical Name: 1,1-Dimethylethylthio)-m-tolylmethanone
Molecular Formula: C10H20N2S4
CAS Number: 97-77-8
Appearance: Disulfiram is typically available as a white to off-white crystalline powder.
Uses:
Alcoholism Treatment: Disulfiram is primarily used as part of a comprehensive treatment plan for people recovering from alcoholism. It acts as a deterrent to alcohol consumption.
Support for Alcohol Abstinence: The drug is typically prescribed alongside therapy, counseling, and support programs to aid in alcohol abstinence.
Used in Relapse Prevention: It is often used as a relapse prevention method, helping individuals maintain sobriety once they have stopped drinking alcohol.
Dosage and Administration:
Oral Administration: Disulfiram is generally taken orally in tablet or powder form. The dosage for adults typically starts at 250 mg to 500 mg daily, taken as a single dose. Over time, the dosage may be adjusted based on the individual’s response and tolerance.
Maintenance Dose: Once an initial response is achieved, the maintenance dose may be 125 mg to 500 mg daily, depending on the patient's needs.
In some cases, it can be provided as a powder to be compounded into a specific dosage or formulation. This may be used in clinical settings or customized prescriptions.
Side Effects:
Common side effects of Disulfiram include:
Drowsiness , Fatigue , Headache , Skin rash , Garlic-like odor on the breath
Serious side effects may include:
Hepatotoxicity: Liver damage, which is rare but can be severe. Regular liver function tests are recommended.
Psychiatric symptoms: Rare instances of depression, confusion, and psychosis have been reported.
Severe reaction to alcohol: Consuming alcohol while taking disulfiram can lead to severe reactions, including:
Flushing ,Nausea and vomiting ,Palpitations ,Low blood pressure
Respiratory distress
Pregnancy: The use of disulfiram during pregnancy is not recommended unless absolutely necessary. It falls under Category C for pregnancy (i.e., risk cannot be ruled out).
Storage:
Storage Conditions: Disulfiram powder should be stored in a cool, dry place, away from light and moisture. The storage conditions for the tablet form should also be followed according to the product's label.

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• Production Capacity: 20Mt
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We are offering high quality of Miconazole Nitrate .We are known for manufacturing, exporting, distributing, trading and supplying Miconazole Nitrate  in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Miconazole Nitrate  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of  Miconazole Nitrate . Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Miconazole Nitrate  as well as Intermediates of  Miconazole Nitrate . Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years. Shreeji Pharma International currently export Miconazole Nitrate  countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries. 

Miconazole Nitrate: Detailed Description

Overview

Miconazole nitrate is an antifungal medication used to treat various fungal infections of the skin, mouth, and vagina. It belongs to the imidazole class of antifungal agents and works by inhibiting the growth of fungi by interfering with the synthesis of ergosterol, an essential component of fungal cell membranes.

Chemical Information

IUPAC Name: (RS)-1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole nitrate

Molecular Formula: C18H14Cl4N2O4

Molecular Weight: 479.13 g/mol

CAS Number: 22832-87-7

Mechanism of Action

Miconazole nitrate inhibits the enzyme lanosterol 14α-demethylase, which is crucial for ergosterol biosynthesis in fungal cells. The disruption in ergosterol production compromises the integrity of the fungal cell membrane, leading to leakage of intracellular components and cell death.

Pharmacokinetics

Absorption: Minimal systemic absorption when applied topically or used as a vaginal cream.

Metabolism: Hepatic metabolism when absorbed.

Excretion: Primarily excreted via feces; minimal renal elimination.

Uses & Indications

Miconazole nitrate is used for the treatment of:

Fungal Skin Infections:

Athlete’s foot (Tinea pedis)

Jock itch (Tinea cruris)

Ringworm (Tinea corporis)

Cutaneous candidiasis

Vaginal Infections:

Vaginal candidiasis (yeast infection)

Oral Infections:

Oropharyngeal candidiasis (oral thrush)

Other Uses:

Seborrheic dermatitis (in some formulations)

Fungal nail infections (less commonly)

Dosage & Administration

Topical (Skin)

Cream/Ointment (2% Miconazole Nitrate): Apply twice daily for 2-4 weeks.

Powder/Spray: Used similarly to the cream for prevention and treatment.

Vaginal

Vaginal Cream (2% or 4% Miconazole Nitrate): Insert 5 g intravaginally at bedtime for 3-7 days.

Suppositories (100 mg, 200 mg, 1200 mg): Used for 1-7 days depending on strength.

Oral

Buccal Tablet (50 mg): Once daily for 14 days for oral thrush.

Side Effects

Common side effects include:

Skin irritation, burning, or itching (topical)

Vaginal irritation or discharge (vaginal)

Dry mouth, nausea (oral use)

 

 

 

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