Pharmaceutical Raw Material

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We are offering high quality of Glycofurol. We are known for manufacturing,exporting,distributing, trading and supplying Glycofurol in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Glycofurol in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier

of Glycofurol Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Glycofurol as well as Intermediates of Glycofurol.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Glycofurol to countries like Gulf Countries,South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries

Chemical Name: Tetrahydrofurfuryl alcohol polyethylene glycol ether
Common Name: Glycofurol
Synonyms: Tetrahydrofurfuryl polyethylene glycol ether; GF; PEG tetrahydrofurfuryl ether
CAS Number: 31692-85-0
Molecular Formula: Variable (polymeric compound)
Molecular Weight: Typically ~200–400 g/mol (depending on grade)
Appearance: Clear, colorless to pale yellow, viscous liquid or sometimes hygroscopic semi-solid (powdered or solidified form is rare and often hygroscopic)
Solubility: Miscible with water, ethanol, and other polar solvents
Storage Conditions: Store in a tightly closed container in a cool, dry place; protect from light and moisture

General Description:Glycofurol is a non-ionic solubilizer and solvent, derived from tetrahydrofurfuryl alcohol and polyethylene glycol (PEG). It is used mainly as a pharmaceutical excipient, especially in parenteral (injectable) drug formulations, where solubility enhancement of poorly soluble drugs is required.

Applications:

Pharmaceutical Grade:

Solvent for parenteral (injectable) formulations

Co-solvent in veterinary and human medicine

Vehicle for lipophilic drugs

Cosmetic and Industrial Use:

Solvent for fragrances and active ingredients

Carrier in cosmetic emulsions

Pharmacological Status:

Generally recognized as safe (GRAS) for specific applications

Not pharmacologically active by itself

Properties:

Non-toxic, biodegradable, and biocompatible

Low viscosity, good solubilizing capacity

Suitable for sterilization (autoclaving)

Side Effects (when used in formulations):

Usually minimal when used in appropriate concentrations

Rare: Local irritation at injection site

Not recommended for use in high systemic doses without proper evaluation

Precautions & Warnings:

Hygroscopic – should be stored in moisture-controlled conditions

Not to be used in formulations where PEGs are contraindicated

 

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• Delivery Time: immediate
• Packaging Details: drum pack

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We are offering high quality of Doxycycline sterile, We are known for manufacturing, exporting,distributing, trading and supplying Doxycycline sterile in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Doxycycline sterile in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Doxycycline sterile, Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Doxycycline sterile as well as Intermediates of Doxycycline sterile.
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Doxycycline sterile to countries like Gulf Countries,South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
 
 
Doxycycline Sterile Powder is a parenteral (injectable) form of the antibiotic Doxycycline, which is used primarily in hospital or clinical settings when oral administration is not possible, or when an immediate or more controlled therapeutic effect is required for serious infections.
Description:
Chemical Name: Doxycycline hyclate (for injectable forms, typically in its hydrochloride salt form).
Molecular Formula: C22H24N2O8 · HCl (doxycycline hyclate salt)
CAS Number: 24390-14-5 (doxycycline), 600-73-9 (doxycycline hydrochloride)
Appearance: The sterile powder is a white to off-white crystalline powder that is usually provided in vials intended for reconstitution before injection.
Solubility: It is soluble in water and can be reconstituted into a sterile solution suitable for intravenous (IV) infusion or intramuscular (IM) injection.
Uses:
Doxycycline Sterile Powder is used for treating a variety of serious bacterial infections that require parenteral (non-oral) antibiotic therapy: Respiratory Tract Infections:Pneumonia, Bronchitis, Sinusitis, Sexually Transmitted Infections (STIs): Chlamydia, Gonorrhea,Pelvic Inflammatory Disease (PID),Tick-borne Diseases:Lyme disease,Rocky Mountain spotted fever
Malaria: It can be used for the treatment and prevention of malaria, particularly in regions where other malaria treatments might be ineffective due to drug resistance.
Skin and Soft Tissue Infections: It is effective for treating cellulitis, abscesses, and acne.
Other Infections:
Meningitis
Sepsis
Urinary tract infections
Gastrointestinal infections
Side Effects:
Some common side effects of doxycycline sterile powder include:
Gastrointestinal issues: Nausea, vomiting, or abdominal discomfort.
Photosensitivity: Increased sensitivity to sunlight and an increased risk of sunburn.
Injection Site Reactions: Pain, redness, or irritation at the injection site.
Allergic Reactions: Rare, but reactions like rash, itching, or swelling may occur.
Storage:
Storage Conditions: Doxycycline Sterile Powder should be stored in a cool, dry place away from moisture and direct light. The vials should not be frozen. The powder should be used before the expiration date indicated on the packaging.
Purity:
Purity: Pharmaceutical-grade Doxycycline Sterile Powder typically has a purity of ≥ 98%. It is manufactured to meet the standards of recognized pharmacopeias such as the United States Pharmacopeia (USP) or the European Pharmacopoeia (EP).

Additional Information:

• Delivery Time: Immediate
• Packaging Details: 25 kg Drum pack.

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We are offering high quality of Parvaquone Api Powder. We are known for manufacturing, exporting, distributing, trading and supplying Parvaquone Api Powder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Parvaquone Api Powder in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Parvaquone Api Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who are manufacturing Parvaquone Api Powder as well as Intermediates of Parvaquone Api Powder.   

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently exports Parvaquone Api Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Parvaquone API powder is a veterinary medicine, specifically an antiprotozoal agent, used to treat and prevent theileriosis (East Coast fever) in animals, particularly cattle. 

1. General Overview: Parvaquone is a hydroxynaphthoquinone-based antiprotozoal compound used primarily in veterinary medicine. It is an active pharmaceutical ingredient (API) employed in the treatment of Theileriosis, a disease caused by protozoan parasites of the Theileria genus that affects cattle and other ruminants.

2. Chemical Information: IUPAC Name: 2-[(4-tert-Butylcyclohexyl) methyl]-3-hydroxy-1,4-naphthoquinone, Molecular Formula: C19H26O3, Molecular Weight: 302.41 g/mol, CAS Number: 59507-38-0, Appearance: Yellow to orange crystalline powder, Solubility: Slightly soluble in water, highly soluble in organic solvents like chloroform and methanol

Storage Conditions: Store in a cool, dry place away from light and moisture

3. Mechanism of Action: Parvaquone works by interfering with the electron transport chain in Theileria parasites, thereby inhibiting their mitochondrial function and leading to energy depletion.

4. Applications & Uses

Veterinary Use: Treats bovine Theileriosis, commonly caused by Theileria annulata and Theileria parva, Administered via intramuscular injection in affected animals, Often combined with supportive therapies like tick control to prevent reinfection.

Pharmaceutical API: Used in the formulation of veterinary medicines in injectable forms.

Available as raw material for veterinary pharmaceutical manufacturers.

5. Dosage & Administration: Standard Dosage: 20 mg/kg body weight, administered intramuscularly, Frequency: Usually given once, with a second dose after 48 hours if necessary.

6. Precautions & Side Effects: Precautions:Avoid use in animals with known hypersensitivity to Parvaquone, Do not administer intravenously, Ensure proper tick control measures to prevent reinfection.

Side Effects: Mild swelling at the injection site, Rare allergic reactions in sensitive animals, Temporary loss of appetite or lethargy.

Storage Life: Typically has a shelf life of 2-3 years if stored properly in a dry, cool place.

7. Regulatory Status: Approved for veterinary use in many countries.

Compliance with standards such as GMP (Good Manufacturing Practices) and ISO certifications is necessary for API manufacturers.

Additional Information:

• Item Code: 29334900
• Delivery Time: immediate
• Packaging Details: HDPE DRUM PACK

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We are offering high quality of Guaifenesin Powder. We are known for manufacturing, exporting, distributing, trading and supplying GuaifenesinPowder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier GuaifenesinPowder in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Guaifenesin Powder

Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing GuaifenesinPowder  as well as Intermediates of  GuaifenesinPowder.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export GuaifenesinPowder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

 Guaifenesin is a medication primarily used as an expectorant to help relieve chest congestion. Here's a breakdown of its technical details:

Chemical Information:

IUPAC Name: 3-(2-methoxyphenoxy)-1,2-propanediol

Molecular Formula: C10H14O4

Molar Mass: 198.22 g/mol

CAS Number: 93-14-1

Uses:

Chest Congestion: It’s commonly used to relieve symptoms of chest congestion caused by respiratory infections.

Cough: Guaifenesin is often combined with other medications (such as dextromethorphan or antihistamines) in products meant to treat cough and cold.

Bronchitis and other respiratory conditions: It is beneficial in reducing the discomfort associated with these conditions.

 Forms Available: Guaifenesin is available in various forms, including:

Oral tablets and capsules

Syrups

Extended-release formulations

Granules and powder for reconstitution in liquid form

 Side Effects: Guaifenesin is generally well-tolerated, but some people may experience side effects, including:

Nausea ,Vomiting, Dizziness, Headache, Rash

Stomach upset Although rare, more severe allergic reactions could occur, leading to symptoms such as swelling, difficulty breathing, or hives. If any of these symptoms appear, seek immediate medical attention.

 Precautions and Warnings:

Pregnancy and Breastfeeding: Guaifenesin is considered safe to use during pregnancy, but always consult with a healthcare provider before using it. It is excreted in breast milk, so caution is advised if breastfeeding.

Kidney or Liver Problems: People with kidney or liver conditions should consult their doctor before using guaifenesin, as their body may process the drug differently.

Other Medications: It is important to check with a healthcare provider before using guaifenesin, especially if you are taking other medications, as drug interactions are possible.

 Effectiveness: Guaifenesin's effectiveness in relieving chest congestion can vary. Some studies suggest that it may only modestly improve symptoms compared to a placebo, though many people find relief from their symptoms with its use. If symptoms persist, it’s advisable to consult a healthcare provider.

Guaifenesin is a widely-used and generally safe expectorant to relieve chest congestion. 

 

Additional Information:

• Item Code: 62011-0382-1
• Production Capacity: 5000
• Delivery Time: prompt
• Packaging Details: drum

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We are offering high quality of Caffeine anhydrous We are known for  manufacturing ,exporting, distributing, trading and supplying Caffeine anhydrous in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Caffeine anhydrous in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of  Caffeine anhydrous onwadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Caffeine anhydrous as well as Intermediates of Caffeine anhydrous
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Caffeine anhydrous to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries.
Caffeine anhydrous is a dehydrated form of caffeine, typically in the form of a fine, white powder. It is a stimulant commonly used in various dietary supplements, particularly those aimed at enhancing energy, focus, and performance. Here’s a more detailed breakdown of caffeine anhydrous:
1. Form and Composition:
Dehydrated Caffeine: "Anhydrous" means "without water." The caffeine in this form is processed to remove the water content, making it more concentrated than regular caffeine found in coffee, tea, or energy drinks.
Appearance: It usually appears as a white, crystalline powder.
2. Uses:
Energy Boost: Caffeine anhydrous is primarily used for its stimulating effects, providing a quick energy boost and increasing alertness.
Fat Loss: It’s often included in weight loss and fat-burning supplements due to its ability to increase thermogenesis (heat production in the body) and improve metabolic rate.
Enhanced Focus and Cognitive Performance: Caffeine anhydrous is also used for improving mental clarity, focus, and cognitive function, especially in individuals who need to maintain attention during physical activities or mental tasks.
Sports Performance: It is frequently included in pre-workout supplements because it may enhance physical performance by improving endurance, strength, and reducing the perception of effort.
3. Mechanism of Action:
Caffeine Effects: Like other forms of caffeine, caffeine anhydrous works by blocking adenosine receptors in the brain, which normally promote relaxation and sleep. By inhibiting adenosine, caffeine promotes wakefulness, alertness, and a feeling of increased energy.
Stimulating the Central Nervous System (CNS): This increases the release of neurotransmitters like dopamine and norepinephrine, leading to improved focus, mood, and overall cognitive function.
4. Dosage and Safety:
Effective Dosage: The typical dosage of caffeine anhydrous varies, but it’s usually between 100 mg to 200 mg per serving in supplements. It’s important to be cautious, as the potency of caffeine anhydrous is higher than that of a typical cup of coffee.
Caffeine Sensitivity: Individuals who are sensitive to caffeine may experience jitteriness, anxiety, or insomnia, especially if taken in high doses. It’s important to follow recommended dosages.
Side Effects: Common side effects include anxiety, rapid heartbeat (tachycardia), dehydration, and digestive issues like nausea if consumed in excessive amounts.

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• Delivery Time: immediate
• Packaging Details: drum pack

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We are offering high quality of Calcium Sennosides We are known for manufacturing,exporting, distributing, trading and supplying Calcium Sennosides in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Calcium Sennosides in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Calcium Sennosides Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Calcium Sennosides as well as Intermediates of Calcium SennosidesShreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Calcium Sennosides to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries.
Calcium Saccharate is a calcium salt of saccharic acid (also known as saccharate), commonly used as a calcium supplement in various applications, including in the food industry and as a dietary supplement. Here's a detailed breakdown:

1. Chemical Structure and Composition
Chemical Formula: C12H22CaO14
It is a calcium salt derived from saccharic acid, which is a sugar-derived organic acid. Saccharate is the product of oxidation of sugars like glucose, where the aldehyde group is converted into a carboxyl group.
2. Physical Properties
Appearance: It typically appears as a white or off-white crystalline powder.
Solubility: It is soluble in water, which makes it useful in various liquid-based formulations.
Taste: Calcium saccharate is generally considered tasteless or has a slightly sweet flavor due to the saccharic acid component.
3. Uses and Applications
Dietary Supplement: Calcium saccharate is used as a source of calcium in dietary supplements. Calcium is an essential mineral for bone health, muscle function, and various biochemical processes in the body.
Food Industry: It can be used in food processing as a calcium fortifying agent. It is especially useful in products aimed at providing calcium without altering the taste or texture significantly.
Pharmaceuticals: Sometimes it is incorporated into pharmaceutical formulations to provide a stable source of calcium in liquid medications or syrups.
4. Benefits of Calcium Saccharate
Bone Health: As a source of calcium, it supports bone and dental health.
Calcium Absorption: Calcium saccharate, being soluble in water, is relatively easy for the body to absorb, making it a convenient option for calcium supplementation.
Non-Irritating: Unlike some other calcium salts, calcium saccharate is often less irritating to the gastrointestinal system.
5. Safety and Dosage
It is generally regarded as safe when used as directed in dietary supplements and food products.
The recommended dosage varies depending on the age and specific health needs of the individual. However, excessive intake of calcium can lead to adverse effects, such as kidney stones or hypercalcemia (excess calcium in the blood).
6. Other Information
Synthesis: Calcium saccharate can be synthesized through a process where calcium is reacted with saccharic acid or its derivatives.
Storage: It should be stored in a cool, dry place to maintain its stability and prevent any degradation.

Additional Information:

• Production Capacity: 5000 kg
• Delivery Time: prompt
• Packaging Details: 25 kg drum

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We are offering high quality of Yohimbin Hcl . We are known for manufacturing, exporting, distributing, trading and supplying Yohimbin Hcl   in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Yohimbin Hcl   in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
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Shreeji Pharma International currently export Yohimbin Hcl  to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
 
Yohimbine Hydrochloride (Yohimbine HCl) is a medication and natural alkaloid derived from the bark of the Yohimbe tree (Pausinystalia johimbe), native to West Africa. It is primarily known for its use as a sympatholytic agent and alpha-2 adrenergic antagonist, with applications in medicine, weight loss, and erectile dysfunction treatment.
Yohimbine HCl is available as a prescription drug in some countries and is also used in herbal supplements and over-the-counter products, although its efficacy and safety are debated.
General Information:
Chemical Name: 3-[(1,2-dihydroxypropyl)amino]-1-ethylindole.
Molecular Formula: C21H26ClN2O3.
CAS Number: 65-19-0.
Brand Names: Yocon, Yohimbe, and others (under prescription).
Drug Class: Alpha-2 adrenergic antagonist, sympatholytic.
Storage:
Yohimbine should be stored in a cool, dry place and kept out of reach of children.
Ensure the medication is in its original packaging to prevent contamination.
Erectile Dysfunction (ED):
Yohimbine is one of the most commonly known uses in treating erectile dysfunction, particularly when the dysfunction is due to psychological causes. It can help increase blood flow to the penis by blocking the alpha-2 adrenergic receptors and thereby improving erectile function.
Yohimbine HCl is sometimes prescribed by doctors as a treatment for ED, particularly when other medications like sildenafil (Viagra) are not effective or appropriate.
Side Effects:
While yohimbine can be beneficial for certain conditions, it also has potential side effects, especially when taken in large doses or without medical supervision:
Common Side Effects:
Increased heart rate (tachycardia).
Elevated blood pressure (hypertension).
Anxiety or nervousness due to its stimulating effects.
Dizziness or light-headedness.
Headache.
Upset stomach or gastrointestinal discomfort, such as nausea or vomiting.
Sweating.
Precautions:
Heart and Blood Pressure Issues:
Yohimbine should be used cautiously in people with a history of heart disease, high blood pressure, or arrhythmias because it can cause increased heart rate and elevated blood pressure.
Mental Health Conditions:
 People with anxiety, nervousness

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We are offering high quality of Hyoscine Butylbromide Powder. We are known for manufacturing, exporting, distributing, trading and supplying Hyoscine Butylbromide Powder in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Hyoscine Butylbromide Powder in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Hyoscine Butylbromide Powder. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Hyoscine Butylbromide Powder as well as Intermediates of Hyoscine Butylbromide Powder.

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Shreeji Pharma International currently export Hyoscine Butylbromide Powder to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Hyoscine Butylbromide (also known as Scopolamine Butylbromide) is a synthetic anticholinergic agent commonly used to treat symptoms related to motion sickness, gastrointestinal disorders, and to relieve spasms. It acts by blocking the action of acetylcholine, a neurotransmitter that plays a key role in muscle contraction, which in turn helps to relieve smooth muscle spasms.

Here are some technical details about Hyoscine Butylbromide:

Chemical Information:

IUPAC Name: (3α)-1-(3-Butyl-1-hydroxy-2-phenylpropyl)-3-hydroxy-2,5-dihydroxy-1H-pyrrolo[2,3-b]quinolizine bromide

Molecular Formula: C17H22BrNO4

Molecular Weight: 374.27 g/mol

CAS Number: 149-64-4

Mechanism of Action:

Hyoscine Butylbromide works as an anticholinergic agent. It selectively blocks muscarinic receptors in the smooth muscles, particularly in the gastrointestinal tract, urinary tract, and other areas with smooth muscle. This action reduces involuntary muscle contractions, providing relief from conditions like cramps or spasms.

It also has minimal effects on the central nervous system (CNS) as it does not cross the blood-brain barrier effectively.

Indications:

Treatment of gastrointestinal spasm, irritable bowel syndrome (IBS), and other conditions causing spasms of the GI tract.

Management of motion sickness.

Relief of spasms of the urinary tract.

Sometimes used in preoperative settings to reduce the risk of salivation or excessive gastrointestinal secretion during surgery.

Dosage:

The typical adult dose of Hyoscine Butylbromide can vary depending on the condition being treated.

For gastrointestinal disorders: 10-20 mg, 3-5 times daily.

For motion sickness: A typical dose of 10-20 mg taken 30 minutes before travel.

Injectable form may be used in emergency situations or hospital settings.

Side Effects:

Dry mouth, Blurred vision, Dizziness or drowsiness

Constipation, Difficulty urinating

Precautions and Contraindications:

Should be used with caution in patients with glaucoma, myasthenia gravis, urinary retention, or prostatic hypertrophy.

Pregnancy Category C (use only if clearly needed and prescribed).

Not recommended for children under 6 years of age.

Use with caution in elderly patients.

 

 

Additional Information:

• Production Capacity: 400 kg
• Delivery Time: prompt
• Packaging Details: 1kg / 2kg / 5kg drum pack

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We are offering high quality of Ropinirol Hydrochloride. We are known for manufacturing, exporting, Distributing, trading and supplying Ropinirol Hydrochloride in Gujarat, India. Further, this is safely Packaged by our professionals in diverse packaging options that maintain its purity and Effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Ropinirol Hydrochloride in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier

of Ropinirol Hydrochloride Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Ropinirol Hydrochloride as well as Intermediates of Ropinirol Hydrochloride.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Ropinirol Hydrochloride to countries like Gulf Countries,South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries

Ropinirole Hydrochloride is a synthetic non-ergoline dopamine agonist primarily used in the treatment of Parkinson’s disease and Restless Legs Syndrome (RLS). It mimics the action of dopamine in the brain, which is typically deficient in patients suffering from these conditions. By stimulating dopamine D2 and D3 receptors, ropinirole helps to improve motor control and reduce symptoms associated with dopamine deficiency.

IUPAC Name: 4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride

Molecular Formula: C16H24N2O · HCl

Molecular Weight: 296.84 g/mol (free base: 260.38 g/mol)

CAS Number: 91374-20-8 (base), 122469-92-9 (hydrochloride salt)

Structure:

Core: Indolone (indole-2-one)

Substituents: Dipropylaminoethyl side chain

2. Physical and Chemical Properties

Appearance: White to off-white crystalline powder

Solubility: Soluble in water, methanol; slightly soluble in ethanol

Melting Point: ~243–250°C (hydrochloride salt)

pKa: ~7.8

Stability: Stable under recommended storage conditions (cool, dry place, protected from light)

Mechanism of Action:Ropinirole binds selectively to dopamine D2-like receptors (D2 and D3) and acts as an agonist. It stimulates these receptors in the striatum and substantia nigra, improving dopaminergic transmission in patients with Parkinson’s disease.

Absorption:Rapidly absorbed from the gastrointestinal tract with a bioavailability of 55%. Peak plasma concentrations (Tmax) occur within 1–2 hours for immediate-release formulations.

Half-life:Approximately 6 hours (immediate-release); prolonged in extended-release forms.

Metabolism:Extensively metabolized in the liver by cytochrome P450 enzyme CYP1A2.

Elimination:Excreted primarily in the urine as inactive metabolites.

Clinical Uses

Parkinson's Disease : Used as monotherapy in early Parkinson’s disease or as adjunct therapy with levodopa in advanced cases.

Restless Legs Syndrome (RLS) : Reduces the discomfort and urge to move the legs, particularly during rest or at night.

Conclusion: Ropinirole Hydrochloride is a well-established dopaminergic agent with proven efficacy in managing movement disorders. Its pharmacological profile, including its selective receptor affinity and flexible dosing forms, makes it a valuable option for long-term therapy in Parkinson’s disease and RLS.

Additional Information:

• Delivery Time: IMMEDIATE
• Packaging Details: DRUM PACK

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We are offering high quality of Marbofloxacin Powder  We are known for manufacturing, exporting, distributing, trading and supplying Marbofloxacin Powder  in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Marbofloxacin Powder in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Marbofloxacin Powder . Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Marbofloxacin Powder  as well as Intermediates of Marbofloxacin Powder   

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Marbofloxacin Powder  to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Marbofloxacin Powder - Detailed Description

Overview:

Marbofloxacin is a synthetic, broad-spectrum fluoroquinolone antibiotic used in veterinary medicine. It is effective against a wide range of Gram-negative and some Gram-positive bacteria. The powder form is commonly used for formulation into oral suspensions, injections, or medicated feeds.

Chemical Information:

Chemical Name: Marbofloxacin

Molecular Formula: C17H19FN4O4

Molecular Weight: 362.36 g/mol

CAS Number: 115550-35-1

Appearance: White to off-white crystalline powder

Solubility: Slightly soluble in water, soluble in organic solvents

Mode of Action:

Marbofloxacin inhibits bacterial DNA gyrase, an essential enzyme for DNA replication and transcription, leading to bacterial cell death. It is bactericidal and concentration-dependent in action.

Pharmacokinetics:

Absorption: Rapidly absorbed after oral or injectable administration

Distribution: Well-distributed in tissues, particularly lungs, liver, kidneys, and the gastrointestinal tract

Metabolism: Partially metabolized in the liver

Excretion: Primarily excreted via urine and bile

Indications:

Marbofloxacin powder is used in animals, particularly in:

Dogs & Cats: Treatment of bacterial skin infections, urinary tract infections (UTIs), and respiratory infections.

Cattle: Control of respiratory infections caused by Mannheimia haemolytica and Pasteurella multocida.

Swine & Poultry: Treatment of bacterial infections, including colibacillosis.

Aquaculture (Fish & Shrimp): Used in medicated feeds to treat bacterial infections.

Dosage & Administration:

Oral: Typically mixed in drinking water or feed, dosage varies by species and severity of infection.

Injectable: Given subcutaneously (SC) or intramuscularly (IM) in large animals.

Aquaculture: Mixed into feed at prescribed concentrations.

(Exact dosage should be determined by a veterinarian.)

Adverse Effects:

Gastrointestinal disturbances (vomiting, diarrhea)

Potential cartilage damage in young animals

CNS effects (seizures, tremors in rare cases)

 

Additional Information:

• Delivery Time: immediate
• Packaging Details: HDPE DRUM PACK

Product Details:

We are offering high quality of Colchicine We are known for manufacturing,exporting, distributing, trading and supplying Colchicine in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Colchicine in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports.Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Colchicine Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Colchicine as well as Intermediates of Colchicine

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.Shreeji Pharma International currently export Colchicine to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central American Countries and in European countries
Colchicine (pharmaceutical grade) is a medication primarily used to treat gout and Familial Mediterranean Fever (FMF), as well as for managing certain types of pericarditis. It is derived from the Colchicum autumnale plant, commonly known as the autumn crocus. Colchicine has been used for centuries, although it is most well-known today for its use in the management of gout flares

Chemical Information:

Chemical Name: Colchicine

Molecular Formula: C22H25NO6

CAS Number: 64-86-8

IUPAC Name: (R)-2-(3,4-dimethoxyphenyl)-1,2-dihydro-3,5-dimethoxy-4-(methylamino)-1H-pyrrolo[3,4-b]quinazoline-1,5-dione

Appearance: Pharmaceutical-grade colchicine typically comes as white to off-white crystalline powder.

Solubility: Colchicine is slightly soluble in water but is soluble in alcohol and chloroform.
Dosage and Administration:

The dosage of colchicine can vary depending on the condition being treated, as well as the patient's overall health and response to the medication.
Side Effects:

While colchicine is effective, it can cause several side effects. Some of the common side effects include:

Gastrointestinal Issues: Diarrhea, nausea, vomiting, abdominal pain, and cramping are common side effects, especially at higher doses.

Bone Marrow Suppression: Prolonged use of colchicine or high doses can cause bone marrow suppression, leading to low white blood cell count, low red blood cell count, or low platelet count.

Liver Toxicity: In rare cases, colchicine can cause liver toxicity, which may lead to jaundice or abnormal liver function tests.

Muscle Weakness: High doses may cause muscle weakness or rhabdomyolysis (breakdown of muscle tissue), which can be severe.

Precautions and Contraindications:

Renal and Hepatic Impairment: Colchicine is primarily excreted by the liver and kidneys. People with liver or kidney diseases should use colchicine with caution, as dose adjustments may be necessary.

Pregnancy and Lactation: Colchicine is generally not recommended during pregnancy, especially in the first trimester. It may be used during pregnancy only if the potential benefit outweighs the potential risk. It is also excreted in breast milk, so caution should be used when nursing.

Storage:
Colchicine should be stored in a cool, dry place away from moisture and light.
It should be kept at room temperature and out of the reach of children.
Pharmaceutical-grade colchicine refers to colchicine that is produced to the strict standards required for use in medicine, ensuring purity, potency, and safety. 

Additional Information:

• Production Capacity: 400 kg
• Delivery Time: prompt
• Packaging Details: 1 / 2 / 5/ 25 kgs drum pack

Product Details:

We are offering high quality of Thiocolchicoside. We are known for manufacturing, exporting, distributing, trading and supplying Thiocolchicoside  in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.
Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Thiocolchicoside  in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.
Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Thiocolchicoside. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Thiocolchicoside as well as Intermediates of Thiocolchicoside.  
Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.
Shreeji Pharma International currently export Thiocolchicoside to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.
 
Thiocolchicoside is a muscle relaxant and anti-inflammatory agent that is derived from colchicine, a natural product found in the autumn crocus (Colchicum autumnale). It is commonly used in the treatment of musculoskeletal disorders, particularly for conditions involving muscle spasms and inflammation.
Description & Properties:
Chemical Formula: C17H21NO6S
Molecular Weight: 367.42 g/mol
Appearance: White to off-white crystalline powder, odorless or nearly odorless.
Solubility: Sparingly soluble in water, soluble in organic solvents like ethanol and methanol.
Melting Point: Approximately 215°C to 220°C.
Mechanism of Action:
Thiocolchicoside exerts its effects through its muscle relaxant and anti-inflammatory properties. It works by binding to and inhibiting the action of glycine receptors, which are involved in the control of motor neurons. By doing so, it reduces muscle tone and spasticity, making it effective in treating muscle spasms.
It also has an anti-inflammatory effect, which helps in reducing pain and inflammation associated with musculoskeletal disorders.
Uses:
Thiocolchicoside is primarily used for its muscle relaxant and anti-inflammatory effects, especially in the following conditions:
Muscle Spasms: It is commonly prescribed to treat acute back pain, neck pain, and other musculoskeletal conditions that involve muscle spasms.
Side Effects:
While generally well-tolerated, Thiocolchicoside can cause some side effects, including:
Gastrointestinal issues: Such as nausea, vomiting, or stomach upset.
Drowsiness or dizziness: As a muscle relaxant, it may cause drowsiness or lightheadedness.
Allergic reactions: Rashes, itching, or more severe allergic reactions (though rare).
Liver issues: Liver toxicity is a concern with prolonged use, so liver function should be monitored in patients on long-term therapy.
Precautions:
Pregnancy and Lactation: Thiocolchicoside is generally avoided during pregnancy due to potential adverse effects on the fetus. It is also advised to avoid using it while breastfeeding unless deemed absolutely necessary.
Liver Function: Caution should be exercised in individuals with liver disease or impaired liver function.
Drug Interactions: Thiocolchicoside may interact with other medications, especially those that affect the central nervous system (like sedatives or alcohol), increasing the risk of drowsiness or sedation.
Storage:
Storage conditions: Store in a cool, dry place, away from light and moisture.

 

 

Additional Information:

• Production Capacity: 200 kg
• Delivery Time: prompt
• Packaging Details: 1 / 2 / 5kgs drum pack